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Shutaro Gunji et al.
Surgery, 154(5), 991-999 (2013-09-07)
Peritoneal carcinomatosis is a poor prognostic factor for patients with gastrointestinal, gynecologic, and pancreatic cancer. Cisplatin (CDDP) is among the most effective anti-cancer agents, although its adverse effects remain unresolved. For the treatment of peritoneal carcinomatosis with high-dose CDDP, it
Raja Mohd Hafidz Raja Nhari et al.
Journal of food science, 77(1), R42-R46 (2012-01-21)
Usage of gelatin in food products has been widely debated for several years, which is about the source of gelatin that has been used, religion, and health. As an impact, various analytical methods have been introduced and developed to differentiate
Johno Breeze et al.
Journal of the Royal Army Medical Corps, 159(2), 84-89 (2013-05-31)
Ballistic gelatin is the most common tissue simulant used to reproduce the penetration of projectiles into muscle but published data to support its use are primarily based on bullets, despite explosive fragments being the most common cause of injury to
Mitsumasa Kawago et al.
The Journal of thoracic and cardiovascular surgery, 147(5), 1644-1649 (2013-09-12)
Intra-airway and intra-arterial administration of gelatin-embedded, sustained-release basic fibroblast growth factor has stimulated regeneration of emphysematous lungs in animal experiments, but these routes of administration may also cause harm. This study investigated the effectiveness of intrapleural administration of gelatin-embedded, sustained-release
Louise Clemmesen et al.
Ugeskrift for laeger, 175(9), 576-578 (2013-04-24)
This article describes the production of a low-cost training phantom for ultrasound guided invasive procedures of peripheral and central veins and presents a video of the process. The phantom can be adapted for use with other ultrasound techniques. It is
Rampurna Prasad Gullapalli
Journal of pharmaceutical sciences, 99(10), 4107-4148 (2010-08-26)
It is estimated that more than 40% of new chemical entities (NCEs) coming out of the current drug discovery process have poor biopharmaceutical properties, such as low aqueous solubility and/or permeability. These suboptimal properties pose significant challenges for the oral
Claudio Schonauer et al.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 13 Suppl 1, S89-S96 (2004-06-29)
The use of local agents to achieve hemostasis is an old and complex subject in surgery. Their use is almost mandatory in spinal surgery. The development of new materials in chemical hemostasis is a continuous process that may potentially lead
Jia-Hua Ma et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 33(5), 602-605 (2008-06-10)
Novel dosage forms emerges more and more in recent years. One of them is liquid-filled hard gelatin capsules, which adopt gelatin or the hydroxypropyl methyl cellulose (HPMC) as capsule shell. The liquid-filled hard gelatin capsule is increasingly getting attention because
T N Golovach et al.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 75(1), 14-20 (2013-03-23)
It is shown, that the producer of exopolysaccharides Xantomonas campestris pv. campestris IMV B-7001 is more sensitive to freeze-drying, than to freezing-thawing and keeps stable morphological properties. Predicted preservation of viability is within the limits of 2-8 years at -70
Motomi Shiono
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 11(1), 19-23 (2008-04-17)
Acute type A aortic dissection is a lethal aortic disease with an extremely poor prognosis unless surgical intervention is performed in a timely manner. Since the clinical introduction of gelatin-resorcin-formalin (GRF) glue in Japan, tear-oriented aortic repairs have been widely
Endoscopic injection of gelatin solution for severe hemorrhagic gastric cancer.
M Tajika et al.
Gastrointestinal endoscopy, 43(3), 247-250 (1996-03-01)
Mark C Jenkins et al.
Avian diseases, 57(3), 622-626 (2013-11-29)
Control of avian coccidiosis is increasingly being achieved by the administration of low doses of Eimeria oocysts to newly hatched chicks. The purpose of this study was to test the efficacy of gel beads containing a mixture of Eimeria acervulina
Paulraj Kanmani et al.
Food chemistry, 148, 162-169 (2013-11-23)
Active nanocomposite films were prepared by blending aqueous solutions of gelatin with different concentrations of silver nanoparticles (AgNPs) using a solvent casting method. Formation of silver nanoparticles in the solution and films was confirmed with the surface plasmon resonance (SPR)
Jun-Lin Chi et al.
Radiation research, 181(4), 416-424 (2014-04-12)
In this study, we investigated the effect of (131)I gelatin microspheres ((131)I-GMSs) on human hepatocellular carcinoma cells (HepG2) in nude mice (Balb/c) and the biodistribution of (131)I-GMSs after intratumoral injection. The treatment group and control group animals received intratumoral injections
Leslie Crews et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(16), 4250-4260 (2008-04-18)
Altered expression and mutations in alpha-synuclein (alpha-syn) have been linked to Parkinson's disease (PD) and related disorders. The neurological alterations in PD patients have been associated with degeneration of dopaminergic cells and other neuronal populations. Moreover, recent studies in murine
Renuka Khatik et al.
Expert opinion on drug delivery, 11(5), 633-646 (2014-03-13)
The principle objective of this study was to develop 1,2-diacyl-sn-glycero-3-phospho-l-serine (PS)-coated gelatin nanoparticles (GNPs) bearing amphotericin B (AmB) for specific targeting to the macrophages involved in visceral leishmaniasis (VL). The two-step desolvation method has been used for the preparation of
M Alizadeh et al.
Materials science & engineering. C, Materials for biological applications, 33(7), 3958-3967 (2013-08-06)
A combined freeze-drying and particulate leaching method for scaffold synthesis showed an improvement in the horizontal microstructure of the gelatin/chitosan scaffolds. Type and concentration of the cross-linking agent, freezing temperature, concentration of the polymeric solution and gelatin/chitosan weight ratio were
Ashley R Flory et al.
BMC biotechnology, 13, 28-28 (2013-03-28)
It is important for industries to find green chemistries for manufacturing their products that have utility, are cost-effective and that protect the environment. The paper industry is no exception. Renewable resources derived from plant components could be an excellent substitute
Chunfeng Zhao et al.
Plastic and reconstructive surgery, 133(5), 628e-637e (2014-01-22)
Using allograft is an attractive alternative for flexor tendon reconstruction because of the lack of donor-site morbidity, and better matching to the intrasynovial environment. The purpose of this study was to use biological lubricant molecules to modify the graft surface
C Whitfield
Journal of the Royal Army Medical Corps, 152(4), 197-201 (2007-05-19)
To date, the specific role of gelatins in trauma resuscitation remains under-investigated. Their adverse affects are well described and relate principally to the provocation of allergic responses whilst their influence upon haemostasis is relatively benign in comparison to the other
Anish Babu et al.
Journal of biomedical nanotechnology, 9(2), 177-192 (2013-05-01)
The present study focused on the development of a novel biodegradable nanoparticle system based on polyethyleneglycol-modified gelatin (PEG-GEL) and polylactic acid (PLA) biopolymers for improving the photodynamic efficacy of cyclohexane-1,2-diamino hypocrellin B (CHA2HB), a potent photodynamic therapeutic (PDT) agent. The
Ivy Kanungo et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2455-2459 (2013-03-19)
The dielectric behavior of the gelatine-GAGs based blend systems has been studied to understand the dynamic behavior of the water at the protein-GAGs interfaces which are relevant for tissue engineering application. Impedance (Z) and phase have been measured as a
Nor Fazliyana Mohtar et al.
Food chemistry, 155, 64-73 (2014-03-07)
Chemical modifications of gelatin from New Zealand hoki (Macruronus novaezelandiae) skins were carried out using three different cross-linking agents, namely, genipin, glutaraldehyde and caffeic acid, at different concentrations. The chemically modified gelatins exhibited better physical properties, such as higher gel
Ayşegül Karataş et al.
Acta poloniae pharmaceutica, 70(5), 883-897 (2013-10-24)
The aim of the study was to investigate the physical stability of the semi-solid dispersions into the hard gelatine capsules prepared with Gelucire 44/14, Labrasol and different additives such as microcrystalline cellulose (MCC), mannitol and lactose (alpha-monohydrate) used for enhancing
Giorgia Imparato et al.
Biomaterials, 34(32), 7851-7861 (2013-07-31)
The realization of thick and viable tissues equivalents in vitro is one of the mayor challenges in tissue engineering, in particular for their potential use in tissue-on-chip technology. In the present study we succeeded in creating 3D viable dermis equivalent
Nur Cebi et al.
Food chemistry, 277, 373-381 (2018-12-07)
Gelatin is widely used in gummy candies because of its unique functional properties. Generally, porcine and bovine gelatins are used in the food industry. FTIR-ATR combined with chemometrics analysis such as hierarchical cluster analysis (HCA) (OPUS Version 7.2 software), principal
Delia Mihaela Iurea et al.
Journal of nanoscience and nanotechnology, 13(6), 3841-3850 (2013-07-19)
New sub-micronic capsules based on a copolymer of maleic anhydride-alt-vinyl acetate and a natural polymer (gelatin) using an interfacial condensation method were obtained. Sub-micronic capsules were characterized by Fourier Transform infrared spectroscopy (FTIR), dynamic light scattering (DLS) method, zeta-potential, scanning
Nao Hiwatashi et al.
The Annals of otology, rhinology, and laryngology, 124(2), 116-125 (2014-08-15)
Treatment of vocal fold scarring remains challenging. We have previously reported the therapeutic effects of local injection of basic fibroblast growth factor (bFGF) in animal models and humans. A novel collagen/gelatin sponge (CGS) is capable of sustained release of bFGF
Łukasz Jerzy Dobrzyński et al.
Polimery w medycynie, 40(2), 11-19 (2010-07-24)
Soft gelatin capsules (Softgels) are modern and effective pharmaceutical dosage form for the administration of many medicinal products and food supplements formulations. In this short article major advantages and disadvantages of soft gelatin capsules are reviewed. Each step of manufacturing
David Olsen et al.
Advanced drug delivery reviews, 55(12), 1547-1567 (2003-11-19)
The tools of recombinant protein expression are now being used to provide recombinant sources of both collagen and gelatin. The primary focus of this review is to discuss alternatives to bovine collagen for biomedical applications. Several recombinant systems have been
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