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Yaqin Jiang et al.
Scientific reports, 5, 16372-16372 (2015-11-10)
Due to their relatively high compatibility with specific photonic structures, strong light-matter interactions and unique nonlinear optical response, two-dimensional (2D) materials, such as graphene and transition metal dichalcogenides, are attractive for ultrafast photonics applications. Here, we fabricate MoS2/graphene nanocomposites by...
Sara Bobone et al.
Biopolymers, 104(5), 521-532 (2015-05-15)
Total syntheses and complete characterizations of singly substituted PheCN -based analogs of alamethicin AlaP, which is active on model and natural membranes, and the TM peptide, which inserts in a transmembrane orientation in lipid bilayers, are reported. The syntheses of...
Feng Wang et al.
Nature communications, 6, 6668-6668 (2015-03-27)
Transition metal fluorides are an appealing alternative to conventional intercalation compounds for use as cathodes in next-generation lithium batteries due to their extremely high capacity (3-4 times greater than the current state-of-the-art). However, issues related to reversibility, energy efficiency and...
Eric Allcorn et al.
Physical chemistry chemical physics : PCCP, 17(43), 28837-28843 (2015-10-10)
The diffusion coefficient of lithium is an important parameter in determining the rate capability of an electrode and its ability to deliver high power output. Galvanostatic intermittent titration technique (GITT) is a quick electrochemical method to determine diffusion coefficients in...
C J Bagley et al.
International journal of peptide and protein research, 36(4), 356-361 (1990-10-01)
Insulin-like growth factor I (IGF-I), a protein of 70 amino acid residues and 3 cystine bridges, has been synthesized by two solid phase Boc methods. The first method used N-methylpyrrolidinone as the solvent with single coupling cycles while the second...
Nitin Wasantrao Fadnavis et al.
Archives of biochemistry and biophysics, 433(2), 454-465 (2004-12-08)
Effects of cosolvent concentration on activity of fire fly luciferase, alpha-chymotrypsin, and alcohol dehydrogenase from baker's yeast (Saccharomyces cerevisiae) have been studied for several solvents with varying hydrophobicities (logP from +1.0 to -1.65) and polarities (dielectric constant from 7.4 to...
Nurit Atar et al.
ACS applied materials & interfaces, 7(22), 12047-12056 (2015-05-07)
In low Earth orbit (LEO), hazards such as atomic oxygen (AO) or electrostatic discharge (ESD) degrade polymeric materials, specifically, the extensively used polyimide (PI) Kapton. We prepared PI-based nanocomposite films that show both AO durability and ESD protection by incorporating...
Maja Šrut et al.
Ecotoxicology (London, England), 24(4), 887-902 (2015-02-24)
Sublethal exposure to environmental genotoxicants may impact genome integrity in affected organisms. It is therefore necessary to develop tools to measure the extent and longevity of genotoxicant-induced DNA damage, and choose appropriate model organisms for biomonitoring. To this end, markers...
Munawar Hussain et al.
Talanta, 147, 1-7 (2015-11-26)
We present a fast, robust and straightforward spin force assisted surface imprinting approach for activated platelets and demonstrate that Heparin induced thrombocytopenia (HIT) platelet aggregation can be measured by this approach. A critical and challenging step in functional assays for...
Giacomo M Di Mauro et al.
Biochimica et biophysica acta. Biomembranes, 1862(9), 183332-183332 (2020-05-04)
Lipid-nanodiscs have been shown to be an exciting innovation as a membrane-mimicking system for studies on membrane proteins by a variety of biophysical techniques, including NMR spectroscopy. Although NMR spectroscopy is unique in enabling the atomic-resolution investigation of dynamic structures...
Paul Lueth et al.
Journal of controlled release : official journal of the Controlled Release Society, 294, 288-297 (2018-12-21)
New therapies are needed to treat chronic bacterial diseases and intracellular pathogens, in particular, are very difficult to manage. The use of nanotherapeutics represents an approach to exploit size and charge of biological membranes to overcome barriers for treatment of...
Haluk Yuzugullu et al.
Nature communications, 6, 8501-8501 (2015-10-08)
The tumour suppressor PTEN, which antagonizes PI3K signalling, is frequently inactivated in haematologic malignancies. In mice, deletion of PTEN in haematopoietic stem cells (HSCs) causes perturbed haematopoiesis, myeloproliferative neoplasia (MPN) and leukaemia. Although the roles of the PI3K isoforms have...
Peter Akrill et al.
Toxicology letters, 134(1-3), 265-269 (2002-08-23)
N-methyl pyrrolidone (NMP) is a substance widely used for its strong and selective solvent capacity. The strong potential NMP has for skin absorption makes biological monitoring ideal for exposure assessment. This study looked at brief exposures to NMP in aqueous...
Weiwei Sun et al.
Nanoscale, 7(31), 13173-13180 (2015-07-17)
Control over one-dimensional growth of spinel-type LiMn2O4 nanowires is challenging in the area of materials science due to their cubic crystal structure. The current strategy is to use a self-support template to fabricate LiMn2O4 nanowires, which is time-consuming and limits...
Hoon Kim et al.
Nature communications, 6, 7278-7278 (2015-06-13)
Elemental sulfur is one of the most attractive cathode active materials in lithium batteries because of its high theoretical specific capacity. Despite the positive aspect, lithium-sulfur batteries have suffered from severe capacity fading and limited rate capability. Here we report...
Stefanie Schrauwen et al.
Gynecologic oncology, 138(1), 165-173 (2015-05-03)
Endometrial carcinoma (EC) is the most common gynecological cancer in the Western World. Treatment options are limited for advanced and recurrent disease. Therefore, new treatment options are necessary. Inhibition of the PI3K/AKT/mTOR and/or the Ras/Raf/MEK pathways is suggested to be...
Settimio Pacelli et al.
International journal of biological macromolecules, 72, 1335-1342 (2014-12-03)
In this work, a natural polysaccharide gellan gum (GG) has been modified with methacrylic groups (GG-MA) and combined with polyethylene glycol dimethacrylate (PEG-DMA) in order to create novel injectable hydrogels that can be easily delivered through a needle and photocross-linked...
Leyi Zhao et al.
ChemSusChem, 10(17), 3409-3418 (2017-08-02)
A highly crystalline graphite powder was prepared from the low temperature (800-1000 °C) graphitization of renewable hard carbon precursors using a magnesium catalyst. The resulting graphite particles are composed of Voronoi-tessellated regions comprising irregular sheets; each Voronoi-tessellated region having a small...
Sethuraman Sathyamoorthi et al.
Waste management (New York, N.Y.), 109, 202-211 (2020-05-16)
A simple and chemical-free recycled carbon-ZnMn2O4 powder (composite) from the spent Zn-carbon batteries is proposed as an effective active material for the supercapacitor. This approach may amplify the economic and environmental benefits of the recycling process. We also synthesized the...
Paul D Fisher et al.
Journal of biomedical materials research. Part A, 103(7), 2365-2373 (2014-11-27)
In situ forming poly(lactic-co-glycolic acid) (PLGA) implants have not been strongly considered for bone applications because of their poor mechanical properties. Here, in situ forming scaffolds containing hydroxyapatite micro- and nanoparticles were characterized to determine their mechanical properties, injectability, and...
Jixin Zhu et al.
Small (Weinheim an der Bergstrasse, Germany), 11(33), 4123-4129 (2015-06-06)
Multifunctional MoS2 @PANI (polyaniline) pseudo-supercapacitor electrodes consisting of MoS2 thin nanosheets and PANI nanoarrays are fabricated via a large-scale approach. The superior capacitance retention is retained up to 91% after 4000 cycles and a high energy density of 106 Wh...
W Guo et al.
Cell death & disease, 5, e1409-e1409 (2014-09-05)
Btk and Etk/BMX are Tec-family non-receptor tyrosine kinases. Btk has previously been reported to be expressed primarily in B cells and has an important role in immune responses and B-cell malignancies. Etk has been shown previously to provide a strong...
David S Hewings et al.
Journal of medicinal chemistry, 54(19), 6761-6770 (2011-08-20)
Histone-lysine acetylation is a vital chromatin post-translational modification involved in the epigenetic regulation of gene transcription. Bromodomains bind acetylated lysines, acting as readers of the histone-acetylation code. Competitive inhibitors of this interaction have antiproliferative and anti-inflammatory properties. With 57 distinct...
P Sivakumar et al.
Ultrasonics sonochemistry, 26, 332-339 (2015-03-10)
LiNi0.5Mn1.5O4 was synthesized as a cathode material for Li-ion batteries by a sonochemical reaction followed by annealing, and was characterized by XRD, SEM, HRTEM and Raman spectroscopy in conjunction with electrochemical measurements. Two samples were prepared by a sonochemical process...
Norisuke Shibuya et al.
Oncology, 88(5), 309-319 (2015-01-17)
Glycolysis and the pentose phosphate pathway (PPP) are preferentially activated in cancer cells. Accumulating evidence indicated the significance of the altered glucose metabolism in cancer, but the implication for oncotherapy remains unclear. Here we report that the synthesis of glycolytic...
Ryo Matsumoto et al.
Scientific reports, 5, 12884-12884 (2015-08-11)
Peptides, especially intracellular functional peptides that can play a particular role inside a cell, have attracted attention as promising materials to control cell fate. However, hydrophilic materials like peptides are difficult for cells to internalize. Therefore, the screening and design...
Junyoung Choi et al.
Nanomaterials (Basel, Switzerland), 10(10) (2020-10-11)
To inhibit Li-dendrite growth on lithium (Li)-metal electrodes, which causes capacity deterioration and safety issues in Li-ion batteries, we prepared a porous polyimide (PI) sponge using a solution-processable high internal-phase emulsion technique with a water-soluble PI precursor solution; the process...
Kunio Wada et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 786-788, 114-119 (2015-07-28)
As part of the Japanese Center for the Validation of Alternative Methods (JaCVAM) international validation study of in vivo rat alkaline comet assays, we examined cadmium chloride, chloroform, and D,L-menthol under blind conditions as coded chemicals in the liver and...
1-Methyl-2-pyrrolidinone: A well-adapted solvent in the benzothiazoles synthesis.
Brembilla A, et al.
Synthetic Communications, 20(21), 3379-3384 (1990)
Javed Iqbal et al.
Polymers, 12(12) (2020-12-03)
In this study, silver (Ag) and cobalt oxide (Co3O4) decorated polyaniline (PANI) fibers were prepared by the combination of in-situ aniline oxidative polymerization and the hydrothermal methodology. The morphology of the prepared Ag/Co3O4@PANI ternary nanocomposite was studied by scanning electron...
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