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Marilis Rodriguez et al.
PloS one, 9(9), e107727-e107727 (2014-09-17)
Human babesiosis is caused by one of several babesial species transmitted by ixodid ticks that have distinct geographical distributions based on the presence of competent animal hosts. The pathology of babesiosis, like malaria, is a consequence of the parasitaemia which
Balakrishnan Umesh et al.
Poultry science, 94(11), 2805-2815 (2015-10-27)
An improved method for the chromatographic separation and determination of chromium (III) and (VI) [ CRIII AND CRVI: ] in mineral mixtures and feed samples has been developed. The method uses precolumn derivatization using ammonium pyrrolidinedithiocarbamate ( APD: ) followed
Branka Šošić-Jurjević et al.
Toxicology and applied pharmacology, 278(2), 124-134 (2014-05-06)
We previously reported that genistein (G) and daidzein (D) administered subcutaneously (10mg/kg) induce changes in the angio-follicular units of the thyroid gland, reduce concentration of total thyroid hormones (TH) and increase thyrotropin (TSH) in serum of orchidectomized middle-aged (16-month-old) rats.
Sonia Lefnaoui et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 23(6), 698-711 (2015-12-25)
A pregelatinized starch (PGS) was derivatized with sodium chloroacetate (SCA) in alcoholic medium under alkaline condition to produce carboxymethyl pregelatinized starch (CMPGS) with various degrees of substitution (DS). Influence of the molar ratio of SCA to the glucopyranose units (SCA/GU)
Ruben Magni et al.
Journal of translational medicine, 13, 346-346 (2015-11-06)
Prompt antibiotic treatment of early stage Lyme borreliosis (LB) prevents progression to severe multisystem disease. There is a clinical need to improve the diagnostic specificity of early stage Lyme assays in the period prior to the mounting of a robust
Jie Xiao et al.
Journal of agricultural and food chemistry, 63(47), 10263-10270 (2015-11-06)
Kafirin nanoparticle-stabilized Pickering emulsions (KPEs) were used to encapsulate curcumin. The stability of KPEs under processing conditions and their protective effects against photo-oxidation of curcumin and lipid oxidation of oil in emulsions, as well as the digestion profiles in gastrointestinal
Anna Sankiewicz et al.
Analytical biochemistry, 469, 4-11 (2014-10-15)
We have developed a new method for highly selective determination of the ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) concentration using a surface plasmon resonance imaging (SPRI) technique and two different biosensors. UCH-L1 was captured from a solution by immobilized specific rabbit
Jaime Gómez-Gutiérrez et al.
Diseases of aquatic organisms, 116(3), 213-225 (2015-10-28)
Histophagous ciliates of the genus Pseudocollinia cause epizootic events that kill adult female krill (Euphausiacea), but their mode of transmission is unknown. We compared 16S rRNA sequences of bacterial strains isolated from stomachs of healthy krill Nyctiphanes simplex specimens with
A F Hernández-Pérez et al.
Bioresource technology, 200, 1085-1088 (2015-12-01)
Biotechnological production of xylitol is an attractive route to add value to a sugarcane biorefinery, through utilization of the hemicellulosic fraction of sugarcane straw, whose availability is increasing in Brazil. Herein, supplementation of the sugarcane straw hemicellulosic hydrolyzate (xylose 57gL(-1))
Rose M Jones et al.
Extremophiles : life under extreme conditions, 17(5), 841-850 (2013-07-26)
Three obligately heterotrophic bacterial isolates were identified as strains of a proposed novel species of extremely acidophilic, mesophilic Alphaproteobacteria, Acidocella aromatica. They utilized a restricted range of organic substrates, which included fructose (but none of the other monosaccharides tested), acetate
Hisako Hikiji et al.
Journal of materials science. Materials in medicine, 25(6), 1531-1538 (2014-02-28)
Rapid and efficient animal models are needed for evaluating the effectiveness of many new candidate bone regenerative materials. We developed an in vivo model screening for calvarial bone regeneration in lipopolysaccharide (LPS)-treated mice, in which materials were overlaid on the
Sema Demirci Çekiç et al.
Analytica chimica acta, 865, 60-70 (2015-03-04)
A colourimetric sensor capable of simultaneously measuring oxidative status (OS) in terms of the hazard produced by reactive oxygen species (ROS) and antioxidant activity (AOA) in regard to ROS-scavenging ability of antioxidant compounds was developed. The coloured cationic semi-quinone derivatives
Meng-Ting Huang et al.
Taiwanese journal of obstetrics & gynecology, 54(1), 48-53 (2015-02-14)
To evaluate if hyaluronic acid (HA)-bound spermatozoa surpassed conventional microscopy-selected spermatozoa in the status of sperm DNA integrity by acridine orange (AO) fluorescence staining. Spermatozoa obtained from couples with indication for the intracytoplasmic sperm injection (ICSI) procedure due to male
Tatsuya Higashi et al.
Journal of pharmaceutical and biomedical analysis, 117, 155-162 (2015-09-12)
The analysis of changes in the brain neurosteroid (NS) levels due to various stimuli can contribute to the elucidation of their physiological roles, and the discovery and development of new antipsychotic agents targeting neurosteroidogenesis. We developed methods for the differential
Kyung Min Jeong et al.
Archives of pharmacal research, 38(12), 2143-2152 (2015-11-05)
Deep eutectic solvents (DESs) were investigated as tunable, environmentally benign, yet superior extraction media to enhance the extraction of anthocyanins from grape skin, which is usually discarded as waste. Ten DESs containing choline chloride as hydrogen bond acceptor combined with
Elenaz Naderkhani et al.
Journal of pharmaceutical sciences, 103(2), 661-668 (2014-01-08)
The antiviral drug acyclovir (ACV) suffers from poor solubility both in lipophilic and hydrophilic environment, leading to low and highly variable bioavailability. To overcome these limitations, this study aimed at designing mucoadhesive ACV-containing liposomes to improve its permeability. Liposomes were
Poonam Dharmani et al.
PloS one, 8(3), e58671-e58671 (2013-03-14)
Studies assessing the effect and mechanism of probiotics on diseases of the upper gastrointestinal tract (GI) including gastric ulcers are limited despite extensive work and promising results of this therapeutic option for other GI diseases. In this study, we investigated
Apexa Patel et al.
Journal of chromatographic science, 52(10), 1294-1301 (2013-12-04)
A sensitive, selective, precise and stability indicating a high-performance thin layer chromatographic method for the analysis of rufinamide (Rf) in bulk drug and its formulations was developed and validated. The method employed thin layer chromatography aluminum plates precoated with silica
Hao-Wen Ko et al.
Macromolecular rapid communications, 36(5), 439-446 (2015-01-27)
Multi-component polymer nanomaterials have attracted great attention because of their applications in areas such as biomedicine, tissue engineering, and organic solar cells. The precise control over the morphologies of multi-component polymer nanomaterials, however, is still a great challenge. In this
Jay W Hooper et al.
Science translational medicine, 6(264), 264ra162-264ra162 (2014-11-28)
Polyclonal immunoglobulin-based medical products have been used successfully to treat diseases caused by viruses for more than a century. We demonstrate the use of DNA vaccine technology and transchromosomal bovines (TcBs) to produce fully human polyclonal immunoglobulins (IgG) with potent
Charmion I Cruickshank-Quinn et al.
PloS one, 9(7), e101855-e101855 (2014-07-10)
Cigarette smoke exposure is linked to the development of a variety of chronic lung and systemic diseases in susceptible individuals. Metabolomics approaches may aid in defining disease phenotypes, may help predict responses to treatment, and could identify biomarkers of risk
Hamdy Abdelkader et al.
The Journal of pharmacy and pharmacology, 66(10), 1439-1450 (2014-06-20)
The solid-state interactions of fused mixtures nimesulide (ND) with polyethylene glycol (PEG) 4000, urea or mannitol were studied through constructing thaw-melt phase equilibrium diagrams. The solid-state characteristics were investigated using differential scanning calorimetry (DSC) and X-ray diffraction (XRD). Various types
Theresa A Isbell et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 980, 65-71 (2015-01-16)
The determination of morphine and its isobaric metabolites morphine-3-beta-d-glucuronide (M3G) and morphine-6-beta-d-glucuronide (M6G) is useful for therapeutic drug monitoring and forensic identification of drug use. In particular, capillary electrophoresis with mass spectrometry (CE-MS) represents an attractive tool for opioid analysis.
Anita Aranyi et al.
Journal of chromatography. A, 1387, 123-133 (2015-02-18)
The direct separation of the enantiomers of 1-(α-aminoarylmethyl)-2-naphthol, 1-(α-aminoalkyl)-2-naphthol, 2-(α-aminoarylmethyl)-1-naphthol analogues and 2-(1-amino-2-methylpropyl)-1-naphthol) was investigated in supercritical fluid chromatography. Five commercially available chiral stationary phases based on immobilized polysaccharide chiral selectors (Chiralpak IA, IB, IC, ID and IE) were evaluated.
Cuiping Liu et al.
Arthritis research & therapy, 17, 340-340 (2015-11-27)
The programmed cell death 1 (PD-1) protein is a critical regulator of T-cell activation and is also an important therapeutic target for autoimmune diseases. Little is known about the regulation and functional properties of the soluble PD-1 (sPD-1) variant. The
Zhenhuan Guo et al.
Science signaling, 7(354), rs7-rs7 (2014-12-04)
E-cadherin-mediated cell-cell adhesion and signaling plays an essential role in development and maintenance of healthy epithelial tissues. Adhesiveness mediated by E-cadherin is conferred by its extracellular cadherin domains and is regulated by an assembly of intracellular adaptors and enzymes associated
Tomohiro Hosoya et al.
PloS one, 9(9), e108360-e108360 (2014-10-01)
Lactobacillus helveticus SBT2171 (LH2171) is a lactic acid bacterium with high protease activity and used in starter cultures in the manufacture of cheese. We recently reported that consumption of cheese manufactured using LH2171 alleviated symptoms of dextran sodium sulfate (DSS)-induced
Sara Triñanes et al.
Journal of chromatography. A, 1420, 35-45 (2015-10-18)
The development and performance evaluation of a method for the simultaneous determination of six pharmaceuticals belonging to the class of non-steroidal anti-inflammatory drugs (NSAIDs) which present high selectivity for the cyclooxygenase (COX)-2 isoform of COX (COXIBs) in environmental waters are
Shewit Kalayou et al.
Cell biology and toxicology, 30(6), 361-376 (2014-11-25)
The mycotoxin alternariol (AOH) is an important contaminant of fruits and cereal products. The current study sought to address the effect of a non-toxic AOH concentration on the proteome of the steroidogenic H295R cell model. Quantitative proteomics based on stable
J J MacAskill et al.
Food chemistry, 175, 543-548 (2015-01-13)
A high performance liquid chromatography (HPLC) method was developed to assay nitropropanoyl glucosides in the nuts of karaka (Corynocarpus laevigatus) a traditional food of New Zealand Māori. Levels of glucosides, measured as 3-nitropropanoic acid, ranged from 50.25 to 138.62 g
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