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Roland Schmitt et al.
Journal of immunology (Baltimore, Md. : 1950), 193(1), 317-326 (2014-05-23)
IgA nephropathy (IgAN) is characterized by mesangial cell proliferation and extracellular matrix expansion associated with immune deposits consisting of galactose-deficient polymeric IgA1 and C3. We have previously shown that IgA-binding regions of streptococcal M proteins colocalize with IgA in mesangial
Sam Wouters et al.
Journal of chromatography. A, 1355, 253-260 (2014-06-30)
A microfluidic membrane suppressor has been constructed to suppress ions of alkaline mobile-phases via an acid-base reaction across a sulfonated poly(tetrafluoroethylene)-based membrane and was evaluated for anion-exchange separations using conductivity detection. The membrane was clamped between two chip substrates, accommodating
Damiano Carbonari et al.
Toxicology letters, 231(2), 205-212 (2014-06-27)
This study investigated the effect of polymorphic genes GSTT1, GSTM1, GSTA1, EHPX1, NQO1, CYP2E1, CYP1A and MPO on the urinary concentrations and ratio (R) of the benzene metabolites trans,trans-muconic acid (t,t-MA) and S-phenyl mercapturic acid (S-PMA) in 301 oil refinery
Shuiliang Wang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 981-982, 1-8 (2015-01-17)
An accelerated solvent extraction (ASE)-solid-phase extraction (SPE)-liquid chromatography with electrospray ionization-tandem mass spectrometry (ASE-SPE-LC-ESI-MS/MS) methodology was developed for the extraction, cleanup and quantification of ultra-trace organic acids in Masson pine (Pinus massoniana L.) tissues. The separation was carried out on
Chia-Hui Lee et al.
Nanoscale research letters, 9(1), 250-250 (2014-06-12)
Nanotopography modulates the physiological behavior of cells and cell-cell interactions, but the manner of communication remains unclear. Cell networking (syncytium) of astroglia provides the optimal microenvironment for communication of the nervous system. C6 glioma cells were seeded on nanodot arrays
A Polder et al.
The Science of the total environment, 488-489, 252-260 (2014-05-20)
In Tanzania fish is one of the most important protein sources for the rapidly increasing population. Wild fish is threatened by overfishing and pollution from agriculture, industries, mining, household effluents and vector control. To monitor possible implications for public health
Martin F Reiner et al.
Thrombosis and haemostasis, 113(1), 177-184 (2014-09-19)
Venous thromboembolism (VTE) is a leading cause of cardiovascular death. Omega-3 fatty acids (n-3 FA) exhibit protective effects against cardiovascular disease. Others and our group have reported that the plant-derived n-3 FA alpha-linolenic acid (ALA) displays antiinflammatory, anticoagulant and antiplatelet
Jordan L Woehl et al.
Journal of immunology (Baltimore, Md. : 1950), 193(12), 6161-6171 (2014-11-09)
The pathogenic bacterium Staphylococcus aureus actively evades many aspects of human innate immunity by expressing a series of small inhibitory proteins. A number of these proteins inhibit the complement system, which labels bacteria for phagocytosis and generates inflammatory chemoattractants. Although
Michael Schinhammer et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 1882-1893 (2013-03-19)
Biodegradable metals offer great potential in circumventing the long-term risks and side effects of medical implants. Austenitic Fe-Mn-C-Pd alloys feature a well-balanced combination of high strength and considerable ductility which make them attractive for use as degradable implant material. The
Claudio Meléndez-González et al.
Chemistry & biodiversity, 12(1), 133-147 (2015-02-03)
Bioactivity-directed fractionation of the organic mycelium extract of the endophytic fungus Acremonium camptosporum W. Gams (Clavicipitaceae), isolated from the leaves of Bursera simaruba (Burseraceae), led to the isolation of six major heterodimeric polyketides, including one not previously characterized acremoxanthone derivative.
Cameron L Nemeth et al.
Tissue engineering. Part A, 20(21-22), 2817-2829 (2014-04-23)
We have examined the effects of surface nanotopography and hyaluronic acid (HA) on in vitro chondrogenesis of dental pulp stem cells (DPSCs). Ultraviolet-assisted capillary force lithography was employed to fabricate well-defined nanostructured scaffolds of composite PEG-GelMA-HA hydrogels that consist of
Nathan L Netzer et al.
Angewandte Chemie (International ed. in English), 53(41), 10965-10969 (2014-08-27)
The orientation of metal-organic supercontainer (MOSC) molecules in Langmuir films was systematically studied at the air-water interface. The acidity of the aqueous subphases plays a significant role in tuning the orientation of MOSC molecules in the Langmuir films. Furthermore, Langmuir-Blodgett
Agnieszka Kucharska et al.
The Science of the total environment, 505, 1062-1071 (2014-12-03)
In this study, we investigated the hypothesis whether externally adsorbed and internally deposited flame retardants (FRs) in hair could be distinguished. To this extent, hair samples collected from one volunteer were exposed under controlled conditions to phosphate FR (PFR) and
Noelia Carmona-Vicente et al.
Journal of medical virology, 87(4), 675-682 (2015-02-07)
Genotype II.4 noroviruses (NoVs) are a leading cause of epidemic acute gastroenteritis in children and adults worldwide. The prevalence of different NoV genotypes causing outbreaks and sporadic cases of acute gastroenteritis in the region of Valencia, Spain, during a 4-year
Manuela Rollini et al.
Bioprocess and biosystems engineering, 37(12), 2587-2595 (2014-06-26)
This study investigated the effect of enzymatic and combined alkaline-enzymatic pretreatments on chemical composition and methane production from ensiled sorghum forage. Four commercial enzymatic preparations were tested and the two yielding the highest sugars release were added to evaluate any
Ye-Jin Jung et al.
Archives of pharmacal research, 38(2), 178-185 (2014-04-22)
The stems of Zea mays L., otherwise known as cornstalks, were extracted with 80 % aqueous MeOH, and the concentrated extract was successively partitioned with ethyl acetate (EtOAc), normal butanol, and water. From the EtOAc fraction, a new lignan along
Alessio Innocenti et al.
Bioorganic & medicinal chemistry letters, 15(3), 567-571 (2005-01-25)
The inhibition of five human carbonic anhydrase (hCA, EC isozymes; the cytosolic hCA I and II, the membrane-bound hCA IV, the mitochondrial hCA V, and the tumor-associated, transmembrane hCA IX, with anions isosteric and isoelectronic with sulfate, nitrate, and
Mark S Singer et al.
Clinica chimica acta; international journal of clinical chemistry, 440, 72-78 (2014-12-03)
SULF2 is an extracellular sulfatase that acts on heparan sulfate proteoglycans and modulates multiple signaling pathways. It is normally bound to the cell surface but can be released into the medium of cultured cells. SULF2 is known to be increased
Víctor Sanabria-Ayala et al.
Parasitology research, 114(1), 55-64 (2014-10-03)
Previous studies demonstrated that antibodies against triosephosphate isomerase of Taenia solium (TTPI) can alter its enzymatic catalysis. In the present study, we used antibodies produced against the NH2-terminal region of TTPI (1/3NH2TTPI) and the phage display technology to find target
Zhongxin Zhou et al.
Biotechnology and applied biochemistry, 61(6), 716-723 (2014-03-29)
Monascus pigment has traditionally been produced by the fermentation of Monascus using rice powder or glucose as a culture substrate. Submerged fermentation can produce stable Monascus pigment yield and control the accumulation of the by-product, citrinin, which can then be
Grażyna E Sroga et al.
PloS one, 10(2), e0117240-e0117240 (2015-02-14)
To better understand some aspects of bone matrix glycation, we used an in vitro glycation approach. Within two weeks, our glycation procedures led to the formation of advanced glycation end products (AGEs) at the levels that corresponded to approx. 25-30
Alessandra Ricciardi et al.
Vaccine, 33(2), 346-353 (2014-12-03)
Schistosomiasis is the most important human helminth infection due to its impact on public health. Worldwide, schistosomiasis is estimated to infect at least 200 million individuals while 700 million are at risk. The clinical manifestations are chronic and significantly decrease
Deirdre A Costello et al.
Journal of virology, 89(1), 350-360 (2014-10-17)
Influenza A virus strains adapt to achieve successful entry into host species. Entry is mediated by the viral membrane protein hemagglutinin (HA), which triggers membrane fusion and genome release under acidic conditions in the endosome. In addition to changes in
Jatinder Kumar et al.
PloS one, 9(6), e98696-e98696 (2014-06-18)
Fourteen saxicolous lichens from trans-Himalayan Ladakh region were identified by morpho-anatomical and chemical characteristics. The n-hexane, methanol and water extracts of the lichens were evaluated for their antioxidant capacities. The lichen extracts showing high antioxidant capacities and rich phenolic content
Miloslav Kverka et al.
Biomaterials, 35(22), 5886-5896 (2014-04-29)
A two-component CD20 (non-internalizing) receptor crosslinking system based on the biorecognition of complementary coiled-coil forming peptides was evaluated. Exposure of B cells to Fab'-peptide1 conjugate decorates the cell surface with peptide1; further exposure of the decorated cells to P-(peptide2)x (P
A Iparraguirre et al.
Journal of chromatography. A, 1360, 57-65 (2014-08-19)
In the present work, a novel analytical method for the simultaneous determination of ten polybrominated diphenyl ethers (PBDEs), eight methoxylated PBDEs (MeO-PBDEs) and seven hydroxylated PBDEs (OH-PBDEs) in soil, lettuce and carrot samples was developed. The procedure was based on
Gubbala V Ramesh et al.
ACS applied materials & interfaces, 6(18), 16124-16130 (2014-09-04)
Although compositional tuning of metal nanoparticles (NPs) has been extensively investigated, possible control of the catalytic performance through bulk-structure tuning is surprisingly overlooked. Here we report that the bulk structure of intermetallic ZrPt3 NPs can be engineered by controlled annealing
C Alfarano et al.
International journal of obesity (2005), 39(2), 312-320 (2014-07-17)
Impaired energy metabolism is the defining characteristic of obesity-related heart failure. The adipocyte-derived peptide apelin has a role in the regulation of cardiovascular and metabolic homeostasis and may contribute to the link between obesity, energy metabolism and cardiac function. Here
Silvia Torrecillas et al.
Fish & shellfish immunology, 42(2), 508-516 (2014-12-03)
The study assesses the effects of dietary concentrated mannan oligosaccharides (cMOS) on fish performance, biochemical composition, tissue fatty acid profiles, liver and posterior gut morphology and gen expression of selected parameters involved on the intestinal immune response and liver lipid
Chang Li et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 75, 8-13 (2014-12-03)
3-monochoropropane-1, 2-diol (3-MCPD) esters from edible oils are considered to be a possible risk factor for adverse effects in human. In the present study, the exposure assessment of 3-MCPD esters to Chinese population was performed. A total of 143 edible
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