Showing 1-30 of 71 results for "34037"
Abdelhamid Abbas et al.
International journal of food microbiology, 161(3), 172-181 (2013-01-22)
The ochratoxin A (OTA) polyketide synthase otapks gene has been cloned from Penicillium verrucosum. A P. verrucosum mutant in which the otapksPV gene has been interrupted cannot synthesize ochratoxin A. The protein is most similar to the citrinin polyketide synthase...
Betty C Galarreta et al.
Analytical and bioanalytical chemistry, 405(5), 1613-1621 (2012-11-29)
A selective aptameric sequence is adsorbed on a two-dimensional nanostructured metallic platform optimized for surface-enhanced Raman spectroscopy (SERS) measurements. Using nanofabrication methods, a metallic nanostructure was prepared by electron-beam lithography onto a glass coverslip surface and embedded within a microfluidic...
Xia Geng et al.
Analytical and bioanalytical chemistry, 405(8), 2443-2449 (2013-01-31)
By taking advantage of the intrinsic fluorescence of ochratoxin A (OTA), we present a fluorescence anisotropy approach for rapid analysis of the interactions between OTA and aptamers. The specific binding of OTA with a 36-mer aptamer can induce increased fluorescence...
Hongguang Lian et al.
Toxicology letters, 226(2), 214-221 (2014-02-15)
Ochratoxin A (OTA), a mycotoxin produced by ubiquitous Aspergilli, is carcinogenic, teratogenic, and nephrotoxic in both humans and animals. Our previous study found that OTA induced DNA double-strand breaks (DSBs) and resulted in G2 phase arrest in human gastric epithelium...
Periasamy Ramyaa et al.
Biochimica et biophysica acta, 1840(1), 681-692 (2013-10-29)
Ochratoxin A (OTA), a mycotoxin, causes extensive cell damage, affecting liver and kidney cells. OTA toxicity is fairly well characterized where oxidative stress is believed to play a role, however, the sequence of molecular events after OTA-exposure, have not been...
Asya Akbar et al.
International journal of food microbiology, 188, 116-121 (2014-08-12)
Two new species of Aspergillus (A. aculeatinus, A. sclerotiicarbonarius) were previously isolated from coffee in Thailand. The objective of this study was to examine the effect of interacting environmental factors of water availability (water activity, aw) and temperature on lag...
Antonia Gallo et al.
International journal of food microbiology, 179, 10-17 (2014-04-05)
Ochratoxin A (OTA) is a potent mycotoxin produced by Aspergillus and Penicillium species and is a common contaminant of a wide variety of food commodities, with Aspergillus carbonarius being the main producer of OTA contamination in grapes and wine. The...
Qinghua Wu et al.
Current drug metabolism, 12(1), 1-10 (2011-01-13)
Ochratoxin A (OTA) as a carcinogenic of group 2B to humans is produced by various fungi strains as Aspergillus and Penicillium. It is one of the most common contaminant in foodstuff. OTA is nephrotoxic, hepatotoxic, teratogenic, and immunotoxic and is...
S C Duarte et al.
Food chemistry, 138(2-3), 1055-1061 (2013-02-16)
A reliable exposure assessment of mycotoxin contamination relies on their unambiguous identification and accurate quantification. With such purpose, a new analytical methodology was developed for evaluation of ochratoxin A (OTA) contamination in pork. Briefly OTA extraction from minced muscle samples...
Jihea Moon et al.
Journal of nanoscience and nanotechnology, 13(11), 7245-7249 (2013-11-20)
Ochratoxin A (OTA), classified as a possible human renal carcinogen (group 2B), is a potent toxin as to cause the nephropathy. Many methods have been proposed and reviewed for OTA determination in food and agricultural products. However, current analytical procedures...
Stefano Fiori et al.
International journal of food microbiology, 189, 45-50 (2014-08-13)
Aspergillus spp. infection of grape may lead to ochratoxin A (OTA) contamination in processed beverages such as wine and grape juice. The aim of the current study was to evaluate the biocontrol potential of two non-fermenting (Cyberlindnera jadinii 273 and...
Jeffrey D Palumbo et al.
Journal of food protection, 76(4), 702-706 (2013-04-12)
In a previous study, inedible almond pick-out samples were assayed for aflatoxin and aflatoxigenic Aspergillus species. These samples contained high populations of black-spored Aspergillus section Nigri species. To investigate whether these species may contribute to the total potential mycotoxin content...
Lizhi Wang et al.
Food chemistry, 138(2-3), 1048-1054 (2013-02-16)
An effective method was developed for screening licorice roots and fritillary bulbs for contamination by aflatoxin B(1) and ochratoxin A using high-performance liquid chromatography connected to tandem mass spectrometry (HPLC-MS/MS). The samples were pre-concentrated and purified using solid-phase extraction, which...
Xin Li et al.
Biosensors & bioelectronics, 49, 426-432 (2013-06-29)
Mycotoxins are highly toxic contaminants and have induced health threat to human and animals. Aflatoxin B1 (AFB1), ochratoxin A (OTA) and zearalenone (ZEA) commonly occur in food and feed. A multi-component immunochromatographic assay (ICA) was developed for rapid and simultaneous...
Mohammadreza Khalesi et al.
Environmental toxicology and pharmacology, 32(2), 113-121 (2011-08-17)
Mycotoxin biosynthesis is affected by peculiar agro-ecosystem dependent conditions. Accordingly, the correlation between mycotoxin contamination and environmental condition change scenarios should be carefully considered. This is because fungal colonization and mycotoxin contamination could critically impair the availability of food products...
Jorge A Cruz-Aguado et al.
Journal of agricultural and food chemistry, 56(22), 10456-10461 (2008-11-06)
This work describes the identification of an aptamer that binds with high affinity and specificity to ochratoxin A (OTA), a mycotoxin that occurs in wheat and other foodstuffs, and a quantitative detection method for OTA based on the use of...
Taihua Li et al.
Biosensors & bioelectronics, 42, 403-408 (2012-12-12)
The phenomenon of fluorescence quenching of an antibody by a specific ligand was applied in developing a technique for detection of mycotoxins, such as aflatoxin B₁ (AFB₁), ochratoxin A, and zearalenone. Studies showed that the intrinsic fluorescence of tryptophan (Trp)...
Markus Schmidt-Heydt et al.
International journal of food microbiology, 192, 1-6 (2014-10-04)
Penicillium verrucosum is a fungus that can produce ochratoxin A and citrinin, two structurally related nephrotoxic mycotoxins. P. verrucosum usually occurs on wheat but can occasionally also be found in NaCl rich habitats such as salted cheeses or olives, indicating...
Giuseppe Cozzi et al.
Toxins, 5(1), 49-59 (2013-01-04)
Grape berries attacked by Lobesia botrana larvae are more easily infected by Aspergillus section Nigri (black aspergilli) ochratoxigenic species. Two-year field trials were carried out in Apulia (Italy) to evaluate a bioinsecticide control strategy against L. botrana and the indirect...
Sofia C Duarte et al.
Veterinary microbiology, 154(1-2), 1-13 (2011-06-07)
Mycotoxins are secondary fungal metabolites, whose presence in feed- and foodstuffs is unavoidable. Ochratoxin A (OTA) is one of the known mycotoxins with greatest public health and agro-economic significance. Several toxic effects have been ascribed following exposure, namely nephrotoxicity, as...
Valeria Sorrenti et al.
Toxins, 5(10), 1742-1766 (2013-10-25)
Ochratoxin A (OTA) is a mycotoxin involved in the development of different types of cancers in rats, mice and humans. A growing number of in vitro and in vivo studies has been collected and has described evidence compatible with a...
Juanjuan Zheng et al.
Toxicology and applied pharmacology, 268(2), 123-131 (2013-02-09)
Oxidative stress and DNA damage are the most studied mechanisms by which ochratoxin A (OTA) induces its toxic effects, which include nephrotoxicity, hepatotoxicity, immunotoxicity and genotoxicity. Zinc, which is an essential trace element, is considered a potential antioxidant. The aim...
Alicia Rodríguez et al.
International journal of food microbiology, 178, 113-119 (2014-04-02)
Iberian dry-cured ham is colonised by moulds during the ripening process. The environmental conditions occurring during the process including the salt content predisposes the surface to colonisation by Penicillium species, including Penicillium nordicum which can contaminate the curing ham with...
Irène Ahou Kouadio et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(6), 1969-1979 (2012-03-28)
The effect of coffee cherries quantity put out for sun drying on the kinetics of the drying, chemical components variation, fungal growth and ochratoxin A production was evaluated. The results showed that the more coffee cherries quantity on the drying...
S Sezin Palabiyik et al.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 65(6), 853-861 (2013-01-22)
This study was designed to investigate the possible protective effect of lycopene against the renal toxic effects of OTA. Male Sprague-Dawley rats (<200 g, n=6) were treated with OTA (0.5 mg/kg/day) and/or lycopene (5 mg/kg/day) by gavage for 14 days....
Daisuke Hibi et al.
Toxicology, 304, 92-99 (2012-12-25)
Ochratoxin A (OTA) is a mycotoxin produced by fungal species and is carcinogenic targeting the S3 segment of the renal proximal tubules in rodents. We previously reported that exposure of gpt delta rats to OTA induced both mutations in the...
Vladimir Ostry et al.
Toxins, 5(9), 1574-1586 (2013-09-21)
Ochratoxin A (OTA) is a very important mycotoxin, and its research is focused right now on the new findings of OTA, like being a complete carcinogen, information about OTA producers and new exposure sources of OTA. Citrinin (CIT) is another...
Wei Ma et al.
Biosensors & bioelectronics, 42, 545-549 (2012-12-25)
A simple and ultrasensitive method was developed for the detection of Ochratoxin A, utilizing an aptamer as a molecular recognition probe and real-time quantitative PCR (RT-qPCR) amplification of its complementary DNA as signal generators. Under the optimized conditions, the cycle...
Tânia Leal et al.
Food chemistry, 300, 125204-125204 (2019-07-25)
Analytical chromatographic techniques for mycotoxins control are well established, but they often depend on costly immunoaffinity sample clean-up. Serum albumins, particularly that from bovine origin (BSA), have stable binding affinity towards some mycotoxins, and can be cheaper alternative receptors for...
Alicia Rodríguez et al.
International journal of food microbiology, 194, 71-77 (2014-12-02)
Dry-cured sausages are colonised by moulds during the ripening process. The temperature and the salt content (which affects water activity, aw) predispose the surface to colonisation by Penicillium species, including Penicillium nordicum and Penicillium verrucosum which can lead to contamination...

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