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Shitong Yang et al.
The Science of the total environment, 420, 214-221 (2012-02-15)
The increasing exploitation of multi-walled carbon nanotubes (MWCNTs) into many industrial processes has raised considerable concerns as they are likely to be released into the environment. The interactions of the pollutants in water with discharged MWNCTs will further influence the
Sung-Jun Ahn et al.
The American journal of Chinese medicine, 43(4), 715-729 (2015-06-30)
Angelica tenuissima has been traditionally used in oriental medicine for its therapeutic effects in headache, toothache, and flu symptoms. It also exerts anti-inflammatory activity via the inhibition of the expression of cyclooxygenase-2 (COX-2). However, the effect of Angelica tenuissima on
Antonio Torrelo et al.
The American Journal of dermatopathology, 37(7), 517-522 (2015-06-20)
Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE) syndrome is a newly characterized autoinflammatory disorder, caused by mutations in PSMB8. It is characterized by early-onset fevers, accompanied by a widespread, violaceous, and often annular cutaneous eruption. Although the
Ondrej Zitka et al.
Electrophoresis, 32(22), 3207-3220 (2011-10-21)
Guanosine derivatives are important for diagnosis of oxidative DNA damage including 8-hydroxy-2'-deoxyguanosine (8-OHdG) as one of the most abundant products of DNA oxidation. This compound is commonly determined in urine, which makes 8-OHdG a good non-invasive marker of oxidation stress.
Di Yang et al.
Journal of cellular biochemistry, 116(11), 2628-2636 (2015-04-29)
Alteration of methylation status of lysine 27 on histone H3 (H3K27) associates with dramatic changes in gene expression in response to various differentiation signals. Demethylation of H3K27 is controlled by specific histone demethylases including ubiquitously transcribed tetratricopeptide repeat X chromosome
Zhaolei Cui et al.
Acta histochemica, 117(3), 235-242 (2015-03-22)
The enzyme activity of lactate dehydrogenase C4 (LDH-C4, due to tetrameric nature of C-subunit) has been proposed as an important parameter in evaluating sperm motility and semen quality. A novel histochemical staining method for detecting LDH-C4 activity in human spermatozoa
Accurate hydrogen-bonding energies between 1-naphthol and water, methanol and ammonia.
Burgi T, et al
Chemical Physics Letters, 246(3), 291-299 (1995)
Soo Hyeon Bae et al.
Antimicrobial agents and chemotherapy, 58(9), 5036-5046 (2014-06-04)
Macrolactin A (MA) and 7-O-succinyl macrolactin A (SMA), polyene macrolides containing a 24-membered lactone ring, show antibiotic effects superior to those of teicoplanin against vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus. MA and SMA are currently being evaluated as antitumor agents
Zhongshuang Liu et al.
Molecular medicine reports, 12(3), 3508-3514 (2015-06-06)
The present study aimed to analyze the effects of estrogen deficiency on buccal alveolar bone proper and the periodontal ligament in ovariectomized (OVX) rats, compared with rats that had been subjected to sham treatment. Morphological and histological changes in the
Yoshika Suzawa et al.
International journal of molecular sciences, 16(6), 14245-14258 (2015-06-26)
Hydroxyapatite (HA) or calcium carbonate (CaCO3) formed on an organic polymer of agarose gel is a biomaterial that can be used for bone tissue regeneration. However, in critical bone defects, the regeneration capability of these materials is limited. Mesenchymal stem
David Kokel et al.
Nature chemical biology, 2(6), 338-345 (2006-05-16)
Naphthalene (1) and para-dichlorobenzene (PDCB, 2), which are widely used as moth repellents and air fresheners, cause cancer in rodents and are potential human carcinogens. However, their mechanisms of action remain unclear. Here we describe a novel method for delivering
Megumi Shintani et al.
Physical chemistry chemical physics : PCCP, 14(40), 14049-14060 (2012-09-18)
The location, orientation, and dynamics of hydrophobic small molecules in lipid membranes are studied through combined use of solution-state (1)H-NMR and MD simulation. 1-Naphthol and 1-methylnaphthalene were adopted as the small molecules with or without hydrophilic groups. The nuclear Overhauser
Juha Laitinen et al.
Toxicology letters, 213(1), 129-133 (2012-06-20)
During the past decade, more research has focused on firefighters' multiple exposures via multi-route exposure. Multi-route exposure can alter the kinetics of chemicals; this has brought changes to the recommendations on biomonitoring. In addition, the possibility that the chemicals in
Priyanka Sharma et al.
The Analyst, 137(10), 2495-2502 (2012-03-31)
A solid phase extraction micro-cartridge containing a non-polar polystyrene absorbent matrix was coupled with an electrochemical immunoassay analyzer (EIA) and used for the ultra-sensitive detection of the phenyl urea herbicide diuron in real samples. The EIA was fabricated by using
Zhonghua Wang et al.
Journal of proteome research, 14(6), 2583-2593 (2015-05-21)
The toxicities of polycyclic aromatic hydrocarbons (PAHs) have been extensively explored due to their carcinogenic and mutagenic potency; however, little is known about the metabolic responses to chronic environmental PAH exposure among the general population. In the present study, 566
Masayoshi Yamaguchi et al.
Oncology reports, 34(4), 2156-2162 (2015-08-12)
Gentian violet (GV) is a cationic triphenylmethane dye, with potent antifungal and antibacterial activity. We recently reported that in vitro GV suppresses the differentiation of bone resorbing osteoclasts while stimulating the differentiation and activity of bone forming osteoblasts. Breast cancer
B E Pippenger et al.
Osteoarthritis and cartilage, 23(11), 1865-1869 (2015-11-03)
The cellular component of subchondral bone is thought to be responsible for aberrant bone remodeling in osteoarthritis (OA). Direct phenotypical analysis of the cellular compartment is critical to better understand the OA disease process. This study provides proof-of-principle for flow
Ki-Shuk Shim et al.
The American journal of Chinese medicine, 43(5), 1013-1030 (2015-07-25)
The herb Orostachys japonicus has been traditionally used to treat chronic diseases, such as hepatitis, hemorrhoids, and cancer, in Asia. In this study, we investigated the effect of Orostachys japonicus water extract (OJWE) on the receptor activator of nuclear factor-κB
Zhichong Qi et al.
Environmental science & technology, 48(17), 10136-10144 (2014-08-08)
With the increasing production and use of graphene oxide, the environmental implications of this new carbonaceous nanomaterial have received much attention. In this study, we found that the presence of low concentrations of graphene oxide nanoparticles (GONPs) significantly enhanced the
Srinivasan Suresh et al.
The Analyst, 137(17), 4086-4092 (2012-07-13)
An amperometric immunosensor for the specific detection of Ricinus communis is reported. Screen printed electrodes (SPEs) were modified with gold nanoparticles (GNPs) loaded multiwalled carbon nanotubes (MWCNTs)-chitosan (Ch) film. The ratio of MWCNT and GNP was optimised to get best
Zaiming Chen et al.
Environmental science & technology, 46(22), 12476-12483 (2012-11-06)
The bisolute sorption and thermodynamic behavior of organic pollutants on low temperature biochars (LTB) at 300 °C and high temperature biochars (HTB) at 700 °C were determined to elucidate sorptive properties of biochar changed with pyrolytic temperatures. The structural characteristics
Manasa G Garimella et al.
Journal of immunology (Baltimore, Md. : 1950), 195(11), 5136-5148 (2015-11-06)
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammatory synovitis leading to joint destruction and systemic bone loss. The inflammation-induced bone loss is mediated by increased osteoclast formation and function. Current antirheumatic therapies primarily target suppression of inflammatory
Susanne Sievers et al.
Nucleic acids research, 42(14), 9383-9398 (2014-07-19)
The multicopy sRNA LhrC of the intracellular pathogen Listeria monocytogenes has been shown to be induced under infection-relevant conditions, but its physiological role and mechanism of action is not understood. In an attempt to pinpoint the exact terms of LhrC
Maria Pino et al.
Retrovirology, 12, 37-37 (2015-05-08)
Myeloid cells are key players in the recognition and response of the host against invading viruses. Paradoxically, upon HIV-1 infection, myeloid cells might also promote viral pathogenesis through trans-infection, a mechanism that promotes HIV-1 transmission to target cells via viral
Giulia Caron et al.
Journal of medicinal chemistry, 48(9), 3269-3279 (2005-04-29)
Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in
Seung Jun Lee et al.
Toxicology letters, 232(2), 458-465 (2014-12-03)
In the present study, we evaluated the inhibitory potentials of finasteride for the major human hepatic UDP-glucuronosyltransferases (UGTs) (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B7, and UGT2B15) in vitro using LC-MS/MS by specific marker reactions in human liver microsomes (except for
Wenhao Wu et al.
Journal of colloid and interface science, 374(1), 226-231 (2012-02-22)
The pH-dependent behavior, including the transformation of 1-naphthol by oxidative polymerization to form precipitates in solution and the adsorption of 1-naphthol onto carbon nanotubes (CNTs), was examined. Neglecting the precipitate loss of 1-naphthol and possibly of similar chemicals may result
Xiaoying Guo et al.
Environmental science & technology, 46(13), 7252-7259 (2012-06-09)
The sorption behavior of four hydrophobic organic contaminants (HOCs) (i.e., phenanthrene, naphthalene, lindane, and 1-naphthol) by three types of polymers namely polyethylene (PE), polystyrene (PS), and polyphenyleneoxide (PPO) was examined in this work. The organic carbon content-normalized sorption coefficients (K(oc))
Yasuhiro Tajima et al.
Cytotechnology, 67(4), 585-592 (2013-07-31)
Nitensidine A is a guanidine alkaloid isolated from Pterogyne nitens, a common plant in South America. To gain insight into the biological activity of P. nitens-produced compounds, we examined herein their biological effects on osteoclasts, multinucleated giant cells that regulate
Jizheng Dang et al.
Bioorganic & medicinal chemistry letters, 23(3), 646-649 (2012-12-27)
At pH from 5.5 to 7.6, absorptivity of 4-nitro-1-naphthol at 450 nm is over 2.1-fold of that of para-nitrophenol at 405 nm and over 9.6-fold of that of ortho-nitrophenol at 415 nm. On 4-nitro-1-naphthyl-β-D-galactopyranoside at pH 7.4, catalytic efficiency of
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