Showing 1-30 of 94 results for "30873"
Determination of anthraquinones in rhubarb roots, dock flowers and senna leaves by normal-phase high performance liquid chromatography.
Djozan DJ and Assadi Y
Talanta, 42(6), 861-865 (1995)
A Marechal et al.
Journal of chromatography. A, 1365, 140-147 (2014-09-25)
This paper presents a photografting process of monolithic silica capillary columns based on the ene-thiol click chemistry. This study is performed on a "generic" vinyl-functionalized silica monolith (Hmin 6±1μm). The photoclick reaction is investigated using different thiol monomers (octadecanethiol, cysteine...
Xian-Feng Zhong et al.
Molecular medicine reports, 5(5), 1261-1266 (2012-02-22)
Endothelial cell injury caused by reactive oxygen species (ROS) plays a critical role in the pathogenesis of atherosclerosis. Therefore, phytochemicals or antioxidants that inhibit the production of ROS have clinical value for the treatment of atherosclerosis. Rhein is one of...
Ahmad Aqel et al.
Journal of chromatographic science, 52(3), 201-210 (2013-02-21)
This paper describes the comprehensive fabrication of monolithic materials for use as stationary phases in capillary liquid chromatography. Several columns were synthesized in the confines of 320 µm i.d. fused-silica capillaries by single-step in situ copolymerization of benzyl methacrylate and...
Maria G Kouskoura et al.
Journal of pharmaceutical and biomedical analysis, 100, 94-102 (2014-08-26)
One of the most challenging aims in modern analytical chemistry and pharmaceutical analysis is to create models for drugs' behavior based on simulation experiments. Since drugs' effects are closely related to their molecular properties, numerous characteristics of drugs are used...
Venkata Krishna Bayineni et al.
Biochemical and biophysical research communications, 453(4), 784-786 (2014-12-03)
An autobiographic method based on the thin layer chromatogram was developed by using the chemical system that comprises p-Nitrophenyl butyrate and bromothymol blue for detecting the lipase inhibitor. Lipase inhibitory zones were visualized as blue spots against the greenish yellow...
Qing Lan et al.
Carcinogenesis, 36(1), 160-167 (2014-11-14)
Formaldehyde (FA) is an economically important industrial chemical to which millions of people worldwide are exposed environmentally and occupationally. Recently, the International Agency for Cancer Research concluded that there is sufficient evidence that FA causes leukemia, particularly myeloid leukemia. To...
Kévin Cocq et al.
Chemical record (New York, N.Y.), 15(1), 347-361 (2015-01-30)
Beyond rigorous inspection of the literature, selected comments and drawings from the Nozoe Autograph Books show how concepts and targets of the chemistry of today already existed 40 years ago. This is illustrated for the chemistry of carbo-mers, which was...
Takahiro Yamauchi et al.
BMC cancer, 14, 547-547 (2014-07-30)
Nine-beta-D-arabinofuranosylguanine (ara-G), an active metabolite of nelarabine, enters leukemic cells through human Equilibrative Nucleoside Transporter 1, and is then phosphorylated to an intracellular active metabolite ara-G triphosphate (ara-GTP) by both cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. Ara-GTP is subsequently...
Yanfeng Zhou et al.
PloS one, 9(10), e110466-e110466 (2014-10-22)
The prevalence of childhood leukemia is increasing rapidly all over the world. However, studies on maternal benzene exposure during pregnancy and childhood acute lymphoblastic leukemia (ALL) have not been systematically assessed. Therefore, we performed a meta-analysis to investigate the association...
Shankha S Acharyya et al.
ACS applied materials & interfaces, 6(16), 14451-14459 (2014-08-02)
Three-dimensional (3D) raspberry-like CuCr2O4 spinel nanoparticles were prepared hydrothermally in the presence of cationic surfactant, cetyltrimethylammonium bromide (CTAB). Detailed characterization of the material was carried out by X-ray diffraction (XRD), inductively coupled plasma-atomic emission spectroscopy (ICP-AES), X-ray photoelectron spectroscopy (XPS)...
Li Wang et al.
Biochemical pharmacology, 86(7), 991-996 (2013-08-27)
Rhein, a major metabolite of the prodrug diacerein and a major component of the medicinal herb Rheum sp., is used for its beneficial effects in a variety of clinical applications including the treatment of osteoarthritis and diabetic nephropathy. The physicochemical...
Yunbin Xiao et al.
International journal of nanomedicine, 10, 1155-1172 (2015-02-25)
Magnetic resonance imaging (MRI) contrast agents based on chitosan derivatives have great potential for diagnosing diseases. However, stable tumor-targeted MRI contrast agents using micelles prepared from high molecular weight chitosan derivatives are seldom reported. In this study, we developed a...
Qiqing Chen et al.
The Science of the total environment, 496, 453-460 (2014-08-12)
The potential transfer of fullerene aqueous suspension (nC₆₀) associated contaminants in vivo is one of the most significant and currently not well-understood environmental risks. In this study, the carrier function of nC₆₀ for ibuprofen (IBU) was examined through whole-body and...
Emma Oakton et al.
Dalton transactions (Cambridge, England : 2003), 43(40), 15138-15142 (2014-09-03)
Herein, we report the preparation of small and narrowly distributed (2.1 ± 0.5 nm) Ag nanoparticles supported on passivated silica, where the surface OH groups are replaced by OSiMe3 functionalities. This synthetic method involves the grafting of silver(I) bis(trimethylsilyl)amide ([AgN(SiMe3)2]4)...
Hyun-Jeong Eom et al.
Environmental science & technology, 48(14), 8143-8151 (2014-05-23)
In this study, we investigated the toxic effects of benzene to the nematode Caenorhabditis elegans in an integrative manner, using computational behavior and toxicogenomics analyses, along with survival and reproduction. Benzene exposure led to changes in locomotive behavior and reproduction...
Jing Liu et al.
Diabetes, 62(11), 3927-3935 (2013-08-08)
Rhein, an anthraquinone compound isolated from rhubarb, has been shown to improve glucose metabolism disorders in diabetic mice. The mechanism underlying the protective effect of rhein, however, remains unknown. Here, we demonstrate that rhein can protect the pancreatic β-cells against...
Ye-Fei Yuan et al.
Natural product communications, 7(2), 207-210 (2012-04-06)
To improve the anti-tumor effects of rhein and aloe-emodin, a rhein-aloe-emodin hybrid molecule (RH-AE) was synthesized from rhein and aloe-emodin in the presence of dicyclohexylcarbodiimide (DCC) and 4-dimethylaminopyridine (DMAP). Chemical and spectroscopic methods, such as 1H and 13C NMR spectroscopy...
Xu Jing et al.
Journal of the American Chemical Society, 137(11), 3967-3974 (2015-03-05)
The design of artificial systems that mimic highly evolved and finely tuned natural photosynthetic systems is a subject of intensive research. We report herein a new approach to constructing supramolecular systems for the photocatalytic generation of hydrogen from water by...
Baljinder Singh et al.
Journal of ethnopharmacology, 141(1), 469-473 (2012-03-28)
Leaves of Cassia alata (family: Caesalpiniaceae) are ethnomedically claimed as anti-asthmatic. In the current study we aimed to investigate the anti-allergic activities of hydro-methanolic extract of Cassia alata (Linn.) and its constituents rhein and kaempferol on triple antigen/sheep serum-induced mast-cell...
L Allmendinger et al.
Journal of labelled compounds & radiopharmaceuticals, 57(13), 721-724 (2014-11-11)
Deuterium-labelled indatraline was synthesized in high efficiency employing a Friedel-Crafts alkylation of [(2)H6]benzene with (E)-3-(3,4-dichlorophenyl)acrylic acid as a key step. The desired labelling of the final compound was ascertained in two ways, by incorporation of [(2)H6]benzene in the target molecule...
Yuanhong Shan et al.
Journal of chromatography. A, 1375, 101-109 (2014-12-17)
To develop a novel hybrid monolithic column based on pentafluorobenzyl imidazolium bromide ionic liquid, a new ionic liquid monomer was synthesized from 1-vinylimidazole and pentafluorobenzyl bromide. By employing a facile one-step copolymerization of polyhedral-oligomeric-silsesquioxane-type (POSS) cross-linking agent and the home-made...
Yuying Wang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(2), 212-217 (2012-06-29)
To establish a quality evaluation method, quantitative analysis of multi-component with a single-marker (QAMS) to determine the contents of four rhubarb anthraquinones in Sanhuang tablets. Emodin was used as the internal reference substance, the relative correlation factors (RCF) of rhein...
Shigeo Hayashi et al.
Journal of enzyme inhibition and medicinal chemistry, 29(6), 846-867 (2014-02-13)
Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional NSAIDs exhibit serious side-effects such as gastrointestinal damage...
Simultaneous determination of baicalin, rhein and berberine in rat plasma by column-switching high-performance liquid chromatography.
Yi L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 838(1), 50-55 (2006)
F Groeber et al.
Pharmaceutical research, 32(5), 1845-1854 (2014-12-04)
Reconstructed human epidermis (RHE) is standardly used for the risk assessment of chemical compounds. However, analysis is dependent on invasive methods such as histological processing or 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) staining. As an alternative, we have developed a non-destructive technology to...
Andrei Ponta et al.
Journal of drug targeting, 22(7), 619-628 (2014-04-29)
Nanoparticles are widely used as drug carriers for controlled, tumor-targeted delivery of various anticancer agents that have biopharmaceutical limitations such as water solubility and tissue permeability. Growing evidence suggests that nanoparticles not only reduce toxic side effects of anticancer drugs...
Ping Huang et al.
Bioanalysis, 4(10), 1205-1213 (2012-06-02)
Dahuang Huanglian Xiexin Decoction (DHXD) is a classical formula in traditional Chinese medicines. In this study, a novel UPLC-MS/MS method was developed for the simultaneous quantification of rhein, emodin, berberine and baicalin, the major bioactive compounds of DHXD in rat...
Hyeong Jun Lim et al.
Physical chemistry chemical physics : PCCP, 16(33), 17466-17472 (2014-07-16)
The Hansen solubility parameters (HSPs) of as-produced multi-walled carbon nanotubes (APMWCNTs) were determined by means of the inverse gas chromatography (IGC) technique. Due to non-homogeneous surfaces of the APMWCNTs arising from defects and impurities, it was necessary to establish adequate...
Maryam Maghsoodi et al.
Drug development and industrial pharmacy, 40(11), 1468-1475 (2013-08-14)
Spherical crystallization is a process of formation of agglomerates of crystals held together by binder liquid. This research focused on understanding the effect of type of solvents used as binder liquid on the agglomeration of crystals. Carbamazepine and ethanol/water were...

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