José-Ángel García-Pedraza et al.
Clinical and experimental pharmacology & physiology, 42(6), 640-647 (2015-04-10)
5-HT is a powerful vasoconstrictor substance in renal vasculature (mainly by 5-HT₂ activation). Nevertheless, 5-HT is notable for its dual cardiovascular effects, producing both vasodilator and vasoconstrictor actions. This study aimed to investigate whether, behind the predominant serotonergic vasoconstrictor action