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Mak A Saito et al.
Science (New York, N.Y.), 345(6201), 1173-1177 (2014-09-06)
Marine primary productivity is strongly influenced by the scarcity of required nutrients, yet our understanding of these nutrient limitations is informed by experimental observations with sparse geographical coverage and methodological limitations. We developed a quantitative proteomic method to directly assess
Zille Rubab et al.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 26(1), 19-25 (2015-01-13)
Patients on hemodialysis (HD) are usually anemic because of defective erythropoeisis. Hepcidin is a polypeptide that regulates iron homeostasis and could serve as an indicator of functional iron deficiency in patients with end-stage renal disease (ESRD); this may also aid
N M Makarova et al.
Klinicheskaia laboratornaia diagnostika, (1)(1), 42-44 (2013-07-03)
The sample for examination included 52 patients with chronic cardiac failure and 26 patients with anemia amongst. The expected increase of production of prohepsidin against the background of increased serum concentrations of anti-inflammatory cytokines was not detected. The tendency to
Robert C Hider et al.
Metal ions in life sciences, 13, 229-294 (2014-01-29)
Iron is a redox active metal which is abundant in the Earth's crust. It has played a key role in the evolution of living systems and as such is an essential element in a wide range of biological phenomena, being
Stanley Zlotkin et al.
JAMA, 310(9), 938-947 (2013-09-05)
In sub-Saharan Africa, malaria is a leading cause of childhood morbidity and iron deficiency is among the most prevalent nutritional deficiencies. In 2006, the World Health Organization and the United Nations Children's Fund released a joint statement that recommended limiting
Thomas A Russo et al.
Infection and immunity, 82(6), 2356-2367 (2014-03-26)
Hypervirulent (hypermucoviscous) Klebsiella pneumoniae (hvKP) strains are an emerging variant of "classical" K. pneumoniae (cKP) that cause organ and life-threatening infection in healthy individuals. An understanding of hvKP-specific virulence mechanisms that enabled evolution from cKP is limited. Observations by our
Darius J R Lane et al.
Biochimica et biophysica acta, 1845(2), 166-181 (2014-01-30)
Cancer is a major public health issue and, despite recent advances, effective clinical management remains elusive due to intra-tumoural heterogeneity and therapeutic resistance. Iron is a trace element integral to a multitude of metabolic processes, including DNA synthesis and energy
Erik T Yukl et al.
Biochemistry, 52(52), 9447-9455 (2013-12-11)
The di-heme enzyme MauG catalyzes the oxidative biosynthesis of a tryptophan tryptophylquinone cofactor on a precursor of the enzyme methylamine dehydrogenase (preMADH). Reaction of H2O2 with the diferric form of MauG, or reaction of O2 with diferrous MauG, forms the
S J Geetha et al.
TheScientificWorldJournal, 2013, 315890-315890 (2013-12-10)
Under field conditions, inoculated rhizobial strains are at a survival disadvantage as compared to indigenous strains. In order to out-compete native rhizobia it is not only important to develop strong nodulation efficiency but also increase their competence in the soil
Sohail Amjad et al.
Pakistan journal of pharmaceutical sciences, 27(3), 445-452 (2014-05-09)
In Pakistan, a funded flour fortification program was launched for malnourished population, residing mainly in rural low income areas, but the urban population having comparatively better nutritional as well as economic status was focused wherein excessive intake of fortificants might
Tea Romih et al.
The Science of the total environment, 508, 76-84 (2014-12-02)
The aim of this study was to determine whether citric acid adsorbed onto cobalt ferrite (CoFe2O4) nanoparticles (NPs) influences the bioavailability of their constituents Co and Fe. Dissolution of Co and Fe was assessed by two measures: (i) in aqueous
I P Zaĭtseva et al.
Voenno-meditsinskii zhurnal, 334(3), 36-40 (2013-07-03)
According to examination, with the help of emission spectrum analysis method, of 24 cadets-athletes of different specialization it was determined that during physical exercise in summer and in winter loss of ferrum and copper with excrements exceeded the intake if
Surendra K Pradhan et al.
Journal of water and health, 11(4), 581-589 (2013-12-18)
Wastewater is an important source of pathogenic enteric microorganisms in surface water and a major contaminating agent of drinking water. Although primary and secondary wastewater treatments reduce the numbers of microorganisms in wastewater, significant numbers of microbes can still be
Nosratola D Vaziri
Nephrology news & issues, 28(2), 4-5 (2014-03-22)
Loss of blood associated with hemodialysis procedures and laboratory testing, together with impaired iron absorption due to elevation of hepcidin, invariably cause iron deficiency in end-stage renal disease patients. For this reason, nearly all ESRD patients require intravenous iron to
Yuhoon Hwang et al.
Journal of environmental sciences (China), 25(11), 2177-2184 (2014-02-21)
Nanoscale zero-valent iron (NZVI) is considered to have potential to reduce nitrate in the concentrate generated by high pressure membrane processes aimed at water reuse. However, it is necessary to verify the effect of the matrix components in the concentrates
Carmen S D Rodrigues et al.
Environmental technology, 35(9-12), 1307-1319 (2014-04-08)
This study aims to investigate the efficiency of individual and integrated processes applied to organic matter abatement and biodegradability improvement of a polyester dyeing wastewater, namely coagulation/flocculation combined with Fenton's reagent (Approach 1), Fenton oxidation alone (Approach 2) and its
Caterina Borgna-Pignatti et al.
British journal of haematology, 167(1), 121-126 (2014-07-06)
The risk of developing hepatocellular carcinoma (HCC) in patients with thalassaemia is increased by transfusion-transmitted infections and haemosiderosis. All Italian Thalassaemia Centres use an ad hoc form to report all diagnoses of HCC to the Italian Registry. Since our last
Joseph E Kiss et al.
JAMA, 313(6), 575-583 (2015-02-11)
Although blood donation is allowed every 8 weeks in the United States, recovery of hemoglobin to the currently accepted standard (12.5 g/dL) is frequently delayed, and some donors become anemic. To determine the effect of oral iron supplementation on hemoglobin
Tim M Conway et al.
Nature, 511(7508), 212-215 (2014-07-11)
Dissolved iron is an essential micronutrient for marine phytoplankton, and its availability controls patterns of primary productivity and carbon cycling throughout the oceans. The relative importance of different sources of iron to the oceans is not well known, however, and
Isabelle R Miousse et al.
Radiation research, 182(1), 92-101 (2014-06-25)
There is an increasing need to better understand the long-term health effects of high-linear energy transfer (LET) radiation due to exposure during space missions, as well as its increasing use in clinical treatments. Previous studies have indicated that exposure to
ESAs and irons in the pipeline: how do they differ?
Anatole Beserab
Nephrology news & issues, 27(7), Supp 6-Supp 9 (2013-07-17)
Nicole Rietzschel et al.
Molecular and cellular biology, 35(2), 370-378 (2014-11-05)
Iron is an essential, yet at elevated concentrations toxic trace element. To date, the mechanisms of iron sensing by eukaryotic iron-responsive transcription factors are poorly understood. The Saccharomyces cerevisiae transcription factor Yap5, a member of the Yap family of bZIP
Abigail Trejo-Hernández et al.
The ISME journal, 8(10), 1974-1988 (2014-04-18)
Inter-kingdom and interspecies interactions are ubiquitous in nature and are important for the survival of species and ecological balance. The investigation of microbe-microbe interactions is essential for understanding the in vivo activities of commensal and pathogenic microorganisms. Candida albicans, a
Annalisa Pastore et al.
Journal of neurochemistry, 126 Suppl 1, 43-52 (2013-07-24)
Reduced levels of the protein frataxin cause the neurodegenerative disease Friedreich's ataxia. Pathology is associated with disruption of iron-sulfur cluster biosynthesis, mitochondrial iron overload, and oxidative stress. Frataxin is a highly conserved iron-binding protein present in most organisms. Despite the
Sandro Silva-Gomes et al.
Frontiers in cellular and infection microbiology, 3, 96-96 (2013-12-25)
Due to their chemical versatility, transition metals were incorporated as cofactors for several basic metabolic pathways in living organisms. This same characteristic makes them potentially harmful, since they can be engaged in deleterious reactions like Fenton chemistry. As such, organisms
Hong-Seok Kim et al.
Chemosphere, 113, 93-100 (2014-07-30)
Effects of anions (NO3(-), HCO3(-), Cl(-), SO4(2-)) and humic acid on the reactivity and core/shell chemistries of polyacrylic acid-coated nanoscale zero-valent iron (PAA-NZVI) and inorganically modified NZVI (INORG-NZVI) particles were investigated. The reactivity tests under various ion concentrations (0.2-30mN) revealed
Microcytic anemia.
Thomas G DeLoughery
The New England journal of medicine, 371(26), 2537-2537 (2014-12-30)
L Iu Milovanova et al.
Terapevticheskii arkhiv, 85(6), 17-24 (2013-07-23)
To study the clinical significance of determining the serum concentration of phosphorus and calcium metabolism regulators--the morphogenetic proteins FGF-23 and Klotho in patients with different stages of chronic kidney disease (CKD). The serum levels of FGF-23 (a human FGF-23 ELISA
Matthew Stroh et al.
Biochemical pharmacology, 88(4), 573-583 (2013-12-24)
A popular, if not centric, approach to the study of an event is to first consider that of the simplest cause. When dissecting the underlying mechanisms governing idiopathic diseases, this generally takes the form of an ab initio genetic approach.
Jungho Ryu et al.
Journal of nanoscience and nanotechnology, 13(5), 3422-3426 (2013-07-19)
Spinel structured highly dense NiMn2O4-based (NMO) negative temperature coefficient (NTC) thermistor thick films were fabricated by aerosol-deposition at room temperature. To enhance the thermistor B constant, which represents the temperature sensitivity of the NMO thermistor material, Co and Co-Fe doping
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