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52370

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Kirsten Exall et al.
The Science of the total environment, 461-462, 371-376 (2013-06-08)
To better understand the environmental mobility of sulfonamide antibiotics and develop improved processes for their removal during wastewater treatment, stirred cell ultrafiltration (UF) experiments were conducted using both synthetic and real wastewater effluent. The interactions between selected sulfonamides (sulfaguanidine, sulfathiazole...
María Llorián-Salvador et al.
The Prostate, 75(1), 70-83 (2014-09-30)
Pain due to bone metastases of prostatic origin is a relevant clinical issue. We study here the nociceptive responses obtained in mice receiving the intratibial inoculation of RM1 prostate cancer cells. 10(2) -10(5) RM1 cells were inoculated to C57BL/6 mice...
Jade E LaDow et al.
European journal of medicinal chemistry, 46(9), 4219-4226 (2011-07-29)
A series of cationic amphiphiles, each with an aromatic core, was prepared and investigated for antimicrobial properties. The synthesized amphiphiles in this study are bicephalic (double-headed) in that they each possess two trimethylammonium head groups and a single linear alkoxy...
Denusa M Veríssimo et al.
Experimental biology and medicine (Maywood, N.J.), 240(2), 175-184 (2014-09-24)
The aim of this study was to evaluate the bone regenerative effect of glutaraldehyde (GA) cross-linking on mineralized polyanionic collagen membranes in critical-sized defects on rat calvarias. Bone calvarial defects were induced in Wistar rats, which were then divided into...
Agha Zeeshan Mirza
Journal of drug targeting, 23(1), 52-58 (2014-08-26)
The work presented here describes the fabrication of a novel drug delivery system, which consists of gold nanorods and doxorubicin, with the attachment of thioctic acid and folic acid, for the targeted release of drug to cancer cells. Doxorubicin, the...
Hailong Peng et al.
International journal of pharmaceutics, 446(1-2), 153-159 (2013-02-12)
A novel pH-responsive nano-carrier MSNs-PAA, possessing mesoporous silica nanoparticles (MSNs) cores and poly(acrylic acid) (PAA) shell-layers, was developed for controlled release of salidroside. The vinyl double bonds modified MSNs were synthesized by using cetyltrimethylammonium bromide (CTAB) as templates, tetraethyl orthosilicate...
Xing-You Gu et al.
G3 (Bethesda, Md.), 5(2), 183-193 (2014-12-07)
Seed dormancy is imposed by one or more of the embryo, endosperm, and maternal tissues that belong to two generations and represent two ploidy levels. Many quantitative trait loci (QTL) have been identified for seed dormancy as measured by gross...
Wenjun Wang et al.
Food chemistry, 141(3), 2207-2212 (2013-07-23)
In this paper, the interaction of safranine T (ST) and calix[4]arene (4,10,16,22-tetramethoxylresorcinarene carboxylic acid derivatives (TRCA)) was investigated with fluorescence spectroscopy. The results was shown that the fluorescence intensity of TRCA could be quenched by ST, and the fluorescence quenching...
Koji Takeuchi et al.
Life sciences, 110(2), 77-85 (2014-07-02)
The present study compared the effects of frequently used anti-platelet drugs, such as clopidogrel, ticlopidine, and cilostazol, on the gastric bleeding and ulcerogenic responses induced by intraluminal perfusion with 25 mM aspirin acidified with 25 mM HCl (acidified ASA) in...
Abdulrazaq Bidemi Nafiu et al.
Pharmaceutical biology, 53(5), 662-671 (2014-11-29)
Carica papaya L. (Caricaceae) fruit was shown to exhibit wound healing properties. We investigated anti-inflammatory and antioxidant potential of papaya fruit phosphate-buffered saline extract (PE) during wound healing and enhancement of the potentials due to trace ions addition. Rat excision...
Shohda A El-Maraghy et al.
Chemico-biological interactions, 229, 26-35 (2015-02-01)
The present study investigated the gastroprotective effect of crocin in ethanol-induced gastric injury in rats. Rats were allocated into a normal group, an ulcer group, a crocin-treated group, an ulcer group pretreated with crocin, and an ulcer group pretreated with...
Hadiyah N Green et al.
International journal of nanomedicine, 9, 5093-5102 (2014-11-15)
Nanoparticle (NP)-enabled near infrared (NIR) photothermal therapy has realized limited success in in vivo studies as a potential localized cancer therapy. This is primarily due to a lack of successful methods that can prevent NP uptake by the reticuloendothelial system...
Ka Yee Chan et al.
Bioorganic & medicinal chemistry letters, 21(21), 6353-6356 (2011-09-23)
Reported previously by our group, we have developed a novel class of antibacterial cationic anthraquinone analogs with superb potency (MIC <1μg/mL) against Gram positive (G+) pathogens including Methicillin-resistant Staphylococcus aureus (MRSA). However, most of these compounds only manifest modest antibacterial...
Ana L M Ivan et al.
Journal of photochemistry and photobiology. B, Biology, 138, 124-133 (2014-06-14)
Ultraviolet B (UVB) irradiation may cause oxidative stress- and inflammation-dependent skin cancer and premature aging. Pyrrolidine dithiocarbamate (PDTC) is an antioxidant and inhibits nuclear factor-κB (NF-κB) activation. In the present study, the mechanisms of PDTC were investigated in cell free...
Michael Waisberg et al.
PLoS pathogens, 10(9), e1004338-e1004338 (2014-09-12)
Invasion of mosquito salivary glands (SGs) by Plasmodium falciparum sporozoites is an essential step in the malaria life cycle. How infection modulates gene expression, and affects hematophagy remains unclear. Using Affimetrix chip microarray, we found that at least 43 genes...
Francisco J Prado-Prado et al.
Bioorganic & medicinal chemistry, 18(6), 2225-2231 (2010-02-27)
There are many of pathogen parasite species with different susceptibility profile to antiparasitic drugs. Unfortunately, almost QSAR models predict the biological activity of drugs against only one parasite species. Consequently, predicting the probability with which a drug is active against...
Siddharth Jambhrunkar et al.
Molecular pharmaceutics, 11(10), 3642-3655 (2014-08-29)
Mesoporous silica nanoparticles (MCM-41) with different surface chemistry were used as carrier system to study its influence on drug delivery and anticancer activity of curcumin (CUR). CUR was encapsulated in pristine MCM-41 (hydrophilic and negatively charged), amino functionalized MCM-41 (MCM-41-NH2...
Jihye Choi et al.
Journal of biomedical optics, 19(5), 051203-051203 (2013-12-04)
Biomarker-specific photothermal nanoparticles that can efficiently sense markers that are overexpressed in distinguished adenocarcinomas have attracted much interest in an aspect of efficacy increase of cancer treatment. We demonstrated a promising prospect of a smart photothermal therapy agent employing anti-epidermal...
Yi Min et al.
Journal of chromatography. A, 1356, 148-156 (2014-07-08)
In this work, 1.9 μm reversed-phase packing materials with superficially porous structure were prepared to achieve the rapid and high efficient separation of peptides and proteins. The silica particles were synthesized via three steps, nonporous silica particle preparation by a...
Imène Chaïr-Yousfi et al.
International immunopharmacology, 25(1), 19-29 (2015-01-21)
Lung injury and respiratory distress syndrome are frequent symptoms observed in the most severe cases of scorpion envenomation. The uncontrolled transmigration of leukocyte cells into the lung interstitium and alveolar space and pulmonary edema may be the cause of death....
Shih-Chen Hsu et al.
Small (Weinheim an der Bergstrasse, Germany), 11(2), 195-201 (2014-08-15)
Au-Cu2 O core-shell nanocubes, octahedra, and rhombic dodecahedra display facet-dependent optical properties. Furthermore, different-sized Au-Cu2 O octahedra with 58, 65, 68, and 73 nm octahedral gold cores clearly show a transition from the shell thickness-independent gold surface plasmon resonance band...
Amit Kumar Mandal et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 14(4), 788-796 (2012-11-13)
Femtosecond upconversion, single-molecule fluorescence resonance energy transfer (sm-FRET) and fluorescence correlation spectroscopy (FCS) are applied to study the competition between excited-state proton transfer (ESPT) and FRET [to rhodamine 6G (R6G)] of 8-hydroxypyranine-1,3,6-trisulfonate (HPTS) in cetyltrimethylammonium chloride (CTAC) micelles. Pyranine exhibits...
R C Beier et al.
Journal of applied microbiology, 118(2), 326-342 (2014-11-29)
To evaluate susceptibility of Pseudomonas aeruginosa veterinary isolates to antibiotics and disinfectants. Pseudomonas aeruginosa isolates collected from dogs (n = 155) and other animals (n = 20) from sixteen states during 1994-2003 were tested for susceptibility. Most isolates were resistant...
Laila Abdel-Fattah et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 136 Pt B, 178-184 (2014-10-16)
In this study, a simple and sensitive spectrophotometric method was developed for determination of Losartan potassium (LST K), an angiotensin-II receptor (type AT1) antagonist, in presence of cationic surfactant cetyltrimethylammonium bromide (CTAB). The physicochemical interaction of LST K with CTAB...
Joung Woo Han et al.
ChemSusChem, 7(2), 451-456 (2014-01-10)
Nickel catalysts are typically used for hydrogen production by reforming reactions. Reforming methane with carbon dioxide, called dry reforming of methane (DRM), is a good way to produce hydrogen or syngas (a mixture of hydrogen and carbon monoxide) from two...
Hong-Min Meng et al.
Analytical chemistry, 86(24), 12321-12326 (2014-11-18)
Glutathione (GSH) serves vital cellular biological functions, and its abnormal levels are associated with many diseases. To better understand its physiological and pathological functions, efficient methods for monitoring of GSH in living systems are desired. Although quite a few small...
Lan Ge et al.
American journal of physiology. Heart and circulatory physiology, 308(5), H500-H509 (2014-12-21)
Emerging evidence suggests a potential role of neutrophil extracellular traps (NETs) in linking sterile inflammation and thrombosis. We hypothesized that NETs would be induced during myocardial ischemia-reperfusion (I/R), and NET-mediated microthrombosis may contribute to myocardial "no-reflow". Male Wistar rats were...
Anne Fischbeck et al.
Inflammatory bowel diseases, 20(11), 1933-1941 (2014-09-05)
The heat shock protein gp96 is an endoplasmic reticulum chaperone involved in endoplasmic reticulum stress reactions. gp96 binds antigens and is secreted into extracellular space on cell stress. After reinternalization by antigen presenting cells, antigens can be transferred to major...
Jyothi C Abbar et al.
Colloids and surfaces. B, Biointerfaces, 106, 158-164 (2013-02-26)
An electrochemical method has been described for the voltammetric oxidation and determination of an antihyperlipoproteinemic drug, atorvastatin (ATOR), at a carbon paste electrode (CPE) in the presence of an enhancing agent, cetyltrimethyl ammonium bromide (CTAB) using cyclic and differential pulse...
Vitaly A Khanadeev et al.
Nanotechnology, 25(40), 405602-405602 (2014-09-13)
High-quality colloidal crystals (CCs) are important for use in photonic research and as templates for large-scale plasmonic SERS substrates. We investigated how variations in temperature, colloid concentration, and dip-drawing parameters (rate, incubation time, etc) affect the structure of 2D CCs...
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