Showing 1-30 of 40 results for "46940-U"
Hiroshi Kitagaki et al.
Journal of bioscience and bioengineering, 117(4), 383-393 (2013-11-12)
Mitochondria are sites of oxidative respiration. During sake brewing, sake yeasts are exposed to long periods of hypoxia; the structure, role, and metabolism of mitochondria of sake yeasts have not been studied in detail. It was first elucidated that the...
Frank Norbert Gellerich et al.
IUBMB life, 65(3), 180-190 (2013-02-13)
This review focuses on problems of the intracellular regulation of mitochondrial function in the brain via the (i) supply of mitochondria with ADP by means of ADP shuttles and channels and (ii) the Ca(2+) control of mitochondrial substrate supply. The...
Duoduo Chen et al.
Molecular microbiology, 87(6), 1237-1244 (2013-01-26)
Nicotine is an environmental toxicant in tobacco waste, imposing a serious hazard for human health. Some bacteria including Pseudomonas spp. strains are able to metabolize nicotine to non-toxic compounds. The pyrrolidine pathway of nicotine degradation in Pseudomonas putida S16 has...
Narendra Kumar Sharma et al.
Journal of proteomics, 79, 277-298 (2013-01-15)
Hypoxia is one of the major stressors at high altitude. Exposure to hypobaric hypoxia induces several adverse consequences to the structural and functional integrity of brain. In an attempt to understand the proteome modulation, we used 2-DE coupled with MALDI-TOF/TOF...
Mengjie Li et al.
American journal of physiology. Renal physiology, 304(11), F1317-F1324 (2013-03-08)
Early diagnosis of diabetic nephropathy (DN) is difficult although it is of crucial importance to prevent its development. To probe potential markers and the underlying mechanism of DN, an animal model of DN, the db/db mice, was used and serum...
Mary-Rus Martínez-Cuenca et al.
Tree physiology, 33(3), 320-329 (2013-03-07)
The effects of iron (Fe) deficiency on the low-molecular-weight organic acid (LMWOA) metabolism have been investigated in Carrizo citrange (CC) [Citrus sinensis (L.) Osb. × Poncirus trifoliata (L.) Raf.] roots. Major LMWOAs found in roots, xylem sap and root exudates were citrate...
Salah Khattab et al.
Gene, 533(1), 313-321 (2013-09-21)
Pilosocereus robinii is a rare species which is experiencing sudden population collapse. Identifying and developing effective conservation and management strategies to halt the forestall extinction of this species is crucial. The present study was conducted to assess the best conditions...
Sonia Osorio et al.
Plant physiology, 161(2), 628-643 (2012-12-20)
The aim of this work was to investigate the effect of decreased cytosolic phosphoenolpyruvate carboxykinase (PEPCK) and plastidic NADP-dependent malic enzyme (ME) on tomato (Solanum lycopersicum) ripening. Transgenic tomato plants with strongly reduced levels of PEPCK and plastidic NADP-ME were...
Pham Huynh Ninh et al.
Applied and environmental microbiology, 79(6), 1996-2001 (2013-01-22)
The heat treatment of recombinant mesophilic cells having heterologous thermophilic enzymes results in the denaturation of indigenous mesophilic enzymes and the elimination of undesired side reactions; therefore, highly selective whole-cell catalysts comparable to purified enzymes can be readily prepared. However...
Cintia Lucía Arias et al.
Plant molecular biology, 81(3), 297-307 (2012-12-18)
Arabidopsis thaliana is a plant species that accumulates high levels of organic acids and uses them as carbon, energy and reducing power sources. Among the enzymes that metabolize these compounds, one of the most important ones is malic enzyme (ME)....
Haiyan Ding et al.
Environmental monitoring and assessment, 186(2), 1123-1131 (2013-10-08)
As a result of natural processes and human activities, aluminum (Al) toxicity is recognized as a major limiting factor for plant productivity, and the secretion of organic acids facilitated by channel proteins is one of the most important Al resistance...
A Ruhal et al.
Cellular and molecular biology (Noisy-le-Grand, France), 58(1), 15-20 (2013-01-01)
An amperometric malic acid biosensor was developed by immobilizing malate dehydrogenase on multi-walled carbon nanotubes (MWCNT) coated on screen printed carbon electrode. The screen printed carbon electrode is made up of three electrodes viz., carbon as working, platinum as counter...
Bhavana Agrawal et al.
The Journal of biological chemistry, 288(10), 7351-7362 (2013-01-17)
Mitochondria are important targets of metal toxicity and are also vital for maintaining metal homeostasis. Here, we examined the potential role of mitochondria in homeostasis of nickel in the roots of nickel hyperaccumulator plant Alyssum murale. We evaluated the biochemical...
Siva S V P Sakamuri et al.
GeroScience, 40(3), 347-356 (2018-06-04)
Mitochondria play a critical role in the cardiomyocyte physiology by generating majority of the ATP required for the contraction/relaxation through oxidative phosphorylation (OXPHOS). Aging is a major risk factor for cardiovascular diseases (CVD) and mitochondrial dysfunction has been proposed as...
José María Landete et al.
Applied and environmental microbiology, 79(18), 5509-5518 (2013-07-10)
Lactobacillus casei is the only lactic acid bacterium in which two pathways for l-malate degradation have been described: the malolactic enzyme (MLE) and the malic enzyme (ME) pathways. Whereas the ME pathway enables L. casei to grow on l-malate, MLE...
Ie E Koliesnikova et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 59(3), 58-64 (2013-08-21)
The results of pharmacological correction of experimental mitochondrial dysfunction in brain stem neurons after single injection of specific respiratory complex I inhibitor rotenone by complex agents mildronate and rhytmocor have been presented. It was shown that 14-days rhytmocor injection promoted...
Mark Mapstone et al.
Nature medicine, 20(4), 415-418 (2014-03-13)
Alzheimer's disease causes a progressive dementia that currently affects over 35 million individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no cures or disease-modifying therapies, and this may be due to our inability...
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Christoph Knuf et al.
Applied and environmental microbiology, 79(19), 6050-6058 (2013-07-31)
Malic acid has great potential for replacing petrochemical building blocks in the future. For this application, high yields, rates, and titers are essential in order to sustain a viable biotechnological production process. Natural high-capacity malic acid producers like the malic...
Neusa Martins et al.
Plant science : an international journal of experimental plant biology, 198, 1-6 (2012-12-04)
We investigated the effect of Al (400μM) on organic acids secretion, accumulation and metabolism in Plantago almogravensis Franco and Plantago algarbiensis Samp. Al induced a significant reduction on root elongation only in P. algarbiensis. Both species accumulated considerable amounts of...
Zhi-Peng Wang et al.
Bioresource technology, 143, 674-677 (2013-07-09)
In this study, after screening of 9 fungal strains for their ability to produce calcium malate, it was found that Penicillium sclerotiorum K302 among them could produce high-level of calcium malate. Under the optimal conditions, the titer of calcium malate...
Bo Liang et al.
Environmental toxicology and pharmacology, 35(2), 154-160 (2013-01-19)
In this study, the mitochondria from the livers of Siganus fuscessens were exposed to the Irgarol-1051with or without respiratory chain inhibitors using succinate or malate as the substrate, and the effects on mitochondrial ROS production were tested. The mitochondrial ROS...
Qi-Chun Zhang et al.
Phytotherapy research : PTR, 28(5), 722-727 (2013-08-06)
Our previous investigation had confirmed the inhibition of platelet aggregation of a novel Corni fructus-derived formula composed of malic acid, succinic acid and citric acid with a ratio of 3:2:2. The present study was to further evaluate the anti-thrombotic effect...
Rafael Moreno-Sánchez et al.
The FEBS journal, 280(3), 927-938 (2012-12-05)
Succinate-driven oxidation via complex II (CII) may have a significant contribution towards the high rates of production of reactive oxygen species (ROS) by mitochondria. Here, we show that the CII Q site inhibitor thenoyltrifluoroacetone (TTFA) blocks succinate + rotenone-driven ROS...
Mahvash Zakikhani et al.
PloS one, 7(11), e49513-e49513 (2012-11-28)
KU-55933 is a specific inhibitor of the kinase activity of the protein encoded by Ataxia telangiectasia mutated (ATM), an important tumor suppressor gene with key roles in DNA repair. Unexpectedly for an inhibitor of a tumor suppressor gene, KU-55933 reduces...
Agnieszka Nawirska-Olszańska et al.
Food chemistry, 148, 415-419 (2013-11-23)
The aim of the research was to determine the composition of organic acids in fruit of different cultivars of three pumpkin species. The amount of acids immediately after fruit harvest and after 3 months of storage was compared. The content...
Mark B Taylor et al.
Journal of drugs in dermatology : JDD, 12(1), 45-50 (2013-02-05)
Treatment of melasma and postinflammatory hyperpigmentation is often challenging. No ideal short-term and long-term treatment is available. Vitamin C alone and in combination with iontophoresis has been studied and found to be useful; however, no long-term studies have been published....
Ali Guney et al.
Waste management (New York, N.Y.), 33(9), 1795-1799 (2013-06-12)
Plastics have become the widely used materials because of their advantages, such as cheapness, endurance, lightness, and hygiene. However, they cause waste and soil pollution and they do not easily decompose. Many promising technologies are being investigated for separating mixed...
D Novoa-Díaz et al.
Ultrasonics, 54(6), 1575-1580 (2014-05-06)
The progress of malolactic fermentation in red wines has been monitored by using ultrasonic techniques. The evolution of ultrasonic velocity of a tone burst 1MHz longitudinal wave was measured, analyzed and compared to those parameters of oenological interest obtained simultaneously...
O Iu Velykopols'ka et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 84(5), 76-88 (2013-01-25)
Using Clark oxygen electrode, dependence of mitochondrial functions on Ca(2+)-release channels activity of Chironomus plumosus L. larvae salivary glands suspension was investigated. Cells were ATP-permeabilized in order to enable penetration of exogenous oxidative substrates. Activation of plasmalemmal P2X-receptors (as well...

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