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Stable Isotopes
ISOTEC® Stable Isotopes are stable isotope compounds, ranging from gases to complex molecules, that are useful for tracer studies in proteomics and metabolomics, agents for MRI / MRS, and in a wide range of other biomedical applications.
Amino Acids Reference Chart
Amino acid reference chart contains the twenty amino acids found in eukaryotes, grouped according to their side chains and charge. Discover our full product line of amino acids, including Alanine, Isoleucine, Leucine, Valine, Phenylalanine, Tryptophan, Tyrosine, Aspargine, Cysteine, Glutamine...
Generating organotypic 3D skin cultures as an in-vitro model of the human epidermis
3D cell culture protocol for generating epidermal human skin tissue using primary human keratinocytes, dermal fibroblasts, and collagen-coated transwell inserts.
Serotonin Synthesis and Metabolism
Serotonin (5-hydroxytryptamine) is principally found stored in three main cell types - i) serotonergic neurons in the CNS and in the intestinal myenteric plexus, ii) enterochromaffin cells in the mucosa of the gastrointestinal tract, and iii) in blood platelets. Metabolism...
Melatonin Receptors
We offer many products related to melatonin receptors for your research needs.
β-Adrenoceptors
β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.
Tissue Dissociation Enzymes: Collagenase, Dispase, and Liberase
Enzyme Explorer Key Resource: Collagenase Guide.Collagenases, enzymes that break down the native collagen that holds animal tissues together, are made by a variety of microorganisms and by many different animal cells.
Somatostatin Receptors
Sigma-Aldrich offers many products related to somatostatin receptors for your research needs.
Analysis of Pesticide Residues in Cannabis Using QuEChERS Extraction and Cleanup Followed by GC/MS/MS Analysis
Compared to conventional PSA/C18/GCB cleanup, cannabis extracts cleaned with the Supel QuE Verde mixture showed lower GC/MS background, and better recoveries for many pesticides.
Dipeptidyl Peptidase IV
Native DPPIV is a ubiquitous type II transmembrane glycoprotein and a serine protease of the S9 prolyl-oligopeptidase family. In vivo, it is synthesized with a signal peptide which functions as the membrane anchoring domain.
Cyclin-dependent Kinases (CDKs)
Cyclin dependent kinases (CDKs) are typical serine/threonine kinases that display the 11 subdomains shared by all kinases. The complete sequence of the Homo sapiens genome shows that among the ~30,000 predicted genes, there are 13 CDKs and 25 cyclins. Eleven...
Sensing Scents: Olfactory (Smell) Perception
A discussion of the process of smell perception and its ties to memory and emotion
Nuclear Receptors (Non-Steroids)
We offer many products related to non-steroid nuclear receptors for your research needs.
Authenticated Lung Cancer Cell Lines for Cancer Research
Select lung cancer cell lines authenticated by ECACC based on associated mutations and diagnosis classifications. Browse squamous cell, adenocarcinoma, SCLC, and NSCLC cell lines for drug response, toxicology, in vitro models including A549, NCI H292 and more.
SPME-GC-MS Determination of Phthalate Esters in Ramen Noodle Flavor Packets
A sensitive, quantitative, and reproducible SPME-GC/MS procedure was developed by Supelco for the extraction of phthalate esters from oily food matrices, such as the flavored oils included with ramen noodle kits.
Analysis of Pesticides in Baby Food by Solid Phase Microextraction (SPME) Using a New Overcoated Fiber
A direct immersion SPME method using a new overcoated SPME fiber was developed for the extraction of pesticides from pureed prune baby food.
Canonical Wnt / β-Catenin Signaling
We review the Wnt signaling pathway (also, canonical Wnt or beta (β)-catenin pathway) and provide links to related products at sigmaaldrich.com.
VEGF Pathway
Read review on VEGF signaling pathway (Vascular endothelial growth factor (VEGF)/VEGF receptor) and find related products.
Cancer Research Techniques
By focusing on analysis techniques and protocols specific for Cancer Research, we are putting your research needs first. Protein Tyrosine Kinase and Phosphatase Expression Profiling in Cancer Research.
Tissue Dissociation Guide: Collagenase, Dispase, and Liberase Enzyme Types
Collagenase Guide.Collagenases, enzymes that break down the native collagen that holds animal tissues together, are made by a variety of microorganisms and by many different animal cells.
PTK/PTP Expression Profiling
PTK/PTP Expression Profiling
Organic Field Effect Transistors Based on DNTT and Related Organic Semiconductors
Highly extended polyacenes such as pentacene and naphthacene have been essential organic semiconductors for high-performance organic field-effect transistors (OFETs). Among the range of thienoacene-based organic semiconductors, materials with an internal thieno[3,2-b]thiophene substructure, such as DNTT and BTBT, have shown...
Nanostructured Olivine-based Cathode Materials for Lithium-ion Batteries
Due to the adverse impact of the continued use of fossil fuels on the earth’s environment and climate, researchers have been asked to develop new approaches for producing power using renewable sources like wind and solar energy
DNA Damage and Repair
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
Polymer-Sorted Semiconducting Carbon Nanotubes for Transistors and Solar Cells
Single-walled carbon nanotubes (SWCNTs) are promising materials for use in the active channel of field-effect transistors (FETs), photoabsorbing layers of solar cells and photodetectors because of their ultrafast charge transport mobility.
MISSION™ CRISPRa Synergistic Activation Mediator (SAM)
MISSION™ CRISPRa Synergistic Activation Mediator (SAM)
TRC Library Citations
TRC 1.5 human and mouse shRNA libraries
Immunohistochemistry: Current Applications in Skin Cancer
Immunohistochemistry (IHC) techniques and applications have greatly improved, dermatopathology is still largely based on H&E stained slides.This paper outlines ways in which IHC antibodies can be utilized for dermatopathology.