María Teresa Sánchez-Fito et al.
Biopreservation and biobanking, 13(4), 287-295 (2015-08-19)
It has been known for decades that many cytokines, such as IL-2, IL-6, and IL-12, bind to heparin. Even though some enzyme-linked immunosorbent assays (ELISA) use antibody-recognizing epitopes not affected by this binding, ELISA manufacturers often warn that heparinized plasma