Showing 1-30 of 113 results for "740063"
Lili Zhang et al.
Journal of chromatography. A, 1365, 86-93 (2014-09-30)
Fourteen chitosan 3,6-diphenylcarbamate-2-urea derivatives were synthesized using well-deacetylated chitosan and the corresponding phenyl isocyanates. After coating them on silica gel, their chiral recognition abilities were evaluated as the chiral stationary phases (CSPs) for high-performance liquid chromatography. These coated-type CSPs exhibited...
S Dheeranupattana et al.
Pakistan journal of biological sciences : PJBS, 16(18), 950-954 (2014-02-08)
The study purposed to investigate the protein expression of Stemona alkaloids biosynthesis response to chitosan elicitor by 2D gel electrophoresis. The total proteins extraction of Stemona roots were performed for comparison with the control and chitosan treatments. It was found...
Tomas Lafarga et al.
Journal of agricultural and food chemistry, 61(37), 8790-8796 (2013-08-22)
Chitosan is nature's second most abundant polymer after cellulose and forms the structural support in crustacean shell material and Basidomycete mushroom stalks. Chitosan is a known antimicrobial agent but, to date, was not examined as an antimicrobial agent in bread...
Pallab Datta et al.
Journal of biomedical nanotechnology, 9(5), 870-879 (2013-06-28)
Most polymeric nanofibers used for bone tissue engineering lack adequate functional groups for bioactivity. This study explores the potential of nanofibers of phosphate functionalized derivative of chitosan-N-methylene phosphonic chitosan (NMPC) for bone tissue engineering. Nanofibers were fabricated by electrospinning of...
Changyun Qian et al.
Carbohydrate polymers, 97(2), 676-683 (2013-08-06)
In this study, N-phosphonium chitosans (NPCSs) with two degrees of substitution were synthesized in a homogeneous system as nonviral gene vectors. Grafted polymer/DNA complexes at various charge ratios were formulated and characterized. Particle sizes of NPCS/DNA complexes were between 110...
Sara Gnavi et al.
International review of neurobiology, 109, 1-62 (2013-10-08)
Various biomaterials have been proposed to build up scaffolds for promoting neural repair. Among them, chitosan, a derivative of chitin, has been raising more and more interest among basic and clinical scientists. A number of studies with neuronal and glial...
Shouan Zhu et al.
Annals of the rheumatic diseases, 74(1), 285-293 (2013-11-22)
Osteoarthritis (OA) is a degenerative joint disease characterised by cartilage degradation and chondrocyte hypertrophy. A recent study showed that Rac1 promoted expression of MMP13 and chondrocyte hypertrophy within the growth plate. These findings warrant further investigations on the roles of...
Shuping Wu et al.
Food chemistry, 148, 196-203 (2013-11-23)
The structure, UV absorbance, browning intensity, fluorescence changes, antioxidant activity and antimicrobial assessment of Maillard reaction products (MRPs) derived from xylan with chitosan, chitooligomer, glucosamine hydrochloride and taurine model systems were evaluated. The results revealed that all MRPs had similar...
K T Shalumon et al.
Journal of biomedical nanotechnology, 9(3), 430-440 (2013-04-30)
A biomimetic scaffold which can very closely mimic the extracellular matrix of the bone was fabricated by incorporating nano-bioceramic particles such as nano bioglass (nBG) and nano hydroxyapatite (nHAp) within electrospun nanofibrous scaffold. A comparative study between nHAp incorporated poly(caprolactone)...
Mariela Agotegaray et al.
Journal of nanoscience and nanotechnology, 14(5), 3343-3347 (2014-04-17)
New magnetic devices consisting of magnetite functionalized with oleic acid and chitosan have been synthesized and employed to the loading of Diclofenac as potential tool for treatment of targeted inflammatory diseases. Magnetic loaded and un-loaded nanoparticles have been thoroughly characterized...
Prabhu Prabhakara et al.
Pakistan journal of pharmaceutical sciences, 26(4), 779-786 (2013-07-03)
Site-specific delivery of anticancer based therapy of human cancers has led to several remarkable outcomes, particularly in the therapy of breast cancer and lymphoma. Camptothecin, a plant secondary metabolite is widely used in the treatment of metastatic breast cancer and...
Shoko Shinya et al.
The Journal of biological chemistry, 288(42), 30042-30053 (2013-08-30)
Two carbohydrate binding modules (DD1 and DD2) belonging to CBM32 are located at the C terminus of a chitosanase from Paenibacillus sp. IK-5. We produced three proteins, DD1, DD2, and tandem DD1/DD2 (DD1+DD2), and characterized their binding ability. Transition temperature...
Rong Huang et al.
Journal of biomedical nanotechnology, 10(7), 1346-1358 (2014-05-09)
Catalase, a kind of redox enzyme and generally recognized as an efficient agent for protecting cells against hydrogen peroxide (H2O2)-induced cytotoxicity. The immobilization of catalase was accomplished by depositing the positively charged chitosan and the negatively charged catalase on electrospun...
Osama A A Ahmed et al.
Expert opinion on drug delivery, 11(7), 1005-1013 (2014-04-08)
To optimize and use of glimepiride (GMD)-loaded self-nanoemulsifying delivery systems (SNEDs) for the preparation of transdermal patches. Mixture design was utilized to optimize GMD-loaded SNEDs in acidic and aqueous pH media. Optimized GMD-loaded SNEDs were used in the preparation of...
Qianqian Lyu et al.
The Biochemical journal, 461(2), 335-345 (2014-04-29)
Chitosanase is able to specifically cleave β-1,4-glycosidic bond linkages in chitosan to produce a chito-oligomer product, which has found a variety of applications in many areas, including functional food and cancer therapy. Although several structures for chitosanase have been determined...
Sandra Elisa Haas et al.
Pharmaceutical development and technology, 19(7), 769-778 (2013-09-04)
The aim of this study was to develop innovative nanosystems with isopropyl myristate as the oil core of self-assembly nanovesicles constituted of chitosan and lecithin using a 2(3) factorial design. The factors analyzed were chitosan (X1, levels 4 and 8...
R Shelma et al.
Journal of biomedical nanotechnology, 9(2), 167-176 (2013-05-01)
The overall goal of this paper was to enhance the bioavailability of orally delivered insulin. A mucoadhesive amphiphilic chitosan derivative, lauroyl sulphated chitosan (LSCS) was used as the oral carrier for insulin. Trans epithelial electrical resistance experiment was performed on...
Hongyu Yang et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 68(1), 209-216 (2013-07-05)
Ethylenediaminetetraacetic dianhydride (EDTAD)-modified magnetic-Fe3O4 chitosan (EMC), prepared using the cross-link agent glutaraldehyde and chemicals Fe3O4, chitosan, and EDTAD, was used to compare the adsorption of methylene blue (MB) with magnetic chitosan (MC). The composite structure was confirmed by multiple characterization...
Pranee Lertsutthiwong et al.
Journal of environmental sciences (China), 25(2), 262-267 (2013-04-20)
The effects of chitosan characteristics including the degree of deacetylation, molecular weight, particle size, pH pretreatment and immobilization time on the immobilization of nitrite-oxidizing bacteria (NOB) on biopolymeric chitosan were investigated. Nitrite removal efficiency of immobilized NOB depended on the...
A L Kavitha et al.
Journal of nanoscience and nanotechnology, 13(1), 98-104 (2013-05-08)
This work was aimed to develop reusable magnetite chitosan composite containing carbon paste electrode for biosensor application. Glucose oxidase (GOx) enzyme was used to prepare GOx-magnetite-chitosan nanocomposite containing carbon paste electrode for sensitive detection of glucose. The immobilized enzyme retained...
Abdelkrim El Kadib et al.
Journal of nanoscience and nanotechnology, 14(1), 308-331 (2014-04-16)
Polysaccharides are a new class of pervasive biopolymers that display many advantages including wide availability, sustainability, inherent inclusion of chemical functionality, biocompatibility and biodegradability. Current efforts are focused on the catalytic transformation of these macromolecules into fuels and platform chemicals....
Gurpreet Kaur Khaira et al.
Journal of water and health, 11(3), 410-418 (2013-08-29)
The antibacterial activity of a water-soluble chitosan derivative prepared by chemical modification to quaternary ammonium compound N,N,N-trimethylchitosan (TC) was investigated against four selected waterborne pathogens: Aeromonas hydrophila ATCC 35654, Yersinia enterocolitica ATCC 9610, Listeria monocytogenes ATCC 19111 and Escherichia coli...
I-Mo Fang et al.
Experimental eye research, 130, 38-50 (2014-12-06)
The purpose of the present study was to investigate the protective effect and mechanism of chitosan oligonucleotides (COS) on retinal ischemia and reperfusion (I/R) injury. Rats pretreated with PBS, low-dose COS (5 mg/kg), or high-dose COS (10 mg/kg) were subjected to retinal...
Dae-Sung Lee et al.
Food chemistry, 148, 97-104 (2013-11-23)
In this study, the antioxidant and antimicrobial activities of chitosan-caffeic acid, chitosan-ferulic acid, and chitosan-sinapic acid conjugates with different grafting ratios were investigated. The synthesized chitosan-hydroxycinnamic acid conjugates were verified by performing (1)H NMR and differential scanning calorimetry analysis. The...
J Pradeep Kumar et al.
Journal of biomedical nanotechnology, 10(6), 970-981 (2014-04-23)
The scaffolds for bone tissue engineering should be porous to harbor the growth of new tissue ingrowths, biodegradable with no toxic end products, and biocompatible with no cytotoxicity. In this study we report that Diopside (CaMgSi2O6) (Dp) particles can be...
Lee A Hadwiger
Plant science : an international journal of experimental plant biology, 208, 42-49 (2013-05-21)
Chitosan, a naturally occurring polymer, became available in the 1980s in industrial quantities enabling it to be tested as an agricultural chemical. A usual procedure for developing agricultural chemicals starts by testing a number of different chemically synthesized molecules on...
Bo Xiao et al.
Gastroenterology, 146(5), 1289-1300 (2014-02-08)
Nanoparticles have been explored as carriers of small interfering RNAs (siRNAs) and might be developed to treat patients with inflammatory bowel disease (IBD). Overexpression of CD98 on the surface of colonic epithelial cells and macrophages promotes the development and progression...
A Shakila Banu et al.
IET nanobiotechnology, 7(1), 22-27 (2013-05-28)
Nanoenabled drug carriers are emerging as alternatives to conventional small-molecule drugs and their in-vitro biocompatibility evaluation with blood components is a necessary part of early preclinical development. In the present study, Chitosan-based bionanocomposites of sol-gel derived TiO2 and SiO2 were...
Chitosan-based Biomaterials."Innovative Polymers Engineered for Drug Delivery and Tissue Engineering
Wu G, et al.
Material Matters, 7(3) null
Liming Hu et al.
Nanoscale, 5(8), 3103-3111 (2013-03-22)
Within the past few years, chitosan-based drug delivery vehicles have become some of the most attractive to be studied. In contrast to all other polysaccharides, chitosan has demonstrated its unique characteristics for drug delivery platforms, including its active primary amino...

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