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Reham Mokhtar Aman et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 124, 304-318 (2018-09-09)
Apocynin (APO), a specific NADPH oxidase inhibitor, is a bioactive phytochemical that exhibits versatile pharmacological activities. However, its rapid elimination and poor bioavailability represent great challenges to pharmaceutical scientists. Accordingly, novel chitosan-based APO-loaded solid lipid nanoparticles (CS,APO - loaded SLNS)...
Guoxiang Sun et al.
Se pu = Chinese journal of chromatography, 27(4), 494-498 (2009-11-27)
To establish capillary electrophoresis fingerprint (CEFP) of Compound Danshen Dropping Pill (CDDP) by capillary zone electrophoresis, the electrophoretic separation was performed by using a 75 cm x 75 microm (the effective length of 63 cm) uncoated fused silica capillary with...
Ryohei Kono et al.
Acta histochemica et cytochemica, 47(3), 103-112 (2014-10-17)
Granulosa cells form ovarian follicles and play important roles in the growth and maturation of oocytes. The protection of granulosa cells from cellular injury caused by oxidative stress is an effective therapy for female infertility. We here investigated an effective...
Ting Xie et al.
PeerJ, 7, e7690-e7690 (2019-10-03)
Lecanicillium lecanii is an entomopathogenic fungi, which was isolated from insects suffering from disease. Now, it is an effective bio-control resource that can control agricultural pests such as whitefly and aphids. There are many studies on the control of various...
A M Hassan et al.
Applied biochemistry and biotechnology, 167(3), 581-594 (2012-05-12)
Schiff base ligand (H(3)L) was prepared from the condensation reaction of protochatechualdehyde (3,4-dihydroxybenzaldhyde)with 2-amino phenol. From the direct reaction of the ligand (H(3)L) with Co(II), Ni(II) and Cu(II) chlorides, and Fe(III)and Zn(II)nitrates in 2 M/1 L molar ratio, the five...
Chang Yoon Moon et al.
Biochemical and biophysical research communications, 423(1), 116-121 (2012-05-30)
The migration and proliferation of vascular smooth muscle cells (VSMCs) and formation of intravascular thrombosis play crucial roles in the development of atherosclerotic lesions. This study examined the effects of protocatechuic aldehyde (PCA), a compound isolated from the aqueous extract...
Bo-bo Chang et al.
Acta pharmacologica Sinica, 31(5), 638-646 (2010-04-07)
To investigate the pharmacokinetic interactions induced by content variation of the main water-soluble components of Danshen injection in rats. Intravenous Danshen injection (control) or Danshen injection with danshensu (DSS), protocatechuic aldehyde (PAL), salvianolic acid A (Sal A) or salvianolic acid...
Ahlam Jameel Abdulghani et al.
Bioinorganic chemistry and applications, 2013, 219356-219356 (2014-01-24)
A series of new di-, tri-, and tetranuclear Co(II) and Cu(II) complexes of three new diSchiff base ligands were synthesized by two different methods. The first method involved the synthesis of the three ligands from condensation reaction of 3,4-dihydroxybenzaldehyde (L'H2)...
Jin Boo Jeong et al.
Biochemical and biophysical research communications, 430(1), 381-386 (2012-11-20)
Protocatechualdehyde (PCA) is a naturally occurring polyphenol found in barley, green cavendish bananas, and grapevine leaves. Although a few studies reported growth-inhibitory activity of PCA in breast and leukemia cancer cells, the underlying mechanisms are still poorly understood. Thus, we...
Yi Sha et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(3), 371-375 (2013-05-15)
1H-NMR technology was carried out to investigate the chemical difference between 30 batches of Cibotium baronetz decoction pieces and look for new method for quality control of C. baronetz decoction pieces. Six hundreds MHz H-NMR spectroscopy and principle component analysis...
Yuehua Guo et al.
Journal of molecular modeling, 16(7), 1187-1194 (2009-12-19)
The aim of this study is to investigate the interaction between dicalcium phosphate dihydrate (CaHPO(4) x 2H(2)O, DCPD) and Protocatechuic aldehyde (C(7)H(6)O(3), Pca), which is the water-soluble constituents of Chinese Medicine, Salvia Miltiorrhiza Bunge (SMB), by calculating the absorption energy...
Tatjana D Savić et al.
Physical chemistry chemical physics : PCCP, 16(38), 20796-20805 (2014-08-29)
The surface modification of nanocrystalline TiO2 particles (45 Å) with catecholate-type ligands having different electron donating/electron withdrawing substituent groups, specifically 3-methylcatechol, 4-methylcatechol, 3-methoxycatechol, 3,4-dihydroxybenzaldehyde and 4-nitrocatechol, was found to alter the optical properties of nanoparticles in a similar way to...
Narsimha Mamidi et al.
The journal of physical chemistry. B, 116(35), 10684-10692 (2012-08-07)
Diacylglycerol (DAG) regulates a broad range of cellular functions including tumor promotion, apoptosis, differentiation, and growth. Thus, the DAG-responsive C1 domain of protein kinase C (PKC) isoenzymes is considered to be an attractive drug target for the treatment of cancer...
Aditya M Kunjapur et al.
Journal of the American Chemical Society, 136(33), 11644-11654 (2014-07-31)
Aromatic aldehydes are useful in numerous applications, especially as flavors, fragrances, and pharmaceutical precursors. However, microbial synthesis of aldehydes is hindered by rapid, endogenous, and redundant conversion of aldehydes to their corresponding alcohols. We report the construction of an Escherichia...
Nicole L Ritzert et al.
Faraday discussions, 172, 27-45 (2014-11-27)
Over the past decade, there has been a great deal of interest in graphene with regards to its electrochemical behavior. Previous studies have focused on understanding fundamental processes such as charge transfer and molecular transport at the graphene-electrolyte interface as...
3, 4-dihydroxybenzaldehyde, a fungistatic substance from green Cavendish bananas.
Mulvena D, et al.
Phytochemistry, 8(2), 393-395 (1969)
Di Zhao et al.
European journal of mass spectrometry (Chichester, England), 17(4), 395-403 (2011-10-19)
Salvianolic acid A, salvianolic acid B, danshensu, protocatechuic aldehyde, rosmarinic acid and lithospermic acid are the six major active constituents in Danshen injection. In this study, a rapid, sensitive and specific liquid chromatographic-electrospray ionization-mass spectrometry method for the simultaneous quantitative...
Hai-Yan Qin et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(8), 1199-1201 (2009-12-08)
To determine the content of total salvianolic acid in different vegetative organs of Salvia miltiorrhiza and discover the dynamic change rules of tanshinol, protocatechuic aldehyde, caffeic acid and total salvianolic acid during the whole process of grwth. HPLC-ECD was used....
Jie-Hong Ge et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 33(9), 1403-1405 (2011-01-20)
To investigate the chemical constituents of Antipathes dichotoma. The compounds were isolated and purified by column chromatography on silica gel and their structures were identified by spectral analyses and comparison with literatures. Nine compounds were obtained from A. dichotam and...
Shiqing Sun et al.
Planta medica, 77(17), 1898-1904 (2011-07-06)
Polyphenol-aspirin interactions were recently identified; however, the interaction mode and underlying mechanisms remained elusive. Here, we quantitatively assessed the potential interactions among two important polyphenolic compounds, caffeic acid (CA) and protocatechualdehyde (Pro), and aspirin in the AA-induced platelet aggregation model...
Liang Zhang et al.
Toxicology and applied pharmacology, 283(1), 50-56 (2015-01-15)
An abnormal high mobility group box 1 (HMGB1) activation and a decrease in receptor for advanced glycation end-product (RAGE) play a key role in the pathogenesis of pulmonary fibrosis. Protocatechuic aldehyde (PA) is a naturally occurring compound, which is extracted...
Jian-Ming Lü et al.
Biochemical pharmacology, 86(9), 1328-1337 (2013-09-03)
Hyperuricemia, excess of uric acid in the blood, is a clinical problem that causes gout and is also considered a risk factor for cardiovascular disease. The enzyme xanthine oxidase (XO) produces uric acid during the purine metabolism; therefore, discovering novel...
Jian-Wei Gao et al.
Journal of pharmacological sciences, 115(1), 36-44 (2010-12-17)
DJ-1 was identified as a causal gene for a familial form of early onset Parkinson's disease (PD), park 7. DJ-1 plays roles in transcriptional regulation and the anti-oxidative stress reaction. In this study, we found that protocatechuic aldehyde (PAL), a...
Zhi-Qiang Chang et al.
Journal of nutritional science and vitaminology, 57(1), 118-122 (2011-04-23)
Although various biological activities of Phellinus gilvus (PG) have been reported, the active compounds responsible for these effects are not known. Here, we evaluated the activity of various solvent extracts of PG, and found the ethyl acetate extract (Fd) to...
Yuqin Li et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(11), 1466-1470 (2012-07-12)
A simple and sensitive capillary electrophoresis method with field-enhanced stacking concentration for the analysis of protocatechuic aldehyde, protocatechuic acid, danshensu, rosmarinic acid and salvianolic acid B in Salvia miltiorrhiza var. miltiorrhiza f. alba was developed. The separation was achieved with...
Ya-Ling Xing et al.
Phytotherapy research : PTR, 26(9), 1334-1341 (2012-02-03)
Apoptosis of vascular endothelial cells results in the loss of endothelial integrity, and is a risk factor of atherosclerosis (AS). Lipopolysaccharide (LPS) stimulates inflammation during AS. The current study examined the effect of a potent water-soluble antioxidant, protocatechuic aldehyde (PCA;...
Farid Khallouki et al.
Journal of medicinal food, 14(11), 1397-1402 (2011-08-30)
The root bark of Annona cuneata Oliv. is traditionally used in the Democratic Republic of Congo to treat several debilitating conditions, such as hernia, female sterility, sexual asthenia, and parasitic infections. However, little is known about the composition of the...
Yun-Jing Zhang et al.
Journal of ethnopharmacology, 136(1), 129-136 (2011-04-30)
To evaluate the pharmacokinetics of phenolic compounds after oral administration of Danshen extract in rat brain. Blood and brain microdialysis probes were inserted into jugular vein and cerebral cortex of rat under anesthesia and perfused with ringer's solution at the...
Jeong Rak Lee et al.
Archives of biochemistry and biophysics, 564, 203-210 (2014-12-03)
Protocatechualdehyde (PCA) is one of the important compounds found in barley, green cavendish bananas and grapevine leaves. PCA shows anti-cancer activities in breast, leukemia and colorectal cancer cells. Previous study reported that PCA exerts anti-cancer activity through down-regulating cyclin D1...
Kedan Chu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 35(13), 1699-1701 (2010-09-25)
To develop an HPLC method for gradient elution determination of danshensu and protocatechuic aldehyde in Shengkangling granula. The analysis was carried on a column of Hypersil ODS2-C18 with a mobile phase consisted of methanol-1% glacial acetic acid 0-8 min (5:95)...
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