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30107

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Simona Capone et al.
International journal of molecular sciences, 16(10), 23127-23142 (2015-09-26)
Horseradish peroxidase (HRP), conjugated to antibodies and lectins, is widely used in medical diagnostics. Since recombinant production of the enzyme is difficult, HRP isolated from plant is used for these applications. Production in the yeast Pichia pastoris (P. pastoris), the
Chih-Sung Liang et al.
Progress in neuro-psychopharmacology & biological psychiatry, 56, 52-57 (2014-08-26)
The association between cardiovascular reactivity and major depressive disorder (MDD) remains unclear. This study aimed to examine this association via reactive heart rate variability (HRV) in a well-diagnosed first-episode MDD group and a control group. A total of 160 physically
Swapna Upadhyay et al.
Particle and fibre toxicology, 11, 36-36 (2014-12-03)
Studies provide compelling evidences for particulate matter (PM) associated cardiovascular health effects. Elderly individuals, particularly those with preexisting conditions like hypertension are regarded to be vulnerable. Experimental data are warranted to reveal the molecular pathomechanism of PM related cardiovascular impairments
Katelyn T Gause et al.
ACS nano, 9(3), 2433-2444 (2015-02-26)
The development of subunit antigen delivery formulations has become an important research endeavor, especially in cases where a whole cell vaccine approach has significant biosafety issues. Particle-based systems have shown particular efficacy due to their inherent immunogenicity. In some cases
Ying Wang et al.
Diabetes research and clinical practice, 108(1), 55-66 (2015-02-18)
Heart failure (HF) is a major cause of mortality and disability in type 2 diabetes mellitus (T2DM). This study sought to improve the assessment of HF risk in patients with T2DM-a step that would be critical for effective HF screening.
Ercole Tagliamonte et al.
Echocardiography (Mount Kisco, N.Y.), 32(3), 516-521 (2014-07-22)
Ranolazine reduces the Na-dependent calcium overload via inhibition of the late sodium current, improving diastolic tone and oxygen handling during myocardial ischemia. In patients with angina, evidence of myocardial ischemia, but no obstructive coronary artery disease (CAD), abnormal coronary autoregulation
Chang Sun Sim et al.
Yonsei medical journal, 56(1), 235-243 (2014-12-17)
To determine the impact of noise on heart rate variability (HRV) in men, with a focus on the noise type rather than on noise intensity. Forty college-going male volunteers were enrolled in this study and were randomly divided into four
Fabiana D M Siman et al.
Journal of cardiovascular pharmacology, 65(1), 28-38 (2014-08-28)
Ouabain occurs in nanomolar concentrations in myocardial infarction and heart failure (HF). However, the effects of ouabain in vascular function in HF conditions were not investigated yet. Therefore, we analyzed the effects of acute administration of 3 nM ouabain in
Bo Tian et al.
Journal of materials science. Materials in medicine, 25(9), 2059-2068 (2014-05-27)
In order to improve the biocompatibility of metallic implants, bioactive components are often used as coatings so that a real bond with the surrounding bone tissue can be formed. We prepared ethyl cellulose/carbonated hydroxyapatite composite coatings (ECHCs) on Ti6Al4V substrates
Sheila Pestana Passos et al.
The journal of adhesive dentistry, 15(5), 461-466 (2013-04-18)
To evaluate the microtensile bond strength (MTBS) of ceramic cemented to dentin varying the resin cement and ceramic shades. Two VITA VM7 ceramic shades (Base Dentine 0M1 and Base Dentine 5M3) were used. A spectrophotometer was used to determine the
Luca D'Alessio et al.
Nature communications, 6, 8336-8336 (2015-10-02)
Realizing topological insulators is of great current interest because of their remarkable properties and possible future applications. There are recent proposals based on Floquet analyses that one can generate topologically non-trivial insulators by periodically driving topologically trivial ones. Here we
Ranjith Ramasamy et al.
Fertility and sterility, 104(2), 286-291 (2015-05-10)
To investigate the genetic cause of nonobstructive azoospermia (NOA) in a consanguineous Turkish family through homozygosity mapping followed by targeted exon/whole-exome sequencing to identify genetic variations. Whole-exome sequencing (WES). Research laboratory. Two siblings in a consanguineous family with NOA. Validating
Daisuke Sueta et al.
American journal of hypertension, 27(12), 1464-1471 (2014-05-30)
Accumulating evidence on blood pressure (BP) reduction with various angiotensin II receptor blockers (ARBs) show that the magnitudes and durations of BP control differ across ARBs. However, the mechanism of ARBs is unknown. This work was undertaken to compare telmisartan
Donatello Castellana et al.
PLoS biology, 12(12), e1002002-e1002002 (2014-12-24)
Skin epithelial stem cells operate within a complex signaling milieu that orchestrates their lifetime regenerative properties. The question of whether and how immune cells impact on these stem cells within their niche is not well understood. Here we show that
Neha Chauhan et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(10), E1077-E1085 (2015-02-26)
Cell growth and division requires the precise duplication of cellular DNA content but also of membranes and organelles. Knowledge about the cell-cycle-dependent regulation of membrane and storage lipid homeostasis is only rudimentary. Previous work from our laboratory has shown that
Zhu-Ming Zhang et al.
Journal of cardiac failure, 21(4), 307-312 (2015-01-15)
We evaluated the risk of incident heart failure (HF) associated with various categories of ventricular conduction defects (VCDs) and examined the impact of QRS duration on the risk of HF. This analysis included 14,478 participants from the Atherosclerosis Risk in
Alberto Palazzuoli et al.
Cardiorenal medicine, 4(3-4), 257-268 (2015-03-05)
Cardiorenal syndrome (CRS) is associated with increased cardiovascular morbidity and mortality; still, its biomarker pattern has been poorly evaluated so far. The aim of this study was to measure the inflammatory activation, neurohormonal status and kidney and myocardial damage in
Alban Redheuil et al.
Journal of the American College of Cardiology, 64(24), 2619-2629 (2014-12-20)
The predictive value of ascending aortic distensibility (AAD) for mortality and hard cardiovascular disease (CVD) events has not been fully established. This study sought to assess the utility of AAD to predict mortality and incident CVD events beyond conventional risk
Kyung Hoon Kim et al.
Small (Weinheim an der Bergstrasse, Germany), 11(46), 6215-6224 (2015-10-21)
Tracking and monitoring the intracellular behavior of mRNA is of paramount importance for understanding real-time gene expression in cell biology. To detect specific mRNA sequences, molecular beacons (MBs) have been widely employed as sensing probes. Although numerous strategies for MB
E M Caravati
The American journal of emergency medicine, 6(2), 143-150 (1988-03-01)
Significant local and systemic toxicity may occur from hydrofluoric acid by all routes of exposure. Prompt decontamination by removal from the source and copious irrigation of eyes and skin are essential to reduce morbidity and mortality. Ingestion of small amounts
Yuanqin Yin et al.
Cell cycle (Georgetown, Tex.), 13(17), 2707-2722 (2014-12-09)
Tetraspanin CD151 interacts with laminin-binding integrins (i.e., α3β1, α6β1 and α6β4) and other cell surface molecules to control diverse cellular and physiological processes, ranging from cell adhesion, migration and survival to tissue architecture and homeostasis. Here, we report a novel
Pedro Henrique Corazza et al.
The journal of adhesive dentistry, 15(5), 473-479 (2013-04-18)
To evaluate the effect of post-silanization heat treatment of a silane agent and rinsing with hot water of silanized CAD/CAM feldspathic ceramic surfaces on the microtensile bond strength between resin cement and the ceramic, before and after mechanical cycling. Blocks
Simon Klüpfel et al.
The Journal of chemical physics, 137(12), 124102-124102 (2012-10-02)
Self-consistent calculations using the Perdew-Zunger self-interaction correction (PZ-SIC) to local density and gradient dependent energy functionals are presented for the binding energy and equilibrium geometry of small molecules as well as energy barriers of reactions. The effect of the correction
Andrea L Woodhead et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 154, 185-192 (2015-11-03)
Prior to the 19th century the use of purple dyes for textile coloration was expensive and usually limited to royalty. The discovery of several synthetic purple dyes during the 19th century made the production of purple textiles more affordable and
Min Kyoung Kim et al.
Cytotherapy, 17(3), 301-309 (2015-02-11)
Wound healing remains a principal challenge in modern medical science. Chorion-dervied stem cells (CDSCs), isolated from human placenta, have largely been overlooked, and few studies on their potential in wound healing have been conducted. In this study, we investigated the
Matthew Strausburg et al.
Dermatitis : contact, atopic, occupational, drug, 23(5), 231-236 (2012-09-27)
Exposure to hydrofluoric acid can cause severe skin damage via both corrosive and chemical means. Dermatologists should be aware of the various clinical presentations and knowledgeable of how to manage such patients. A case of a man with exposure of
Sol M Rodríguez-Colón et al.
Sleep medicine, 16(1), 67-72 (2015-01-04)
To investigate the effects of objectively measured habitual sleep patterns on cardiac autonomic modulation (CAM) in a population-based sample of adolescents. We used data from 421 adolescents who completed the follow-up examination in the Penn State Children Cohort study. CAM
Xin-gang Wang et al.
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 29(4), 371-374 (2013-12-20)
Hydrofluoric acid (HF) is one of the most common inorganic acids used widely in industrial circle. HF not only causes cutaneous burn, but also induces systemic toxicity by its unique injury mechanism. Accurate and timely diagnosis and treatment are critical
Zheng Tian et al.
Langmuir : the ACS journal of surfaces and colloids, 30(41), 12411-12420 (2014-09-25)
Carbon films with interdigitated bimodal three-dimensionally ordered mesoporosity (ib3DOm) are realized by a scalable nanoreplication process that removes the common need plaguing hard-templating strategies for multistep prefabrication of porous sacrificial templates. Specifically, evaporation-induced convective codeposition of size-tunable (ca. 20-50 nm)
Elena Hilario et al.
PloS one, 10(12), e0143193-e0143193 (2015-12-04)
Genotyping by sequencing (GBS) is a restriction enzyme based targeted approach developed to reduce the genome complexity and discover genetic markers when a priori sequence information is unavailable. Sufficient coverage at each locus is essential to distinguish heterozygous from homozygous
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