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Showing 1-30 of 351 results for "295876" within Papers
Sibilla D'Anteo et al.
Environmental technology, 36(24), 3159-3166 (2015-05-29)
A membrane bioreactor (MBR), fed with domestic wastewater, was bioaugmented with nitrifying biomass selected in a side-stream MBR fed with a synthetic high nitrogen-loaded influent. Microbial communities evolution was monitored and comparatively analysed through an extensive bio-molecular investigation (16S rRNA
Myong-Ho Jeong et al.
Nature communications, 5, 5455-5455 (2014-11-20)
Canonical Wnt signalling regulates expansion of neural progenitors and functions as a dorsalizing signal in the developing forebrain. In contrast, the multifunctional co-receptor Cdo promotes neuronal differentiation and is important for the function of the ventralizing signal, Shh. Here we
S Martín et al.
International journal for parasitology, 45(13), 831-840 (2015-08-05)
The limitations associated with the use of anthelmintic drugs in the control of gastrotintestinal nematodosis, such as the emergence of anthelmintic resistance, have stimulated the study of the immunological control of many parasites. In the case of Haemonchus contortus, several
Stine Mencl et al.
Journal of neuroimmunology, 274(1-2), 125-131 (2014-08-02)
Inflammation is a pathological hallmark of traumatic brain injury (TBI). Recent evidence suggests that immune cells such as lymphocytes are of particular relevance for lesion development after TBI. FTY720, a sphingosine-1-phosphate (S1P) receptor modulator, sequesters T lymphocytes in lymphoid organs
Markus W Tackenberg et al.
International journal of pharmaceutics, 478(2), 597-605 (2014-12-17)
Essential oils and other liquid active pharmaceutical ingredients (APIs) are frequently microencapsulated to improve shelf life, handling, and for tailoring release. A glassy solid solution (GSS), a single-phase system, where the excipient is plasticized by the API, could be an
Chenyang Zhao et al.
Journal of immunology (Baltimore, Md. : 1950), 193(2), 879-888 (2014-06-13)
The impact of environmental stressors on the magnitude of specific chemokine gene expression was examined in mouse bone marrow-derived macrophages stimulated through various TLRs. Levels of TLR-stimulated CXCL1 and CXCL2 but not CXCL10 or CCL5 mRNAs were selectively enhanced (>10-fold)
Robert Duran et al.
Environmental science and pollution research international, 22(20), 15215-15229 (2015-02-26)
The exploration of marine Actinobacteria has as major challenge to answer basic questions of microbial ecology that, in turn, will provide useful information to exploit Actinobacteria metabolisms in biotechnological processes. The ecological functions performed by Actinobacteria in marine sediments are
Marwa Ahmed et al.
Journal of chromatography. A, 1360, 100-109 (2014-08-19)
Single-walled carbon nanotubes were encapsulated into different polymer-based monolithic backbones. The polymer monoliths were prepared via the copolymerization of 20% monomers, glycidyl methacrylate, 20% ethylene glycol dimethacrylate and 60% porogens (36% 1-propanol, 18% 1,4-butanediol) or 16.4% monomers (16% butyl methacrylate
Elaine Y Liu et al.
Acta neuropathologica, 128(4), 525-541 (2014-05-09)
Hexanucleotide repeat expansions of C9orf72 are the most common genetic cause of amyotrophic lateral sclerosis and frontotemporal degeneration. The mutation is associated with reduced C9orf72 expression and the accumulation of potentially toxic RNA and protein aggregates. CpG methylation is known
Jodie Birch et al.
American journal of physiology. Lung cellular and molecular physiology, 309(10), L1124-L1137 (2015-09-20)
Cellular senescence has been associated with the structural and functional decline observed during physiological lung aging and in chronic obstructive pulmonary disease (COPD). Airway epithelial cells are the first line of defense in the lungs and are important to COPD
Melissa Mancini et al.
The Journal of molecular diagnostics : JMD, 17(2), 179-184 (2015-01-03)
DNMT3A mutations represent one of the most frequent gene alterations detectable in acute myeloid leukemia with normal karyotype. Although various recurrent somatic mutations of DNMT3A have been described, the most common mutation is located at amino acid R882 in the
Miranda M Gray et al.
Molecular ecology, 23(24), 6011-6028 (2014-11-06)
Big bluestem (Andropogon gerardii) is an ecologically dominant grass with wide distribution across the environmental gradient of U.S. Midwest grasslands. This system offers an ideal natural laboratory to study population divergence and adaptation in spatially varying climates. Objectives were to:
Casimiro Gerarduzzi et al.
Journal of proteome research, 13(11), 5262-5280 (2014-09-17)
The Prostaglandin E2 (PGE2) signaling mechanism within fibroblasts is of growing interest as it has been shown to prevent numerous fibrotic features of fibroblast activation with limited evidence of downstream pathways. To understand the mechanisms of fibroblasts producing tremendous amounts
Luana S Maroja et al.
G3 (Bethesda, Md.), 5(11), 2219-2227 (2015-08-28)
Characterizing the extent of genomic differentiation between recently diverged lineages provides an important context for understanding the early stages of speciation. When such lineages form discrete hybrid zones, patterns of differential introgression allow direct estimates of which genome regions are
Li-Di Xu et al.
PloS one, 9(11), e111125-e111125 (2014-11-08)
The p53 target gene WIG-1 (ZMAT3) is located in chromosomal region 3q26, that is frequently amplified in human tumors, including cervical cancer. We have examined the status of WIG-1 and the encoded Wig-1 protein in cervical carcinoma cell lines and
A unified mechanism for abiotic adenine and purine synthesis in formamide.
Jeremy S Hudson et al.
Angewandte Chemie (International ed. in English), 51(21), 5134-5137 (2012-04-11)
Kathleen Vrolix et al.
Journal of autoimmunity, 52, 101-112 (2014-01-21)
Myasthenia gravis (MG) with antibodies against the acetylcholine receptor (AChR-MG) is considered as a prototypic autoimmune disease. The thymus is important in the pathophysiology of the disease since thymus hyperplasia is a characteristic of early-onset AChR-MG and patients often improve
Ileana Soto et al.
PLoS biology, 13(10), e1002279-e1002279 (2015-10-30)
Aging is the major risk factor for neurodegenerative diseases such as Alzheimer's disease, but little is known about the processes that lead to age-related decline of brain structures and function. Here we use RNA-seq in combination with high resolution histological
Ayala Tamir et al.
Journal of ovarian research, 7, 109-109 (2014-12-06)
Early detection of ovarian cancer remains a challenge due to widespread metastases and a lack of biomarkers for early-stage disease. This study was conducted to identify relevant biomarkers for both laparoscopic and serum diagnostics in ovarian cancer. Bioinformatics analysis and
Esther Ingold et al.
Biology open, 4(2), 146-154 (2015-01-13)
The formation of functional neuronal circuits relies on accurate migration and proper axonal outgrowth of neuronal precursors. On the route to their targets migrating cells and growing axons depend on both, directional information from neurotropic cues and adhesive interactions mediated
T Phaechamud et al.
Indian journal of pharmaceutical sciences, 77(1), 62-74 (2015-03-15)
The objective of this investigation was to prepare the shellac wax matrix tablets by fusion and molding technique incorporated with Lutrol in different ratios to modify the hydrophobicity of matrix tablet. The matrix tablets with single drug were loaded either
Benjamin Vandendriessche et al.
BMC physiology, 14, 5-5 (2014-09-05)
MAPK-activated protein kinase 2 (MK2) plays a pivotal role in the cell response to (inflammatory) stress. Among others, MK2 is known to be involved in the regulation of cytokine mRNA metabolism and regulation of actin cytoskeleton dynamics. Previously, MK2-deficient mice
Amal Lamraoui et al.
Inflammation, 37(5), 1689-1704 (2014-05-27)
The inflammatory response caused by scorpion venoms is a key event in the pathogenesis of scorpion envenomation. This response was assessed in the cardiac, pulmonary, and gastric tissues of envenomed mice. The results reveal an increase of permeability in cardiac
Dongliang Xiong et al.
Plant, cell & environment, 38(12), 2541-2550 (2015-04-30)
Photosynthesis in C3 plants is significantly limited by mesophyll conductance (gm ), which can vary with leaf anatomical traits and nitrogen (N) supplements. Several studies have investigated the response of gm to N supplements; however, none examined the implications of
Zilin Nie et al.
Nature communications, 6, 5908-5908 (2015-01-09)
MALT1 is the only known paracaspase and is a critical mediator of B- and T-cell receptor signalling. The function of the MALT1 gene is subverted by oncogenic chimeric fusions arising from the recurrent t(11;18)(q21;q21) aberration, which is the most frequent
Takeshi Taniguchi et al.
The Journal of general and applied microbiology, 61(5), 193-202 (2015-11-20)
Tamarix ramosissima is a tree species that is highly resistant to salt and drought. The Tamarix species survives in a broad range of environmental salt levels, and invades major river systems in southwestern United States. It may affect root-associated bacteria
Thomas O J P Elliott et al.
The Journal of infectious diseases, 212(9), 1469-1479 (2015-04-22)
A major barrier to effective tuberculosis control is our limited understanding of risk factors for tuberculosis disease progression. This study examined the role of apoptosis in immunity to tuberculosis. Cell subsets from tuberculosis cases and tuberculin skin test-positive (TST(+)) and
Elaine F da Silva et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 102, 71-74 (2012-12-12)
The formamide (FA)/pyridine (py)/pyridazine (prd) system was investigated by FT-Raman spectroscopy and the results in situ show that FA is preferentially bound to py, as experimentally pointed out by the proton affinity (PA) values of these azabenzenes. Temperature-dependent further investigations
Eric M Farell et al.
BMC research notes, 5, 257-257 (2012-05-26)
While being a standard powerful molecular biology technique, applications of the PCR to the amplification of high GC-rich DNA samples still present challenges which include limited yield and poor specificity of the reaction. Organic solvents, including DMSO and formamide, have
Haywood Dail Laughinghouse et al.
PloS one, 10(12), e0143795-e0143795 (2015-12-03)
Northern hemisphere rockweeds (Fucus) are thought to have evolved in the North Pacific and then spread to the North Atlantic following the opening of the Bering Strait. They have dispersed and widely speciated in the North Atlantic and its tributary
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