Showing 1-28 of 28 results for "40993"
Paternal exposures: altered sex ratios.
J Trasler
Teratology, 62(2), 77-78 (2000-08-10)
S Teramoto et al.
Mutation research, 221(1), 1-9 (1989-07-01)
1,2-Dibromo-3-chloropropane (DBCP) is a nematocide, which has been used extensively as a soil fumigant in agriculture. Since sterility was found among male workers involved in the manufacture of DBCP, great concern has been focused on the genetic hazards of DBCP....
Jinwook Chung et al.
Biodegradation, 18(2), 199-209 (2006-07-06)
We tested the hypothesis that the H(2)-based membrane biofilm reactor (MBfR) is capable of reducing multiple oxidized contaminants, a common situation for groundwater contamination. We conducted bench-scale experiments with three groundwater samples collected from California's San Joaquin Valley and on...
Jonathan Hofmann et al.
International journal of occupational and environmental health, 12(4), 321-328 (2006-12-16)
The nematocide 1,2-dibromo-3-chloropropane (DBCP), widely used in Costa Rica during the late 1960s and 1970s, causes sterility in men and is a possible carcinogen. Mortality among a cohort of Costa Rican banana plantation workers was investigated. The cohort included 40,959...
Report on carcinogens : carcinogen profiles, 11, III81-III82 (2004-01-01)
Report on carcinogens : carcinogen profiles, 10, 79-80 (2004-08-25)
[Evidence of toxic effect of a chemical on reproduction ignored].
Maria Albin et al.
Lakartidningen, 106(37), 2296-2297 (2009-10-13)
T Bosma et al.
Applied and environmental microbiology, 65(10), 4575-4581 (1999-10-03)
Trihalogenated propanes are toxic and recalcitrant organic compounds. Attempts to obtain pure bacterial cultures able to use these compounds as sole carbon and energy sources were unsuccessful. Both the haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 (DhlA) and that from Rhodococcus...
Marvin L Meistrich et al.
Toxicological sciences : an official journal of the Society of Toxicology, 76(2), 418-426 (2003-09-30)
The exposure of men to the nematocide dibromochloropropane (DBCP) has caused prolonged oligo- and azoospermia, which occasionally reverses spontaneously. We recently demonstrated that in testes of rats treated with a dose of DBCP sufficient to reduce the percentage of tubules...
Jae-Chun Ryu et al.
Mutagenesis, 17(4), 301-307 (2002-07-12)
1,2-Dibromo-3-chloropropane (DBCP), a soil fumigant against nematodes, has been extensively studied for genotoxicity, carcinogenicity and damage to male reproduction-related organs, as a possible endocrine disruptor. However, the precise mechanisms involved in DBCP-induced mutagenesis and carcinogenesis are as yet unknown. Thus...
Heather A Clark et al.
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews, 23(2), 215-260 (2005-11-18)
Dibromochloropropane (1,2-dibromo-3-chloropropane, DBCP), a pesticide used widely for over 20 years to control nematodes on crops, turf and in nurseries, was banned by the United States Environmental Protection Agency (US EPA) in 1977 because of evidence of infertility in men...
M S Legator
International journal of occupational and environmental health, 5(3), 241-241 (1999-08-11)
Juraj Lábaj et al.
Nutrition and cancer, 57(2), 209-215 (2007-06-19)
The aim of our investigation was to verify the protective effect of lignin on DNA in rat hepatocytes damaged by 3 different genotoxins attacking DNA in a different manner. Hydrogen peroxide was used for induction of direct single strand breaks...
R Sass
International journal of health services : planning, administration, evaluation, 30(3), 491-514 (2000-12-08)
The poisoning of Costa Rican banana workers by multinational corporations' excessive use of pesticides is not a local issue; it is embedded in a dominant ideology expressed by the phenomenon of globalization. This ideology seeps into every aspect of our...
D T Teitelbaum
International journal of occupational and environmental health, 5(2), 122-126 (1999-05-20)
The accumulating data demonstrating the reproductive toxicity of 1, 2-dibromo-3-chloropropane (DBCP) are reviewed. The sentinel event was the discovery of infertility in male pesticide manufacturing workers. In spite of early evidence of testicular damage, first in laboratory animals and later...
Daniel Albert et al.
Arthritis and rheumatism, 51(4), 656-664 (2004-08-31)
To investigate the possibility that environmental agents contribute to the pathogenesis of Wegener's granulomatosis (WG). We undertook an extensive search for possible environmental exposures by developing a comprehensive questionnaire that was administered by telephone interview to 53 patients with WG...
P B Hoyer
Biochemical pharmacology, 62(12), 1557-1564 (2002-01-05)
During the 20th century, there has been an increased risk from environmental by-products that may be harmful to reproductive function in humans. Therefore, as the 21st century begins, it is appropriate to evaluate future directions within the field of reproductive...
L K Lowry et al.
International journal of occupational and environmental health, 5(2), 135-141 (1999-05-20)
Many developed countries permit the export of pesticides that are banned, restricted, or unregistered within their own borders. This practice, which leads to the exposure of agricultural workers in developing countries to high levels of pesticides that are not permitted...
Report on carcinogens : carcinogen profiles, 12, 134-135 (2011-08-20)
Marvin L Meistrich et al.
Reproductive toxicology (Elmsford, N.Y.), 17(3), 263-271 (2003-05-22)
Exposure to the nematocide dibromochloropropane (DBCP) has caused prolonged oligo- and azoospermia in men. There are questions regarding the cellular targets resulting in this effect. In this study we characterized an animal model, in which four daily injections of DBCP...
IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 2, 479-500 (1999-09-07)
Mithat Bakoğlu et al.
Journal of occupational health, 46(2), 156-164 (2004-04-20)
A study was conducted to evaluate the health impact of airborne pollutants on incinerator workers at IZAYDAS Incinerator, Turkey. Ambient air samples were taken from two sampling points in the incinerator area and analyzed for particulate matter, heavy metals, volatile...
Gary S Koe et al.
Biotechnology progress, 21(4), 1119-1127 (2005-08-06)
Cytochromes P450 are known to exhibit diverse catalytic functions against a large number of hydrocarbon substrates. The determinants of specific activity(ies) that operate on specific substrates have not been widely explored. Earlier, we showed that dehalogenation of 1,2-dibromo-3-chloropropane (DBCP) by...
Unwelcome exposure.
Tim Rogers
Lancet (London, England), 364(9439), 1025-1026 (2004-09-24)
Robert H Foote
Reproductive toxicology (Elmsford, N.Y.), 16(6), 749-755 (2002-10-29)
Treatment of protozoal pathogens in the reproductive system with chemical agents exposes flagellated sperm cells to potential toxicants. A widely used antiprotozoal agent is metronidazole. Its effect on rabbit and human sperm was compared with a more soluble 5-nitroazole compound...
S Benoff et al.
Andrologia, 32(4-5), 317-329 (2000-10-06)
Zinc and lead concentrations were measured in seminal plasma from fertile donors, infertile men with varicocoele and men undergoing work-ups for in vitro fertilization. Ejaculated spermatozoa from these subjects were incubated in vitro with various metal ions and/or dibromoethane and...
DBCP in global context: the unchecked power of multinational corporations.
J LaDou
International journal of occupational and environmental health, 5(2), 151-153 (1999-05-20)
Arnaud D Roth et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 28(3), 466-474 (2009-12-17)
Mutations within the KRAS proto-oncogene have predictive value but are of uncertain prognostic value in the treatment of advanced colorectal cancer. We took advantage of PETACC-3, an adjuvant trial with 3,278 patients with stage II to III colon cancer, to...

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