Showing 1-30 of 124 results for "64-72-2"
Elizabeth Brazeau et al.
Journal of neurovirology, 16(2), 133-140 (2010-03-30)
Varicella-zoster virus infects multiple human and monkey cells in culture. The mode of cell death appears to be autophagy or apoptosis. Analysis of VZV-infected human melanoma (MeWo) cells revealed that Bcl-2 mRNA and protein levels were decreased significantly 64 and...
Rohit Bhargava et al.
American journal of clinical pathology, 123(6), 889-895 (2005-05-19)
We studied HER-2/neu (HER-2) and topoisomerase IIa (topo2a) amplification (using chromogenic in situ hybridization) and overexpression (immunohistochemical analysis) in 113 invasive breast carcinomas. A gene copy number/chromosome 17 copy number ratio of 2.0 or higher indicated amplification. A topo2a/chromosome 17...
Andrius Baskys et al.
Neuropharmacology, 49 Suppl 1, 146-156 (2005-07-19)
Group I metabotropic glutamate receptor (mGluR) agonist DHPG reduced nerve cell death caused by their exposure to NMDA ("neuroprotective effect") and attenuated NMDA receptor-mediated currents [Blaabjerg, M., Baskys, A., Zimmer, J., Vawter, M. P., 2003b. Changes in hippocampal gene expression...
Li-guang Liu et al.
The Journal of antibiotics, 66(12), 709-712 (2013-08-29)
No mutant-prevention concentration (MPC) with methicillin-resistant Staphylococcus epidermidis (MRSE) has been reported. The study aimed to evaluate the propensity of vancomycin individually and in combination to prevent MRSE from mutation. A total of 10 MRSE clinical isolates were included in...
Jeong Yun Shim et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 16(12), 1199-1204 (2003-12-19)
Cyclooxygenase is the rate-limiting enzyme that catalyzes the conversion of arachidonic acid to prostaglandins. The inducible form, cyclooxygenase-2, is known to be overexpressed in various human cancers including the colon, stomach, and urinary bladder. In this study, we evaluated the...
Yan Fang et al.
Human reproduction (Oxford, England), 26(5), 1252-1258 (2011-02-23)
The interaction between p53 and human double minute 2 (HDM2) plays an important role in apoptosis; therefore, functional polymorphisms in these genes might have adverse effects in early pregnancy. In this study, we investigated whether p53 codon 72 and HDM2...
J K Bentley et al.
Journal of neurochemistry, 76(4), 1252-1263 (2001-02-22)
Nerve growth factor (NGF) has been shown to increase cyclic AMP in PC12 cells and to potentiate the actions of other agents that raise cyclic AMP. In our studies, NGF causes over 50% loss of PDE 2 activity (cyclic GMP-stimulated...
D G Evans et al.
Journal of medical genetics, 32(6), 470-474 (1995-06-01)
We report a family with type 2 neurofibromatosis and late onset tumours. Five members of this family have developed hearing loss late in life, two of whom have only been shown to have the diagnosis in their seventies, and three...
Lucas R Cusumano et al.
Cardiovascular and interventional radiology, 43(1), 29-36 (2019-09-01)
To examine the characteristics of recurrent pulmonary arteriovenous malformations (PAVMs) and compare the success of proximal versus distal embolization technique for treatment of recanalized PAVMs. Between July 2007 and October 2018, 26 consecutive patients underwent embolization of 64 previously treated...
R V Knox et al.
Theriogenology, 82(3), 379-386 (2014-06-04)
Previous studies have shown that triptorelin gel (TG) given intravaginally in gel form is effective for advancing the time of ovulation in weaned sows. Three experiments were performed to determine the effects of altering the dose and timing of administration...
Zhuo Chen et al.
Bioorganic & medicinal chemistry, 16(3), 1337-1344 (2007-11-13)
Saxifraga stolonifera, an evergreen dicotyledon, has been identified as an important resource in Chinese medicine due to its anticancer activity. In the present report, chemical components of S. stolonifera (L) Meeb which is found in Guizhou province were investigated. Ten...
D Saranath et al.
Gynecologic oncology, 86(2), 157-162 (2002-07-30)
The HPV16/18 code for an oncoprotein-E6, which binds to p53 tumor suppressor protein and degrades the protein via ubiquitination. A common polymorphism of p53 in exon 4 codon 72, resulting in either proline (Pro) or arginine (Arg), affects HPV16/18 E6-mediated...
Abdel-Rahman B A El-Gazzar et al.
Bioorganic & medicinal chemistry letters, 19(13), 3392-3397 (2009-06-02)
4-Substituted-pyrido[2,3-d]pyrimidin-4(1H)-ones 4a-c were synthesized by oxidation of 4-substituted-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones 3a-c which were in turn prepared from arylidenemalononitriles 1a-c and 6-aminothiouracil 2. The reactivity of compounds 4a-c towards some reagents such as formamide, carbon disulfide, urea, thiourea, formic and acetic acids were...
R Gershoni-Baruch et al.
European journal of cancer (Oxford, England : 1990), 36(18), 2313-2316 (2000-11-30)
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with reduced enzyme activity, hyperhomocysteinaemia and increased risk for atherosclerosis in homozygotes. We examined the frequency of this mutation and its association with disease pattern in 491 Jewish women...
J Hillegass et al.
Journal of dairy science, 91(11), 4226-4237 (2008-10-24)
Our objectives were to compare reproductive responses of dairy cows receiving timed artificial insemination (AI) either at 48 or 72 h after induction of luteolysis and supplemented or not with estradiol cypionate (ECP). Holstein cows (971) had their estrous cycles...
Donatella Boschi et al.
Journal of medicinal chemistry, 49(10), 2886-2897 (2006-05-12)
The synthesis and study of the antioxidant and vasodilator properties of a new class of phenols able to release nitric oxide are described. The products were designed through a symbiotic approach using selected phenols and selected nitrooxy and furoxan NO-donors...
S A Short et al.
The Journal of biological chemistry, 271(9), 4978-4987 (1996-03-01)
The importance of eight nucleoside 2'-deoxyribosyltransferase residues for catalysis was investigated by site-directed mutagenesis. Each residue was selected because of its proximity to nucleophile Glu-98 or on its potential contribution to intrinsic protein fluorescence. Mutation of Asp-72, Asp-92, Tyr-7, Trp-12...
Stojan Peric et al.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 32(2), 106-109 (2014-01-09)
Myotonic dystrophy type 1 (DM1) is the most common form of muscular dystrophy in adults. It affects many organs and systems besides muscle. Aim of this study was to assess frequency of erectile dysfunction (ED) and hypogonadism, the correlation between...
Steven N Leonard
PloS one, 7(7), e42103-e42103 (2012-08-01)
Continued pressure from glycopeptide use has led to non-susceptible strains of Staphylococcus aureus including heterogeneously vancomycin-intermediate S. aureus (hVISA). Infections with hVISA are associated with poor patient outcomes, thus incentivizing novel treatments. Evidence suggests that vancomycin and anti-staphylococcal penicillin susceptibility...
Dennis M McNamara et al.
Circulation, 107(12), 1598-1602 (2003-04-02)
Significant variation exists within the endothelial nitric oxide synthase (NOS3) gene that may influence cardiovascular risk. The Asp298 variant of NOS3 has a shorter half-life in endothelial cells. Given the importance of nitric oxide in the heart failure syndrome, we...
I Golovleva et al.
Carcinogenesis, 18(4), 645-647 (1997-04-01)
Nasopharyngeal carcinoma, which is very frequent in southern China, has in previous investigations been found to be associated with a number of risk factors, including a disease susceptibility gene linked to the HLA-region, p53 alleles and deletions of the chromosome...
J Pyo et al.
Journal of dairy science, 103(5), 4236-4251 (2020-03-17)
This study evaluated how feeding colostrum- or a colostrum-milk mixture for 3 d postnatal affects plasma glucagon-like peptide-2 (GLP-2), serum insulin-like growth factor-1 (IGF-1), and small intestinal histomorphology in calves. Holstein bulls (n = 24) were fed colostrum at 2...
R N Weinreb et al.
Investigative ophthalmology & visual science, 38(13), 2772-2780 (1998-01-07)
To identify matrix metalloproteinases (MMPs) released by ciliary smooth muscle cells in vitro and to determine whether MMP release is altered by exposure to prostaglandins (PGs). Human ciliary smooth muscle cells were grown to confluence in monolayer cultures and treated...
Eun-Kyung Kim et al.
Journal of agricultural and food chemistry, 52(2), 196-200 (2004-01-22)
Corn silage was dried, ground, and then extracted with 0.1 M ethylenediaminetetraacetic acid. The filtrate was applied to a FumoniTest immunoaffinity column. Fumonisins were derivatized with naphthalene-2,3-dicarboxaldehyde, separated on a C(18) liquid chromatographic column, and detected by fluorescence. The detection...
Yunsur Cevik et al.
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 16(2), 125-129 (2010-06-03)
The aim of the study was to investigate the role and importance of the urine trypsinogen-2 dipstick test in the differential diagnosis of acute pancreatitis in the Emergency Department and to compare results with those of conventional tests. The study...
Ching-Wan Lam et al.
Clinica chimica acta; international journal of clinical chemistry, 364(1-2), 256-259 (2005-09-13)
Chylomicronemia syndrome can be caused by 2 autosomal recessive disorders - lipoprotein lipase (LPL) deficiency and apolipoprotein C-II (apo C-II) deficiency. We described 2 siblings with chylomicronemia syndrome of a consanguineous family. To determine the molecular basis of chylomicronemia syndrome...
A Veeraiah
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 147, 212-224 (2015-04-05)
The vibrational and electronic properties of 2-(bromoacetyl)benzo(b)furan have been studied in the ground state using experimental techniques (FT-IR, FT-Raman and UV) and density functional theory (DFT) employing B3LYP exchange correlation with the 6-31G(d,p) basis set. The theoretically calculated optimized parameters...
Hsiao-Li Chuang et al.
The Journal of veterinary medical science, 71(2), 163-169 (2009-03-06)
Epidemiological investigations suggest that increased age is associated with susceptibility to infection. Pseudomonas aeruginosa (P. aeruginosa) infection and associated exotoxin A (PEA) toxicity have been reported in hospitalized elderly patients and young children with cystic fibrosis. The present study investigated...
Xian-Li Yang et al.
Huan jing ke xue= Huanjing kexue, 31(6), 1670-1674 (2010-08-12)
According to the frequency of contamination accident for organic compounds in recent years, two kinds of organophosphorus pesticides dichlorvos and omethoate, as the simulated organic pollutants, were rapidly eliminated using spraying hydroxyl radical produced by strong electric-field ionization discharge method...
Rajeev Rai et al.
Parasitology, 144(14), 1912-1921 (2017-07-25)
Leishmaniasis develops after parasites establish themselves as amastigotes inside mammalian cells and start replicating. As relatively few parasites survive the innate immune defence, intracellular amastigotes spreading towards uninfected cells is instrumental to disease progression. Nevertheless the mechanism of Leishmania dissemination...

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