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Saeed Shojaee et al.
Drug development and industrial pharmacy, 40(11), 1451-1458 (2013-08-22)
Polyethylene oxides (PEOs) are extensively used to control the release rate of drugs from matrices. Unfortunately, polyox polymers are prone to oxidation under high temperature and relative humidity. The aim of this study was to investigate the effect of sodium
M P Do et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(2), 342-350 (2014-05-17)
Novel in situ forming implants are presented showing a promising potential to overcome one of the major practical hurdles associated with local periodontitis treatment: limited adhesion to the surrounding tissue, resulting in accidental expulsion of at least parts of the
Zhenhua Yang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(9), 3114-3119 (2012-06-26)
Sodium metabisulfite (SMB) is most commonly used as a food additives, however few study was performed on the vasodilator effect of SMB. In the present paper, the vasodilator effects of SMB and roles of Ca(2+) and K(+) channels as well
Elena Pérez et al.
International journal of pharmaceutics, 470(1-2), 107-119 (2014-05-13)
Environmentally sensitive hydrogels have gained considerable attention in recent years as one of the most promising drug delivery systems. In the present study, two new formulations of pH and temperature stimuli-responsive nanogels (NGs) based on poly-N-isopropylacrylamide (NIPA), N-hydroxyethyl acrylamide (HEAA)
Gisela Palma-Orozco et al.
Phytochemistry, 72(1), 82-88 (2010-11-23)
While a long shelf life for fruit products is highly desired, enzymatic browning is the main cause of quality loss in fruits and is therefore a main problem for the food industry. In this study polyphenol oxidase (PPO), the main
Bidyadhar Mandal et al.
Materials science & engineering. C, Materials for biological applications, 44, 132-143 (2014-10-05)
Interpenetrating network (IPN) type hydrogels of a biopolymer and a synthetic polymer were prepared from chitosan and crosslink copolymer of acrylic acid, sodium acrylate and hydroxyethyl methacrylate. Acrylic acid, sodium acrylate, hydroxyethyl methacrylate and N'N'-methylenebisacrylamide (MBA) monomers were free radically
Jeffrey N Hemenway et al.
Journal of pharmaceutical sciences, 101(9), 3305-3318 (2012-05-23)
A 2,4-dinitrophenylhydrazine (DNPH) precolumn derivatization high-performance liquid chromatography-ultraviolet detection (HPLC-UV) method was developed to quantify levels of formaldehyde and acetaldehyde in polyethylene glycol (PEG) solutions. Formic acid and acetic acid were quantified by HPLC-UV. Samples of neat and aqueous PEG
Ivana Mara da Costa Machado Matos Carvalho et al.
Chemosphere, 82(7), 1056-1061 (2010-11-09)
Sodium metabisulfite is used in marine shrimp harvesting to prevent the occurrence of black spots. Shrimps are soaked in a sodium metabisulfite solution in ice, which is disposed of in sewages that run into marine canals, creating an environmental hazard.
Ceren Kencebay et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 52, 129-136 (2012-11-22)
We aimed at investigating the effects of sulfite-induced lipid peroxidation and apoptosis mediated by secretory phospholipase A2 (sPLA2) on somatosensory evoked potentials (SEP) alterations in rats. Thirty male albino Wistar rats were randomized into three experimental groups as follows; control
Rahul Sonawane et al.
Expert opinion on drug delivery, 11(12), 1833-1847 (2014-08-01)
The primary aim of present work was to develop effective combination drug therapy for topical treatment of psoriasis. Betamethasone dipropionate and calcipotriol loaded solid lipid nanoparticles (CT-BD-SLNs) were prepared by hot melt high shear homogenization technique, which were then incorporated
Melinda A Engevik et al.
American journal of physiology. Gastrointestinal and liver physiology, 308(6), G510-G524 (2015-01-02)
The majority of antibiotic-induced diarrhea is caused by Clostridium difficile (C. difficile). Hospitalizations for C. difficile infection (CDI) have tripled in the last decade, emphasizing the need to better understand how the organism colonizes the intestine and maintain infection. The
Sri Awalia Febriana et al.
Contact dermatitis, 67(5), 277-283 (2012-05-11)
Tannery workers are at considerable risk of developing occupational contact dermatitis. Occupational skin diseases in tannery workers in newly industrialized countries have been reported, but neither the prevalence of occupational allergic contact dermatitis nor the skin-sensitizing agents were specifically examined
Imola Plangár et al.
Ideggyogyaszati szemle, 66(11-12), 407-414 (2014-02-22)
The available scientific data indicate that the pathomechanism of Parkinson's disease (PD) involves the accumulation of endogenous and exogenous toxic substances. The disruption of the proper functioning of certain transporters in the blood-brain barrier and in the blood-cerebrospinal fluid barrier
Wen-Bo Deng et al.
Endocrinology, 155(7), 2704-2717 (2014-05-07)
Thyroid dysfunction during human pregnancy is closely related to serious pregnancy outcome. However, the regulation and function of thyroid hormones during early pregnancy are largely unknown. We found that type II deiodinase, an enzyme converting T4 to activated T3, is
Juan García-Gavín et al.
Contact dermatitis, 67(5), 260-269 (2012-10-09)
Sulfites, preservatives and antioxidants used in the cosmetic, pharmaceutical and food industry are contact allergens whose relevance seems to be difficult to establish. To perform a retrospective study on patients patch tested with a sulfite. Materials and methods. Between 1990
Adriana B Pedale et al.
Anais da Academia Brasileira de Ciencias, 84(4), 1009-1014 (2012-09-20)
The sodium metabisulphite salt is usually used in shrimp culture to prevent black spot. Unfortunately the toxicological effect of this xenobiotic in decapod crabs is unknown. Thus, the present study aims to investigate the sodium metabisulphite LC(50) - 96 h
I U Nieves et al.
Bioresource technology, 102(13), 6959-6965 (2011-05-03)
Microaeration (injecting air into the headspace) improved the fermentation of hemicellulose hydrolysates obtained from the phosphoric acid pretreatment of sugarcane bagasse at 170°C for 10 min. In addition, with 10% slurries of phosphoric acid pretreated bagasse (180°C, 10 min), air
P Abate et al.
Behavioural brain research, 274, 194-204 (2014-08-26)
The endogenous opioid system is involved in ethanol reinforcement. Ethanol-induced changes in opioidergic transmission have been extensively studied in adult organisms. However, the impact of ethanol exposure at low or moderate doses during early ontogeny has been barely explored. We
Immediate type 1 hypersensitivity to apomorphine: a case report.
D Gutiérrez et al.
Journal of investigational allergology & clinical immunology, 21(4), 325-326 (2011-07-05)
Lubica Horvathova et al.
Journal of neuroimmunology, 278, 255-261 (2014-12-04)
The sympathetic nervous system regulates many immune functions and modulates the anti-tumor immune defense response, too. Therefore, we studied the effect of 6-hydroxydopamine induced sympathectomy on selected hematological parameters and inflammatory markers in rats with Yoshida AH130 ascites hepatoma. We
Yan-Fang Tao et al.
Journal of translational medicine, 12, 182-182 (2014-06-26)
Acute myeloid leukemia (AML) is the second most common form of leukemia in children. Aberrant DNA methylation patterns are a characteristic feature in various tumors, including AML. Metallothionein III (MT3) is a tumor suppresser reported to show promoter hypermethylated in
Maria Addolorata Saracino et al.
Journal of pharmaceutical and biomedical analysis, 104, 122-129 (2014-12-17)
A new microextraction by packed sorbent (MEPS) procedure coupled to a high-performance liquid chromatographic method has been developed for quantitation of catecholamines (i.e. norepinephrine, epinephrine and dopamine) in innovative biological samples, namely dried plasma and urine spots. Analyses were carried
Nihal Ozturk et al.
Neurotoxicology and teratology, 33(2), 244-254 (2010-09-30)
The aim of this study was to clarify the dose-dependent effect of sulfite (SO₃²⁻) ingestion on brain and retina by means of electrophysiological and biochemical parameters. Fifty two male Wistar rats, aged 3 months, were randomized into four experimental groups
Wendell Ho-Tin Law et al.
ChemMedChem, 9(6), 1316-1329 (2014-03-20)
We present a new class of phosphorescent cyclometalated iridium(III) bipyridyl-phenylenediamine complexes [Ir(N^C)2 (bpy-DA)](PF6 ) (bpy-DA=4-(N-(2-amino-5-methoxyphenyl)aminomethyl)-4'-methyl-2,2'-bipyridine; HN^C=2-(2,4-difluorophenyl)pyridine (Hdfppy) (1 a), 2-phenylpyridine (Hppy) (2 a), 2-phenylquinoline (Hpq) (3 a), 2-phenylcinchoninic acid methyl ester (Hpqe) (4 a)) and their triazole counterparts [Ir(N^C)2 (bpy-T)](PF6
Sven Dänicke et al.
Mycotoxin research, 28(4), 199-218 (2013-04-23)
Both hydrothermal treatment and wet preservation of mainly deoxynivalenol (DON)-containing, Fusarium toxin (FUS)-contaminated cereal grains with sodium metabisulfite (Na2S2O5 [SBS]) were successfully demonstrated to reduce the DON contamination through formation of the sulfonated derivative of DON, termed as DON sulfonate
S Dänicke et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 27(11), 1558-1565 (2010-08-03)
The Fusarium toxin deoxynivalenol (DON) is of outstanding importance in pig nutrition because of its frequent occurrence in cereal grains at levels high enough to cause adverse effects such as a decrease in feed intake and impairment of the immune
Ping Chu et al.
PLoS pathogens, 10(10), e1004439-e1004439 (2014-10-24)
Francisella tularensis causes the disease tularemia. Human pulmonary exposure to the most virulent form, F. tularensis subsp. tularensis (Ftt), leads to high morbidity and mortality, resulting in this bacterium being classified as a potential biothreat agent. However, a closely-related species
Orlando B S Galli et al.
Bulletin of environmental contamination and toxicology, 89(2), 274-280 (2012-05-31)
Sodium metabisulphite (SMB) is used in marine shrimp aquaculture to prevent the occurrence of black spot. The release SMB into the estuarine environment from shrimp farm pond effluents has been reported. This study evaluated the susceptibility of larvae and post-larvae
Thomas Oliphant et al.
Contact dermatitis, 66(3), 128-130 (2012-02-11)
Sulfites are in widespread use as preservatives/antioxidants. There is increasing recognition of allergic contact dermatitis caused by sodium metabisulfite; however, contact allergy to sodium sulfite is less well recognized. We sought to establish the prevalence of positive patch test reactions
Katsura Hohtatsu et al.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 15(4), 355-359 (2011-09-03)
We conducted a study to evaluate the effect of various anticoagulant agents on large-volume leukocytapheresis using the new Cellsorba CS-180S Filter filled with a changed solution of sodium pyrosulfite and sodium carbonate. We conducted the study on a total of
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