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Showing 1-30 of 70 results for "56-89-3" within Papers
J Sadeghinezhad et al.
Anatomia, histologia, embryologia, 42(3), 201-212 (2012-09-05)
Most investigations related to the characterisation of the enteric nervous system (ENS) are pivoted on the intestine of small rodents, but few studies are available on the ENS of wild or 'unconventional' rodents. Anti-PGP 9.5 and anti-Hu antibodies were utilised
M Pirmohamed et al.
Pharmacogenetics, 10(8), 705-713 (2001-02-24)
The use of co-trimoxazole in HIV-positive patients has been associated with a high frequency (40-80%) of hypersensitivity reactions. This has been attributed to the bioactivation of the sulphonamide component, sulphamethoxazole (SMX), to its toxic hydroxylamine and nitroso metabolites. The aim
Guilherme A F Rollin et al.
Clinical endocrinology, 82(6), 793-800 (2014-11-08)
To analyse the performance of the desmopressin (DDAVP) test in the diagnosis of Cushing's disease (CD). This was a prospective cohort study of 124 patients with suspected hypercortisolism who were recruited from an outpatient endocrinology clinic and investigated for Cushing's
A A Palmer et al.
Pathology, 17(2), 335-339 (1985-04-01)
Four methods were compared for identifying amelanotic and oligomelanotic melanomas in paraffin sections of formalin-fixed metastases from subjects with primary cutaneous melanomas. Of the amelanotic and oligomelanotic metastases a characteristic pattern of fluorescence was seen with an incident-light fluorescence microscope
C Montague et al.
American journal of clinical pathology, 104(4), 472-476 (1995-10-01)
Two thirds of patients hospitalized to rule out acute myocardial infarction (AMI) are eventually found to have a non-AMI diagnosis, whereas 2% to 8% of patients with AMI are inappropriately discharged from the emergency department. Myoglobin has been shown to
Virginie Lattard et al.
Drug metabolism and disposition: the biological fate of chemicals, 30(2), 119-128 (2002-01-17)
The expression of flavin-containing monooxygenases (FMOs) in dog liver microsomes was suggested by a high methimazole S-oxidase activity. When the reaction was catalyzed by dog liver microsomes, apparent V(max) and K(m) values were 6.3 nmol/min/mg and 14 microM, respectively. This
Patrick Jacquemin et al.
Gene expression patterns : GEP, 3(5), 639-644 (2003-09-16)
Onecut (OC) transcription factors are evolutionarily conserved proteins with important developmental functions. They contain a bipartite DNA-binding domain composed of a single cut domain associated with a divergent homeodomain. The human genome contains three Onecut paralogues, Hnf6 (also called Oc1)
Nafis Shafizadeh et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 21(8), 1011-1018 (2008-06-10)
Glypican-3 is a heparin sulfate proteoglycan normally expressed in fetal liver and placenta, but not in normal adult liver. Preliminary studies have shown that glypican-3 can be useful for the diagnosis of hepatocellular carcinoma. We performed immunohistochemistry for glypican-3 on
S M Thompson et al.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 25(1), 108-111 (2016-08-06)
Injury to the proximal hamstring complex (PHC) is becoming more frequently diagnosed. Patients attending our tertiary referral centre demonstrated 'pathological changes' in the unaffected normal contralateral PHC on MRI. The prevalence of PHC pathology, however, has not been previously documented
Tayfun Güngör et al.
Lancet (London, England), 383(9915), 436-448 (2013-10-29)
In chronic granulomatous disease allogeneic haemopoietic stem-cell transplantation (HSCT) in adolescents and young adults and patients with high-risk disease is complicated by graft-failure, graft-versus-host disease (GVHD), and transplant-related mortality. We examined the effect of a reduced-intensity conditioning regimen designed to
S Djezzar et al.
International journal of legal medicine, 123(3), 213-219 (2008-10-18)
Psychoactive substances may be administered without the knowledge of a victim in order to induce incapacitation and thus facilitate criminal actions. The characteristics of the victims and the drugs used in such suspected chemical submissions (CS) were analyzed in 309
Kyoichi Kaira et al.
AJR. American journal of roentgenology, 195(5), 1204-1211 (2010-10-23)
PET with a novel tracer, L-[3-¹⁸F]-α-methyl tyrosine (¹⁸F-FMT), has been studied in lung cancer. We evaluated ¹⁸F-FMT PET for therapy response in comparison with ¹⁸F-FDG PET. Eighteen patients with lung cancer underwent PET studies with ¹⁸F-FMT and FDG before and
Narayan Prasad et al.
Lupus, 29(8), 845-853 (2020-05-22)
Lupus nephritis (LN) has a considerable impact on the morbidity and mortality of systemic lupus erythematosus (SLE) patients. Long-term comparative outcome data from the Indian subcontinent on treatment regimens with cyclophosphamide (CYP) and mycophenolate mofetil (MMF) are sparse. We assessed
Pieter Sonneveld et al.
Blood, 125(3), 449-456 (2014-11-16)
This multicenter phase 2 study of the European Myeloma Network investigated the combination of carfilzomib, thalidomide, and dexamethasone (KTd) as induction/consolidation therapy for transplant-eligible patients with previously untreated multiple myeloma (N = 91). During KTd induction therapy, patients received 4
Stephen Z Levine et al.
Schizophrenia research, 145(1-3), 125-127 (2013-02-12)
The treatment and measurement of negative symptoms are currently at issue in schizophrenia, but the clinical meaning of symptom severity and change is unclear. To offer a clinically meaningful interpretation of severity and change scores on the Scale for the
H J Jun et al.
British journal of cancer, 99(1), 167-172 (2008-07-03)
The excision repair cross-complementation group 1 (ERCC1) enzyme plays a rate-limiting role in the nucleotide excision repair pathway and is associated with resistance to platinum-based chemotherapy. The purpose of this study was to evaluate the role of ERCC1 expression as
P Sabbatini et al.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 17(3), 589-594 (2007-02-16)
The objective of this study was to analyze retrospective populations with recurrent ovarian cancer to assess differences in CA-125 patterns during chemotherapy. The populations included all patients treated between January 1994 and January 2004, who received liposomal doxorubicin and topotecan
Andrew Fong et al.
American journal of clinical pathology, 120(1), 93-100 (2003-07-18)
We immunohistochemically evaluated 94 cases of urothelial carcinoma (UC) of the urinary bladder for the expression of caveolin (Cav)-1 and Cav-2. Neither benign urothelium present in 22 cases nor flat carcinoma in situ present in 10 cases stained for Cav-1
Michael H Gold et al.
Journal of drugs in dermatology : JDD, 11(4), 514-518 (2012-03-29)
Topical antifungal treatment is a mainstay of therapy for Seborrehic Dermatitis (SD). Although the amidazole and ciclopyridine antifungals have been extensively studied, few clinical efficacy data are available for topical allylamine therapy in SD. The objective of this open-label exploratory
N Bhala et al.
Lancet (London, England), 382(9894), 769-779 (2013-06-04)
The vascular and gastrointestinal effects of non-steroidal anti-inflammatory drugs (NSAIDs), including selective COX-2 inhibitors (coxibs) and traditional non-steroidal anti-inflammatory drugs (tNSAIDs), are not well characterised, particularly in patients at increased risk of vascular disease. We aimed to provide such information
G Janoray et al.
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 18(3), 191-197 (2014-05-20)
Robotic stereotactic body radiation therapy is a new option to treated unresecable liver tumours. The objectives were to assess the tolerance of this technique, to identify predictive factors for toxicity and evaluate the efficiency of this treatment. From June 2010
Gerald Holtmann et al.
Gastroenterology, 126(4), 971-979 (2004-04-02)
In patients with functional dyspepsia, altered alpha-adrenoreceptor function and depression are prevalent, features that are linked to a G-protein beta 3 (GNB3) subunit gene polymorphism (C825T). We aimed to assess the association of specific G-protein beta 3 subunit genotypes with
M Llansola et al.
Neuroscience, 133(1), 185-191 (2005-05-17)
Hyperammonemia impairs signal transduction associated to glutamate receptors and phosphorylation of some neuronal proteins including microtubule-associated protein 2 (MAP-2). The aim of this work was to analyze the effects of hyperammonemia on modulation of MAP-2 phosphorylation by metabotropic glutamate receptors
Aron D Mosnaim et al.
Neurochemical research, 38(4), 842-846 (2013-02-08)
Phenylethylamine and its monomethylated derivatives p-methylphenylethylamine, α-methylphenylethylamine, phenylethylamine itself, N-methylphenylethylamine, o-methylphenylethylamine, and β-methylphenylethylamine, readily cross the blood-brain barrier showing a brain-uptake index (%) ± SD (water considered 100 %), of 108 ± 11, 98 ± 14, 83 ± 6, 78
Gregor Theilmeier et al.
Blood, 99(12), 4486-4493 (2002-05-31)
Platelets are thought to play a causal role during atherogenesis. Platelet-endothelial interactions in vivo and their molecular mechanisms under shear are, however, incompletely characterized. Here, an in vivo platelet homing assay was used in hypercholesterolemic rabbits to track platelet adhesion
Barbara Wusk et al.
European journal of clinical pharmacology, 60(1), 5-10 (2004-02-27)
More than 11% of the Caucasian population are heterozygous or homozygous carriers of thiopurine S-methyltransferase (TPMT) mutants and are at risk for toxic side effects when treated with thiopurine drugs. Therefore, screening for TPMT polymorphisms in a patient prior to
Outi Lindström et al.
Pancreas, 38(8), e215-e220 (2009-09-30)
To study in patients with acute pancreatitis (AP) the plasma soluble form of the receptor for advanced glycation end products (sRAGE) and high-mobility group box chromosomal protein 1 (HMGB1) levels, followed-up for 12 days after hospitalization, in relation to the
Julia Kirchheiner et al.
British journal of clinical pharmacology, 55(1), 51-61 (2003-01-22)
The cytochrome P450 enzyme CYP2C9 catalyses the 4'-hydroxylation of the nonsteroidal analgesic drug diclofenac in humans. We studied the influences of the known amino acid variants, CYP2C9*2 (Arg144Cys) and CYP2C9*3 (Ile359Leu), on diclofenac pharmacokinetics after a 50-mg oral dose of
Moniek G P J Cox et al.
Circulation. Arrhythmia and electrophysiology, 3(2), 126-133 (2010-03-11)
Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) Diagnostic Task Force Criteria (TFC) proposed in 1994 are highly specific but lack sensitivity. A new international task force modified criteria to improve diagnostic yield. A comparison of diagnosis by 1994 TFC versus newly proposed
Noortje Thielen et al.
Annals of hematology, 92(8), 1049-1056 (2013-04-11)
Despite the revolutionary change in the prognosis of chronic myeloid leukemia (CML) patients with the introduction of imatinib, patients with resistant disease still pose a considerable problem. In this multicenter, randomized phase III trial, we investigate whether the combination of
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