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D A King et al.
Journal of animal science, 90(7), 2410-2423 (2012-07-07)
The potential interaction of growth-promoting implants and genetic markers previously reported to be associated with growth, carcass traits, and tenderness was evaluated. Two implant protocols were applied to subsets of steers (n = 383) and heifers (n = 65) that
María-Esther Cruz et al.
Alcoholism, clinical and experimental research, 38(6), 1611-1621 (2014-05-14)
Intragastric or intraperitoneal ethanol (EtOH) treatment inhibits reproductive functions in females and male rats. The area of the hypothalamus where these effects take place is unknown. As the participations of the preoptic-anterior hypothalamic area (POA-AHA) in regulating ovulation is asymmetric
Shilpa Bharti et al.
Fertility and sterility, 99(1), 140-148 (2012-09-25)
To investigate the antiestrogenic effect of clomiphene citrate (CC) in male rats estrogenized with estradiol-3-benzoate (EB). Prospective experimental study. Laboratory. Adult male albino rats (Holtzman strain). CC was given alone or in combination with EB. Testicular function and steroidogenic enzyme
Kenichiro Watanabe et al.
The Journal of endocrinology, 219(3), 269-278 (2013-10-11)
Urocortin 2 (Ucn2) is a member of the corticotropin-releasing factor peptide family and is expressed by various tissues, including reproductive tissues such as the uterus, ovary, and placenta. However, the regulatory mechanisms of Ucn2 expression and the physiological significance of
Brian P Kenealy et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(49), 19051-19059 (2013-12-07)
Release of gonadotropin releasing hormone (GnRH) from the medial basal hypothalamus (MBH)/median eminence region (S-ME) is essential for normal reproductive function. GnRH release is profoundly regulated by the negative and positive feedback effects of ovarian estradiol (E2). Here we report
Jessica L Bolton et al.
Behavioural processes, 90(3), 415-419 (2012-05-15)
The present study investigated the preference of prepubescent and adult rats for an unrelated conspecific over a closely related conspecific (e.g., father, mother). Preference was measured by the amount of time spent in the vicinity of the stimulus animals as
Kara J Connelly et al.
Endocrinology, 156(1), 193-202 (2014-10-21)
Peak bone mass, one of the most important predictors for fracture risk later in life, is attained during puberty and adolescence and influenced by neonatal and pubertal sex-specific gonadal hormones and GH-IGF-I secretion patterns. This study examined the effects of
Jesús Olayo-Lortia et al.
The journal of sexual medicine, 11(10), 2428-2438 (2014-07-24)
The multiple partner choice arena (MPCA) is an experimental setup in which male rats display a significant shortening of ejaculation latency, which is the main characteristic of premature ejaculation (PE) in men. Thus, the MPCA is a potential animal model
C M Martins et al.
Theriogenology, 78(5), 974-980 (2012-07-24)
Two experiments evaluated the effects of timing of the induction of ovulation in superstimulated lactating Holstein donor cows that were fixed-time artificially inseminated. Secondary objectives were to evaluate the effects of the timing of progesterone (P4) device removal (Experiment 1)
Jessica Santollo et al.
Behavioural brain research, 191(2), 173-177 (2008-05-03)
Available data suggest that estradiol exerts an inhibitory effect on food intake by modulating the actions of multiple gut- and brain-derived peptides implicated in the control of food intake. For example, recent studies have shown that estradiol decreases the orexigenic
Ravindranath Reddy Gilibili et al.
Toxicological sciences : an official journal of the Society of Toxicology, 140(1), 26-39 (2014-04-23)
There is a growing body of evidence that exposure to endocrine disrupting chemicals and to estrogenic compounds in particular can affect the testis and male fertility. In the present study, the constitutive expression of steroidogenic and non-steroidogenic cytochrome P450 (CYP)
R M Cleale et al.
Journal of animal science, 90(13), 5056-5066 (2012-10-27)
Synovex Plus (SP) is a product that delivers 28 mg of estradiol benzoate (EB) and 200 mg of trenbolone acetate (TBA). We studied the impact of a polymeric, porous coating on SP implants (CSP) to prolong release of EB and
Hanne M Hoffmann et al.
Endocrinology, 155(10), 4043-4053 (2014-07-26)
The known genetic causes of idiopathic hypogonadotropic hypogonadism (IHH) are often associated with the loss of GnRH neurons, leading to the disruption of the hypothalamic pituitary gonadal axis and subfertility. The majority of IHH cases have unknown origins and likely
Chandra Suma J Miryala et al.
The journal of sexual medicine, 10(2), 350-361 (2012-11-01)
The selective serotonin reuptake inhibitor (SSRI), fluoxetine, leads to sexual dysfunction in a substantial proportion of women. In studies with the Fischer inbred rat, the 5-HT(1A) receptor has been implicated in this sexual dysfunction. Whether this association with 5-HT(1A) receptors
R M Cleale et al.
Journal of animal science, 91(2), 970-977 (2013-01-12)
Trials were conducted with beef heifers at 4 sites to evaluate feedlot performance and carcass characteristics in response to implants containing 14 mg estradiol benzoate and 100 mg trenbolone acetate (EB/TBA; Synovex Choice, Zoetis LLC, New York, NY), 14 mg
T Kawarasaki et al.
Journal of animal science, 90(13), 4781-4787 (2012-07-26)
In the present study, we investigated the influence of exogenous estrogen on embryo survival after transfer into prepubertal gilts in which estrus had been induced. In the first experiment, estrus was induced in prepubertal gilts by the administration of 1,000
Damian G Zuloaga et al.
Endocrinology, 153(9), 4432-4443 (2012-07-11)
Although several studies have reported the localization of membrane progesterone (P(4)) receptors (mPR) in various tissues, few have attempted to describe the distribution and regulation of these receptors in the brain. In the present study, we investigated expression of two
Kazunaga Oshima et al.
The Journal of veterinary medical science, 74(11), 1469-1475 (2012-07-13)
The reproductive performance of postpartum cows is affected by factors such as suckling and nutrition. We investigated the effect of a restricted suckling period on the superovulatory response and the fertility after flushing in postpartum Japanese Black cows. Forty-seven postpartum
Tatsuyuki Yoshida et al.
Animal science journal = Nihon chikusan Gakkaiho, 83(7), 529-534 (2012-07-11)
This study was designed to evaluate the effect of estrus synchronization treatments on recipient heifers for embryo transfer (ET). Holstein heifers were separated into the following three groups: (i) an administration of 50 µg GnRH (gonadotropin-releasing hormone) analog was given
Vinícius G Pinheiro et al.
Theriogenology, 79(5), 797-802 (2013-01-17)
The objective was to evaluate when the LH reserve was re-established in postpartum Nellore (Bos indicus) cows by evaluating the response of the hypothalamic-pituitary axis responsiveness to exogenous GnRH or estradiol benzoate (EB). Additionally, we tested the influence of dietary
Xiaoliang Qiu et al.
Endocrinology, 154(3), 1337-1348 (2013-02-09)
Pubertal onset only occurs in a favorable, anabolic hormonal environment. The neuropeptide kisspeptin, encoded by the Kiss1 gene, modifies GnRH neuronal activity to initiate puberty and maintain fertility, but the factors that regulate Kiss1 neurons and permit pubertal maturation remain
Keiko Arakawa et al.
Neuroendocrinology, 100(2-3), 162-177 (2014-10-11)
Exposure to stressors such as foot shock (FS) leads to increased expression of multiple inflammatory factors, including the proinflammatory cytokine interleukin-1 (IL-1) in the brain. Studies have indicated that there are sex differences in stress reactivity, suggesting that the fluctuations
S A A Edwards et al.
Animal reproduction science, 137(3-4), 129-136 (2013-02-05)
The aim of this study was to investigate the effects on follicle stimulating hormone (FSH) secretion and dominant follicle (DF) growth, of treatment of Bos indicus heifers with different combinations of intra-vaginal progesterone releasing devices (IPRD), oestradiol benzoate (ODB), PGF2α
Lynda Uphouse et al.
Pharmacology, biochemistry, and behavior, 122, 16-19 (2014-03-22)
A brief restraint experience reduces lordosis behavior in ovariectomized females that have been hormonally primed with estradiol benzoate. The addition of progesterone to the priming prevents the lordosis inhibition. Based on prior studies with an inhibitor of progesterone metabolism, we
Matthew Mahavongtrakul et al.
Endocrinology, 154(9), 3251-3260 (2013-07-05)
Sexual receptivity in the female rat is dependent on dose and duration of estradiol exposure. A 2 μg dose of estradiol benzoate (EB) primes reproductive behavior circuits without facilitating lordosis. However, 50 μg EB facilitates lordosis after 48 hours. Both
B Ariyadi et al.
Poultry science, 92(12), 3205-3213 (2013-11-16)
Mucins play an essential role as mucosal barrier to prevent invasion of pathogens in the oviductal tissue of hens. The aim of this study was to determine the effect of estradiol and lipopolysaccharide (LPS) on the mucin expression in the
Baher A Ibrahim et al.
Journal of neuroscience research, 91(9), 1226-1238 (2013-07-05)
This study investigated the hypothesis that estrogen controls hindbrain AMP-activated protein kinase (AMPK) activity and regulation of blood glucose, counterregulatory hormone secretion, and hypothalamic nerve cell transcriptional status. Dorsal vagal complex A2 noradrenergic neurons were laser microdissected from estradiol benzoate
Deena M Walker et al.
Endocrinology, 154(6), 2129-2143 (2013-04-18)
Polychlorinated biphenyls (PCBs) are industrial contaminants and known endocrine-disrupting chemicals. Previous work has shown that gestational exposure to PCBs cause changes in reproductive neuroendocrine processes. Here we extended work farther down the life spectrum and tested the hypothesis that early
J N S Sales et al.
Theriogenology, 78(3), 510-516 (2012-04-17)
The effects of estradiol benzoate (EB) and estradiol cypionate (EC) on induction of ovulation after a synchronized LH surge and on fertility of Bos indicus females submitted to timed AI (TAI) were evaluated. In Experiment 1, ovariectomized Nelore heifers were
L M Pompei et al.
Climacteric : the journal of the International Menopause Society, 16(1), 147-153 (2012-05-30)
To study the effects of estrogen therapy on the expression of matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) and perlecan in the vascular wall. Twenty 180-day-old Wistar rats were castrated and treated 1 week later for a period of
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