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mitochondrial ribosomal protein L53
Human MRPL53 (116540), Mouse Mrpl53 (68499), Rat Mrpl53 (362388), sheep MRPL53 (101118259), naked mole-rat Mrpl53 (101698339), domestic guinea pig Mrpl53 (100735739), fruit fly mRpL53 (3772367), cow MRPL53 (505728), domestic cat MRPL53 (101086471), dog MRPL53 (612261), chicken MRPL53 (420196)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 1p. [provided by RefSeq, Jul 2008

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