Showing 1-30 of 404 results for "68-12-2"
Akanksha Jindal et al.
Journal of labelled compounds & radiopharmaceuticals, 57(7), 463-469 (2014-06-27)
While [(11)C]palmitate continues to be a promising tracer for cardiovascular Positron Emission Tomography (PET) imaging, unfavourable logistics due to the short half-life of (11)C (20 min) and cumbersome labeling methodologies are the major impediments that limit its widespread use. In order...
Zi-Bo Li et al.
European journal of nuclear medicine and molecular imaging, 35(6), 1100-1108 (2008-01-22)
We and others have reported that (18)F- and (64)Cu-labeled arginine-glycine-aspartate (RGD) peptides allow positron emission tomography (PET) quantification of integrin alpha(v)beta(3) expression in vivo. However, clinical translation of these radiotracers is partially hindered by the necessity of cyclotron facility to...
B Rikhof et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 20(9), 1582-1588 (2009-03-12)
Patients with a gastrointestinal stromal tumour (GIST) suffering from non-islet cell tumour-induced hypoglycaemia (NICTH), being associated with increased plasma levels of pro-insulin-like growth factor (IGF)-IIE[68-88], have been reported occasionally. We studied the clinical relevance of pro-IGF-IIE[68-88] and other IGF-related proteins...
Paula Stice et al.
Journal of neural engineering, 4(2), 42-53 (2007-04-06)
The objective of this study was to test the hypothesis that neural implants with reduced cross-sectional areas will have less glial scarring associated with implantation injury in long-term experiments. In this study, we implanted nine adult rats with two different...
Jian-Hai Ding et al.
Journal of Asian natural products research, 19(8), 780-785 (2016-11-29)
Three new drimane sesquiterpenoids, 12-hydroxyalbrassitriol (1), drim-8(12)-en-6β,7α, 9α,11-tetraol (2), and drim-68(12)-dien-9α,11-diol (3), along with one known analog albrassitriol (4), were isolated from cultures of the tin mine tailings-associated fungus Penicillium sp. The new structures were determined on the basis of...
Stefan Zeuzem et al.
The New England journal of medicine, 370(21), 1993-2001 (2014-05-06)
In clinical trials, treatment with a combination of the nucleotide polymerase inhibitor sofosbuvir and the antiviral drug ribavirin was associated with high response rates among patients with hepatitis C virus (HCV) genotype 2 infection, with lower response rates among patients...
Walter Rachinger et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(3), 347-353 (2015-01-31)
Meningiomas are known to express somatostatin receptor 2 (SSTR2). PET using the SSTR2 analog (68)Ga-DOTATATE has recently been introduced for imaging of meningiomas. However, a systematic correlation between (68)Ga-DOTATATE uptake, SSTR2 expression, and histology (including tumor-free scar tissue) is still...
Shannon Humphrey et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 41(9), 1060-1067 (2015-08-01)
A 3-dimensional approach to facial rejuvenation restores volume lost over time. Hyaluronic acid (HA) filling agents provide long-lasting correction with minimal side effects and a high level of patient satisfaction. The newest HA formulation is a 20-mg/mL smooth cohesive filler...
Susan D Richman et al.
Analytical cellular pathology (Amsterdam), 34(1-2), 61-66 (2011-04-13)
KRAS mutation status is established as a predictive biomarker of benefit from anti-EGFr therapies. Mutations are normally assessed using DNA extracted from one formalin-fixed, paraffin-embedded (FFPE) tumor block. We assessed heterogeneity of KRAS and BRAF mutation status intra-tumorally (multiple blocks...
Kiran Turaka et al.
Clinical & experimental ophthalmology, 41(3), 239-243 (2012-09-11)
Aromatase inhibitors are frequently used as an adjuvant therapy in the treatment of breast cancer. We observed that several patients taking aromatase inhibitors presented with severe dry eye symptoms, and we investigated whether there is a relationship between aromatase inhibitors...
M Nurhalim Shahib et al.
The Journal of reproductive medicine, 51(11), 892-896 (2006-12-15)
To examine the expression of HASH2 in gestational trophoblastic disease (GTD). DNA and RNA were isolated from 54 cases of GTD comprising 27 complete hydatidiform moles (CMs), 12 invasive moles (IvMs), 1 placental site trophoblastic tumor (PSTT) and 14 choriocarcinomas...
Z Su et al.
International journal of obesity (2005), 32(7), 1180-1189 (2008-04-17)
To identify the genes controlling body fat, we carried out a quantitative trait locus (QTL) analysis using C57BL/6J (B6) and 129S1/SvImJ (129) mice, which differ in obesity susceptibility after consuming an atherogenic diet. Mice were fed chow until 8 weeks...
Mehmet Gungor Kaya et al.
Texas Heart Institute journal, 39(4), 500-506 (2012-09-06)
We investigated the prognostic importance of plasma myeloperoxidase levels in patients with ST-elevation myocardial infarction (STEMI) at long-term follow-up, and we analyzed the correlations between plasma myeloperoxidase levels and other biochemical values. We evaluated 73 consecutive patients (56 men; mean...
Jae B Park
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(10), 843-847 (2011-03-08)
Veskamide, enferamide, becatamide, and oretamide are phenolic amides whose analogues are found in plants. In this study, the four amides were prepared by chemical synthesis and their protective effects on H(2)O(2)-induced apoptosis in PC-12 cells were investigated. The syntheses were...
Michael Medinger et al.
Pathology oncology research : POR, 16(3), 295-301 (2010-02-24)
c-kit functions as a tyrosine kinase receptor and represents a target for small molecule kinase inhibitors. The expression pattern for c-kit was studied in different human tumor types to their correlation with prognosis. Paraffin-embedded tumor tissues from 282 patients were...
Ga Young Yoon et al.
Medicine, 94(31), e1274-e1274 (2015-08-08)
To investigate the chest computed tomography (CT) and F-18 fluoro-2-deoxy-D-glucose positron emission tomographic (FDG-PET) findings of posttransplant lymphoproliferative disorder (PTLD) in the thorax.From November 2004 to February 2013, the cases of 12 adult patients (3 female and 9 male, age...
Cristina López et al.
Genes, chromosomes & cancer, 51(9), 881-889 (2012-05-24)
Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults in Western countries. Chromosomal abnormalities commonly found using conventional cytogenetics and FISH are del(11)(q22-23), trisomy 12, del(13)(q14), and del(17)(p13). Trisomy 12 is the most frequent numerical abnormality in CLL....
Hatice Ozer et al.
Diagnostic pathology, 7, 124-124 (2012-09-22)
In many tumors including ovarian cancer, cell proliferation and apoptosis are important in pathogenesis and there are many alterations in most of the genes related to the cell cycle. This study was designed to evaluate immunohistochemistry with apoptotic-antiapoptotic proteins (p53...
M Tanaka et al.
Biochimica et biophysica acta, 1522(1), 62-65 (2001-11-24)
Ghrelin is a novel growth hormone-releasing peptide isolated from rat stomach. In the present study, we report expression of a ghrelin gene-derived transcript (GGDT) in the mouse testis. Analysis of GGDT cDNA revealed that the 68 bp sequence at the...
Derya Gumurdulu et al.
Endocrine research, 29(4), 465-472 (2003-12-20)
c-erbB-2 expression has been found to be an important prognostic parameter in various types of tumors, but the role played by this oncoprotein in thyroid tumors is still controversial. This study is designed to investigate c-erbB-2 expression in different types...
Masaaki Mori et al.
Antimicrobial agents and chemotherapy, 59(2), 1004-1013 (2014-12-03)
The aim of this study was to investigate the pharmacokinetics, safety, and tolerability of voriconazole following intravenous-to-oral switch regimens used with immunocompromised Japanese pediatric subjects (age 2 to <15 years) at high risk for systemic fungal infection. Twenty-one patients received...
Michiko Gamanuma et al.
Cellular signalling, 15(6), 565-574 (2003-04-19)
Full-length cDNAs of human cyclic nucleotide phosphodiesterase 8B (PDE8B) were isolated. Enzymatic characteristics of a dominant variant encoding a protein of 885 residues (PDE8B1) were compared with those of PDE8A1. The recombinant PDE8A1 and PDE8B1 proteins of an entire form...
Eduardo Martínez-Morillo et al.
Clinical chemistry and laboratory medicine, 53(10), 1575-1584 (2015-02-27)
Brain injury is a medical emergency that needs to be diagnosed and treated promptly. Several proteins have been studied as biomarkers of this medical condition. The aims of this study were to: 1) evaluate the selectivity and precision of a...
G Dale et al.
Lancet (London, England), 1(8112), 347-349 (1979-02-17)
Acetylcholinesterase (AChE) activity was measured in rectal biopsy specimens obtained from 68 children aged between 2 days and 14 1/2 years in whom Hirschsprung's disease was suspected. The diagnosis was subsequently established in 12; in these, the mean AChE activity...
Lih Kin Khor et al.
Head & neck, 38(4), E76-E80 (2015-08-15)
Increased somatostatin receptor (SSTR) expression in patients with undifferentiated nasopharyngeal carcinoma (NPC) has been demonstrated with receptor autoradiography, (111) In-Octreotide scintigraphy, and (68) Ga-DOTA-TOC positron emission tomography (PET)/CT imaging. We sought to compare and correlate the uptake of fluorodeoxyglucose (FDG)...
Bo Li et al.
Zhonghua fu chan ke za zhi, 44(7), 514-517 (2009-12-05)
To investigate the expression and significance of elastin and fibulin-5 in anterior vaginal tissue of women with pelvic organ prolapse (POP). Between November 2006 and June 2008, 68 patients with POP underwent surgical treatment in Shengjing Hospital of China Medical...
M Amini et al.
Pharmaceutica acta Helvetiae, 73(6), 303-306 (1999-08-12)
A rapid, simple and sensitive high-performance liquid chromatographic method for the determination of captopril in plasma has been developed. Captopril is derivatized with a new reagent, 2-bromo-2'-acetonaphthone to form a product that showed ultraviolet-absorbing properties. For plasma samples, the protein...
R Morishita et al.
The Journal of biological chemistry, 270(49), 29469-29475 (1995-12-08)
We have determined the primary structure of a novel gamma subunit (gamma 12, previously designated gamma S1) of G protein purified from bovine spleen. The mature gamma 12 protein composed of 68 amino acids had acetylated serine at the N...
Vincent Pialoux et al.
Free radical biology & medicine, 46(2), 321-326 (2008-11-26)
The aim of this study was to investigate the relations among reactive oxygen species (ROS), hypoxia inducible factor (HIF-1 alpha) gene expression, HIF-1 alpha target gene erythropoietin (EPO), and vascular endothelium growth factor (VEGF) in humans. Five healthy men (32+/-7...
Hemal Mehta et al.
The British journal of ophthalmology, 102(4), 479-482 (2017-08-06)
To determine whether early vision gains predict long-term visual outcomes in the BEVORDEX randomised clinical trial of bevacizumab or dexamethasone implants for diabetic macular oedema. Post hoc analysis of 68 study eyes (77%) that completed 2 years follow-up of the...

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