Showing 1-30 of 154 results for "70-47-3"
Pussadee Tangwatcharin et al.
Food science of animal resources, 39(6), 863-876 (2020-01-18)
The thermal-death times of Listeria monocytogenes were determined in inoculated restructured goat steak at 60°C, 65°C, and 70°C of sous-vide temperatures. D-values of L. monocytogenes in inoculated restructured goat steak ranged from 7.27 min at 60°C to 0.46 min at...
S H Zaidi et al.
The Journal of biological chemistry, 270(29), 17292-17298 (1995-07-21)
The central nervous system deposition by neurons and glia of beta A4 amyloid protein is an important contributing factor to the development of Alzheimer's disease. Amyloidogenic cells overexpress amyloid precursor protein (APP) mRNAs suggesting a transcriptional or post-transcriptional defect may...
Amar Thyagarajan et al.
The Journal of biological chemistry, 279(48), 49680-49688 (2004-09-15)
As axons mature, neurofilament-M (NF-M) expression rises, contributing to maturation of the axonal cytoskeleton and an expansion in axon caliber. This increase is partly due to a rise in NF-M mRNA stability. Such post-transcriptional regulation is often mediated through the...
Manuela Sironi et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20(11), 1910-1912 (2006-08-08)
Deletions within the dystrophin gene (DMD) account for >70% of mutations leading to Duchenne and Becker muscular dystrophies (DMD and BMD). Deletion breakpoints were reported to be scattered within regions that also represent meiotic recombination hot spots. Recent studies indicates...
Ardeshir Hakam et al.
Digestive diseases and sciences, 48(10), 1972-1978 (2003-11-25)
Aberrant c-Src protein kinase activation has been identified as one of the molecular alterations involved in human pancreatic carcinogenesis. It has been postulated that c-Src may induce transformation by causing the overexpression of the insulinlike growth factor-1 receptor (IGF-1R) in...
Eva-Katrin Bentz et al.
Reproductive sciences (Thousand Oaks, Calif.), 14(7), 705-709 (2007-11-15)
The relation between genetic variation of the androgen metabolism and transsexualism is unknown. In a case-control study of 100 male-to-female (MtF) transsexuals, 47 female-to-male (FtM) transsexuals, and 1670 controls, the authors assess allele and genotype frequencies of the steroid 5-alpha...
J Hany et al.
Neurotoxicology and teratology, 21(2), 147-156 (1999-04-07)
The present study has compared the neurobehavioral effects of two structurally different PCB congeners or their combination in rats. Time-mated Long-Evans rats received daily injections of the coplanar PCB 77 (3,4 3',4'-TCB: 0.5 or 1.5 mg/kg), the di-ortho-chlorinated PCB 47...
D E Coulter-Karis et al.
Annals of human genetics, 53(Pt 2), 169-175 (1989-05-01)
Two cDNA clones for human S-adenosylhomocysteine hydrolase isolated from a placental cDNA library were sequenced. Each contained a sequence of 1299 nucleotides encoding a 432 amino-acid protein of MW 47,660. Clone 16-1 contained 47 nucleotides 5' of the coding region...
D L Reimer et al.
DNA and cell biology, 15(4), 317-328 (1996-04-01)
The 3' untranslated region (UTR) of the mouse catalase gene (Cas-1) is demonstrated to be an active site for specific protein interactions. We have identified two regions of the Cas-1 3' UTR mRNA that bind to distinct cytoplasmic proteins: one...
Chen-Zheng Huang et al.
International journal of clinical pharmacology and therapeutics, 50(7), 461-467 (2012-05-15)
Signal transducer and activator of transcription (STAT) 6 signaling pathway is required for mediating the biologic functions of interleukin (IL)-4 which is proved to play an important role in the pathogenesis of allergic diseases and the induction of specific immunoglobulin...
A del Palacio et al.
Mycoses, 42(11-12), 649-655 (2000-02-19)
In a double-blind, randomized study the efficacy and tolerance of flutrimazole 1% cream were compared with ketoconazole 2% cream, applied once daily for 4 weeks, in 60 patients with culturally proven dermatophytosis (47 patients) or cutaneous candidosis (13 patients). Both...
Maria Bai et al.
Human pathology, 38(1), 103-113 (2006-09-05)
The expression of various bcl2 family proteins has been reported in Hodgkin and Reed-Sternberg cells, but the proteins bad, bid, and bim have not been analyzed in classical Hodgkin's lymphomas (HLs). This study aimed to investigate the expression of the...
A Rinken et al.
Neuroreport, 10(3), 493-495 (1999-04-20)
RAT dopamine D2short receptors expressed in CHO cells were characterized by activation of [35S]GTPgammaS binding. There were no significant differences between the maximal effects seen in activation of [35S]GTPgammaS binding caused by dopaminergic agonists, but the effects of 5-HT, 8OH-DPAT...
Harumi Kondo et al.
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 44(3), 161-167 (2003-09-13)
An analytical method was developed for determination of organochlorine, pyrethroid and nitrogen-containing pesticide residues in agricultural products by GC/MS, GC-ECD and GC-FTD. Pesticides were extracted with acetonitrile, and the organic layer was cleaned up on C18 and ENVI-Carb/LC-NH2 cartridges. Pesticides...
Samira S Garboui et al.
Experimental & applied acarology, 40(3-4), 271-277 (2006-11-15)
In the field in south-central Sweden, we tested by randomised, standardised methodology the potential anti-tick repellent activity of two concentrations of MyggA Natural spray (containing PMD) (4.2 and 3.2 g/m2) and one of RB86 (with 70% neem oil containing azadirachtin)...
Xianghua Xu et al.
Brain research. Molecular brain research, 120(2), 205-209 (2004-01-27)
To determine the gene expression level of the lipid-sensitive mechano-gated 2P domain K(+) channels in rat cortex and hippocampus after chronic cerebral ischemia, TREK-1, TREK-2 and TRAAK were detected in rats at 3 and 30 days after permanent bilateral carotid...
Sing-Huang Tan et al.
Oncology reports, 18(5), 1225-1230 (2007-10-05)
The purpose was to validate the use of RUNX3 as a potential biomarker for detection of cancer in serum samples and to determine its sensitivity alone and in combination with p16, RASSF1A and CDH1 using methylation-specific polymerase chain reaction (MSP)....
Monika Mikłaszewska et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 22(3), 377-386 (2013-07-06)
Cardiosurgical operations in cardiopulmonary bypass (CPB) constitute a risk of acute kidney injury (AKI). The aim of the study was an assessment of AKI risk in children within the first 24 hours after CPB cardiac surgery, evaluating serum interleukin 6...
A Okuda et al.
The Journal of biological chemistry, 262(8), 3858-3863 (1987-03-15)
We have isolated the rat placental-type glutathione S-transferase (GST-P) gene from a lambda phage library using GST-P cDNA clone, pGP5 (Sugioka, Y., Kano, T., Okuda, A., Sakai, M., Kitagawa, T., and Muramatsu, M. (1985) Nucleic Acids Res. 13, 6049-6057), as...
Ting-Hai Yang et al.
Dalton transactions (Cambridge, England : 2003), 44(44), 19256-19263 (2015-10-22)
Two novel metal pyridylmethylphosphonates, namely, [Co(4-pmp)] (1) and [Cu(4-pmp)(H2O)] (2), (4-pmpH2 = 4-pyridylmethylphosphonic acid), have been hydrothermally synthesized and characterized by X-ray diffraction, infrared spectroscopy, elemental analysis, and thermogravimetric analysis. In compound 1, each {PO3C} tetrahedron is corner-shared with three...
Chuan-rui Zhang et al.
Natural product communications, 10(8), 1399-1402 (2015-10-06)
Nutmeg, Myristicafragrans, is known for its culinary and medicinal values. The nutmeg pericarp, abundant during the production of the seed, is also used in food and beverage preparations. In this study, the pericarp of M. fragrans was evaluated for its...
Jeremy S Abramson et al.
Leukemia & lymphoma, 54(9), 1915-1920 (2013-01-08)
We conducted a phase 1 trial evaluating the oral nucleoside analog clofarabine in patients with relapsed/refractory non-Hodgkin lymphoma. Patients were treated once daily on days 1 through 21 of a 28-day cycle for a maximum of six cycles. The study...
Jérôme Stirnemann et al.
Orphanet journal of rare diseases, 10, 62-62 (2015-05-15)
In 2009, a worldwide supply constraint of imiglucerase led to treatment modifications or interruptions for patients with Gaucher disease (GD) type 1. In France, joint treatment recommendations were issued to protect the most vulnerable patients. This observational study evaluated the...
Min-Huey Chen et al.
Dental materials : official publication of the Academy of Dental Materials, 22(2), 138-145 (2005-07-26)
The aim of this study was to develop a low shrinkage visible light curable nanocomposite dental restorative material without sacrificing the other properties of conventional materials. This nanocomposite was developed by using an epoxy resin 3,4-epoxycyclohexylmethyl-(3,4-epoxy)cyclohexane carboxylate (ERL4221) matrix with...
He-Li Ding et al.
World journal of gastroenterology, 6(1), 111-114 (2002-01-31)
AIM:To study the relationship of lmp2 and DR3 genes with type I diabetes mellitus.METHODS:lmp2 genotypes and DR3 were identified in 68 patients with type I diabetes mellitus (I -DM) and 71 healthy controls. Then,I -DM patients and controls were respectively...
Jingying Zhang et al.
Journal of agricultural and food chemistry, 68(1), 279-291 (2019-12-06)
This study aimed to identify the key aroma-active volatiles in cranberry wines through three vinification methods (White, Red and Thermo) using GC-MS/O to identify the important aroma compounds. A total of 70 compounds were detected, with 67 in wines and...
R Vormittag et al.
Atherosclerosis, 188(2), 406-411 (2005-12-15)
Data on C-reactive protein (CRP) as a risk indicator of venous thromboembolism are conflicting. A recent study reported higher CRP levels in homozygous carriers of a novel CRP gene polymorphism at the 3' UTR (CRP +1444C>T). We investigated, whether homozygosity...
Cameron C Bright et al.
Physical chemistry chemical physics : PCCP, 19(46), 31072-31084 (2017-11-21)
Small nitrogen containing heteroaromatics are fundamental building blocks for many biological molecules, including the DNA nucleotides. Pyridine, as a prototypical N-heteroaromatic, has been implicated in the chemical evolution of many extraterrestrial environments, including the atmosphere of Titan. This paper reports...
Caroline D van der Marel et al.
European journal of clinical pharmacology, 59(3), 243-251 (2003-05-23)
Data concerning metabolism of paracetamol in infants are scant. Previous studies have examined urinary metabolite recovery rates after a single dose of paracetamol in either neonates (<6 weeks) or children (3-9 years). There are no studies investigating infants. Infants (...
Takehiko Iida et al.
The Journal of organic chemistry, 70(23), 9222-9229 (2005-11-05)
[Reaction: see text]. The synthesis of neuropeptide Y antagonist 1, currently under clinical investigation for the treatment of obesity, is described. The convergent synthesis from trans-spirolactone carboxylic acid intermediate 2a and aminopyrazole 3 is predicated on a stereoselective route to...

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon


Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.