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372382
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Showing 1-12 of 12 results for "372382" within Papers
Quantified pH imaging with hyperpolarized 13 C-bicarbonate
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 73(6), 2274-2282 (2015)
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 20(3), 540-550 (2020-12-15)
Approximately 10% of people with cystic fibrosis (CF) have mutations that result in little to no CFTR production and thus cannot benefit from CFTR modulators. We previously found that Amphotericin B (AmB), a small molecule that forms anion channels, restored
NMR in biomedicine, 24(8), 1006-1015 (2011-08-04)
pH is a fundamental physiological parameter that is tightly controlled by endogenous buffers. The acid-base balance is altered in many disease states, such as inflammation, ischemia and cancer. Despite the importance of pH, there are currently no routine methods for
Scientific reports, 11(1), 18134-18134 (2021-09-15)
Globally, species are migrating in an attempt to track optimal isotherms as climate change increasingly warms existing habitats. Stony corals are severely threatened by anthropogenic warming, which has resulted in repeated mass bleaching and mortality events. Since corals are sessile
Current concepts on hyperpolarized molecules in MRI.
Current Opinion in Chemical Biology, 14(1), 90-96 (2010)
Chemical communications (Cambridge, England), 52(14), 3030-3033 (2016-01-23)
A hyperpolarization technique using carbonate precursors of biocompatible molecules was found to yield high concentrations of hyperpolarized (13)C bicarbonate in solution. This approach enabled large signal gains for low-toxicity hyperpolarized (13)C pH imaging in a phantom and in vivo in
Nature, 567(7748), 405-408 (2019-03-15)
Loss-of-function mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) compromise epithelial HCO3- and Cl- secretion, reduce airway surface liquid pH, and impair respiratory host defences in people with cystic fibrosis1-3. Here we report that apical addition of amphotericin B
The influence of hydrolysis and derivatization on the determination of amino acid content and isotopic ratios in dual-labeled (13C, 15N) white clover.
Rapid Communications in Mass Spectrometry, 33(1), 21-30 (2019)
RuIII (edta) catalyzed hydrogenation of bicarbonate to formate.
Journal of Coordination Chemistry, 69(4), 650-655 (2016)
The ISME journal, 13(8), 1960-1974 (2019-03-27)
Ammonium is a central nutrient in aquatic systems. Yet, cell-specific ammonium assimilation among diverse functional plankton is poorly documented in field communities. Combining stable-isotope incubations (15N-ammonium, 15N2 and 13C-bicarbonate) with secondary-ion mass spectrometry, we quantified bulk ammonium dynamics, N2-fixation and
Oncotarget, 10(58), 6096-6110 (2019-11-07)
There is an unmet clinical need for new and robust imaging biomarkers to distinguish indolent from aggressive prostate cancer. Hallmarks of aggressive tumors such as a decrease in extracellular pH (pHe) can potentially be used to identify aggressive phenotypes. In
Magnetic resonance imaging of pH in vivo using hyperpolarized 13 C-labelled bicarbonate.
Nature, 453(7197), 940-940 (2008)
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