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Alicja Piasecka et al.
Journal of applied genetics, 56(1), 115-121 (2014-09-04)
The p53 transcription factor is a key tumor suppressor and a central regulator of the stress response, which has been a subject of intense research for over 30 years. Recently, a zebrafish line which carries splice site mutation (G>T) in intron...
Julia Müller et al.
Basic research in cardiology, 109(6), 440-440 (2014-09-23)
Interleukin-6 (IL-6) is a multifunctional cytokine that orchestrates the immune response to a wide variety of pathophysiologic challenges but also contributes to tissue homeostasis. Furthermore, IL-6 is elevated in patients with acute myocardial infarction. Hyaluronan (HA) is an extracellular carbohydrate...
Daniela Gradinaru et al.
Toxicology letters, 213(3), 316-324 (2012-08-01)
The present work reports data regarding effects of an induced oxidative stress on the mainly expressed isoforms of UDP-glucuronosyltransferases (UGTs) in the brain. UGT1A6 and UGT1A7 expression and enzymatic activities toward the 1-naphthol were analyzed in rat cultured astrocytes following...
Fanfan Wang et al.
Environmental pollution (Barking, Essex : 1987), 196, 371-378 (2014-12-03)
The abiotic transformation of nanomaterials in the natural environment can significantly affect their fate,transport, and effects. We observed that the adsorption affinities of graphene oxide nanoparticles(GONPs) for both phenanthrene and 1-naphthol were profoundly enhanced in the presence of sulfide, an...
Arjyabaran Sinha et al.
Chemistry, an Asian journal, 8(4), 786-791 (2013-02-13)
Graphene is a 2D sp(2)-hybridized carbon sheet and an ideal material for the adsorption-based separation of organic pollutants. However, such potential applications of graphene are largely limited, owing to their poor solubility and extensive aggregation properties through graphene-graphene interactions. Herein...
Yu Fen Zheng et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 68, 117-127 (2014-03-19)
We evaluated the potential of BST204, a purified dry extract of ginseng, to inhibit or induce human liver cytochrome P450 enzymes (CYPs) and UDP-glucuronosyltransferases (UGTs) in vitro to assess its safety. In vitro drug interactions of four bioactive ginsenosides of...
Eu Jin Choi et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 72, 13-19 (2014-07-06)
In this study, we evaluated inhibitory potentials of popularly-consumed berries (bilberry, blueberry, cranberry, elderberry, and raspberry ketones) as herbal supplements on UGT1A1, UGT1A4, UGT1A6, UGT1A9, and UGT2B7 in vitro. We also investigated the potential herb-drug interaction via UGT1A1 inhibition by...
Hyojung Park et al.
Antioxidants & redox signaling, 22(1), 63-77 (2014-07-31)
Lipopolysaccharide (LPS) is considered a prominent pathogenic factor in inflammatory bone diseases. LPS challenge contributes to the production of reactive oxygen species (ROS) in diverse inflammatory diseases. However, its mechanism remains to be clarified in bone. Thus, we investigated the...
Direct determination of 1-naphthol in human urine by coupled-column liquid chromatography with fluorescence detection.
Sancho JV, et al.
Chromatographia, 58(9-10), 565- 569 (2003)
Jennifer J Bara et al.
Tissue engineering. Part A, 20(1-2), 147-159 (2013-07-31)
Osteochondral tissue repair requires formation of vascularized bone and avascular cartilage. Mesenchymal stem cells stimulate angiogenesis both in vitro and in vivo but it is not known if these proangiogenic properties change as a result of chondrogenic or osteogenic differentiation....
Gang Liang et al.
Biosensors & bioelectronics, 45, 46-51 (2013-03-05)
A highly sensitive, reusable G-rich DNA sensor was reported for the detection of α-naphthol by electrochemical impedance spectroscopy (EIS). Specifically, a single-stranded G-rich DNA was self-assembled on the electrode and transformed into K(+)-stabilized G-quadruplex, which could catalyze H2O2-mediated oxidation of...
Ejaz Ahmad et al.
PloS one, 7(6), e38372-e38372 (2012-06-12)
Structural changes in human serum albumin (HSA) induced by the pollutants 1-naphthol, 2-naphthol and 8-quinolinol were analyzed by circular dichroism, fluorescence spectroscopy and dynamic light scattering. The alteration in protein conformational stability was determined by helical content induction (from 55...
Meng Zhang et al.
Environmental pollution (Barking, Essex : 1987), 195, 84-90 (2014-09-10)
Biochars from nitrogen-rich biomaterials (i.e., α-amylase, chitin and zein) were produced at different temperatures (i.e. 170, 250, 350 and 450 °C) and characterized, and their sorption for phenanthrene, naphthalene and 1-naphthol was investigated. The organic carbon content normalized-sorption coefficient (Koc) of...
María Asensio-Ramos et al.
Electrophoresis, 33(9-10), 1449-1457 (2012-06-01)
In this work, the use of the ionic liquid (IL) 1,3-dipentylimidazolium hexafluorophosphate ([PPIm][PF₆]) as an alternative extractant for IL dispersive liquid-liquid microextraction (IL-DLLME) of a group of pesticides and metabolites (2-aminobenzimidazole, carbendazim/benomyl, thiabendazole, fuberidazole, carbaryl, 1-naphthol, and triazophos) from soils...
Abhishek Chauhan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 110-118 (2015-02-11)
Nano-sized molecularly imprinted polymer (nMIP) was synthesized through precipitation polymerization method and used it as solid phase extraction (SPE) sorbent for the selective and simultaneous extraction of hydroxylated metabolites of polycyclic aromatic hydrocarbons (PAHs) from urine followed by ultra-high performance...
Tanveer Ahmed et al.
Environmental toxicology and chemistry, 31(10), 2201-2209 (2012-07-05)
The binding interactions of 1-naphthol with effluent and whole natural dissolved organic matter (DOM) samples were analyzed by using a fluorescence quenching technique. Nonfractionated DOM samples from Lake Biwa (Japan), creek water, treated sewage effluents, and an extracted Lake Biwa...
Sandy Fillet et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(37), 15372-15377 (2011-08-31)
Members of the IclR family control bacterial genes involved in a number of physiological processes. The IclR-family member TtgV crystallizes as a tetramer, with each TtgV monomer consisting of two domains--a DNA binding domain and an effector recognition domain, which...
Raifish E Mendoza-Villarroel et al.
Biology of reproduction, 91(1), 26-26 (2014-06-06)
Testosterone production is dependent on cholesterol transport within the mitochondrial matrix, an essential step mediated by a protein complex containing the steroidogenic acute regulatory (STAR) protein. In steroidogenic Leydig cells, Star expression is hormonally regulated and involves several transcription factors....
Johannes Keller et al.
Nature communications, 5, 5215-5215 (2014-10-22)
The hormone calcitonin (CT) is primarily known for its pharmacologic action as an inhibitor of bone resorption, yet CT-deficient mice display increased bone formation. These findings raised the question about the underlying cellular and molecular mechanism of CT action. Here...
Leandra Naira Z Ramalho et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 74, 270-278 (2014-12-03)
Rosmarinic acid (RosmA) demonstrates antioxidant and anti-inflammatory properties. We investigated the effect of RosmA on liver ischemia/reperfusion injury. Rats were submitted to 60 min of ischemia plus saline or RosmA treatment (150 mg/kg BW intraperitoneally) followed by 6 h of reperfusion. Hepatocellular injury...
Kristen W Smith et al.
Journal of exposure science & environmental epidemiology, 22(1), 35-45 (2011-11-03)
There is a potential for widespread occupational exposure to jet fuel among military and civilian personnel. Urinary metabolites of naphthalene have been suggested for use as short-term biomarkers of exposure to jet fuel (jet propulsion fuel 8 (JP8)). In this...
Yusuke Tanigawa et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 28(9), 921-924 (2012-09-15)
Open-tubular capillary chromatography using a ternary solvent mixture consisting of a water-hydrophilic-hydrophobic organic solvent as a carrier solution has been developed. When the ternary carrier solution is fed into the capillary tube, the carrier solvents are radially distributed and generate...
Taro Kariya et al.
Journal of cellular biochemistry, 116(1), 12-21 (2014-06-07)
Orthodontic tooth movement induces alveolar bone resorption and formation by mechanical stimuli. Force exerted on the traction side promotes bone formation. Adenosine triphosphate (ATP) is one of the key mediators that respond to bone cells by mechanical stimuli. However, the...
Jianwen Bai et al.
Innate immunity, 21(1), 42-54 (2014-01-07)
Respiratory burst function of neutrophils is thought to play a pivotal role in the development of pathologies such as indirect (extra-pulmonary) acute lung injury (iALI), as well as sepsis. The current study was conducted to determine the effect of an...
Iu E Kolupaev et al.
Prikladnaia biokhimiia i mikrobiologiia, 48(5), 550-556 (2012-10-30)
The influence of salicylic (SaA) and succinic (SuA) acids on the generation of active oxygen forms (AOFs) and the heat resistance of wheat (Triticum aestivum L.) coleoptiles has been studied. The treatment of coleoptiles with 10 microM SaA or SuA...
Srinivasan Suresh et al.
The Analyst, 137(17), 4086-4092 (2012-07-13)
An amperometric immunosensor for the specific detection of Ricinus communis is reported. Screen printed electrodes (SPEs) were modified with gold nanoparticles (GNPs) loaded multiwalled carbon nanotubes (MWCNTs)-chitosan (Ch) film. The ratio of MWCNT and GNP was optimised to get best...
Zaiming Chen et al.
Environmental science & technology, 46(22), 12476-12483 (2012-11-06)
The bisolute sorption and thermodynamic behavior of organic pollutants on low temperature biochars (LTB) at 300 °C and high temperature biochars (HTB) at 700 °C were determined to elucidate sorptive properties of biochar changed with pyrolytic temperatures. The structural characteristics...
Jizheng Dang et al.
Bioorganic & medicinal chemistry letters, 23(3), 646-649 (2012-12-27)
At pH from 5.5 to 7.6, absorptivity of 4-nitro-1-naphthol at 450 nm is over 2.1-fold of that of para-nitrophenol at 405 nm and over 9.6-fold of that of ortho-nitrophenol at 415 nm. On 4-nitro-1-naphthyl-β-D-galactopyranoside at pH 7.4, catalytic efficiency of...
Shitong Yang et al.
The Science of the total environment, 420, 214-221 (2012-02-15)
The increasing exploitation of multi-walled carbon nanotubes (MWCNTs) into many industrial processes has raised considerable concerns as they are likely to be released into the environment. The interactions of the pollutants in water with discharged MWNCTs will further influence the...
Ondrej Zitka et al.
Electrophoresis, 32(22), 3207-3220 (2011-10-21)
Guanosine derivatives are important for diagnosis of oxidative DNA damage including 8-hydroxy-2'-deoxyguanosine (8-OHdG) as one of the most abundant products of DNA oxidation. This compound is commonly determined in urine, which makes 8-OHdG a good non-invasive marker of oxidation stress....
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