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Dong-Woon Kim et al.
Circulation, 109(12), 1558-1563 (2004-03-10)
Paclitaxel has been shown to inhibit vascular smooth muscle cell migration and proliferation contributing to neointimal formation. This study tested whether novel oral formulations of paclitaxel can prevent neointimal formation in a rat carotid artery injury model. Oral formulations of
Franco Cataldo
Chemistry and physics of lipids, 163(6), 524-529 (2010-03-27)
Unsaturated lipids when exposed to air at room temperature undergo a slow autoxidation. When fullerene C(60) was dissolved in selected lipids (ethyl oleate, ethyl linoleate, linseed oil and castor oil) the spectrophotometric analysis shows that the oxidation is concentrated to
Aya Ouchi et al.
Lipids, 44(10), 935-943 (2009-09-19)
A kinetic study of the prooxidant effect of alpha-tocopherol was performed. The rates of allylic hydrogen abstraction from various unsaturated fatty acid esters (ethyl stearate 1, ethyl oleate 2, ethyl linoleate 3, ethyl linolenate 4, and ethyl arachidonate 5) by
T Miyake et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 34(10), 1009-1011 (1996-10-01)
Ethyl linoleate, ethyl linolenate, ethyl arachidonate and cod liver oil were oxidized with Fenton's reagent. Acrolein, malonaldehyde and 4-hydroxynonenal formed were derivatized to N-methylpyrazoline, N-methylpyrazole and 5-(1'-hydroxyhexyl)-1-methyl-2-pyrazoline with N-methylhydrazine, respectively. The derivatives were simultaneously analysed by gas chromatograph equipped with
Toshiya Masuda et al.
Journal of agricultural and food chemistry, 54(16), 6069-6074 (2006-08-03)
In our studies of the chain-breaking antioxidant mechanism of natural phenols in food components, ferulic acid, a phenolic acid widely distributed in edible plants, especially grain, was investigated. The radical oxidation reaction of a large amount of ethyl linoleate in
H Hara et al.
The Journal of nutrition, 126(4), 800-806 (1996-04-01)
Oxidized ethyl linoleate (OEL) was prepared by aeration at low temperature. Peroxide value (POV, mEq/kg lipid) of OEL was 1400; the major oxidized compounds were 9-hydroperoxy-cis, trans- and 13-hydroperoxy-trans, cis-octadecadienoate. Rats fed fiber-free or sugar-beet fiber (SBF, 100g/kg diet) diets
A Murakami et al.
Oncology, 53(5), 386-391 (1996-09-01)
The anti-tumor-promoting activity of 1'-acetoxychavicol acetate (ACA) was examined in a two-stage carcinogenesis experiment in ICR mouse skin using 7,12-dimethylbenz[a]anthracene (0.19 mumol) and 12-O-tetradecanoylphorbol-13-acetate (TPA; 1.6 nmol). Topical application of ACA (160 nmol) markedly reduced the average number of tumors
D L Luthria et al.
Biochimica et biophysica acta, 1213(1), 1-4 (1994-06-23)
In order to determine how dietary linoleate is metabolized, rats were maintained on a chemically defined diet containing 1.6% ethyl linoleate. After 5 weeks the linoleate was replaced by an equal amount of ethyl 9,10,12,13-d4-linoleate. The animals were killed 3
Jun Liu et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 31(3), 340-342 (2008-07-16)
Volatile oil from the seed of Aquilaria sinensis was extracted with Petroleum ether. Anti-bacterial bioassay of the oil against methicillin-resistant Staphylococcus aureus (MRSA) was carried out by paper disco diffusion method. The result showed that the oil possessed inhibitory activity
K Schweikert et al.
International journal of cosmetic science, 32(1), 29-34 (2009-10-13)
UV light induces multiple damages including protein oxidation on skin. Oxidized proteins if not degraded by the proteasome would eventually accumulate causing metabolic damage, elastosis and pigment formation such as lipofuscin. During ageing, the activity of the proteasome decreases dramatically
Q Chen et al.
Lipids, 35(8), 871-879 (2000-09-13)
Several experimental approaches were used to determine whether rat liver and testes express an acyl-CoA-dependent delta8 desaturase. When [1-14C]5,11,14-eicosatrienoic acid was injected via the tail vein, or directly into testes, it was incorporated into liver and testes phospholipids, but it
Linoleic and linolenic acids and acne vulgaris.
A C Logan
The British journal of dermatology, 158(1), 201-202 (2007-11-22)
"Fast autoxidation of ethyl linoleate catalyzed by [Mn (acac) 3] and bipyridine: A possible drying catalyst for alkyd paints"
Gorkum VR, et al.
Inorganic Chemistry, 43(08), 2456-2458 (2004)
R H Stadler et al.
Biological trace element research, 47(1-3), 299-305 (1995-01-01)
The anti- and pro-oxidative effects of phenolic compounds and antioxidants were studied in two different in vitro model systems utilizing ethyl linoleate and 2'-deoxyguanosine (2'-dG) as oxidative substrates, and a Fenton reaction (H2O2, Fe2+) to initiate oxidation. Oxidation of the
T Nishiyama et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 32(11), 1047-1051 (1994-11-01)
The inhibitory effect of 2"-O-glycosyl isovitexin (2"-O-GIV), isolated from young barley leaves, on glyoxal formation from the oxidative degradation of three fatty acid ethyl esters was measured. Ethyl linoleate, ethyl linolenate and ethyl arachidonate were oxidized by Fenton's reagent. Glyoxal
Yun Ding et al.
Current biology : CB, 29(7), 1089-1099 (2019-03-19)
It is unclear where in the nervous system evolutionary changes tend to occur. To localize the source of neural evolution that has generated divergent behaviors, we developed a new approach to label and functionally manipulate homologous neurons across Drosophila species.
M Laposata et al.
Alcoholism, clinical and experimental research, 24(10), 1488-1491 (2000-10-25)
Fatty acid ethyl esters (FAEE) are nonoxidative ethanol metabolites that have been shown to be long term markers of ethanol intake and have been implicated as mediators of ethanol-induced cell injury. Previous studies have indicated that the fatty acid composition
A J Ham et al.
Chemical research in toxicology, 13(12), 1243-1250 (2000-12-22)
In these studies, we demonstrate that N(2),3-ethenoguanine (N(2), 3-epsilonGua) is formed from lipid peroxidation as well as other oxidative reactions. Ethyl linoleate (EtLA) or 4-hydroxy-2-nonenal (HNE) was reacted with dGuo in the presence of tert-butyl hydroperoxide (t-BuOOH) for 72 h
"4-Hydroxy-2-nonenal and ethyl linoleate form N 2, 3-ethenoguanine under peroxidizing conditions"
Ham.L J-A, et al.
Chemical Research in Toxicology, 1243-1250 (2000)
J Klein et al.
Therapeutic drug monitoring, 21(6), 644-646 (1999-12-22)
The authors report testing the meconium of a newborn for the presence of FAEE. Meconium from a newborn of a woman who acknowledged drinking beer throughout pregnancy was tested. The authors also tested the meconiums of 3 newborns whose mothers
Bokai Lei et al.
Molecular pharmaceutics, 7(3), 844-853 (2010-03-31)
The development of HIV protease inhibitors (PIs) has been one of the most significant advances of the past decade in controlling HIV infection. Unfortunately, the benefits of HIV PIs are compromised by serious side effects. One of the most frequent
Jennifer Peterson et al.
The Journal of pediatrics, 152(6), 788-792 (2008-05-22)
To determine the relationship between fatty acid ethyl esters (FAEE) in meconium and neurodevelopment in infants exposed to alcohol in utero at 6.5 months, 1 year, and 2 years of age. A secondary analysis of a prospective cohort of mothers
Lin Lu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(5), 597-600 (2012-06-15)
To establish a new rapid method to screen potential hepatoprotective compounds from traditional Chinese medicine, and identify the hepatoprotective compounds in Paeoniae Radix Rubra. Fluorescein diacetate labelled and MTT assay were applied for screening the hepatoprotective fractions on HepG2 cells
B L Hungund et al.
Alcoholism, clinical and experimental research, 19(2), 374-377 (1995-04-01)
The fate of [14C]ethyl-linoleate (EthLin) after its intravenous administration was investigated in pentobarbital-anesthetized rats. The disappearance of [14C]EthLin from the plasma was very rapid and followed quite closely a biexponential function of time. Fitting of the experimental data to a
A Charakida et al.
The British journal of dermatology, 157(3), 569-574 (2007-07-20)
Acne vulgaris is a major clinical problem; despite a vast array of treatment modalities available for acne, there is considerable dissatisfaction in acne treatment among patients and doctors. Rising antibiotic drug resistance consequent to the widespread use of topical antibiotics
A Napolitano et al.
The Journal of organic chemistry, 65(16), 4853-4860 (2000-08-24)
The reaction of ethyl linoleate (1) with NO(2)(-) in different air-equilibrated acidic media resulted in the formation of complex patterns of products, some of which could be isolated by repeated TLC fractionation and were formulated as the nitroalkenes 2-5, the
M A Refaai et al.
Lipids, 38(3), 269-273 (2003-06-06)
The role of fatty acid ethyl esters (FAEE), the nonoxidative ethanol metabolites, as mediators of alcohol-induced organ damage is increasingly being recognized. FAEE are detectable in the blood and in liver and adipose tissue after ethanol ingestion, and on that
Simona Pichini et al.
Clinical chemistry and laboratory medicine, 52(8), 1179-1185 (2014-03-13)
Ethyl glucuronide (EtG) measurement in neonatal meconium has emerged as a reliable marker to objectively assess prenatal exposure to maternal ethanol complementary to fatty acid ethyl ester (FAEEs) measurement. The detection of EtG in meconium is currently a lengthy, difficult
Obie Farobie et al.
Bioresource technology, 191, 306-311 (2015-05-26)
In this study, biodiesel production under supercritical conditions among methanol, ethanol, and tert-butyl methyl ether (MTBE) was compared in order to elucidate the differences in their reaction behavior. A continuous reactor was employed, and experiments were conducted at various reaction
C F Bearer et al.
Alcoholism, clinical and experimental research, 23(3), 487-493 (1999-04-09)
Fetal alcohol syndrome, fetal alcohol effects, alcohol-related neurodevelopmental disorder, and alcohol-related birth defects, all terms referring to the spectrum of consequences of in utero exposure to ethanol, are a major public health burden. There is currently no laboratory test to
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