Showing 1-30 of 121 results for "


Cornelia Vasile et al.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 117(2), 565-571 (2013-12-18)
This paper is a short review on the state-of-the-art of the use of polyelectrolyte complexes containing polysaccharides for wound and burn healing and treatment using the chitosan/hyaluronic acid polyelectrolyte complex (PEC) hydrogel. PEC is suitable for wound healing because a...
Shi Xu et al.
Journal of nanoscience and nanotechnology, 13(1), 129-138 (2013-05-08)
For the purpose of achieving targeted chemotherapy of pancreatic cancer, we prepared core-shell nanoparticles by coaxial electrospray technology, with folate-chitosan as the polymeric coating material and gemcitabine as the encapsulated drug. The effects of various solution properties and processing parameters...
Ya-Lei Zhang et al.
Carbohydrate polymers, 97(2), 809-816 (2013-08-06)
A novel magnetic-molecularly imprinted polymer (MMIP) based on chitosan-Fe₃O₄ has been synthesized for fast separation of carbamazepine (CBZ) from water. During polymerization, the modified chitosan-Fe₃O₄ was used not only as supporter but also as functional monomer. The properties of obtained...
Kido Nwe et al.
Journal of medicinal chemistry, 56(20), 7862-7869 (2013-09-21)
Neoplastic lesions can create a hostile tumor microenvironment with low extracellular pH. It is commonly believed that these conditions can contribute to tumor progression as well as resistance to therapy. We report the development and characterization of a pH-responsive magnetic...
Stephanie Supper et al.
Expert opinion on drug delivery, 11(2), 249-267 (2013-12-07)
Thermogelling chitosan (CS)/glycerophosphate (GP) solutions have been reported as a new type of parenteral in situ forming depot system. These free-flowing solutions at ambient temperature turn into semi-solid hydrogels after parenteral administration. Formulation parameters such as CS physico-chemical characteristics, CS/gelling...
Zhen-Hai Zhang et al.
Journal of biomedical nanotechnology, 9(4), 601-609 (2013-04-30)
N-octyl-N-Arginine chitosan (OACS) was synthesized in an attempt to combine the permeation enhancing effects of arginine-rich peptides and the drug loading capacity of the amphipathic polymers for insulin oral delivery. OACS self-assembled micelles of insulin were prepared by the conventional...
Hajer Aloui et al.
International journal of food microbiology, 170, 21-28 (2013-12-03)
This study reports the efficacy of the combined application of chitosan (CH) and Locust Bean Gum (LBG) in combination with different citrus essential oils (EOs) to inhibit Aspergillus flavus in vitro and on artificially infected dates for a storage period...
Tony Z Jin et al.
Journal of food protection, 76(5), 779-785 (2013-05-07)
This study was conducted to develop antimicrobial coatings to decontaminate and prevent cross-contamination of shell eggs. Egg shells were inoculated with nalidixic acid-resistant Salmonella enterica Enteritidis strains OB030832, OB040159, and C405 and treated with antimicrobial coatings. Polylactic acid served as...
Yuangang Liu et al.
Journal of nanoscience and nanotechnology, 14(5), 3844-3849 (2014-04-17)
Fucoidan was chosen a substitute for alginate in chitosan-based polyelectrolytes or polyiones because it is negatively charged and possesses pharmacological properties. The fucoidan-chitosan nanospheres were prepared by the sonification method, and different formulation variables were investigated to get regular and...
Qinmin Cui et al.
Journal of nanoscience and nanotechnology, 13(6), 3832-3840 (2013-07-19)
Cross-linked chitosan (CS) nanohydrogels were successfully prepared via cross-linking CS nanodroplets in inverse miniemulsions. The cross-linker was transferred to the CS nanodroplets via the evaporation from its aqueous solution and diffusion through the continuous phase. The formation of cross-linked CS...
Jui-Yang Lai et al.
International journal of molecular sciences, 11(12), 5256-5272 (2010-01-01)
The interaction between cells and biopolymers is the evaluation indicator of the biocompatibility of materials. The purpose of this work was to examine the responses of retinal pigment epithelial (RPE) cells to genipin (GP) or glutaraldehyde (GTA) cross-linked chitosan by...
Seyed Mohamad Sadegh Modaresi et al.
Pharmaceutical development and technology, 19(5), 593-597 (2013-07-19)
Chitosan (CS) nanoparticles have been extensively studied as carriers for therapeutic proteins in recent years. In this study, streptokinase loaded-CS nanoparticles were prepared and the pharmacokinetic parameters of streptokinase were compared with those of naked streptokinase. The preparation method included...
Ujwala A Shinde et al.
Pharmaceutical development and technology, 19(7), 813-823 (2013-09-17)
The use of mucoadhesive biopolymers is one of the best approaches to prolong the drug residence inside the cul-de-sac, consequently increasing the bioavailability. Thus, the focus of this work was to develop mucoadhesive microspheres to overcome the limitations of ocular...
Tarek A Ahmed et al.
Life sciences, 110(1), 35-43 (2014-07-06)
First; to develop rabeprazole (RP)-alginate core coated chitosan nanoparticles (NP) utilizing water in oil (W/O) nanoemulsion technique. Second; formulation of transdermal patches loaded RP-NP that avoid drug peroral acid sensitivity and first pass effect. The influence of six factors on...
Treatment of interdigital-type tinea pedis with a 2-week regimen of wearing hygienic socks loaded with antifungal microcapsules: a randomized, double-blind, placebo-controlled study.
Chun-Wah Marcus Yuen et al.
Journal of the American Academy of Dermatology, 69(3), 495-496 (2013-08-21)
Haiping Chen et al.
Experimental cell research, 323(2), 346-351 (2014-03-19)
The structure of a tissue engineering scaffold plays an important role in modulating tissue growth. A novel gelatin-chitosan (Gel-Cs) scaffold with a unique structure produced by three-dimensional printing (3DP) technology combining with vacuum freeze-drying has been developed for tissue-engineering applications....
Augmented microfracture: is this the Holy Grail that we have been searching for in the treatment of cartilage injuries?: commentary on an article by William D. Stanish, MD, et al.: "Novel scaffold-based BST-CarGel treatment results in superior cartilage repair compared with microfracture in a randomized controlled trial".
Michael Khazzam
The Journal of bone and joint surgery. American volume, 95(18), e137-e137 (2013-09-21)
Chitosan oligosaccharides promote reverse cholesterol transport and expression of scavenger receptor BI and CYP7A1 in mice.
Zong C, Yu Y, Song G, Luo T, Li L, et al.
Exp. Biol. Med, 237(2), 194-200 (2012)
B Venkatrajah et al.
Pakistan journal of biological sciences : PJBS, 16(22), 1438-1448 (2014-02-12)
Wound healing is a long and complex process. To improve wound healing, the wound dressing cotton gauze can be functionalized by imparting moisture holding and antibacterial ability. Moisture is an important factor for wound healing and the absence of microbial...
Jing Lu et al.
Journal of chromatography. A, 1350, 61-67 (2014-05-28)
In the present paper, a new calix[4]arene derivatized chitosan bonded stationary phase (CCS4) for high performance liquid chromatography (HPLC) was synthesized and characterized. Its chromatographic performance and retention mechanism were evaluated in reversed-phase mode compared with ODS using different solute...
Bijay Singh et al.
Journal of nanoscience and nanotechnology, 14(1), 564-576 (2014-04-16)
Successful gene therapy depends on the development of efficient and cell-specific gene delivery systems. Currently, animal viral vectors have been mostly used for in vivo and in clinical trials owing to their high transduction efficiency. However, they suffer from numerous...
Héloïse Ragelle et al.
Journal of controlled release : official journal of the Controlled Release Society, 172(1), 207-218 (2013-08-24)
Recently, chitosan has attracted significant attention in the formulation of small interfering RNA (siRNA). Because of its cationic nature, chitosan can easily complex siRNA, thus readily forming nanoparticles. Moreover, chitosan is biocompatible and biodegradable, which make it a good candidate...
Piotr Mazurek et al.
Polimery w medycynie, 43(4), 297-302 (2014-03-07)
Chitin and chitosan are natural polysaccharides. In this study, we presented the possibilities of using chitin and chitosan in medical practice and experimental studies. Chitin and chitosan, based wound dressings available as commercial products, were presented. The directions of future...
Yu-Hsun Nien et al.
Journal of nanoscience and nanotechnology, 13(7), 4703-4707 (2013-08-02)
The purpose of this study was to fabricate poly(epsilon-caprolactone) (PCL)/poly ethylene oxid (PEO)/chitosan (CS) ultrafine fiber in both aligned and random structures using electrospinning technique and their process parameters were optimized. The aligned and random PCL/PEO/chitosan ultrafine fibers were also...
Tao Lou et al.
Journal of biomedical nanotechnology, 10(6), 1105-1113 (2014-04-23)
Current treatments for severe skin damage involve the grafting of extremely limited autogenic skin or the use of synthetic skin grafts that do not fully recapitulate the biological properties of native skin. In this study we developed a novel bi-layer...
Soon Kong Yong et al.
Reviews of environmental contamination and toxicology, 233, 1-43 (2014-11-05)
Chitosan originates from the seafood processing industry and is one of the most abundant of bio-waste materials. Chitosan is a by-product of the alkaline deacetylation process of chitin. Chemically, chitosan is a polysaccharide that is soluble in acidic solution and...
Bin Huang et al.
Journal of biomedical nanotechnology, 9(1), 115-123 (2013-05-01)
Synthesis of nanoparticles with desired size/morphology has enormous importance, especially in the compelling field of nanotechnology. In this case, a novel kind of raspberry-type hybrid nanoparticles was prepared by hybridization of chitosan (CS) with thioethyl pendant ligand (TPL) modified Au...
D Harikishore Kumar Reddy et al.
Advances in colloid and interface science, 201-202, 68-93 (2013-11-05)
Magnetic chitosan composites (MCCs) are a novel material that exhibits good sorption behavior toward various toxic pollutants in aqueous solution. These magnetic composites have a fast adsorption rate and high adsorption efficiency, efficient to remove various pollutants and they are...
Xiu-Ke Chen et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(4), 548-552 (2013-05-30)
To prepare chitosan-modified tripterygium glycoside nanoparticles (LMWC-TG-PLA-NPs), and assess its renal targeting property in rats. Chitosan-modified tripterygium glycoside nanoparticles (LMWC-TG-PLA-NPs) were prepared by modified spontaneous emulsification solvent evaporation method, and modified with 50% deacetylated low molecular weight chitosan (LMWC). The...
Cristian Dima et al.
Food chemistry, 195, 39-48 (2015-11-18)
The encapsulation by spray drying method of coriander essential oil (CEO) in various materials (chitosan, alginate, chitosan/alginate, chitosan/inulin) was studied. The viscoelastic properties of the oil-in-water (O/W) emulsions and the characteristics of CEO-loaded microcapsules like morphology, moisture, wettability, solubility, flowability...