Showing 1-30 of 75 results for "72061"
Tran Thi Nhung et al.
Journal of nanoscience and nanotechnology, 13(8), 5346-5350 (2013-07-26)
Flowerlike gold nanostructure was facilely prepared by the seed-mediated growth of gold nanoparticles in chitosan-TPP template films. Firstly, chitosan nanoparticles, spontaneously formed by inter and/or intra cross-linking with TPP, were transformed into gel-type of chitosan-TPP films under strong sonication process....
Anna Maria Piras et al.
International journal of biological macromolecules, 67, 124-131 (2014-03-26)
A commercially available chitosan (CS) was employed in the formulation of nanoparticles loaded with lysozyme (LZ) as antimicrobial protein drug model. Due to the variability of commercially available batches of chitosans and to the strict dependence of their physical and...
Yasir Ali Arfat et al.
Food chemistry, 141(3), 2848-2857 (2013-07-23)
Impacts of zinc sulphate (ZnSO4) (0-140 μmol/kg) on gel properties of yellow stripe trevally surimi added with sodium tripolyphosphate (STPP) (0.25% and 0.5%, w/w) and protein isolate phosphorylated with STPP at 0.25% and 0.5% (w/w) were studied. Gels from surimi...
Rong-Feng Song et al.
Oncology reports, 32(4), 1481-1488 (2014-07-23)
Gastroenteric cancer is one of the most prevalent cancers and is responsible for most cancer-related deaths worldwide. Paclitaxel (PTX), a classical microtubule inhibitor, is indicated in the treatment of gastric/gastroenteric cancers. In the present study, trimethyl chitosan (TMC)-loaded PTX (TMC-PTX)...
Clarissa R da Cunha et al.
Journal of food science, 77(8), E176-E181 (2012-07-20)
The role of different types of emulsifying salts-sodium citrate (TSC), sodium hexametaphosphate (SHMP), sodium tripolyphosphate (STPP) and tetrasodium pyrophosphate (TSPP)-on microstructure and rheology of "requeijão cremoso" processed cheese was determined. The cheeses manufactured with TSC, TSPP, and STPP behaved like...
Jagatheesh Kaliaperumal et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 68(6), 763-773 (2014-09-02)
At present, the majority of established treatments for breast cancer are based on clinical manifestations, some fundamental of molecular and cellular biology of cancer. In recent times, the therapy is moving towards personalized medicines. Nevertheless, both the methodologies have own...
Emmanuel N Koukaras et al.
Molecular pharmaceutics, 9(10), 2856-2862 (2012-08-01)
This work reports details pertaining to the formation of chitosan nanoparticles that we prepare by the ionic gelation method. The molecular interactions of the ionic cross-linking of chitosan with tripolyphosphate have been investigated and elucidated by means of all-electron density...
Lucien Bettendorff et al.
The FEBS journal, 280(24), 6443-6455 (2013-09-12)
The CYTH superfamily of proteins was named after its two founding members, the CyaB adenylyl cyclase from Aeromonas hydrophila, and the human 25-kDa thiamine triphosphatase (ThTPase). Members of this superfamily of proteins exist in all organisms, including bacteria, archaeons, fungi, plants...
Akile Çelik et al.
International journal of biological macromolecules, 89, 406-414 (2016-05-08)
β-Glucosidase was covalently immobilized on chitosan-MWCNTs carrier and its aroma enhancement effect in different tea samples was investigated. Chitosan-MWCNTs carrier was prepared by mixing chitosan with MWCNTs (5:1w/w) and characterization of prepared composite carrier was done by FTIR, TGA and...
Apoorv Gupta et al.
Biotechnology and bioengineering, 110(2), 552-562 (2012-08-21)
We demonstrate that "nanofactory"-loaded biopolymer capsules placed in the midst of a bacterial population can direct bacterial communication. Quorum sensing (QS) is a process by which bacteria communicate through small-molecules, such as autoinducer-2 (AI-2), leading to collective behaviors such as...
Hitesh Jagani et al.
Cellular & molecular biology letters, 18(1), 120-136 (2012-12-29)
Overexpression of anti-apoptotic Bcl-2 is often observed in a wide variety of human cancers. It prevents the induction of apoptosis in neoplastic cells and contributes to resistance to chemotherapy. RNA interference has emerged as an efficient and selective technique for...
K Konecsni et al.
Food chemistry, 134(4), 1775-1779 (2013-02-28)
Chitosan (CH)-tripolyphosphate (TPP) submicron particles were formed as carriers of entrapped rutin, and the release properties characterized using simulated gastric juices and fluids of the small intestine. Particle size, charge and entrapment efficiencies were investigated as a function of the...
Wei Liu et al.
Journal of food science, 80(11), C2413-C2419 (2015-09-30)
The dynamic hydrolysis of tetrasodium pyrophosphate (TSPP), sodium tripolyphosphate (STPP) and polyphosphate compound, which was catalyzed by purified pyrophosphatase (PPase) and myosin- tripolyphosphatase (TPPase) from the silver carp dorsal muscle, was studied using (31) P NMR spectroscopy. In the PPase...
Yuancai Dong et al.
Carbohydrate polymers, 94(2), 940-945 (2013-04-03)
The purpose of this study is to synthesize chitosan (CS) nanoparticles (NPs) by ionic gelation with tripolyphosphate (TPP) as crossslinker in static mixers. The proposed static mixing technique showed good control over the ionic gelation process and 152-376 nm CS...
L Chen et al.
Journal of dairy science, 95(9), 4823-4830 (2012-08-25)
The aim of this study was to investigate the effect of different types and concentrations of emulsifying salts (trisodium citrate, tetrasodium pyrophosphate, sodium tripolyphosphate, sodium hexametaphosphate, and disodium orthophosphate) on the physicochemical properties of processed cheese. The physicochemical composition, texture...
Ruchira N Wijesena et al.
Carbohydrate polymers, 134, 182-189 (2015-10-03)
A method of coloration of cotton fabrics with nano chitosan is proposed. Nano chitosan were prepared using crab shell chitin nanofibers through alkaline deacetylation process. Average nano fiber diameters of nano chitosan were 18 nm to 35 nm and the...
Venkata P Mantripragada et al.
Journal of biomedical materials research. Part A, 102(12), 4276-4289 (2014-02-06)
This study investigates the influence of the controlled release of bone morphogenetic protein 7 (BMP-7) from cross-linked chitosan microparticles on pre-osteoblasts (OB-6) in vitro. BMP-7 was incorporated into microparticles by encapsulation during the particle preparation and coating after particle preparation....
Yuzhi Deng et al.
Carbohydrate polymers, 111, 864-869 (2014-07-20)
An insoluble biocomposite composed of potato starch and chitosan was prepared by microwave treatment. The effect of pH on swelling (liquid absorption) behavior of the composites was investigated at pH 2, pH 6.8 and pH 12. Analysis revealed that the...
Siddhesh S Kamat et al.
Biochemistry, 52(42), 7366-7368 (2013-10-12)
The C-P lyase complex in bacteria catalyzes the transformation of phosphonates to orthophosphate under conditions of phosphate starvation. The first committed step in the C-P lyase-catalyzed reaction is the displacement of adenine from MgATP by phosphonate substrates, yielding ribose-1-phosphonate-5-triphosphate. In...
K Saagar Vijayaragavan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 967, 118-126 (2014-08-03)
Vaccine production faces a challenge in adopting conventional downstream processing steps that can efficiently purify large viral particles. Some major issues that plague vaccine purification are purity, potency, and quality. The industry currently considers 30% as an acceptable virus recovery...
Yohan Yoon et al.
Meat science, 95(2), 317-322 (2013-06-12)
This study evaluated chemical tenderizers and cooking methods to inactivate Escherichia coli O157:H7 in ground beef patties (model system for non-intact beef). Ground beef was inoculated with E. coli O157:H7 and mixed with (i) nothing (control), (ii) calcium chloride (CC)...
Jessica L Adams et al.
Journal of acquired immune deficiency syndromes (1999), 62(3), 260-266 (2012-11-01)
The active metabolites of tenofovir (TFV) and emtricitabine (FTC) in peripheral blood mononuclear cells (PBMCs) have been used as markers of long-term antiretroviral (ARV) adherence. However, the process of isolating PBMCs is expensive, complex, and not feasible in many settings....
Rajpal Srivastav et al.
Nucleic acids research, 42(12), 7894-7910 (2014-06-01)
DHH superfamily includes RecJ, nanoRNases (NrnA), cyclic nucleotide phosphodiesterases and pyrophosphatases. In this study, we have carried out in vitro and in vivo investigations on the bifunctional NrnA-homolog from Mycobacterium smegmatis, MSMEG_2630. The crystal structure of MSMEG_2630 was determined to...
Gozde Unsoy et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 62, 243-250 (2014-06-17)
Targeted drug delivery is a promising alternative to overcome the limitations of classical chemotherapy. In an ideal targeted drug delivery system carrier nanoparticles would be directed to the tumor tissue and selectively release therapeutic molecules. As a novel approach, chitosan...
Siva Ram Kiran Vaka et al.
Journal of drug targeting, 21(1), 44-53 (2012-10-02)
To develop formulations of carnosic acid nanoparticles and to assess their in vivo efficacy to enhance the expression of neurotrophins in rat model. Carnosic acid loaded chitosan nanoparticles were prepared by ionotropic gelation technique using central composite design. Response surface...
Hongyan Wang et al.
The AAPS journal, 15(1), 242-249 (2012-11-28)
Decitabine (DAC) is used for treatment of patients with myelodysplastic syndromes and acute myeloid leukemia (AML). Following cellular uptake, DAC is activated to DAC-triphosphate (TP) and incorporated into DNA. Once incorporated into the DNA, DAC-TP binds and inactivates DNA methyltransferases...
Meenakshi Malhotra et al.
International journal of nanomedicine, 8, 2041-2052 (2013-06-01)
Recently, cell-penetrating peptides have been proposed to translocate antibodies, proteins, and other molecules in targeted drug delivery. The proposed study presents the synthesis and characterization of a peptide-based chitosan nanoparticle for small interfering RNA (siRNA) delivery, in-vitro. Specifically, the synthesis...
Jake T Neumann et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(1), 121-130 (2014-11-06)
Ischemic preconditioning (IPC) via protein kinase C epsilon (PKCɛ) activation induces neuroprotection against lethal ischemia. Brain-derived neurotrophic factor (BDNF) is a pro-survival signaling molecule that modulates synaptic plasticity and neurogenesis. Interestingly, BDNF mRNA expression increases after IPC. In this study...
Su Zhang et al.
Current protocols in nucleic acid chemistry, Chapter 4, Unit 4-Unit 4 (2013-03-21)
This unit describes the chemical synthesis of α-L-threofuranosyl nucleic acid (TNA) triphosphates for thymidine (T), guanosine (G), cytidine (C), and the diaminopurine (D) analog of adenosine and their incorporation into TNA oligonucleotides by enzyme-mediated polymerization of a DNA primer-template complex....
Si Eun Baek et al.
Biochemical and biophysical research communications, 456(2), 591-597 (2014-12-10)
Duplex RNA harboring the 5'-terminal triphosphate RNA is hypothesized to not only execute selective gene silencing via RNA interference, but also induce type I interferon (IFN) through activation of the retinoic acid inducible gene I (RIG-I). We evaluated gene silencing...

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