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T Ulens et al.
Journal of animal science, 93(2), 627-636 (2014-12-31)
This study evaluated the effect of feed form and grinding intensity of the pig diet and the interaction between both on the particulate matter (PM) concentrations inside a pig nursery and the growth performances of weanling pigs. Four diets were
Y Liu et al.
Journal of dental research, 92(8), 746-752 (2013-06-01)
While proanthocyanidins (PA) are effective in improving collagen's resistance to collagenolytic degradation, the direct incorporation of PA into an adhesive system is detrimental to the light-curing thereof. Conversely, the use of PA as a primer could circumvent this issue, but
Shailendra Asthana et al.
Journal of agricultural and food chemistry, 63(32), 7236-7244 (2015-08-12)
The structure-activity relationships of four hydroxycoumarins, two with the hydroxyl group on the aromatic ring of the molecule and two with the hydroxyl group replacing hydrogen of the pyrone ring, and their interactions with mushroom tyrosinase were studied. These compounds
Meng-Mei Ma et al.
Food chemistry, 194, 237-246 (2015-10-17)
This study evaluated the effects of alkali extraction, enzymatic hydrolysis, shear emulsifying assisted enzymatic hydrolysis, and particle size distribution on the chemical composition and the structural, physicochemical, and functional properties of deoiled cumin dietary fibers (AEDF, EHDF and SEDF). Compared
Hui Xuan Lim et al.
Journal of immunology (Baltimore, Md. : 1950), 193(11), 5453-5460 (2014-11-02)
Myeloid-derived suppressor cells (MDSCs) are major immunosuppressive cells that lead to T cell defects in cancer. IL-18 is important in inflammatory and immune responses. IL-18 has been reported to have a dual effect on tumor progression, as it not only
G P Lv et al.
Journal of pharmaceutical and biomedical analysis, 109, 105-111 (2015-03-15)
It was shown that different extracts had significant differences in the toxicity of Polygonum multiflorum. In this study, the effect of sample preparation on components and liver toxicity of different extracts from P. multiflorum were determined. Hepatoxic components were discovered
Rushd Khalaf et al.
Journal of chromatography. A, 1397, 11-18 (2015-05-03)
The purification of therapeutic peptides is most often performed using one or more reversed phase chromatography steps. This ensures high purities while keeping the costs of purification under control. In this paper, a doped reversed phase chromatographic material is tested
Ghada M Hadad et al.
Journal of chromatographic science, 52(7), 617-623 (2013-07-03)
A high-performance liquid chromatography method employing diode array detection was developed to determine levels of the major catechins, proanthocyanidin (procyanidin B2), caffeine, thymoquinone and carvacrol and its isomer, thymol, which are present in different natural complex matrices found in commercial
Ali Rezaei-Golmisheh et al.
Iranian journal of basic medical sciences, 18(7), 691-699 (2015-09-12)
The current study was aimed to determine the bioactive constituents and biological effects of the Crataegus monogyna ethanolic extracts from bark, leaves and berries on hypercholesterolemia. Oleanolic acid, ursolic acid, quercetin and lupeol concentrations were quantified by HPLC. Total phenol
Marwa A A Ragab et al.
Luminescence : the journal of biological and chemical luminescence, 30(6), 760-767 (2014-11-26)
A new combination of ibuprofen (NSAID) and famotidine (H2 receptor antagonist) was recently approved by the FDA. It was formulated to relief pain while decreasing the risk of ulceration, which is a common problem for patients receiving NSAID. A rapid
Ariene A Leme et al.
Journal of biomechanics, 48(10), 2067-2071 (2015-04-15)
Degradation of the adhesive interface contributes to the failure of resin composite restorations. The hydrophilicity of the dentin matrix during and after bonding procedures may result in an adhesive interface that is more prone to degradation over time. This study
Theresa A Isbell et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 980, 65-71 (2015-01-16)
The determination of morphine and its isobaric metabolites morphine-3-beta-d-glucuronide (M3G) and morphine-6-beta-d-glucuronide (M6G) is useful for therapeutic drug monitoring and forensic identification of drug use. In particular, capillary electrophoresis with mass spectrometry (CE-MS) represents an attractive tool for opioid analysis.
Lisa A Levin et al.
PloS one, 10(7), e0131080-e0131080 (2015-07-15)
Carbonate communities: The activity of anaerobic methane oxidizing microbes facilitates precipitation of vast quantities of authigenic carbonate at methane seeps. Here we demonstrate the significant role of carbonate rocks in promoting diversity by providing unique habitat and food resources for
Liyun Ma et al.
Journal of chromatography. A, 1376, 64-73 (2014-12-22)
Cucurbit[7]uril (CB7), one host macromolecule, possesses a hydrophobic inner cavity and two identical hydrophilic carbonyl fringe portals, thus interacting with a variety of guest molecules through hydrophobic, hydrogen bonding and ion-dipole interactions. These characteristics make CB7 a good candidate as
Shuliang Liu et al.
Journal of immunology (Baltimore, Md. : 1950), 183(9), 5537-5547 (2009-10-09)
Citrobacter koseri is a Gram-negative bacterium that can cause a highly aggressive form of neonatal meningitis, which often progresses to establish multifocal brain abscesses. Despite its tropism for the brain parenchyma, microglial responses to C. koseri have not yet been
María González-Núñez et al.
Disease models & mechanisms, 8(11), 1427-1439 (2015-09-24)
The activin receptor-like kinase 1 (ALK-1) is a type I cell-surface receptor for the transforming growth factor-β (TGF-β) family of proteins. Hypertension is related to TGF-β1, because increased TGF-β1 expression is correlated with an elevation in arterial pressure (AP) and
Lu Liu et al.
Journal of pharmaceutical sciences, 103(7), 1979-1986 (2014-05-17)
We studied the effects of pH and solution additives on freezing-induced perturbations in the tertiary structure of a monoclonal antibody (mAb) by intrinsic tryptophan fluorescence spectroscopy. In general, freezing caused perturbations in the tertiary structure of the mAb, which were
Lukáš Krásný et al.
Journal of mass spectrometry : JMS, 50(6), 802-811 (2015-07-15)
We report an MS-based workflow for identification of phosphorylated peptides from trypsinized protein mixtures and cell lysates that is suitable for high-throughput sample analysis. The workflow is based on an in situ enrichment on matrix-assisted laser desorption/ionization (MALDI) plates that
S Y Shu et al.
Genetics and molecular research : GMR, 14(2), 3400-3408 (2015-05-13)
Non-syndromic cleft of the lip and/or palate (NSCLP) is a very common birth defect; the poliovirus receptor-like 1 gene (PVRL1) has been identified as a genetic risk factor for NSCLP in patients from Norway, the Philippines, and South America. Given
Alessio Ciulli et al.
Journal of medicinal chemistry, 49(16), 4992-5000 (2006-08-04)
Mapping interactions at protein-ligand binding sites is an important aspect of understanding many biological reactions and a key part of drug design. In this paper, we have used a fragment-based approach to probe "hot spots" at the cofactor-binding site of
Noel L Davison et al.
Biomaterials, 35(26), 7441-7451 (2014-06-15)
A resorbable bone graft substitute should mimic native bone in its capacity to support bone formation and be remodeled by osteoclasts (OCl) or other multinucleated cells such as foreign body giant cells (FBGC). We hypothesize that by changing the scale
F Munarin et al.
International journal of biological macromolecules, 72, 199-209 (2014-08-12)
Pectin-based biocomposite hydrogels were produced by internal gelation, using different hydroxyapatite (HA) powders from commercial source or synthesized by the wet chemical method. HA possesses the double functionality of cross-linking agent and inorganic reinforcement. The mineralogical composition, grain size, specific
Changyong Yim et al.
Scientific reports, 5, 10674-10674 (2015-06-04)
Nanoporous anodic aluminum oxide (AAO) microcantilevers are fabricated and MIL-53 (Al) metal-organic framework (MOF) layers are directly synthesized on each cantilever surface by using the aluminum oxide as the metal ion source. Exposure of the MIL53-AAO cantilevers to various concentrations
J Brent Friesen et al.
Journal of chromatography. A, 1377, 55-63 (2014-12-30)
Rational solvent system selection for countercurrent chromatography and centrifugal partition chromatography technology (collectively known as countercurrent separation) studies continues to be a scientific challenge as the fundamental questions of comparing polarity range and selectivity within a solvent system family and
Marija Stojanović et al.
Biotechnology and applied biochemistry, 62(4), 458-466 (2014-09-17)
Fatty acid (FA) ascorbyl esters are recently emerging food, cosmetic, and pharmaceutical additives, which can be prepared in an eco-friendly way by using lipases as catalysts. Because they are amphiphilic molecules, which possess high free radical scavenging capacity, they can
Nam Ah Kim et al.
Drug development and industrial pharmacy, 41(2), 300-306 (2014-02-08)
Correlation of thermodynamic and secondary structural stability of proteins at various buffer pHs was investigated using differential scanning calorimetry (DSC), dynamic light scattering (DLS) and attenuated total reflection Fourier-transform infrared spectroscopy (ATR FT-IR). Recombinant human epithelial growth factor (rhEGF) was
Yuting Chen et al.
Nanoscale, 7(17), 7770-7779 (2015-04-08)
Herein, we present a systematic study on the development, optical optimization and sensing applicability of colored photonic coatings based on nanoporous anodic alumina films grown on aluminum substrates. These optical nanostructures, so-called distributed Bragg reflectors (NAA-DBRs), are fabricated by galvanostatic
Ondrej Cerny et al.
Journal of immunology (Baltimore, Md. : 1950), 194(10), 4901-4913 (2015-04-17)
The adenylate cyclase toxin-hemolysin (CyaA) plays a key role in the virulence of Bordetella pertussis. CyaA penetrates complement receptor 3-expressing phagocytes and catalyzes uncontrolled conversion of cytosolic ATP to the key second messenger molecule cAMP. This paralyzes the capacity of
Meera Gujjar et al.
International journal of pharmaceutics, 472(1-2), 362-368 (2014-07-01)
The purpose of this study was to compare the transdermal permeation of a model compound, diclofenac diethylamine, from a hydrophilic and lipophilic vehicle across in vitro models simulating compromised skin. Mineral oil served as a lipophilic vehicle while 10mM phosphate
Juan Liu et al.
Bio-medical materials and engineering, 26 Suppl 1, S2123-S2132 (2015-09-26)
The Yinzhihuang injection, a traditional Chinese medicine, has been the recent target of increasing interest due to its anti-inflammatory properties. The molecular basis by which Yinzhihuang injection could cure Riemerella anatipestifer (RA) serositis in ducks is unclear. This study evaluated
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