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Matthew D Dean et al.
Evolution; international journal of organic evolution, 63(1), 20-28 (2008-08-30)
Barriers to gene flow can arise at any stage in the reproductive sequence. Most studies of reproductive isolation focus on premating or postzygotic phenotypes, leaving the importance of differences in fertilization rate overlooked. Two closely related species of house mice...
Irena Kukavica-Ibrulj et al.
Journal of bacteriology, 190(8), 2804-2813 (2007-12-18)
Pseudomonas aeruginosa chronic lung infections are the major cause of morbidity and mortality in cystic fibrosis (CF) patients. The P. aeruginosa strains PAO1 and PA14 were compared with the Liverpool epidemic strain LESB58 to assess in vivo growth, infection kinetics...
Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord
Stem Cells in Regenerative Medicine (2009)
A lung segmental model of chronic Pseudomonas infection in sheep.
Collie D, et al.
PLoS ONE, 8(7) (2013)
Keke Shao et al.
PloS one, 6(9), e24910-e24910 (2011-09-29)
Aptamers are short RNA or DNA oligonucleotides which can bind with different targets. Typically, they are selected from a large number of random DNA sequence libraries. The main strategy to obtain aptamers is systematic evolution of ligands by exponential enrichment...
Leen Vandaele et al.
Veterinary research, 42, 14-14 (2011-02-15)
Bluetongue virus serotype 8 (BTV-8), which caused an epidemic in ruminants in central Western Europe in 2006 and 2007, seems to differ from other bluetongue serotypes in that it can spread transplacentally and has been associated with an increased incidence...
Carla Danussi et al.
Molecular and cellular biology, 28(12), 4026-4039 (2008-04-16)
Lymphatic-vasculature function critically depends on extracellular matrix (ECM) and on its connections with lymphatic endothelial cells (LECs). However, the composition and the architecture of ECM have not been fully taken into consideration in studying the biology and the pathology of...
Eugene Y Kim et al.
Clinical immunology (Orlando, Fla.), 127(1), 98-106 (2008-02-16)
The pathogenesis of T cell-mediated diseases like rheumatoid arthritis (RA) has typically been explained in the context of the Th1-Th2 paradigm: the initiation/propagation by pro-inflammatory cytokines, and downregulation by Th2 cytokines. However, in our study based on the adjuvant-induced arthritis...
Emma M Roberts et al.
The Journal of endocrinology, 202(3), 453-462 (2009-07-07)
The apelinergic system, comprised of apelin and its G protein-coupled receptor (APJ; APLNR as given in MGI Database), is expressed within key regions of the central nervous system associated with arginine vasopressin (AVP) synthesis and release as well as in...
Nicole C Grieder et al.
PloS one, 3(9), e3241-e3241 (2008-09-20)
There is increasing evidence that tissue-specific modifications of basic cellular functions play an important role in development and disease. To identify the functions of COPI coatomer-mediated membrane trafficking in Drosophila development, we were aiming to create loss-of-function mutations in the...
Effect of mineral oil, sunflower oil, and coconut oil on prevention of hair damage
Rele AS & Mohile RB.
Journal of Cosmetic Science, 54(2), 175-192 (2003)
Esther van Dam et al.
Cell metabolism, 31(4), 710-725 (2020-03-21)
High-sugar diets cause thirst, obesity, and metabolic dysregulation, leading to diseases including type 2 diabetes and shortened lifespan. However, the impact of obesity and water imbalance on health and survival is complex and difficult to disentangle. Here, we show that...
Andrea Moriondo et al.
American journal of physiology. Heart and circulatory physiology, 308(3), H193-H205 (2014-12-09)
The mechanism through which the stresses developed in the diaphragmatic tissue during skeletal muscle contraction sustain local lymphatic function was studied in 10 deeply anesthetized, tracheotomized adult Wistar rats whose diaphragm was exposed after thoracotomy. To evaluate the direct effect...
Guangming Wu et al.
PLoS biology, 9(7), e1001099-e1001099 (2011-07-19)
Using the murine model of tyrosinemia type 1 (fumarylacetoacetate hydrolase [FAH] deficiency; FAH⁻/⁻ mice) as a paradigm for orphan disorders, such as hereditary metabolic liver diseases, we evaluated fibroblast-derived FAH⁻/⁻-induced pluripotent stem cells (iPS cells) as targets for gene correction...
Benjamin Grau et al.
Purinergic signalling, 4(4), 357-364 (2008-09-09)
The formation of appropriate connections between neurons and their specific targets is an essential step during development and repair of the nervous system. Growth cones are located at the leading edges of the growing neurites and respond to environmental cues...
Takeshi Itabashi et al.
Nature methods, 6(2), 167-172 (2009-01-20)
Accurate chromosome segregation during meiosis depends on the assembly of a microtubule-based spindle of proper shape and size. Current models for spindle-size control focus on reaction diffusion-based chemical regulation and balance in activities of motor proteins. Although several molecular perturbations...
Lynda K McGinnis et al.
Developmental biology, 327(2), 280-287 (2009-01-03)
Oocyte maturation invokes complex signaling pathways to achieve cytoplasmic and nuclear competencies for fertilization and development. The Src-family kinases FYN, YES and SRC are expressed in mammalian oocytes but their function during oocyte maturation remains an open question. Using chemical...
Study of sensory properties of emollients used in cosmetics and their correlation with physicochemical properties
Parente ME & Solana G
International Journal of Cosmetic Science, 27(6), 354-354 (2005)
Marie-Laure Volvert et al.
BMC pharmacology, 8, 10-10 (2008-06-14)
Lipid-soluble thiamine precursors have a much higher bioavailability than genuine thiamine and therefore are more suitable for therapeutic purposes. Benfotiamine (S-benzoylthiamine O-monophosphate), an amphiphilic S-acyl thiamine derivative, prevents the progression of diabetic complications, probably by increasing tissue levels of thiamine...
Angela Rouyar et al.
PloS one, 6(10), e26443-e26443 (2011-10-27)
In nature the aerial trace of pheromone used by male moths to find a female appears as a train of discontinuous pulses separated by gaps among a complex odorant background constituted of plant volatiles. We investigated the effect of such...
Xuchu Ma et al.
Dalton transactions (Cambridge, England : 2003), (46)(46), 10250-10255 (2009-11-19)
Na(4)Si(4) and Na(4)Ge(4) are ideal chemical precursors for inorganic clathrate structures, clusters, and nanocrystals. The monoclinic Zintl phases, Na(4)Si(4) and Na(4)Ge(4), contain isolated homo-tetrahedranide [Si(4)](4-) and [Ge(4)](4-) clusters surrounded by alkali metal cations. In this study, a simple scalable route...
Petra Kellers et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 64(Pt 8), 719-722 (2008-08-06)
The membrane-bound [NiFe] hydrogenase is a unique metalloprotein that is able to catalyze the reversible oxidation of hydrogen to protons and electrons during a complex reaction cycle. The [NiFe] hydrogenase was isolated from the photosynthetic purple sulfur bacterium Allochromatium vinosum...
The involvement of potassium channel ORK1 in short-term memory and sleep in Drosophila
Zhang X, et al.
Medicine, 96(27) (2017)
Catherine Rouby et al.
International journal of otolaryngology, 2011, 203805-203805 (2011-11-03)
The LCOT is a self-administered test designed to assess olfactory deficits. Altogether, 525 subjects contributed to the validation. Elderly participants were well represented in this sample. In a validation study (study 1), 407 healthy and 17 anosmic volunteers between 15...
Yunlong Zhao et al.
Nature nanotechnology, 14(8), 783-790 (2019-07-03)
New tools for intracellular electrophysiology that push the limits of spatiotemporal resolution while reducing invasiveness could provide a deeper understanding of electrogenic cells and their networks in tissues, and push progress towards human-machine interfaces. Although significant advances have been made...
Elisabetta Sabini et al.
Journal of molecular biology, 378(3), 607-621 (2008-04-02)
Deoxycytidine kinase (dCK) is an essential nucleoside kinase critical for the production of nucleotide precursors for DNA synthesis. This enzyme catalyzes the initial conversion of the nucleosides deoxyadenosine (dA), deoxyguanosine (dG), and deoxycytidine (dC) into their monophosphate forms, with subsequent...
Shai Kaplan et al.
Molecular cell, 29(6), 786-792 (2008-04-01)
Cells respond to signals by regulating gene expression. The relation between the level of input signals and the transcription rate of the gene is called the gene's input function. Because most genes are regulated by more than one signal, the...
Hoyoon Lee et al.
Scientific reports, 8(1), 5467-5467 (2018-04-05)
Extraction of cell-free DNA (cfDNA), which exists at an extremely low concentration in plasma, is a critical process for either targeted-sensing or massive sequencing of DNAs. However, such small amount of DNA cannot be fully obtained without high-speed centrifugation (<20,000 g)....
Tomoko Watanabe et al.
BMC cell biology, 11, 38-38 (2010-06-08)
Lipid droplets (LD) are organelles with an important role in normal metabolism and disease. The lipid content of embryos has a major impact on viability and development. LD in Drosophila embryos and cultured cell lines have been shown to move...
Aromatic hydrocarbons of mineral oil origin in foods: a method for determining the total concentration and first results
Biedermann M, et al.
Journal of Agricultural and Food Chemistry, 57(19), 8711-8721 (2009)
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