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Ângela Sousa et al.
Journal of chromatography. A, 1366, 110-119 (2014-09-30)
Histamine and agmatine amino acid derivatives were immobilized into monolithic disks, in order to combine the specificity and selectivity of the ligand with the high mass transfer and binding capacity offered by monolithic supports, to purify potential plasmid DNA biopharmaceuticals.
Kevin B Freeman et al.
Psychopharmacology, 231(12), 2395-2403 (2014-01-09)
Recent research has demonstrated that the drug, histamine, can function as a punisher of cocaine self-administration. However, little is known about how drug punishers affect the maximum reinforcing effectiveness of drugs as reinforcers. The goal of the present study was
Isabel Sanz-Vicente et al.
Analytical and bioanalytical chemistry, 412(18), 4261-4271 (2020-05-14)
Diamino-oxidase (DAO), horseradish peroxidase (HRP), and tetramethylbenzidine (TMB) have been immobilized into cellulose to obtain circular cellulose test supports (CCTSs) for the determination of cadaverine (Cad) and putrescine (Put). During the enzymatic reaction, TMB is oxidized and a blue spot
Chikako Gemba et al.
Journal of neurophysiology, 113(10), 3720-3735 (2015-04-24)
Histamine receptors are densely expressed in the mesencephalic trigeminal nucleus (MesV) and trigeminal motor nucleus. However, little is known about the functional roles of neuronal histamine in controlling oral-motor activity. Thus, using the whole-cell recording technique in brainstem slice preparations
Nico A Jansen et al.
Journal of neurophysiology, 113(1), 58-70 (2014-10-10)
We tested the possibility that the trigeminoparabrachial tract (VcPbT), a projection thought to be importantly involved in nociception, might also contribute to sensation of itch. In anesthetized rats, 47 antidromically identified VcPbT neurons with receptive fields involving the cheek were
Anna M Piasta et al.
Analytica chimica acta, 834, 58-66 (2014-06-15)
A new procedure for determination of biogenic amines (BA): histamine, phenethylamine, tyramine and tryptamine, based on the derivatization reaction with 2-chloro-1,3-dinitro-5-(trifluoromethyl)-benzene (CNBF), is proposed. The amines derivatives with CNBF were isolated and characterized by X-ray crystallography and (1)H, (13)C, (19)F
Thomas Boehm et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 69(9), 937-950 (2020-06-04)
To measure diamine oxidase (DAO) activity with high sensitivity in complex matrices like plasma or tissue extracts radioactive putrescine or horseradish peroxidase (HRP)/hydrogen peroxide (H2O2) coupling must be used. The use of radioactive material should be avoided and HRP/H2O2 coupling
Egla Yareth Bivián-Castro et al.
Bioinorganic chemistry and applications, 603651-603651 (2009-06-27)
A mixed copper complex with deprotonated nalidixic acid (nal) and histamine (hsm) was synthesized and characterized by FTIR, UV-Vis, elemental analysis, and conductivity. The crystal structure of [Cu(hsm)(nal)H(2)O]Cl.3H(2)O (chn) showed a pentacoordinated cooper(II) in a square pyramidal geometry surrounded by
Susan McCarthy et al.
Journal of food protection, 78(7), 1343-1349 (2015-07-22)
Scombrotoxin fish poisoning (SFP), also known as histamine (Hst) poisoning, has been associated with consumption of scombroid-type fish, including tuna and tuna fish products. Preparation of commercial tuna salad contaminated with Hstproducing bacteria (HPB), combined with time-temperature abuse, can present
D Tsikas et al.
Journal of chromatography, 614(1), 37-41 (1993-04-21)
A procedure for the selective ion-pair extraction of histamine from various biological fluids and tissues by using the ion-pairing agent bis(2-ethylhexyl)hydrogen-phosphoric acid has been developed. This procedure enabled routine determination of histamine in plasma, urine and tissue samples of humans
Hong Wei et al.
Pharmacological research, 90, 58-66 (2014-10-12)
Among brain structures receiving efferent projections from the histaminergic tuberomammillary nucleus is the pontine locus coeruleus (LC) involved in descending noradrenergic control of pain. Here we studied whether histamine in the LC is involved in descending regulation of neuropathic hypersensitivity.
Yogesh Dahiya et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(40), 7934-7946 (2019-08-16)
Memory formation is crucial for the survival of animals. Here, we study the effect of different crh-1 [Caenorhabditis elegans homolog of mammalian cAMP response element binding protein 1 (CREB1)] isoforms on the ability of C. elegans to form long-term memory
Shaquria P Adderley et al.
Microcirculation (New York, N.Y. : 1994), 22(4), 237-248 (2015-01-15)
The mechanisms by which histamine increases microvascular permeability remain poorly understood. We tested the hypothesis that H1 receptor activation disrupts the endothelial barrier and investigated potential downstream signals. We used confluent EC monolayers, assessing TER as an index of barrier
Lydia M M Vermeer et al.
Experimental neurology, 263, 8-16 (2014-09-30)
Migraine is one of the most common neurological disorders, leading to more than 1% of total disability reported and over 68 million visits to emergency rooms or physician's offices each year in the United States. Three times as many women
Anna Czajkowska-Mysłek et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 105, 82-92 (2017-04-04)
Potential adverse reactions among infants and young children could appear after consumption of food containing small amounts of bioactive amines. This study presents the first assessment of biogenic amines occurrence in ready-to-eat vegetable without/with fish, meat and fruit baby products
Kristin Bjornsdottir-Butler et al.
Journal of AOAC International, 98(3), 622-627 (2015-06-19)
Histamine is the main causative agent in scombrotoxin fish poisoning, the most frequently reported illness related to fish consumption. The AOAC official method for histamine determination in fish is the fluorometric method AOAC 977.13, which is sensitive and reproducible but
Feng Xu et al.
Acta oto-laryngologica, 135(7), 698-705 (2015-04-16)
This study provides evidence that histamine induced MUC5AC mRNA expression through the activation of the core region of its promoter. It may also help in approaching new therapeutic strategies in airway mucins hypersecretory diseases. Mucin hypersecretion characterizes several respiratory diseases.
Yuki Bessho et al.
Neuroscience letters, 578, 106-110 (2014-07-06)
In mammals, it is established that histamine is a neurotransmitter and/or neuromodulator in the central nervous system. It is produced by the enzyme histidine decarboxylase (HDC) in the tuberomammillary nucleus of the posterior hypothalamus. However, HDC as well as histaminergic
Mitsuhiro Uchida et al.
Experimental animals, 64(4), 333-341 (2015-06-13)
Beagle dogs have long been employed in toxicology studies and as skin disease models. Compared with other experimental animal species, they are known to be susceptible to skin responses, such as rashes, from exposure to various chemical compounds. Here, a
Tsuyoshi Minami et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 31(7), 721-724 (2015-07-15)
This study is the first to report on the detection of biogenic amines in an aqueous solution using an organic field-effect transistor (OFET) device with an extended gate electrode modified with a layer of diamine oxidase and a horseradish peroxidase
Jesús Navarro et al.
Talanta, 208, 120392-120392 (2019-12-11)
The joint determination of putrescine (Put) and cadaverine (Cad) in the presence of other biogenic amines is studied using their enzymatic reaction with diamine oxidase (DAO). Three alternative methods are studied based on the intrinsic colorimetric properties of DAO or
J. Axelrod
Methods in Enzymology, 17B, 766-766 (1971)
Elisabeth Gludovacz et al.
eLife, 10 (2021-09-04)
Excessive plasma histamine concentrations cause symptoms in mast cell activation syndrome, mastocytosis, or anaphylaxis. Anti-histamines are often insufficiently efficacious. Human diamine oxidase (hDAO) can rapidly degrade histamine and therefore represents a promising new treatment strategy for conditions with pathological histamine
Cui Cui et al.
Bone, 72, 43-52 (2014-12-03)
Serotonin (5-HT)--a monoamine with a variety of physiological functions--has recently emerged as a major regulator of bone mass. 5-HT is synthesized in the brain and the gut, and gut-derived 5-HT contributes to circulating 5-HT levels and is a negative modulator
Shigeru Hishinuma et al.
Biochemical pharmacology, 91(2), 231-241 (2014-07-30)
Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and second-generation antihistamines for human
Richard L Watson et al.
The Journal of experimental medicine, 212(7), 1021-1041 (2015-06-24)
CD99 is a critical regulator of leukocyte transendothelial migration (TEM). How CD99 signals during this process remains unknown. We show that during TEM, endothelial cell (EC) CD99 activates protein kinase A (PKA) via a signaling complex formed with the lysine-rich
S D Keir et al.
Pulmonary pharmacology & therapeutics, 33, 25-31 (2015-05-27)
Airways obstruction induced by intravenously administered bradykinin is abolished in guinea pigs treated with indomethacin, which has been shown to be, at least in part thromboxane dependent. As thromboxane is primarily generated from circulating platelets, we investigated whether airways obstruction
Markus Waldeck-Weiermair et al.
Sensors (Basel, Switzerland), 15(6), 13052-13068 (2015-06-09)
Cameleons are sophisticated genetically encoded fluorescent probes that allow quantifying cellular Ca2+ signals. The probes are based on Förster resonance energy transfer (FRET) between terminally located fluorescent proteins (FPs), which move together upon binding of Ca2+ to the central calmodulin
Carlos Daniel Zappia et al.
Scientific reports, 5, 17476-17476 (2015-12-05)
Histamine H1 receptor (H1R) antagonists and glucocorticoid receptor (GR) agonists are used to treat inflammatory conditions such as allergic rhinitis, atopic dermatitis and asthma. Consistent with the high morbidity levels of such inflammatory conditions, these receptors are the targets of
Parul S Pall et al.
The journal of pain : official journal of the American Pain Society, 16(8), 741-749 (2015-05-24)
Allergic contact dermatitis (ACD) is a common condition that can significantly affect the quality of life. Contact with allergens results in delayed hypersensitivity reactions involving T lymphocytes, with associated skin inflammation and spontaneous itch and nociceptive sensations. However, psychophysical studies of these
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