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Courtney Dunn et al.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 19(5), 504-509 (2012-05-19)
Therapies exist for acute organophosphate (OP) exposure but mortality rates remain high (10% to 20%). Currently, treatment focuses on reversing the resultant cholinergic excess effects through the use of atropine. Intralipid fat emulsion (IFE) has been used to treat lipophilic...
Inactivation of rat liver cytochrome P-450 by the suicide substrates parathion and chloramphenicol.
J Halpert et al.
Drug metabolism reviews, 12(2), 239-259 (1981-01-01)
Steven B Bird et al.
Toxicology, 247(2-3), 88-92 (2008-04-02)
Organophosphorus (OP) pesticides poison more than 3,000,000 people every year in the developing world, mostly through intentional self-poisoning. Advances in medical therapy for OP poisoning have lagged, and current treatment is not highly effective with mortality of up to 40%...
Meha Jaiswal et al.
Environmental science and pollution research international, 19(6), 2055-2062 (2012-01-05)
Removal of malathion from agricultural runoff was studied using novel copper-coated chitosan nanocomposite (CuCH)-a biopolymeric waste obtained from marine industry. Synthesis and characterization of the adsorbent using different spectral techniques like Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy, energy-dispersive...
F Laynez Bretones et al.
Medicina clinica, 108(6), 224-225 (1997-02-15)
A case of family food poisoning by the organophosphate insecticide (OPI) parathion is revised. Poisoning was involuntary, affecting four brothers in one family that ate eggplant floured with parathion, which was mistaken for flour. As a result, 2 patients died...
Jing Liu et al.
Toxicology and applied pharmacology, 272(3), 608-615 (2013-08-13)
Parathion (PS) and chlorpyrifos (CPF) are organophosphorus insecticides (OPs) that elicit acute toxicity by inhibiting acetylcholinesterase (AChE). Endocannabinoids (eCBs, N-arachidonoylethanolamine, AEA; 2-arachidonoylglycerol, 2AG) can modulate neurotransmission by inhibiting neurotransmitter release. We proposed that differential inhibition of eCB-degrading enzymes (fatty acid...
Yu Zhang et al.
Applied and environmental microbiology, 78(18), 6647-6655 (2012-07-17)
The phosphotriesterase-like lactonase (PLL) enzymes in the amidohydrolase superfamily hydrolyze various lactones and exhibit latent phosphotriesterase activities. These enzymes serve as attractive templates for in vitro evolution of neurotoxic organophosphates (OPs) with hydrolytic capabilities that can be used as bioremediation...
Caridad López-Granero et al.
Toxicological sciences : an official journal of the Society of Toxicology, 131(1), 206-216 (2012-09-19)
Exposure to organophosphates (OPs) can lead to cognitive deficits and oxidative damage. Little is known about the relationship between behavioral deficits and oxidative stress within the context of such exposures. Accordingly, the first experiment was carried out to address this...
Seyed Mortaza Robatjazi et al.
Biotechnology letters, 35(1), 67-73 (2012-09-22)
Magnetically-modified Sphingomonas sp. was prepared using covalent binding of magnetic nanoparticles on to the cell surface. The magnetic modified bacteria were immobilized in the fixed-bed bioreactors (FBR) by internal and external magnetic fields for the biodetoxification of a model organophosphate...
Anna Bojanowska-Czajka et al.
Journal of AOAC International, 95(5), 1378-1385 (2012-11-28)
The decomposition of the widely used organophosphorus pesticide parathion was carried out in aqueous solutions by the use of gamma-irradiation from a 60Co source or ozonation by means of an ozone generator, and by combined processes of ozonation and radiolysis....
Can mild organophosphate poisoning result in myocardial infarction?
Hossein Sanaei-Zadeh
Journal of forensic and legal medicine, 19(6), 363-363 (2012-08-01)
Chunya Li et al.
Colloids and surfaces. B, Biointerfaces, 90, 152-158 (2011-11-08)
Parathion imprinted polymer beads were prepared by free radical polymerization using parathion as template, methacrylic acid as functional monomer, divinyl benzene as cross-linking reagent and 2,2'-azobis(isobutyronitrile) as initiator. The obtained molecularly imprinted beads were characterized with transmission electron micrograph. The...
Parathion: residues in soil and water.
N Sethunathan et al.
Residue reviews, 68, 91-122 (1977-01-01)
Attilio Naccarato et al.
Food chemistry, 206, 67-73 (2016-04-05)
This work proposes the novel PDMS/DVB/PDMS fiber as a greener strategy for analysis by direct immersion solid phase microextraction (SPME) in vegetables. SPME is an established sample preparation approach that has not yet been adequately explored for food analysis in...
Yi H Liu et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 47(5), 475-483 (2012-03-20)
The effectiveness of homologous and heterologous formats in a nanocolloidal gold-based immunoassay for pesticide residue determination was investigated. Parathion, one of the most toxic organophosphorus pesticides, was used as the target analyte. One-step homologous and heterologous test strips based on...
Th Zilker
Deutsche medizinische Wochenschrift (1946), 139(1-2), 31-46 (2014-01-07)
Ingestion of household products and plants are the leading cause for calls to the poison control centres as far as children are involved. Severe intoxication in children has become infrequent due to childproofed package and blister packs for drugs. Chemical...
Issam Ben Salem et al.
Food chemistry, 141(2), 1398-1405 (2013-06-25)
The γ-irradiation effects on polyphenolic content and antioxidant capacity of parathion-pretreated leaves of Salvia officinalis plant were investigated. The analysis of phenolic extracts of sage without parathion showed that irradiation decreased polyphenolic content significantly (p<0.05) by 30% and 45% at...
Organ donation following fatal organophosphate poisoning.
Jean-Louis Mariage et al.
Transplant international : official journal of the European Society for Organ Transplantation, 25(6), e71-e72 (2012-03-27)
Rania Ibrahim et al.
International journal of pharmaceutics, 435(1), 33-37 (2012-04-10)
A previously developed method employing the use of a dialysis membrane in series with human dermis tissue mounted in side-by-side diffusion cells was utilized to observe the effects of the presence of soluble proteins in the donor compartment on the...
Residues of parathion, methyl parathion, EPN, and their oxons in Canadian fruits and vegetables.
D E Coffin
Residue reviews, 7, 61-73 (1964-01-01)
Jerry Yen et al.
Neurotoxicology and teratology, 33(6), 735-741 (2011-11-01)
Zebrafish are increasingly used for developmental neurotoxicity testing because early embryonic events are easy to visualize, exposures are done without affecting the mother and the rapid development of zebrafish allows for high throughput testing. We used zebrafish to examine how...
Kamyar Ahmadi et al.
Talanta, 137, 167-173 (2015-03-17)
Ultrasound leaching-solid phase extraction (USL-SPE) followed by dispersive-solidification liquid-liquid microextraction (DSLLME) was developed for preconcentration and determination of organophosphorus pesticides (OPPs) in soil samples prior gas chromatography-mass spectrometry analysis. At first, OPPs were ultrasonically leached from soil samples by using...
Reza Ahmadkhaniha et al.
TheScientificWorldJournal, 2012, 627607-627607 (2012-05-31)
A reliable and sensitive headspace solid-phase microextraction gas chromatography-mass spectrometry method for simultaneous determination of different organophosphorus pesticides in dried medicinal plant samples is described. The analytes were extracted by single-walled carbon nanotubes as a new solid-phase microextraction adsorbent. The...
Heleni Tsoukali et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 822(1-2), 194-200 (2005-07-02)
Headspace-solid phase microextraction (HS-SPME) was studied and optimised for the determination of four common organophosphorus pesticides (OPPs) in biological samples. Various parameters controlling SPME were studied: choice of SPME fiber, type and content of salt added, preheating and extraction time...
Changgeng Liu et al.
Chemosphere, 87(5), 470-476 (2012-01-10)
Organophosphorus pesticides (OPPs) emit into the atmosphere in both gas and particulate phases via spray drift from treatments and post-application emission, but most of their degradations in the atmosphere are not well known. In this study, the heterogeneous reactions of...
Shan Jin et al.
Journal of biomolecular screening, 18(1), 108-115 (2012-09-11)
Organophosphates are a class of highly toxic chemicals that includes many pesticides and chemical weapons. Exposure to organophosphates, either through accidents or acts of terrorism, poses a significant risk to human health and safety. Existing antidotes, in use for over...
Florian Eyer et al.
Toxicological reviews, 22(3), 143-163 (2004-06-09)
The mortality rate of suicidal parathion poisoning is particularly high, the onset of fulminant cholinergic signs, and the patients frequently present to the emergency physician with life-threatening symptoms. Despite this uniformity, subsequent clinical course differs significantly among patients, mostly not...
Ana Masiá et al.
Journal of chromatography. A, 1345, 86-97 (2014-05-06)
Ultra-high pressure liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QqTOF-MS) acquiring full scan MS data for quantification, and automatic data dependent information product ion spectra (IDA-MS/MS) without any predefinition of the ions by the user was checked for identifying organic contaminants in...
Becky J Proskocil et al.
American journal of physiology. Lung cellular and molecular physiology, 304(8), L519-L529 (2013-02-05)
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of functional loss of inhibitory M2 muscarinic receptors...
Alejandro A Canales-Aguirre et al.
Nutritional neuroscience, 15(2), 62-69 (2012-02-16)
One of the main concerns regarding organophosphate pesticides (OP) is their possible toxic effects. Doses that do not produce acute toxicity are capable of altering the structure and biochemistry of different tissues and organs by production of reactive oxygen species...
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