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Glycosyltransferases: Tools for Synthesis and Modification of Glycans
The presence of multiple functional groups and stereocenters in complex carbohydrates makes them challenging targets for the organic chemist.
β-(1—>4)-Galactosyltransferase Kit
β(1→4) Galactosyltransferase from bovine milk (GalT, EC is one of the most extensively studied mammalian glycosyltransferases with regard to synthesis and substrate specificity.
Glycosyltransferases were initially considered to be specific for a single glycosyl donor and acceptor, which led to the one enzyme-one linkage concept. Subsequent observations have refuted the theory of absolute enzymatic specificity by describing the transfer of analogs of some...
Mole Day 2021 Contest Official Rules
Mole Day is October 23 (1023), in honor of Avogadro's Number. Solve the chemistry problem below and win an awesome pair of Mole Day socks while supplies last. Coming soon! Save up to 40% on select chemistry products October 18...
Trost Ligands
The Trost group at Stanford University has pioneered the use of C-2 symmetric diaminocyclohexyl (DACH) ligands in AAA, allowing for the rapid synthesis of a diverse range of chiral products with a limited number of chemical transformations.
Sigma Receptors
Sigma receptors may constitute favorable targets for drug design in conditions such as psychiatric and movement disorders, amnesia, depression, cancer, inflammation and cocaine addiction.
Organosilanes for Cross-coupling
Over the past several years, Pd-catalyzed cross-coupling of silicon compounds has rapidly gained acceptance as a suitable alternative to more commonly known methods such as: Stille (Sn), Kumada (Mg), Suzuki (B), and Negishi (Zn) cross-couplings.
Overcoming Aggregation in Solid-phase Peptide Synthesis
Learn how to overcome aggregation in Solid Phase Peptide Synthesis
Acetylcholine Synthesis and Metabolism
Acetylcholine is synthesized from acetyl coenzyme A and choline by the enzyme choline acetyltransferase. In addition to its synthesis in the liver, choline employed in acetylcholine production is derived from dietary sources.
Setting up the MilliSentials Lab Labeling System
The MilliSentials™ Lab Labeling System has been designed as a complete solution for laboratory labeling. As part of that solution we’ve put together a how-to-setup video, troubleshooting section, and list of materials to support the system.
Listeria: a Survivor
In recent years it has been recognized that Listeria is an important public health problem. The disease affects primarily people of advanced age, pregnant women, newborns, and adults with weakened immune systems.
Nanomaterials for Advanced Applications
The union of distinct scientific disciplines is revealing the leading edge of Nanotechnology.
Serotonin Receptors
We offer many products related to serotonin receptors for your research needs.
Glycan Labeling
Structural modifications of proteins are essential to living cells. When aberrantly regulated they are often the basis of disease. Glycans are responsible for much of the structural variation in biologic systems, and their representation on cell surfaces is commonly called...
Ficoll 400 is a highly branched polymer formed by the copolymerization of sucrose and epichlorohydrin. Ficoll 400 is completely non-ionic. Because of the abundance of hydroxyl groups, Ficoll 400 is very hydrophilic and extremely water-soluble.
Phospholipase A2
Phospholipase A2 (PLA2) designates a class of enzymes that hydrolyze the sn-2 ester of glycerophospholipids to produce a fatty acid and a lysophospholipid. It has become clear that some of these enzymes liberate arachidonic acid in mammalian cells for the...
Canonical Wnt / β-Catenin Signaling
We review the Wnt signaling pathway (also, canonical Wnt or beta (β)-catenin pathway) and provide links to related products at
Dextran and Related Polysaccharides
Learn about C6H10O6 or dextran formation, classes and naming from MilliporeSigma. Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, which have a linear backbone of α-linked d-glucopyranosyl repeating units.
Asymmetric Allylic Alkylation
Palladium-catalyzed asymmetric allylic alkylation (AAA) has proven to be an exceptionally powerful method for the efficient construction of stereogenic centers.
Conducting Polymer Device Applications
The application of conducting polymers at the interface with biology is an exciting new trend in organic electronics research.
Phosphoinositide Kinases
Sigma-Aldrich offers many products related to phosphoinositide kinases for your research needs.
Probiotics and Human Health
Today, diverse studies report the benefits of probiotics, such as inhibitory effects on pathogens, aid in the management or prevention of chronic intestinal inflammatory diseases or atopic syndromes, and support to the immune system. Potential beneficial applications abound, researchers continue...
Graphene-Based Composites and their Unique Renewable Energy Applications
Graphene is a unique two-dimensional (2D) structure of monolayer carbon atoms packed into a dense honeycomb crystal that has attracted great interest due to its diverse and fascinating properties.
Our offers many products related to PKA & PKG for your research needs.
Lightweight Metal Matrix Nanocomposites - Stretching the Boundaries of Metals
Composite materials that traditionally incorporate micron scale reinforcements in a bulk matrix offer opportunities to tailor material properties such as hardness, tensile strength, ductility, density, thermal and electrical conductivity, and wear resistance.
Micro- and Nanofabricated Biomaterials for the Study of Cells and Microtissues
Biomaterials science involves the design and fabrication of smart materials for studying, directing, or mimicking biology. For successful integration of biomaterials in biological research, a meaningful understanding of biological systems is required.
Supelco ASSET™EZ4 Dry Samplers for Isocyanates
Easy-to-use air sampler offering ultimate sensitivity for collection and measurement of vapor phase and particulate isocyanate monomers and oligomers.
Gold Nanorod Synthesis
Plasmonic nanoparticles have unique optical properties that can be tailored to suit a variety of applications in the biotechnology1–8 and electronics9–16 industries.
Delivery of Nucleic Acids Using Polymers
Delivery of Nucleic Acids Using Polymers