Showing 1-20 of 20 results for "277541"
Sarah Nicolai et al.
Science immunology, 5(43) (2020-01-05)
During industrialization, humans have been exposed to increasing numbers of foreign chemicals. Failure of the immune system to tolerate drugs, cosmetics, and other skin products causes allergic contact dermatitis, a T cell-mediated disease with rising prevalence. Models of αβ T...
Tetrahedron Letters, 34, 1721-1721 (1993)
Synthesis of cecropia juvenile hormone from trans,trans-farnesol.
E E van Tamelen et al.
Journal of the American Chemical Society, 92(3), 737-738 (1970-02-11)
Roman Shchepin et al.
Bioorganic & medicinal chemistry, 16(4), 1842-1848 (2007-11-27)
A series of synthetic molecules combining a geranyl backbone with a heterocyclic or oxime head group are quorum-sensing molecules that block the yeast to mycelium transition in the dimorphic fungus Candida albicans. A number of the analogs have an IC50...
Release Behavior of Trans, Trans-Farnesol Entrapped in Amorphous Silica Capsules
Filipa, L., et al.
Research in Pharmaceutical Sciences, 2, 52-56 (2012)
Melanie L Langford et al.
Antimicrobial agents and chemotherapy, 54(2), 940-942 (2009-11-26)
Farnesol interacts with Candida albicans as both a quorum-sensing molecule and toxic agent, but confusion abounds regarding which conditions promote these distinct responses. Farnesol sensitivity was measured when inoculum cell history and size, temperature, and growth media were altered. Parameters...
Fu Chen et al.
Antimicrobial agents and chemotherapy, 53(11), 4898-4902 (2009-08-26)
Maintenance of the effective local concentration of antimicrobials on the tooth surface is critical for the management of cariogenic bacteria in the oral cavity. We report on the design of a simple tooth-binding micellar drug delivery platform that would effectively...
Influences of trans-trans farnesol, a membrane-targeting sesquiterpenoid, on Streptococcus mutans physiology and survival within mixed-species oral biofilms
Jeon J-G, et al.
International Journal of Oral Science, 3, 98-106 (2011)
Tristan Rossignol et al.
Antimicrobial agents and chemotherapy, 51(7), 2304-2312 (2007-08-09)
In Candida albicans, the quorum-sensing molecule farnesol inhibits the transition from yeast to hyphae but has no effect on cellular growth. We show that the addition of exogenous farnesol to cultures of Candida parapsilosis causes the cells to arrest, but...
Nobuwa Aoki et al.
Journal of natural products, 71(7), 1308-1310 (2008-06-19)
An ethyl acetate-soluble fraction of a methanol extract from the stems of Angelica keiskei was subjected to chromatographic separation to give three new chalcones, designated as xanthokeismins A-C (1-3), in addition to a known chalcone, xanthoangelol B (4). The structures...
Avinash Pandreka et al.
BMC plant biology, 15, 214-214 (2015-09-04)
Neem tree (Azadirachta indica) is one of the richest sources of skeletally diverse triterpenoids and they are well-known for their broad-spectrum pharmacological and insecticidal properties. However, the abundance of Neem triterpenoids varies among the tissues. Here, we delineate quantitative profiling...
Mark E Shirtliff et al.
Antimicrobial agents and chemotherapy, 53(6), 2392-2401 (2009-04-15)
Farnesol, a precursor in the isoprenoid/sterol pathway, was recently identified as a quorum-sensing molecule produced by the fungal pathogen Candida albicans. Farnesol is involved in the inhibition of germination and biofilm formation by C. albicans and can be cytotoxic at...
Assessment of the antioxidant and antiproliferative effects of sesquiterpenic compounds in in vitro Caco-2 cell models
Vinholes Juliana, et al.
Food Chemistry, 156, 204-211 (2014)
The Journal of Organic Chemistry, 59, 5803-5803 (1994)
Tetrahedron, 49, 2457-2457 (1993)
Tetrahedron, 50, 139-139 (1994)
Marek Jindra et al.
PLoS genetics, 11(7), e1005394-e1005394 (2015-07-15)
Juvenile hormones (JHs) play a major role in controlling development and reproduction in insects and other arthropods. Synthetic JH-mimicking compounds such as methoprene are employed as potent insecticides against significant agricultural, household and disease vector pests. However, a receptor mediating...
Ulrike Grienke et al.
Journal of medicinal chemistry, 53(2), 778-786 (2009-12-18)
At present, neuraminidase (NA) inhibitors are the mainstay of pharmacological strategies to fight against global pandemic influenza. In the search for new antiviral drug leads from nature, the seed extract of Alpinia katsumadai has been phytochemically investigated. Among the six...
Rosa Perestrelo et al.
Foods (Basel, Switzerland), 8(12) (2019-12-07)
Terpenoids, including monoterpenoids (C10), norisoprenoids (C13), and sesquiterpenoids (C15), constitute a large group of plant-derived naturally occurring secondary metabolites with highly diverse chemical structures. A quantitative structure-activity relationship (QSAR) model to predict terpenoid toxicity and to evaluate the influence of...
Fangfang Zeng et al.
Insect biochemistry and molecular biology, 113, 103213-103213 (2019-08-24)
Mosquitoes rely heavily on the olfactory system to find a host for a bloodmeal, plants for a source of energy and suitable sites for oviposition. Here, we examined a cluster of eight odorant receptors (ORs), which includes one OR, CquiOR1...

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