Showing 1-30 of 139 results for "59-23-4"
U Ribič et al.
Journal of applied microbiology, 122(5), 1186-1196 (2017-02-24)
The purpose of this study was the genotypic and phenotypic characterization of 57 strains of Staphylococcus epidermidis isolated from cleanroom environments, based on their biofilm formation and antimicrobial resistance profiles. Biofilm formation was investigated using real-time PCR (icaA, aap, bhp...
L Z Rassenti et al.
The Journal of experimental medicine, 185(8), 1435-1445 (1997-04-21)
We determined the immunoglobulin (Ig) V(H) subgroup expressed by the leukemia cells of 108 patients with B cell chronic lymphocytic leukemia (CLL). Surprisingly, we found that six samples (5%) each expressed Ig of more than one V(H) subgroup. Southern blot...
Serena S Freeman et al.
Cancer, 113(6), 1453-1461 (2008-08-16)
Osteosarcoma cell lines and tumors have been shown to express epidermal growth factor receptor (EGFR) and harbor amplifications at the EGFR locus. In this study, the authors further analyzed the genomic features of EGFR in osteosarcoma tumors and investigated whether...
Sankar D Navaneethan et al.
Clinical nephrology, 82(1), 16-25 (2014-06-03)
Higher serum phosphorus is associated with an increased mortality among those with chronic kidney disease (CKD). We examined the practice patterns of phosphate binder use to lower serum phosphorus levels and their associations with mortality in the non-dialysisdependent CKD population....
Curtis L Hedberg et al.
The Pediatric infectious disease journal, 23(5), 424-428 (2004-05-08)
Sepsis commonly complicates the clinical course of critically ill very low birth weight infants, with as many as 30% developing hospital-acquired bacteremia. The tumor necrosis factor alpha (TNF-alpha) -- 308 G/A single nucleotide polymorphism (SNP) is associated with adverse outcome...
Nobuko Mori et al.
Journal of radiation research, 44(3), 249-254 (2003-12-03)
BALB/c mice are susceptible to radiation-induced mammary tumors as well as lymphomas. We investigated the effects of the p53 deficient allele and of X-irradiation on the tumor spectrum in the BALB/c background. Substantially all p53 -/-animals died of thymic lymphomas...
B Liegl et al.
Histopathology, 50(4), 439-447 (2007-04-24)
Mammary Paget's disease (MPD) and extramammary Paget's disease (EMPD) are rare neoplasms. The aim of this study was, by the use of immunohistochemistry, to derive further information about the cell(s) of origin, find a diagnostically useful immunohistochemical panel and investigate...
Suzanne D DeBrosse et al.
Molecular genetics and metabolism, 107(3), 394-402 (2012-10-02)
Pyruvate dehydrogenase complex (PDC) deficiency is a relatively common mitochondrial disorder that primarily presents with neurological manifestations and lactic acidemia. We analyzed the clinical outcomes and neurological features of 59 consented symptomatic subjects (27 M, 32 F), who were confirmed...
E Richter et al.
Toxicology, 144(1-3), 83-91 (2000-04-27)
The pharmacokinetics of in vitro metabolism of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK; concentration range 0.03-250 microM) and its proximal metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL; 0.04-250 microM), were determined in Syrian golden hamster liver, lung, and kidney tissue slices in organ culture under...
Takashi Shibutani et al.
International journal of clinical oncology, 25(3), 502-507 (2019-11-05)
The purpose of this study was to determine the optimal regimen of neoadjuvant chemotherapy (NAC) for advanced epithelial ovarian, fallopian tube, and peritoneal cancers. A clinical information survey involving 171 patients with advanced epithelial ovarian, fallopian tube, or primary peritoneal...
Li-ya Yuan et al.
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 39(2), 202-206 (2010-04-14)
To investigate the incidence of JAK2V617F gene point mutation in patients with myeloproliferatives diseases (MPD) and its clinical significance. Genomic DNA from bone marrow and peripheral blood cells were extracted from 68 patients with MPD. Allele specific polymerase chain reaction...
F Chiadmi et al.
Journal of clinical pharmacy and therapeutics, 30(3), 255-258 (2005-05-18)
To assess the stability of doxorubicin combined with Radioselectan. Solutions of doxorubicin 5 mg/mL were prepared from commercially available 50 mg powder with 10 mL of Radioselectan. They were stored in glass syringes at 4, 25 and 45 degrees C....
Irene A Barbazetto et al.
Investigative ophthalmology & visual science, 49(9), 3806-3811 (2008-05-27)
To investigate the prevalence of sequence variants in the ATM gene and to determine the frequency of major age-related macular degeneration (AMD)-associated variants in CFH, CFB, and 10q26 loci in patients with idiopathic perifoveal telangiectasia (IPT). Thirty patients with diagnoses...
Guy Bouvier et al.
Photochemistry and photobiology, 91(6), 1479-1487 (2015-09-04)
Brimonidine at 0.18%, 1% and 2% concentrations applied topically in hairless mice significantly decreased tumor burden and incidences of erythema, flaking, wrinkling and skin thickening induced by UVR. The unbiased median week to tumor ≥1 mm was increased by the...
Sofia Mayans et al.
BMC medical genetics, 8, 3-3 (2007-02-07)
Polymorphisms in and around the CTLA-4 gene have previously been associated to T1D and AITD in several populations. One such single nucleotide polymorphism (SNP), CT60, has been reported to affect the expression level ratio of the soluble (sCTLA-4) to full...
Jiqing Ye et al.
Human pathology, 45(12), 2430-2436 (2014-10-15)
AT-rich interactive domain-containing protein 1A (ARID1A), a chromatin remodeling gene recently discovered to be a tumor suppressor in ovarian cancers, has been found to be mutated at low frequencies in many other tumors including colorectal carcinoma (CRC). An association between...
Rui Chai et al.
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 14(8), 627-630 (2011-08-26)
To explore the correlation between multi-drug resistance-associated protein 4(MRP4) and the sensitivity of rectal cancer to radiation. A total of 95 patients with advanced rectal cancer and received radiation therapy between January 2000 and January 2009. MRP4 and P53 protein...
B Gammelgaard et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 13(1-2), 82-88 (1999-08-13)
The purpose of these studies was to compare the in vitro absorption of two inorganic chromium(III) compounds: chromium chloride and chromium nitrate, with organic chromium(III)-picolinate; and to investigate if any in vitro metabolism of chromium(VI) takes place. The in vitro...
Hakan Ozornek et al.
American journal of reproductive immunology (New York, N.Y. : 1989), 64(2), 87-92 (2010-02-24)
To compare the prevalence of 112T>C point mutations among women experiencing RPL with fertile control women. Buccal swabs were obtained from 232 individuals: 136 with a history of >or=2 abortions, 37 with at least 2 live births and 59 with...
Jennifer A Bennett et al.
The American journal of surgical pathology, 44(11), 1441-1449 (2020-06-23)
Inflammatory myofibroblastic tumors (IMT) of the uterus may be underrecognized as their morphology and immunophenotype may overlap with myxoid variants of uterine smooth muscle tumors and endometrial stromal tumors. Although ALK is a helpful biomarker, not all uterine IMTs are...
Sonia Palminiello et al.
Brain research, 1268, 162-173 (2009-03-11)
Our previous proteomic studies disclosed upregulation of alphaB-crystallin, a small heat shock protein, in the brain tissue of Ts65Dn mice, a mouse model for Down syndrome (DS). To validate data obtained in model animals, we studied at present the levels...
Neta Pessah et al.
Journal of medicinal chemistry, 52(8), 2233-2242 (2009-03-20)
2,2,3,3-Tetramethylcyclopropanecarboxylic acid (TMCA, 4) is a cyclic analogue of the antiepileptic drug (AED) valproic acid (VPA) (1). alpha-F, alpha-Cl, alpha-Br, and alpha-methyl derivatives of 4 and their amides were synthesized and tested in rodent models for anticonvulsant potency and AED-induced...
Ines Nevelsteen et al.
Journal of vascular research, 50(6), 486-497 (2013-11-07)
Insulin resistance, dyslipidemia and hypertension are independent mediators of endothelial dysfunction. It is incompletely defined whether dyslipidemia and hypertension in addition to diabetes mellitus type II (DMII), as seen in the metabolic syndrome (MS), worsen diabetes-induced endothelial dysfunction. Furthermore, it...
P Sabbatini et al.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 17(3), 589-594 (2007-02-16)
The objective of this study was to analyze retrospective populations with recurrent ovarian cancer to assess differences in CA-125 patterns during chemotherapy. The populations included all patients treated between January 1994 and January 2004, who received liposomal doxorubicin and topotecan...
Po-Ren Hsueh et al.
Antimicrobial agents and chemotherapy, 49(2), 512-517 (2005-01-28)
The susceptibilities of nonduplicate isolates to six antifungal agents were determined for 391 blood isolates of seven Candida species, 70 clinical isolates (from blood or cerebrospinal fluid) of Cryptococcus neoformans, and 96 clinical isolates of four Aspergillus species, which were...
R R Gainetdinov et al.
Journal of neurochemistry, 70(5), 1973-1978 (1998-05-08)
The neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) has been proposed to be attenuated by sequestration into intracellular vesicles by the vesicular monoamine transporter (VMAT2). The purpose of this study was to determine if mice with genetically reduced levels of VMAT2 (heterozygote...
Eudora Eng et al.
Microvascular research, 65(3), 137-144 (2003-04-25)
We tested the hypothesis that in endothelial cells, chronic arterial shear stress represses both the transactivator nuclear factor-kappaB (NF-kappaB) and subsequent platelet-derived growth factor (PDGF)-B gene transcription. Bovine aortic endothelial (BAE) and glomerular capillary endothelial (GEN) cells were subjected to...
Liana Adam et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(2), 641-651 (2018-10-26)
Little is known about the genetic alterations characteristic of small bowel adenocarcinoma (SBA). Our purpose was to identify targetable alterations and develop experimental models of this disease.Experimental Design: Whole-exome sequencing (WES) was completed on 17 SBA patient samples and targeted-exome...
D Bellet et al.
The Journal of clinical endocrinology and metabolism, 82(9), 3169-3172 (1997-09-01)
Recently, a new member of the insulin gene superfamily termed insulin-like 4 (INSL4) was identified in the human placenta and uterus. The present study investigated whether placenta translates INSL4 mRNA into a putative peptide named early placenta insulin-like (EPIL). Among...
Anil Sapru et al.
Anesthesiology, 110(5), 1086-1091 (2009-04-24)
Higher plasma and pulmonary edema fluid levels of plasminogen activator inhibitor-1 (PAI-1) are associated with increased mortality in patients with pneumonia and acute lung injury. The 4G allele of the 4G/5G polymorphism of the PAI-1 gene is associated with higher...

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.