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Microbiology. An enzymatic route to H2 storage.
Inês A C Pereira
Science (New York, N.Y.), 342(6164), 1329-1330 (2013-12-18)
Héctor Torres-Gómez et al.
Bioorganic & medicinal chemistry, 23(15), 4277-4285 (2015-07-07)
Amantadine (1) exerts its anti-Parkinson effects by inhibition of the NMDA associated cation channel and its antiviral activity by inhibition of the M2 protein channel of influenza A viruses. Herein the synthesis, NMDA receptor affinity and anti-influenza activity of analogous
Alessio Innocenti et al.
Bioorganic & medicinal chemistry letters, 15(3), 573-578 (2005-01-25)
A detailed inhibition study of five carbonic anhydrase (CA, EC isozymes with carboxylates including aliphatic (formate, acetate), dicarboxylic (oxalate, malonate), hydroxy/keto acids (l-lactate, l-malate, pyruvate), tricarboxylic (citrate), or aromatic (benzoate, tetrafluorobenzoate) representatives, some of which are important intermediates in
Amani Taamalli et al.
Phytochemical analysis : PCA, 26(5), 320-330 (2015-05-20)
There has been increasing interest dedicated to the phenolic compounds with a view to their antioxidant and healthy properties. Recent studies have focused on plants from the Lamiaceae family with special interest in phenolic compounds antioxidant potential. The metabolite profile
K Schuchmann et al.
Science (New York, N.Y.), 342(6164), 1382-1385 (2013-12-18)
Storage and transportation of hydrogen is a major obstacle for its use as a fuel. An increasingly considered alternative for the direct handling of hydrogen is to use carbon dioxide (CO2) as an intermediate storage material. However, CO2 is thermodynamically
Qian Zhao et al.
Journal of inorganic biochemistry, 149, 39-44 (2015-05-30)
The insulin-mimetic and anti-diabetic properties of vanadium and related compounds have been well documented both in vitro and in vivo. However, the molecular basis of the link between vanadium and the insulin signaling pathway in diabetes mellitus is not fully
Khushbu K Modi et al.
Neurochemical research, 40(11), 2333-2347 (2015-09-25)
Ciliary neurotrophic factor (CNTF) is a promyelinating trophic factor that plays an important role in multiple sclerosis (MS). However, mechanisms by which CNTF expression could be increased in the brain are poorly understood. Recently we have discovered anti-inflammatory and immunomodulatory
Edyta Nalewajko-Sieliwoniuk et al.
Talanta, 133, 38-44 (2014-12-02)
The first method for the simultaneous determination of polyphenolic antioxidants in extracts from leaves of Cirsium palustre based on high performance liquid chromatography combined with flow injection chemiluminescence detection (HPLC-FI-CL) has been developed. The extracts were prepared by using methanol
Mohd Zulkhairi Mohd Yusoff et al.
Biochemical and biophysical research communications, 439(4), 576-579 (2013-09-13)
Pseudogenes are considered to be nonfunctional genes that lack a physiological role. By screening 3985 Escherichia coli mutants using chemochromic membranes, we found four pseudogenes involved in hydrogen metabolism. Knockouts of pseudogenes ydfW and ypdJ had a defective hydrogen phenotype
Grant T Corbett et al.
The Journal of biological chemistry, 288(12), 8299-8312 (2013-02-14)
Neurotrophins, such as brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), are believed to be genuine molecular mediators of neuronal growth and homeostatic synapse activity. However, levels of these neurotrophic factors decrease in different brain regions of patients with Alzheimer disease
Sergey Zakharov et al.
Kidney international, 86(1), 199-207 (2014-03-14)
During an outbreak of methanol poisonings in the Czech Republic in 2012, we were able to study methanol and formate elimination half-lives during intermittent hemodialysis (IHD) and continuous veno-venous hemodialysis/hemodiafiltration (CVVHD/HDF) and the relative impact of dialysate and blood flow
Nicolaas A Verwey et al.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 20(3), 179-187 (2013-07-09)
Abstract Amyloid β-peptide (Aβ) is a key molecule in Alzheimer's disease (AD). Reliable immunohistochemical (IHC) methods to detect Aβ and Aβ-associated factors (AAF) in brain specimens are needed to determine their role in AD pathophysiology. Formic acid (FA) pre-treatment, which
Pavel Kubáň et al.
Analytica chimica acta, 768, 82-89 (2013-03-12)
A simple method using direct injection of human blood samples and quantitative analysis of formate was developed for rapid diagnosis of methanol poisoning. A sample pretreatment device including a 500Da molecular weight cut-off dialysis membrane was in-line coupled to capillary
Therese Fagerqvist et al.
Journal of neurochemistry, 126(1), 131-144 (2013-02-01)
Inclusions of intraneuronal alpha-synuclein (α-synuclein) can be detected in brains of patients with Parkinson's disease and dementia with Lewy bodies. The aggregation of α-synuclein is a central feature of the disease pathogenesis. Among the different α-synuclein species, large oligomers/protofibrils have
Sai Duan et al.
Physical chemistry chemical physics : PCCP, 15(13), 4625-4633 (2013-02-21)
Local structures and adsorption energies of a formic acid molecule and its decomposed intermediates (H, O, OH, CO, HCOO, and COOH) on highly electrocatalytically active mushroom-like Au-core@Pd-shell@Pt-cluster nanoparticles with two atomic layers of the Pd shell and stoichiometric Pt coverage
Michal Holčapek et al.
Analytical and bioanalytical chemistry, 407(17), 5033-5043 (2015-02-20)
A new continuous comprehensive two-dimensional liquid chromatography-electrospray ionization mass spectrometry method has been developed for the lipidomic characterization of complex biological samples. The reversed-phase ultra-high-performance liquid chromatography with a C18 column (150 mm × 1 mm, 1.7 μm) used in the first
Nibedita Kasyapi et al.
Carbohydrate polymers, 92(2), 1116-1123 (2013-02-13)
Bionanowhiskers were extracted from jute by acid hydrolysis. At first cellulose microfibrils were formed by alkali treatment. Addition of an acid to the microfibrils triggered the formation of cellulose nanowhiskers. These were characterized by using different techniques viz. Fourier transform
Lydia Beyer et al.
Journal of bacteriology, 195(7), 1428-1435 (2013-01-22)
Enterobacteria such as Escherichia coli generate formate, lactate, acetate, and succinate as major acidic fermentation products. Accumulation of these products in the cytoplasm would lead to uncoupling of the membrane potential, and therefore they must be either metabolized rapidly or
Bio-inspired catalytic imine reduction by rhodium complexes with tethered Hantzsch pyridinium groups: evidence for direct hydride transfer from dihydropyridine to metal-activated substrate.
Alex McSkimming et al.
Angewandte Chemie (International ed. in English), 52(12), 3411-3416 (2013-02-27)
Lolo Wal Marzan et al.
Archives of microbiology, 195(3), 161-171 (2013-01-01)
Effect of acidic condition on the fermentation characteristics was investigated by the continuous culture of Escherichia coli. In accordance with down-regulation of crp gene transcript level as well as up-regulation of arcA, the expressions of the TCA cycle genes were
J K Htoo et al.
Journal of animal science, 90 Suppl 4, 346-349 (2013-02-13)
Dietary inclusion of salts of organic acids may modulate intestinal microbiota and enhance performance of pigs. Published data on the effects of potassium formate (KF; pH 6.0-8.5) on pig performance are scarce compared with that of potassium diformate (KDF; pH
Jae Young Choi et al.
Biochemical and biophysical research communications, 460(4), 957-963 (2015-04-04)
Inflammatory caspases, such as caspase-1, which is critical for the innate immune response, are activated upon the formation of a molecular complex called the inflammasome. The inflammasome is composed of three proteins, the Nod-like receptor (NLRP, NLRC or AIM2), apoptosis
Petr Kubáň et al.
Journal of chromatography. A, 1281, 142-147 (2013-02-20)
A new method for rapid, direct determination of formate in blood serum samples by capillary electrophoresis with contactless conductometric detection is presented. A selective separation of formate was achieved in approximately 1 min using an electrolyte system comprising 10 mM
Stefano Fogal et al.
Applied microbiology and biotechnology, 99(22), 9541-9554 (2015-06-25)
Formate dehydrogenases (FDHs) are considered particularly useful enzymes in biocatalysis when the regeneration of the cofactor NAD(P)H is required, that is, in chiral synthesis with dehydrogenases. Their utilization is however limited to the recycling of NAD(+), since all (apart one)
Maria G Mason et al.
Biochimica et biophysica acta, 1837(11), 1882-1891 (2014-09-02)
We re-determined the near infrared (NIR) spectral signatures (650-980nm) of the different cytochrome c oxidase redox centres, in the process separating them into their component species. We confirm that the primary contributor to the oxidase NIR spectrum between 700 and
Ting Yang et al.
Water research, 47(3), 1299-1307 (2013-01-02)
Nitrate is often removed from groundwater by ion exchange (IX) before its use as drinking water. Accumulation of nitrate in IX brine reduces the efficiency of IX regeneration and the useful life of the regeneration brine. For the first time
Thomas Berg et al.
Journal of analytical toxicology, 37(3), 159-165 (2013-02-21)
A sensitive ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method has been developed and validated for the quantification of buprenorphine, fentanyl and lysergic acid diethylamide (LSD) in whole blood. Sample preparation was performed by liquid-liquid extraction (LLE) with methyl tert-butyl ether.
Emmanuelle Laffly et al.
FEBS letters, 588(24), 4694-4700 (2014-12-03)
Ficolin-2 has been reported to bind to DNA and heparin, but the mechanism involved has not been thoroughly investigated. X-ray studies of the ficolin-2 fibrinogen-like domain in complex with several new ligands now show that sulfate and phosphate groups are
Peter Stokes et al.
Rapid communications in mass spectrometry : RCM, 28(18), 2024-2030 (2014-08-19)
The atmospheric pressure solids analysis probe (ASAP) has been successfully introduced into laboratories as a routine analytical tool but the technique is labour-intensive and is not easily automated. This paper describes the modifications made to an existing atmospheric pressure gas
Sara Tufi et al.
Journal of chromatography. A, 1395, 79-87 (2015-04-15)
Neurotransmitters are endogenous metabolites that allow the signal transmission across neuronal synapses. Their biological role is crucial for many physiological functions and their levels can be changed by several diseases. Because of their high polarity, hydrophilic interaction liquid chromatography (HILIC)
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