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Vikrant Rachakonda et al.
Alcoholism, clinical and experimental research, 38(11), 2712-2721 (2014-11-26)
Dysregulated adipose tissue metabolism has been implicated in the pathogenesis of alcoholic liver disease in murine models. We aimed to characterize serum markers of adipose tissue metabolism and inflammation in patients with severe acute alcoholic hepatitis (AAH) and determine their
Yongchun Liu et al.
Environmental science & technology, 46(20), 11112-11118 (2012-09-12)
Heterogeneous uptake of methylamine (MA), dimethylamine (DMA), and trimethylamine (TMA) onto citric acid and humic acid was investigated using a Knudsen cell reactor coupled to a quadrupole mass spectrometer at 298 K. Acid-base reactions between amines and carboxylic acids were
Chongyang Huang et al.
Journal of proteome research, 12(1), 537-545 (2012-12-14)
Cyadox is an antibiotic drug and has the potential to be used as a feedstuff additive in promoting the growth of animals. However, the toxicity of cyadox should be fully assessed before application, and this has prompted the current investigation
E D Ehrenpreis et al.
Journal of clinical gastroenterology, 33(1), 36-40 (2001-06-22)
D-Xylose absorption testing is a simple, low-cost method of screening for small intestinal malabsorption. The optimum method to measure D-xylose absorption (serum vs. urine testing) is uncertain. We present a method of improving the accuracy of D-xylose testing. Fifty-one consecutive
Lokesh Padhye et al.
Environmental science & technology, 45(10), 4353-4359 (2011-04-21)
Interactions of ozone with organic precursors during water treatment may generate carcinogenic N-nitrosodimethylamine (NDMA) byproduct. This study investigates the reaction mechanisms responsible for NDMA formation from ozonation of the commonly used poly(diallyldimethylammonium chloride) (polyDADMAC) coagulant. Upon ozonation, polyDADMAC yields the
H G Wahl et al.
Journal of chromatography. A, 847(1-2), 117-125 (1999-08-04)
A multipurpose sampler (Gerstel MPS), designed for liquid large volume, gaseous and headspace samples was used for the GC-MS analysis of organic volatiles in human urine. Headspace sampling with a volume-, temperature- and speed-controlled gas-tight syringe was combined with a
Yangxi Chu et al.
Physical chemistry chemical physics : PCCP, 17(30), 19789-19796 (2015-07-15)
Alkyl aminium sulfates (AASs) can affect the physicochemical properties of atmospheric aerosols such as hygroscopicity. Previous laboratory experiments have shown that the water content in AAS bulk solutions is higher than in aqueous ammonium sulfate solution in the range of
C L Hoppel et al.
The American journal of physiology, 243(2), E168-E172 (1982-08-01)
The urinary excretion of acetylcarnitine was studied in patients with diabetic ketosis before and during insulin therapy and in normal-weight and obese subjects during fasting. In the diabetic ketotic patients, acetylcarnitine represented 61% of the total acylcarnitine excretion. During the
R E Ostlund et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(21), 9988-9992 (1993-11-01)
D-chiro-inositol is a rare inositol isomer present in inositol phosphoglycans which are proposed mediators of insulin action. To study D-chiro-inositol metabolism in diabetes mellitus, a sensitive and specific assay was developed using negative-ion chemical ionization gas chromatography/mass spectrometry. Median urinary
Chih-Kuang Chuang et al.
Clinica chimica acta; international journal of clinical chemistry, 364(1-2), 209-216 (2005-08-10)
The high prevalence of protein-energy malnutrition is a critical issue for patients with end stage renal disease (ESRD) on hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD). Levels of plasma and intracellular amino acids are significant indicators of protein metabolism
Junli Zhu et al.
Journal of the science of food and agriculture, 92(12), 2436-2442 (2012-04-11)
Trimethylamine oxide (TMAO) in squid is demethylated to dimethylamine (DMA) and formaldehyde (FA) during storage and processing. This study examined the effects of thermal processing and various chemical substances on FA and DMA formation in squid. The thermal conversion of
C S Shin et al.
Diabetes care, 24(4), 733-737 (2001-04-24)
The production of reactive oxygen species is increased in diabetic patients, especially in those will poor glycemic control. We have investigated oxidative damage in type 2 diabetic patients using serum 8-hydroxyguanine (8-OHG) as a biomarker. We studied 41 type 2
Ferdi A Van Dorsten et al.
Journal of agricultural and food chemistry, 54(18), 6929-6938 (2006-08-31)
The purpose of this study was to compare the effects of black and green tea consumption on human metabolism. Seventeen healthy male volunteers consumed black tea, green tea, or caffeine in a randomized crossover study. Twenty-four-hour urine and blood plasma
J Jankowski et al.
The Journal of clinical investigation, 112(2), 256-264 (2003-07-17)
NO prevents atherogenesis and inflammation in vessel walls by inhibition of cell proliferation and cytokine-induced endothelial expression of adhesion molecules and proinflammatory cytokines. Reduced NO production due to inhibition of either eNOS or iNOS may therefore reinforce atherosclerosis. Patients with
Marcus A Bain et al.
Current drug metabolism, 7(7), 811-816 (2006-11-01)
L-Carnitine has important roles in intermediary metabolism and patients with end-stage renal disease who are undergoing hemodialysis may develop a secondary L-carnitine deficiency. The extent of accumulation of the metabolites trimethylamine and trimethylamine-N-oxide when L-carnitine is administered orally has not
Beata Wzorek et al.
Journal of breath research, 4(2), 026002-026002 (2011-03-09)
Biogenic amines are interesting compounds which may be of use for medical diagnosis or therapeutic monitoring. The present paper deals with the problems that occur with concentration determination of dimethylamine (DMA) and trimethylamine (TMA). These occur in the breath of
Kathleen M Dungan et al.
Diabetes care, 29(6), 1214-1219 (2006-05-30)
Postprandial hyperglycemia is often inadequately assessed in diabetes management. Serum 1,5-anhydroglucitol (1,5-AG) drops as serum glucose rises above the renal threshold for glucose and has been proposed as a marker for postprandial hyperglycemia. The objective of this study is to
H F Galley et al.
British journal of anaesthesia, 86(4), 578-580 (2001-09-28)
Nitric oxide synthase requires tetrahydrobiopterin for its activity. In animal models of sepsis, changes in circulating tetrahydrobiopterin concentrations precede increases in nitrate. We measured plasma tetrahydrobiopterin and nitrate concentrations on three consecutive days in 10 patients with septic shock and
Gerhild Zauner et al.
Biochimica et biophysica acta, 1820(9), 1420-1428 (2011-08-02)
Analysis of protein glycosylation is an important first step towards establishing the functions of glycans in health and disease. In contrast to N-glycans which are generally enzymatically released for analysis, there is no corresponding enzyme for O-glycan liberation. Therefore, O-glycans
Mae Sheikh-Ali et al.
Diabetes care, 31(4), 643-647 (2008-01-11)
Current criteria for the diagnosis of diabetic ketoacidosis (DKA) are limited by their nonspecificity (serum bicarbonate [HCO(3)] and pH) and qualitative nature (the presence of ketonemia/ketonuria). The present study was undertaken to determine whether quantitative measurement of a ketone body
Christian Fleck et al.
Clinica chimica acta; international journal of clinical chemistry, 336(1-2), 1-12 (2003-09-23)
NO synthesis is inhibited by the dimethylarginine (DMA) ADMA, which accumulates, similar to SDMA, in the plasma of patients suffering from chronic renal failure (CRF). ADMA and possibly SDMA contribute to hypertension and atherosclerosis in patients with chronic renal disease:
Robert C Tasker et al.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 6(4), 405-411 (2005-06-29)
To explore whether the carbon dioxide-bicarbonate (P(CO(2))-HCO(3)) buffering system in blood and cerebrospinal fluid (CSF) in diabetic ketoacidosis should influence the approach to ventilation in patients at risk of cerebral edema. Medline search, manual search of references in articles found
R Paniagua et al.
Nephron, 69(2), 147-150 (1995-01-01)
Patients with chronic renal failure often have low plasma zinc (Zn) levels. Some factors that may account for abnormal Zn metabolism in these patients are low dietary Zn intake, a specific Zn transport defect, or absence of intestinal Zn ligand.
T Takagi et al.
Journal of chromatography, 272(2), 279-285 (1983-02-11)
The levels of putrescine, cadaverine, spermidine and spermine in uremic plasma were determined with an automatic polyamine analyzer with a 7.5 X 0.2 cm I.D. cation-exchange column using a stepwise sodium chloride gradient. All four polyamines were higher in ten
G A Giussi et al.
Acta diabetologica latina, 16(2), 105-110 (1979-04-01)
Estriol serum levels, neonatal vitality and stromal villous edema were studied in diabetic pregnancies. The average serum estriol levels in diabetic patients whose placentas had villous edema was 26.45 +/- 9.16 ng/ml. This value was significantly lower than that of
Yasuhiro Horita et al.
Bioorganic & medicinal chemistry letters, 19(22), 6313-6316 (2009-10-16)
A series of sugar derivatives (1-13) were synthesized and evaluated for antibacterial activity against Mycobacteriumtuberculosis (MTB), especially multi-drug resistant (MDR) MTB, and the structure-activity relationships of these compounds were studied. The results showed that the compound OCT313 (2-acetamido-2deoxy-beta-D-glucopyranosyl N,N-dimethyldithiocarbamate) (4)
S C Mitchell et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(5), 1734-1738 (2008-02-20)
Forty-six different foods eaten by six healthy male volunteers were investigated as potential sources of the aliphatic secondary amine, dimethylamine. None that were representatives from the fruit and vegetable, meat, dairy and grain produce categories afforded any measurable elevation in
Meric Selbes et al.
Water research, 47(2), 945-953 (2012-12-15)
N-nitrosodimethylamine (NDMA), a probable human carcinogen, is a disinfection by-product that has been detected in chloraminated and chlorinated drinking waters and wastewaters. Formation mechanisms and precursors of NDMA are still not well understood. The main objectives of this study were
A Costa et al.
Metabolism: clinical and experimental, 51(3), 372-375 (2002-03-12)
High uric acid concentration is a common finding in subjects with risk factors for cardiovascular disease (CVD), including some characteristics of the metabolic syndrome. However, its exact role in this setting and in the progression to type 2 diabetes mellitus
Peter I Nagy
Physical chemistry chemical physics : PCCP, 14(2), 849-857 (2011-11-24)
Monte Carlo simulations have been performed for characterizing the 0.22 and 1 molar aqueous dimethylammonium chloride solutions at p = 1 atm and T = 310 K. On the basis of potential of mean force curves for the two systems
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