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437549

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Adi Dror et al.
Applied microbiology and biotechnology, 99(22), 9449-9461 (2015-06-01)
Enzymatic production of biodiesel by transesterification of triglycerides and alcohol, catalyzed by lipases, offers an environmentally friendly and efficient alternative to the chemically catalyzed process while using low-grade feedstocks. Methanol is utilized frequently as the alcohol in the reaction due
Nan-Wei Wan et al.
Journal of biotechnology, 214, 27-32 (2015-09-12)
A halohydrin dehalogenase (HHDH-PL) from Parvibaculum lavamentivorans DS-1 was characterized and applied to determine azide and cyanide in the water. In this methodology, HHDH-PL catalysed azide and cyanide to react with butylene oxide and form corresponding β-substituted alcohols 1-azidobutan-2-ol (ABO)
Chen-Hsi Hsieh et al.
BMC cancer, 15, 316-316 (2015-05-01)
5-fluorouracil (5-FU) is employed to enhance radiotherapy (RT) effect. Here, we evaluated the influence of whole-pelvic irradiation on the pharmacokinetics (PK) of 5-FU in plasma and lymphatic system of rats as the experimental model. RT with 2 Gy was delivered to
Joe O Boison et al.
Analytical and bioanalytical chemistry, 407(14), 4065-4078 (2015-04-03)
A new multi-residue method for the determination of seven polypeptides, namely, polymixin B1, polymixin B2, polymixin E1 (colistin A), polymixin E2 (colistin B), enduracidin A (enramycin A), enduracidin B (enramycin B), and bacitracin A, in food of animal origin was
Aimin Qiao et al.
Fitoterapia, 98, 137-142 (2014-08-05)
Sour jujube is a common fruit and traditional medicine in China. Bioactivity-guided fractionation of sour jujube was used to determine the chemical identity of potent antiproliferative and antioxidant constituents. Four novel ursane-type triterpenoids, together with 8 known were isolated and
Joong-Seok Min et al.
Lipids in health and disease, 14, 77-77 (2015-07-24)
Cholesterol oxidation products (COPs) are produced during thermal processing of animal origin foods and are considered to have negative health impacts. The model systems are helpful to understand the impact of various factors on oxidation changes in foods during cooking
Hana Stiborova et al.
The Science of the total environment, 533, 439-445 (2015-07-17)
Disposal of solid waste to landfills from waste water sewage treatment plants (WWTPs) serves as a potential source of contamination by polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCD). Native microbial communities have been found to degrade a variety of xenobiotics
Magdalena Golasik et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 28(3), 338-343 (2014-05-29)
Chronic exposure even to low doses of manganese may lead to development of neurological syndrome similar to parkinsonism. The aim of this research is to assess the possibility of manganese poisoning based on the level of metal in the urine
Soohyun Cho et al.
Meat science, 108, 44-49 (2015-05-31)
This study investigated the effect of slaughter age on the antioxidant enzyme activity, lipid and protein oxidation, and color stability in striploins (M. longissimus lumborum) from Korean Hanwoo (Bos taurus coreanae) cows of different age groups (1.9 to 3.7, 4.0
Aarón de la Cerda-Carrasco et al.
Journal of the science of food and agriculture, 95(7), 1521-1527 (2014-08-02)
Phenolic compounds are widely distributed secondary metabolites in plants usually conferring them with unique taste, flavour and health-promoting properties. In fruits of Vitis vinifera L., phenolic composition is highly dependent on grape variety. Differential extraction of these compounds from grapes
Majid Afshari et al.
Natural product research, 29(14), 1300-1306 (2015-01-09)
In this study, the combined effect of pH, temperature and agitation speed on yellow pigment production and mycelial growth of Penicillium aculeatum ATCC 10409 was investigated in whey media. Different pH levels (5, 6.5 and 8), temperatures (25, 30 and
Nrupa Borkar et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 89, 216-223 (2014-12-17)
Apomorphine, a subcutaneously administered drug for Parkinson's disease with short half-life requires frequent administration leading to patient non-compliance. This study aimed at synthesising and purifying lipophilic diesters of apomorphine, and investigating their in vitro degradation in biorelevant media before and
Valeria Ferretti et al.
Molecular pharmaceutics, 12(5), 1501-1511 (2015-03-21)
Co-crystals are crystalline complexes of two or more molecules bound together in crystal lattices through noncovalent interactions. The solubility and dissolution properties of co-crystals can allow to increase the bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). It is currently
Fuchao Xu et al.
Journal of chromatography. A, 1401, 33-41 (2015-05-23)
A multi-residue analytical method was developed for the determination of a range of flame retardants (FRs), including polybrominated diphenyl ethers (PBDEs), emerging halogenated FRs (EFRs) and organophosphate FRs (PFRs), in food matrices. An ultrasonication and vacuum assisted extraction (UVAE), followed
M Kosová et al.
Journal of clinical pharmacy and therapeutics, 40(4), 436-440 (2015-05-28)
Parabens have been commonly used as preservatives in pharmaceutical and cosmetics industries for almost 50 years. These compounds are thermostable, pH-stable and inexpensive and have a wide antimicrobial effect. The antimicrobial activity of parabens in emulsion system is limited by
Ines van Dooren et al.
Journal of ethnopharmacology, 169, 69-75 (2015-04-12)
Infusions of Herniaria hirsuta L., Herniaria glabra L. and Herniaria fontanesii J.Gay are well known in Moroccon folk medicine for the treatment of biliary dyskinesia, (uro)lithiasis or as a diuretic. Herniariae Herba which can contain H. glabra and H. hirsuta
María Cordero-Vaca et al.
Analytical and bioanalytical chemistry, 407(16), 4615-4627 (2015-05-01)
Four different crosslinked polymeric ionic liquid (PIL)-based sorbent coatings were evaluated in an automated direct-immersion solid-phase microextraction method (automated DI-SPME) in combination with gas chromatography (GC). The crosslinked PIL coatings were based on vinyl-alkylimidazolium- (ViCnIm-) or vinylbenzyl-alkylimidazolium- (ViBzCnIm-) IL monomers
Xavier Matabosch et al.
Drug testing and analysis, 7(8), 663-672 (2014-12-30)
Glucocorticosteroids are prohibited in sports when administered by systemic routes and allowed using other administrations for therapeutic reasons. Therefore, markers to distinguish between routes of administration through the analysis of urine samples are needed in anti-doping control. As a first
Christina O'Rourke et al.
Annals of botany, 116(2), 225-236 (2015-06-27)
During evolution, plants have acquired and/or lost diverse sugar residues as cell-wall constituents. Of particular interest are primordial cell-wall features that existed, and in some cases abruptly changed, during the momentous step whereby land-plants arose from charophytic algal ancestors. Polysaccharides
John Suberu et al.
Journal of pharmaceutical and biomedical analysis, 117, 522-531 (2015-10-18)
An improved liquid chromatography-tandem mass spectrometry (LC-MS/MS) protocol for rapid analysis of co-metabolites of A. annua in raw extracts was developed and extensively characterized. The new method was used to analyse metabolic profiles of 13 varieties of A. annua from
Zareen S Khan et al.
Journal of chromatography. A, 1418, 228-232 (2015-10-04)
Public exposure to pesticide residues through the main/side-stream smoke of tobacco (Nicotiana tabacum L.) is an international concern. This article reports optimization and validation of large-scale multiresidue analysis methods involving low pressure and traditional gas chromatography tandem mass spectrometry in
Hannelore Rücker et al.
Organic & biomolecular chemistry, 13(10), 3040-3047 (2015-01-27)
Inflammatory signaling pathways orchestrate the cellular response to infection and injury. These pathways are known to be modulated by compounds that alkylate cysteinyl thiols. One class of phytochemicals with strong thiol alkylating activity is the chalcones. In this study we
Nadia Malek Saied et al.
European journal of medicinal chemistry, 97, 280-288 (2015-05-21)
The goal of this study is to develop a novel brain receptor imaging agent. This study reports the synthesis, characterization and the biological evaluation of 1-((2-methoxyphenyl) piperazine)ferrocenecarboxamide labeled with technetium-99 m ((99m)Tc-MP). The (99m)Tc-MP was obtained quickly (radiolabelling time < 5 min), in 90%
Yang Yang et al.
Inorganic chemistry, 54(12), 5839-5854 (2015-05-23)
A series of monomeric zinc silylamido complexes bearing [NNNO]-type tetradentate aminophenolate ligands, LZnN(SiMe3)2 [L = {(2-R(1))ArCH2N[(CH2)2R(2)]CH2(4-R(4)-6-R(3))C6H2O-}, R(1) = NMe2, R(2) = N(i)Pr2, R(3) = R(4) = Cl (1), R(3) = R(4) = cumyl (3); R(1) = NMe2, R(2) = NEt2
Benito F García et al.
Molecules (Basel, Switzerland), 20(11), 20079-20106 (2015-11-13)
The citrus by-products released from citrus processing plants may contain high levels of potentially bioactive compounds such as flavonoids, which are a widely distributed group of polyphenolic compounds with health-related properties based on their antioxidant activity. In the study reported
Thi Van Anh Ha et al.
Food chemistry, 178, 115-121 (2015-02-24)
Lycopene nanoemulsions were prepared to protect the antioxidant activity and improve the bioaccessibility of lycopene-enriched tomato extract (containing 6% of lycopene) by an emulsification-evaporation method. Lycopene nanoemulsions, with droplet sizes between 100 and 200 nm, exhibited higher anti-radical efficiency and
Pierina Visciano et al.
Journal of food protection, 78(9), 1719-1728 (2015-09-01)
Concentrations of pollutants with regulatory limits were determined in specimens of Chamelea gallina, a species of clam collected along the Abruzzi coastal region of the central Adriatic Sea. Nine sampling sites were selected to evaluate the distribution of contaminants in
Haitao Huang et al.
Colloids and surfaces. B, Biointerfaces, 133, 362-369 (2015-07-06)
In this study, a novel micellar drug carrier was fabricated from an amphiphilic diblock copolymer containing poly (ethylene glycol) monomethyl ether (mPEG) and stearic moiety (C18) with a linkage of valine-citrulline (VC), which can be cleaved by cathepsin B (CB)
Julio César España Amórtegui et al.
Food chemistry, 182, 14-22 (2015-04-07)
The most relevant parameters of a multimode inlet were optimized to increase the injection volume up to 25 μL using solvent vent mode in order to improve the sensitivity of the gas chromatography-mass spectrometry system. Consequently, the implementation of a
Vanessa Cardeñosa et al.
Molecules (Basel, Switzerland), 20(5), 8287-8302 (2015-05-12)
Five sweet orange (Citrus sinensis Osbeck) varieties cultivated in Huelva (Spain) and picked at two seasons during two consecutive years, were characterized for their antioxidant activity (free radicals scavenging activity, reducing power and lipid peroxidation inhibition) and vitamin content (vitamin
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