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Showing 1-30 of 33 results for "434507" within Papers
Svetlana V Pavlukhina et al.
ACS applied materials & interfaces, 4(9), 4708-4716 (2012-08-23)
We developed a highly efficient, biocompatible surface coating that disperses bacterial biofilms through enzymatic cleavage of the extracellular biofilm matrix. The coating was fabricated by binding the naturally existing enzyme dispersin B (DspB) to surface-attached polymer matrices constructed via a
Shigeo Takemura et al.
Journal of pharmaceutical sciences, 102(9), 3128-3135 (2013-03-06)
The aim of this study was to find out polymeric compounds that can inhibit the interaction between YM466, a novel anticoagulant, and bile to improve its oral bioavailability. In vitro ultrafiltration method using extract gall powder was useful to detect
Eun-Ho Song et al.
Biomaterials, 33(28), 6889-6897 (2012-07-10)
Targeting cell populations via endogenous carbohydrate receptors is an appealing approach for drug delivery. However, to be effective, this strategy requires the production of high affinity carbohydrate ligands capable of engaging with specific cell-surface lectins. To develop materials that exhibit
Pengcheng Du et al.
Colloids and surfaces. B, Biointerfaces, 102, 1-8 (2012-09-22)
The magnetic-targeting stimuli-responsive hollow polymeric microspheres show unique performance as the intelligent carriers for the site specific controlled delivery of drugs or genes. In the work, the well-defied dual-responsive double-walled hollow microspheres with movable magnetic cores were prepared from the
Qiangying Yi et al.
Langmuir : the ACS journal of surfaces and colloids, 28(29), 10822-10829 (2012-06-27)
Microcapsules composed of weak polyelectrolytes modified with UV-responsive benzophenone (BP) groups were fabricated by the layer-by-layer (LbL) technique. Being exposed to UV lights, capsules shrunk in the time course of minutes at irradiation intensity of 5 mW/cm(2). The shrinkage adjusted
Liqiang Huang et al.
Journal of colloid and interface science, 405, 171-182 (2013-06-13)
Cross-linked chitosan (CCS) microspheres tethered with pH-sensitive poly(methacrylic acid) (PMAA) brushes were developed for the efficient removal of Cd(II) ions from aqueous solutions. Functional PMAA brushes containing dense and active carboxyl groups (COOH) were grafted onto the CCS microsphere surface
Gary Dunderdale et al.
Langmuir : the ACS journal of surfaces and colloids, 28(36), 12955-12961 (2012-08-16)
In this Article, we show that inclined silicon surfaces patterned with poly(methacrylic acid) brushes are able to control the position and movement of 20 μm silica particles, which are propelled across the patterned surface by sedimentation forces. Three different types
Keita Kondo et al.
International journal of pharmaceutics, 453(2), 523-532 (2013-06-26)
We attempted to prepare sustained release fine particles using a two-step mechanical powder processing method; particle-shape modification and dry particle coating. First, particle shape of bulk drug was modified by mechanical treatment to yield drug crystals suitable for the coating
Mingzhi Dai et al.
Analytica chimica acta, 738, 27-34 (2012-07-14)
Two ordered, soft-templated mesoporous carbon powders with cubic and hexagonal framework structure and four different commercial, low cost methacrylate-based polymer binders with widely varying physical properties are investigated as screen printed electrodes for glucose sensors using glucose oxidase and ferricyanide
Ye-Zi You et al.
Methods in molecular biology (Clifton, N.J.), 948, 121-132 (2012-10-17)
Bioreducible polycations, which possess disulfide linkages in the backbone, have appeared as promising gene delivery carriers due to their high stability in extracellular physiological condition and bioreduction-triggered release of genetic materials, as well as reduced cytotoxicity because intracellular cytosol is
Jeremy Lee et al.
Journal of chromatography. A, 1270, 162-170 (2012-11-28)
We introduce a chromatography method for purification of large proteins and viruses that works by capturing them at a non-reactive hydrophilic surface by their mutual steric exclusion of polyethylene glycol (PEG). No direct chemical interaction between the surface and the
T S Anirudhan et al.
Journal of environmental radioactivity, 116, 141-147 (2012-11-17)
The use of a carboxylate-functionalized graft copolymer (PGTDC-COOH) based on titanium dioxide-densified cellulose (TDC) for the removal and recovery of thorium(IV) [Th(IV)] from industrial wastewater is reported in this paper. Infrared spectroscopy and X-ray diffractometer were used to characterize the
Erik C Gunther et al.
Cell reports, 26(1), 145-158 (2019-01-04)
Cellular prion protein (PrPC) binds the scrapie conformation of PrP (PrPSc) and oligomeric β-amyloid peptide (Aβo) to mediate transmissible spongiform encephalopathy (TSE) and Alzheimer's disease (AD), respectively. We conducted cellular and biochemical screens for compounds blocking PrPC interaction with Aβo.
Alireza Shalviri et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(3), 587-597 (2012-09-22)
This work investigated the capability of a new nanoparticulate system, based on terpolymer of starch, polymethacrylic acid and polysorbate 80, to load and release doxorubicin (Dox) as a function of pH and to evaluate the anticancer activity of Dox-loaded nanoparticles
Loredana Ricciardi et al.
Dalton transactions (Cambridge, England : 2003), 41(36), 10923-10925 (2012-08-14)
The grafting of a 2-picolylamine Pt(II) complex into polymethacrylic acid has been successfully performed. The obtained polymer is water soluble, and it represents the first example of a platinum-containing polymer able to photogenerate singlet oxygen.
Stefaan J Soenen et al.
ACS nano, 6(7), 5767-5783 (2012-06-05)
The in vitro labeling of therapeutic cells with nanoparticles (NPs) is becoming more and more common, but concerns about the possible effects of the NPs on the cultured cells are also increasing. In the present work, we evaluate the effects
Alireza Shalviri et al.
Colloids and surfaces. B, Biointerfaces, 101, 405-413 (2012-09-27)
This work focused on the design of new pH-responsive nanoparticles for controlled delivery of anticancer drug doxorubicin (Dox). Nanoparticles of poly(methacrylic acid)-polysorbate 80-grafted starch (PMAA-PS 80-g-St) were synthesized by using a one-pot method that enabled simultaneous grafting of PMAA and
Naila Mebarek et al.
International journal of pharmaceutics, 454(2), 611-620 (2013-06-25)
Poly(methacrylic acid)-b-poly(ethylene oxide) are double hydrophilic block copolymers, which are able to form micelles by complexation with a counter-polycation, such as poly-l-lysine. A study was carried out on the ability of the copolymers to interact with model membranes as a
Caihong Zhou et al.
The Analyst, 137(19), 4469-4474 (2012-08-08)
An inverse opal photonic crystal sensor that could specifically detect chloramphenicol (CAP) in a label-free way was introduced in the current research. A colloidal crystal template was first prepared from monodisperse SiO(2) nanospheres. Precursors with different compositions were infused into
Shivaan Cooppan et al.
Pharmaceutical development and technology, 18(5), 1066-1077 (2012-05-18)
This study aimed at developing double crosslinked isoniazid (INH)-loaded polymethyl-methacrylate-ethylcellulose (PMMA-EC) polyspheres for rate-controlled enteric drug delivery. A PMMA solution was manipulated with the addition of EC to produce polyspheres by drop-wise extrusion into a primary crosslinking solution of AlCl3
Alper Akkaya et al.
Preparative biochemistry & biotechnology, 43(1), 48-59 (2012-12-12)
Poly(3-hydroxybutyrate) is nontoxic and biodegradable, with good biocompatibility and potential support for long-term implants. For this reason, it is a good support for enzyme immobilization. Enzyme immobilization could not be done directly because poly(3-hydroxybutyrate) has no functional groups. Therefore, modification
Pavel Jandera et al.
Journal of chromatography. A, 1274, 97-106 (2013-01-01)
We synthesized 8 polymethacrylate monolithic capillary columns using laurylmethacrylate functional monomer and various cross-linking monomers differing in the polarity and size. The efficiency of monolithic columns for low-molecular compounds significantly improved with increasing number of repeat non-polar methylene groups in
Wataru Takada et al.
Analytical biochemistry, 435(2), 123-130 (2013-01-22)
Glycosaminoglycans (GAGs) take part in numerous biological processes by binding to protein molecules and functionally regulating protein-ligand interactions; therefore, molecular interactions of GAGs have been studied by several methods, including surface plasmon resonance, enzyme-linked immunosorbent assays (ELISAs), and GAG microarrays.
Yuan-Jia Pan et al.
Biomaterials, 33(27), 6570-6579 (2012-06-19)
A new type of redox/pH dual stimuli-responsive poly(methacrylic acid) (PMAA)-based nanohydrogels was prepared from methacrylic acid and N,N-bis(acryloyl)cystamine crosslinker via distillation-precipitation polymerization. The nanohydrogels could be easily degraded into individual linear short chains (M(n) ≈ 1200, M(w)/M(n) < 1.1) in
Toshiyuki Kida et al.
Langmuir : the ACS journal of surfaces and colloids, 28(43), 15378-15384 (2012-10-02)
Isotactic poly(methyl methacrylate) (it-PMMA)/syndiotactic poly(methacrylic acid) (st-PMAA) stereocomplex hollow capsules were fabricated by the deposition of stereocomplex films of it-PMMA and st-PMAA on silica particles by alternate layer-by-layer assembly and the subsequent removal of the silica particles with aqueous HF.
Cemil Aydoğan et al.
Journal of separation science, 35(8), 1010-1016 (2012-05-17)
Polymethacrylate-based monolith with weak cation exchange functionalities was prepared in capillary column (i.d. 100 μm, o.d. 375 μm) by in situ polymerization of butyl methacrylate, ethylene dimethacrylate and N-methacryloyl-L-glutamic acid in presence of porogens. The porogen mixture included N,N-dimethyl formamide
Xuetuan Wei et al.
Applied biochemistry and biotechnology, 168(7), 1753-1764 (2012-09-19)
This study presents a novel and integrated preparation technology for nattokinase functional food, including strain screening, fermentation, separation, and encapsulation. To rapidly screen a nattokinase-productive strain, PCR-based screening method was combined with fibrinolytic activity-based method, and a high productive strain
Ania Servant et al.
Advanced healthcare materials, 2(6), 806-811 (2012-11-28)
Drug release triggered by an external non-invasive stimulus is of great interest for the development of new drug delivery systems. The preparation of an electroresponsive multiwalled carbon nanotube/poly(methylacrylic acid) (MWNT/PMAA)-based hybrid material is reported. The hydrogel hybrids achieve a controlled
Fei Tian et al.
Optics letters, 37(20), 4299-4301 (2012-10-18)
The cladding air channels of an endlessly single-mode photonic crystal fiber (PCF) and the high-index sensitivity of its long-period gratings (LPG) inscribed by CO(2) laser have been exploited to deposit poly(vinyl pyrrolidone) (PVPON)/poly(methacrylic acid) (PMAA) polyelectrolyte thin films via layer-by-layer
Magda Staňková et al.
Journal of chromatography. A, 1289, 47-57 (2013-04-11)
We synthesized seven different polymethacrylate monolithic capillary columns using N,N-dimethyl-N-metacryloxyethyl-N-(3-sulfopropyl) ammonium betaine functional monomer (MEDSA) and various cross-linking monomers differing in the polarity and size. The efficiency of monolithic columns for polar low-molecular compounds in the aqueous normal-phase (HILIC) mode
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