Search Within
73677
Keyword:'73677'
Showing 1-30 of 45 results for "73677" within Papers
Nephron. Physiology, 95(2), p28-p35 (2003-11-12)
Biliary obstruction affects the renal response to ischemia and also elicits a hepatic cytokine response. Using a murine model, we now test the hypothesis that these hepatic cytokines help determine the outcome of ischemic acute renal failure. C3H/HEN mice were
Effect of tobacco smoking on albumin concentration and beta-glucuronidase activity in urine of smelters
Przegla?d Lekarski, 71(11), 581-584 (2014)
Synthesis of Glycaro-1, 5-lactams and Tetrahydrotetrazolopyridine-5-carboxylates: Inhibitors of beta-D-Glucuronidase and alpha-L-Iduronidase
Helvetica Chimica Acta, 89(4), 635-666 (2006)
Chemistry & biodiversity, 11(7), 1078-1087 (2014-07-22)
Three chromone analogs, 1-3, a chlorinated alkaloid sclerotioramine (4), together with two 11-noreremophilane-type sesquiterpenes with a conjugated enolic OH group and a brominated one, 5 and 6, respectively, were isolated from Penicillium citreonigrum (HQ738282). Compounds 1, 5, and 6 were
Indian journal of experimental biology, 52(10), 965-971 (2014-10-28)
In vitro study revealed that pancreatic lipase inhibitory activity of C. asiatica extract was significantly higher than rutin but lower than orlistat, an anti-obesity drug. alpha-Amylase inhibitory activities of C. asiatica extract and rutin were significantly lower than acarbose, an
Bollettino dell'Istituto sieroterapico milanese, 60(1), 26-30 (1981-01-01)
Beta-glucuronidase activity has been investigated in 1,221 Enterobacteriaceae strains. The test, using p-nitrophenyl-beta-D-glucuronide (pNPGlcU) agar culture, can be included easily in the routine Enterobacteriaceae biochemical assays. The test is discriminating for Enterobacteriaceae genera and species and useful for identification of
Acta biochimica et biophysica Hungarica, 25(1-2), 87-92 (1990-01-01)
Several reactions of the Ist and IInd phase of biotransformation have been reported to be under a negative cyclic-AMP dependent control. Conjugation of bilirubin and glucuronidation of morphine were investigated in isolated mouse hepatocytes and in mouse hepatocyte microsomes, respectively.
Rapid separation of p-nitrophenol and its glucuronide and sulfate conjugates by reversed-phase high-performance liquid chromatography.
Journal of chromatography, 177(2), 368-371 (1979-09-21)
beta-Glucuronidase Inhibitory Effect of Phenolic Constituents from Phyllanthus amarus.
Pharmaceutical biology, 45(5), 363-365 (2007)
FEBS letters, 463(3), 345-349 (1999-12-22)
The role of aromatic hydrocarbon receptor (AhR)-mediated signal transduction pathways was investigated in the regulation of ascorbate synthesis by using Ah-responsive and Ah-unresponsive mouse strains. In vivo 3-methylcholanthrene treatment increased hepatic and plasma ascorbate concentrations only in the Ah-responsive strain.
Molecular microbiology, 74(3), 541-556 (2009-08-07)
Clostridium difficile is a nosocomial pathogen that can cause severe gastrointestinal infections. C. difficile encodes a family of cell wall proteins, some of which are implicated in pathogenesis. Here we have characterized CwpV, the largest member of this family. CwpV
Drug metabolism and disposition: the biological fate of chemicals, 9(1), 15-18 (1981-01-01)
Cytochrome P-450, NADPH-cytochrome P-450 reductase, and glucuronyltransferase were immobilized simultaneously on cyanogen bromide-activated Sepharose from phenobarbital-induced rabbit liver microsomes. The activity of the P-450 system was demonstrated by the N-demethylation of ethylmorphine and the O-demethylation of p-nitroanisole. p-Nitrophenol produced from
Journal of chromatography, 532(2), 285-293 (1990-11-16)
p-Nitrophenol (pNP) and its conjugated metabolites, generated in a perfused rat liver preparation, are readily separated and quantitated in serum perfusate and bile samples using a reverse-phase high-performance liquid chromatographic method. Serum perfusate samples can be analyzed following protein precipitation
The Journal of pharmacology and experimental therapeutics, 227(3), 658-662 (1983-12-01)
Female Fischer 344 rats administered p-nitrophenol (0.05 mmol/kg) excrete more p-nitrophenylglucuronide in the urine than males (35.9 +/- 2.9 vs. 14.1 +/- 4.0% of total urinary metabolites, respectively). In contrast, hepatic microsomes prepared from male rats have higher UDP-glucuronyltransferase activity
Gas chromatographic-mass spectrometric analysis for measurement of p-cresol and its conjugated metabolites in uremic and normal serum.
Clinical chemistry, 51(8), 1535-1538 (2005-07-26)
Positive and negative liquid secondary ion mass spectrometry of chloro- and nitrophenylglucuronides.
Biomedical mass spectrometry, 12(3), 127-133 (1985-03-01)
Mass spectra of a series of chloro- and nitrophenylglucuronides by liquid secondary ion (LSI) mass spectrometry were obtained. In the positive ion mode class characteristic fragmentations and adduct ions are observed only in the presence of alkali salt additives. No
Anti-cancer agents in medicinal chemistry, 15(3), 285-290 (2014-10-30)
PreQ0 base (7-cyano-7-deazaguanine, compound 1) is the biosynthetic precursor of queuosine-tRNA and important synthetic intermediate for bioactive compounds. It was obtained for the first time as a new natural product from a mangrove actinomycete Streptomyces qinglanensis 172205, during the course
Biochimica et biophysica acta, 1379(1), 1-6 (1998-02-19)
Intestinal absorption of beta-disaccharide (cellobiose, maltose and lactose) conjugates of p-nitrophenol (p-nitrophenyl beta-disaccharide) were examined in terms of the hydrolysis of disaccharide conjugate to monosaccharide conjugate and the transport of monosaccharide conjugate by Na+/glucose transport carrier (SGLT1). beta-Cellobioside, beta-maltoside and
Journal of chromatography, 414(1), 139-148 (1987-02-20)
Molecular-secondary-ion mass spectrometry (SIMS) is a suitable method for the analysis of nonvolatile substances such as conjugated metabolites of drugs. We have developed a simple method for the direct SIMS measurement of conjugates following thin-layer chromatography without any extraction procedure.
Determination of tissue UDP-glucuronic acid levels by high-pressure liquid chromatography.
Analytical biochemistry, 127(1), 68-72 (1982-11-15)
Journal of ethnopharmacology, 164, 210-222 (2015-02-24)
Jinqi Jiangtang Tablet is a traditional Chinese anti-diabetic formula containing three ingredients: Coptis chinensis Franch. (dried rhizome of C. chinensis Franch., Coptis deltoidea C. Y. Cheng et Hsiao and Coptis teeta Wall.), Astragalus membranaceus (Fisch.) Bunge. (dried root of A.
Purification and properties of beta-glucuronidase from human placenta.
Biochemistry, 17(3), 385-391 (1978-02-07)
Phytochemistry, 106, 197-206 (2014-07-24)
Eight pregnane-type steroidal glycosides substituted with ortho-acetate groups were isolated from the methanolic extract of the pericarp of Gymnema griffithii fruits, and named gymnemogriffithosides A-H. Their structures were determined by spectroscopic analysis (one and two dimensional nuclear magnetic resonance, high
Toxicology, 36(2-3), 159-169 (1985-08-01)
Single-pass perfusion in situ of mouse livers with the organophosphate paraoxon resulted in formation of p-nitrophenol (PNP), p-nitrophenyl sulfate (PNPS), and p-nitrophenyl-beta-D-glucuronide (PNPG). Following initiation of perfusion of paraoxon steady--state conditions were achieved in 15-25 min, at which time the
PLoS neglected tropical diseases, 8(8), e3111-e3111 (2014-08-29)
Paracoccidioides brasiliensis and P. lutzii cause paracoccidioidomycosis (PCM). P. brasiliensis main diagnostic antigen is glycoprotein gp43, and its peptide sequence is 81% identical with a P. lutzii ortholog here called Plp43. P. lutzii ("Pb01-like") apparently predominates in Midwestern/Northern Brazil, where
The Journal of pharmacology and experimental therapeutics, 295(2), 830-835 (2000-10-25)
Congestive heart failure has been shown to affect oxidative drug metabolism, however, there has been little study of its effects on drug conjugation. Using the isolated perfused livers from rats with right ventricular failure (RVF) due to pulmonary artery constriction
FEBS letters, 588(17), 3213-3217 (2014-07-16)
The role of calcium ion in the active site of the inverting glycoside hydrolase family 97 enzyme, BtGH97a, was investigated through structural and kinetic studies. The calcium ion was likely directly involved in the catalytic reaction. The pH dependence of
[Quantification of p-nitrophenolglucuronide and sulfate in blood and urine using enzyme hydrolysis and HPLC following E 605-poisoning].
Beitrage zur gerichtlichen Medizin, 41, 103-107 (1983-01-01)
The Journal of biological chemistry, 259(12), 7705-7711 (1984-06-25)
Rates of production of p-nitrophenyl glucuronide by isolated perfused livers from fed or fasted phenobarbital-treated rats were estimated by monitoring the concentration of glucuronide in the effluent perfusate. Infusion of epinephrine decreased the steady state level of p-nitrophenyl glucuronide by
Effect of dietary honey on intestinal microflora and toxicity of mycotoxins in mice
BMC Complementary and Alternative Medicine, 6(1), 6-6 (2006)
Page 1 of 2