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Liuyang Zhang et al.
Scientific reports, 5, 18108-18108 (2015-12-09)
Carbon-based substrates offer unprecedented advantages in lightweight supercapacitors. However, it is still challenging to achieve high coverage or loading. Different from the traditional belief that a lack of defects or functional groups is the cause of poor growth on carbon-based
Jin Qu et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33(4), 468-474 (2015-01-23)
The purpose of the current study was to develop a novel technology to enhance tendon-to-bone interface healing by trypsinizing and mineralizing (TM) an intrasynovial tendon allograft in a rabbit bone tunnel model. Eight rabbit flexor digitorum profundus (FDP) tendons were
Suzan Semaan et al.
CNS neuroscience & therapeutics, 21(2), 164-172 (2014-10-14)
Although compelling evidence suggests that human hypothalamic hamartoma (HH) is intrinsically epileptogenic for gelastic seizures, the molecular mechanisms responsible for epileptogenesis within HH remain to be elucidated. The aim of this study was to test the hypothesis that hyperactivation of
Mohammad I K Hamad et al.
Journal of neuroscience methods, 240, 48-60 (2014-12-03)
Calcium imaging has unraveled the calcium-dependent mechanisms underlying neuronal function. Acetoxymethyl ester (AM) dyes are widely employed for calcium imaging. Pluronic F127 (PF127) as a surfactant and dimethyl sulfoxide (DMSO) as a solvent are used to dissolve the dyes, but
Yuki Kawai et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 28(11), 1029-1031 (2012-11-15)
The tube radial distribution of solvents was observed in an aqueous ionic liquid mixed solution of 1-butyl-3-methylimidazolium chloride fed into a capillary tube. A phase diagram was constructed with 1-butyl-3-methylimidazolium chloride and potassium hydroxide, which included boundary curves between homogeneous
Mary Beth Hall et al.
Journal of microbiological methods, 118, 147-151 (2015-09-22)
Microbial glycogen measurement is used to account for fates of carbohydrate substrates. It is commonly applied to washed cells or pure cultures which can be accurately subsampled, allowing the use of smaller sample sizes. However, the nonhomogeneous fermentation pellets produced
Sebastian Höss et al.
Environmental toxicology and chemistry, 34(11), 2660-2669 (2015-06-03)
The use of colloidal iron oxide (FeOx) in the bioremediation of groundwater contamination implies its increasing release into the environment and requires an assessment of its ecotoxicological risk. Therefore, microcosm experiments were carried out to investigate the impact of ferrihydrite
Tao Dong et al.
Applied microbiology and biotechnology, 99(23), 10237-10247 (2015-08-16)
Accurate determination of fatty acid contents is routinely required in microalgal and yeast biofuel studies. A method of rapid in situ fatty acid methyl ester (FAME) derivatization directly from wet fresh microalgal and yeast biomass was developed in this study.
Marzieh Kamankesh et al.
Meat science, 103, 61-67 (2015-01-27)
A simple and rapid analytical tech nique for the simultaneous determination of 16 polycyclic aromatic hydrocarbons (PAHs) in grilled meat was developed using microwave-assisted extraction and dispersive liquid-liquid microextraction (MAE-DLLME) followed by gas chromatography-mass spectrometry (GC-MS). The effective parameters in
Kazeem D Adeyemi et al.
Journal of animal science and biotechnology, 6, 51-51 (2015-12-05)
Improving the unsaturated fatty acid content of ruminant meat is essential due to the generally saturated nature of fatty acids in ruminant meat and the negative effects this can have on human health. Nonetheless, enhancing the unsaturated fatty acid content
Yu Zhou et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(16), 5237-5242 (2015-04-08)
To probe structure and gating-associated conformational changes in BK-type potassium (BK) channels, we examined consequences of Cd(2+) coordination with cysteines introduced at two positions in the BK inner pore. At V319C, the equivalent of valine in the conserved Kv proline-valine-proline
Hao Hu et al.
Toxicology and applied pharmacology, 289(1), 30-39 (2015-09-08)
Human cytochrome P450 (CYP) 2A6 enzyme has been proposed to play a role in cellular defence against chemical-induced oxidative stress. The encoding gene is regulated by various stress activated transcription factors. This paper demonstrates that p53 is a novel transcriptional
Hassan M Albishri et al.
Journal of chromatographic science, 53(7), 1123-1130 (2014-12-30)
Two cyclodextrin micellar liquid chromatographic methods were developed and applied to the simultaneous determination of bisoprolol/hydrochlorothiazide and atenolol/chlorthalidone combinations in urine matrices without sample pretreatment. These combined β-blockers and diuretics chemotherapies are commonly used in the treatment of hypertension and
In-Seek Jeong et al.
Journal of food science, 77(10), C1042-C1046 (2012-09-18)
In this study, nonheated saponification was employed as a novel, rapid, and easy sample preparation method for the determination of cholesterol in emulsified foods. Cholesterol content was analyzed using gas chromatography with a flame ionization detector (GC-FID). The cholesterol extraction
T P Pirog et al.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 75(3), 32-40 (2013-07-23)
Synthesis of extracellular metabolites with surface-active and emulsifying properties, pH being maintained at the level of 5.8-8.0, in the process of cultivation of Acinetobacter calcoaceticus IMV B-7241 in the medium with ethanol (2%, volume part) was investigated. It is established
Rui Gusmão et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(46), 16474-16478 (2015-10-08)
Fluorographane (C1 Hx F1-x+δ )n is a new member of the graphene family that exhibits hydrophobicity and a large band gap that is tunable based on the level of fluorination. Herein, sensing and energy applications of fluorographane are reported. The
Madhur D Shastri et al.
PloS one, 10(3), e0118798-e0118798 (2015-03-05)
T-cell-mediated inflammatory cytokines, such as interleukin (IL)-4, IL-5, IL-13 and tumor necrosis factor-alpha (TNF-α), play an important role in the initiation and progression of inflammatory airways diseases. Low-molecular-weight heparins (LMWHs), widely used anticoagulants, possess anti-inflammatory properties making them potential treatment
Veronika F S Pape et al.
Journal of inorganic biochemistry, 144, 18-30 (2015-01-16)
Three novel pyrimidinylhydrazones substituted at either the aromatic moiety or at the imine carbon atom were synthesized and characterized by standard analytical methods. All compounds were found to be toxic in the micro- to submicromolar range against a diverse panel
Lesley C Homer et al.
Lab animal, 41(11), 327-335 (2012-10-20)
Alkaline hydrolysis-based tissue dissolvers (TDs) are commercially available tools for the digestion and decontamination of infectious animal waste. The authors carried out a series of experiments to verify whether the TD in their facility completely digested animal carcasses and inactivated
Pilar Viñas et al.
Journal of pharmaceutical and biomedical analysis, 94, 173-179 (2014-03-08)
Capillary liquid chromatography (LC) is used for the determination of tocopherols and tocotrienols in cosmetic products. Dispersive liquid-liquid microextraction (DLLME) allows the analytes to be preconcentrated into a very small volume of organic solvent which is then injected into the
Brian M Smith et al.
Environmental science & technology, 49(21), 12789-12797 (2015-10-08)
Collisions with and attachment to natural colloids (heteroaggregation) is likely to influence significantly the fate, transport, and toxicity of engineered nanoparticles (ENPs). This study investigated heteroaggregation between hematite (α-Fe2O3) colloids and citrate-capped gold nanoparticles (Cit-AuNPs) using a novel approach involving
Chen Wang et al.
Acta pharmacologica Sinica, 36(12), 1451-1461 (2015-11-26)
Neferine is an isoquinoline alkaloid isolated from seed embryos of Nelumbo nucifera (Gaertn), which has a variety of biological activities. In this study we examined the effects of neferine on Kv4.3 channels, a major contributor to the transient outward current
Yuying Suo et al.
Journal of molecular biology, 427(4), 887-900 (2014-12-24)
During export in Escherichia coli, SecB, a homotetramer structurally organized as a dimer of dimers, forms a complex with two protomers of SecA, which is the ATPase that provides energy to transfer a precursor polypeptide through the membrane via the
Evanthia Tambosis et al.
International journal of dermatology, 51(8), 935-938 (2012-07-14)
The cheapest, most rapid method for the diagnosis of mycotic skin and nail infections is direct examination of samples using a KOH preparation. The standard KOH wet mount lacks a color contrast. Various contrast dyes are available. Parker ink is
Javed Iqbal et al.
Toxicology mechanisms and methods, 24(8), 544-551 (2014-07-26)
Advancement in the field of analytical food-chemistry has explored various experimental techniques for aflatoxins (AFs) quantification. The present study was aimed to compare four different techniques; thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), liquid chromatography-tandem mass spectrometry (LC-MS/MS) and enzyme-linked
Jinhui Xu et al.
European journal of drug metabolism and pharmacokinetics, 39(4), 301-310 (2013-12-24)
The extended use of doxorubicin (DOX) could be limited due to the emergence of drug resistance and cardiotoxicity associated with its treatment. Conjugates of DOX with transferrin (DOX-TRF) can effectively alleviate these side effects, thereby leading to a better treatment.
Fabrice Jean-Pierre et al.
Microbiology (Reading, England), 161(9), 1889-1896 (2015-08-25)
RsmA is a post-transcriptional RNA-binding protein that acts as a pleiotropic global regulator of mRNAs in the opportunistic pathogen Pseudomonas aeruginosa. Upon binding to its target, RsmA impedes the translation of the mRNA by the ribosome. The RsmA regulon affects
Mats Wiedemann et al.
Molecules (Basel, Switzerland), 20(10), 19085-19100 (2015-10-23)
The glucose-lowering effects of lupin seeds involve the combined action of several components. The present study investigates the influence of one of the main quinolizidine alkaloids, lupanine, on pancreatic beta cells and in an animal model of type-2 diabetes mellitus.
Casandra R Cox et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(39), 14057-14061 (2014-09-17)
Direct solar-to-fuels conversion can be achieved by coupling a photovoltaic device with water-splitting catalysts. We demonstrate that a solar-to-fuels efficiency (SFE) > 10% can be achieved with nonprecious, low-cost, and commercially ready materials. We present a systems design of a
Kyung Hoon Kim et al.
Small (Weinheim an der Bergstrasse, Germany), 11(46), 6215-6224 (2015-10-21)
Tracking and monitoring the intracellular behavior of mRNA is of paramount importance for understanding real-time gene expression in cell biology. To detect specific mRNA sequences, molecular beacons (MBs) have been widely employed as sensing probes. Although numerous strategies for MB
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