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K Kubota et al.
Journal of pharmaceutical sciences, 82(10), 1039-1045 (1993-10-01)
The percutaneous permeation and sorption isotherm (equilibrium) profiles of betamethasone and betamethasone 17-valerate were estimated in an in vitro study with excised human skin. Corticosteroids were measured by HPLC. The stratum corneum (dry weight)/water partition coefficient of betamethasone 17-valerate was
YanQiu Nie et al.
Bioresource technology, 99(8), 2989-2995 (2007-08-08)
Gas circulation and fed-batch fermentation were applied for enhancing acetate production by mixed culture in a novel syntrophic acetogenesis and homoacetogenesis coupling system. The results show that the acetate yield in the fed-batch test with gas circulation is about 47%
Salka Keller et al.
Journal of controlled release : official journal of the Controlled Release Society, 191, 24-33 (2014-04-05)
Synthetic subunit vaccines need to induce CD8(+) cytotoxic T cell (CTL) responses for effective vaccination against intracellular pathogens. Most subunit vaccines primarily generate humoral immune responses, with a weaker than desired CD8(+) cytotoxic T cell response. Here, a neutral, pH-responsive
Ling-Hsien Tu et al.
ACS chemical biology, 9(7), 1632-1637 (2014-05-20)
The loss of β-cell function and β-cell death are key features of diabetes. A range of mechanisms are thought to contribute to β-cell loss, including islet amyloid formation by the neuropancreatic hormone amylin (islet amyloid polypeptide, IAPP). Islet amyloid deposition
Chemistry. Connecting biomass and petroleum processing with a chemical bridge.
Joseph J Bozell
Science (New York, N.Y.), 329(5991), 522-523 (2010-07-31)
Hadas Lapid et al.
Journal of neurophysiology, 102(4), 2121-2130 (2009-08-07)
Electroolfactograms (EOGs) are the summated generator potentials of olfactory receptor neurons measured directly from the olfactory epithelium. To validate the sensory origin of the human EOG, we set out to ask whether EOGs measured in humans were odorant concentration dependent.
Maria Luisa Vuotto et al.
The Journal of pharmacy and pharmacology, 55(3), 399-405 (2003-05-02)
Catechins and their derivatives are abundant flavanols in the plant kingdom. Usually, catechin activity correlates with chemical structure. We hypothesized that by adding hydrophobic groups to the native catechin, we could ameliorate penetration of the cell and make the derivatives
M F Böttcher et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 30(11), 1590-1596 (2000-11-09)
The prevalence of allergic diseases has increased particularly over the past 30-40 years. A reduced microbial stimulation during infancy may result in a development of a disturbed balance between Th1- and Th2-like immunity. The gut flora is, quantitatively, the most
Koichi Tomoda et al.
The Journal of toxicological sciences, 36(3), 261-266 (2011-06-02)
Cigarette smoke has been known to affect the development of bowel disease. However it has not been fully elucidated how cigarette smoke has effects on the gut. In this context we evaluated not only caecal levels of organic acids but
Henry Bernard et al.
The Journal of infectious diseases, 211(1), 156-165 (2014-08-21)
A predominantly T-helper type 2 (Th2) immune response is critical in the prognosis of pulmonary Pseudomonas aeruginosa infection. But the mucosal and systemic immune responses can be influenced by the intestinal microbiota. We assessed the effect of microbiota compositional changes
Tsugunobu Andoh et al.
Pharmacological reports : PR, 66(4), 699-703 (2014-06-21)
Proteinase-activated receptor-2 (PAR2) is involved in dermatophyte-induced scratching and leukotriene B4 (LTB4) release from keratinocytes. We investigated whether PAR2-mediated LTB4 production is involved in dermatophyte-induced scratching. Dermatophyte extract was injected intradermally and scratching was observed in mice. LTB4 was determined
Tripti Raghavendra et al.
BioMed research international, 2014, 353845-353845 (2014-08-06)
Pentyl valerate was synthesized biocatalytically using Candida rugosa lipase (CRL) immobilized in microemulsion based organogels (MBGs). The optimum conditions were found to be pH 7.0, temperature of 37 °C, ratio of concentration of water to surfactant (Wo) of 60, and
Pentenoic acid pathways for cellulosic biofuels.
Regina Palkovits
Angewandte Chemie (International ed. in English), 49(26), 4336-4338 (2010-05-19)
Satoko Sudo et al.
Pain, 98(3), 277-286 (2002-07-20)
In human studies, repeated intraoral application of strong acidic or salt stimuli induces irritation that progressively increases across trials (sensitization), whereas irritation elicited by nicotine progressively decreases (desensitization). We investigated whether nociceptive neurons in trigeminal subnucleus caudalis (Vc) exhibit increasing
Kumar G Janoria et al.
Current eye research, 31(10), 797-809 (2006-10-14)
The objective of this research was to investigate the presence of sodium-dependent multivitamin transporter (SMVT) on rabbit corneal epithelial cells. Primary cultured rabbit corneal epithelial cells (rPCECs)and freshly excised rabbit corneas were used for characterization of biotin uptake and transport
María Romo-Vaquero et al.
PloS one, 9(4), e94687-e94687 (2014-04-16)
Carnosic acid (CA) and rosemary extracts (RE) show body-weight, energy metabolism and inflammation regulatory properties in animal models but the mechanisms are not yet understood. Gut microbiota plays an important role in the host metabolism and inflammatory status and is
Kinetics of Valeric Acid Ketonization and Ketenization in Catalytic Pyrolysis on Nanosized SiO2, ?-Al2O3, CeO2/SiO2, Al2O3/SiO2 and TiO2/SiO2
Kulyk K, et al.
ChemPhysChem (2017)
S Vilska et al.
Maturitas, 5(2), 97-104 (1983-08-01)
Serum high-density lipoprotein cholesterol (HDL cholesterol), total cholesterol and triglyceride concentrations were determined in 158 post-menopausal women following long-term oral hormone replacement therapy. Oestradiol valerate (2 mg/day) was taken by 53 of the women and oestriol succinate (2 mg/day) by
Frank M Andrews et al.
American journal of veterinary research, 67(11), 1873-1882 (2006-11-03)
To compare the effects of hydrochloric acid (HCl) and various concentrations of volatile fatty acids (VFAs) on tissue bioelectric properties of equine stomach nonglandular (NG) mucosa. Gastric tissues obtained from 48 adult horses. NG gastric mucosa was studied by use
A K Singh et al.
Letters in applied microbiology, 46(3), 350-357 (2008-01-29)
To boost short-chain-length-long-chain-length polyhydroxyalkanoate (SCL-LCL-PHA) co-polymer yield in Pseudomonas aeruginosa MTCC 7925 by manipulating culture conditions. Stationary phase culture of P. aeruginosa MTCC 7925 was subjected to various doses of different carbons and, N and P deficiencies. Enhanced co-polymer yield
Pingxi Xu et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(46), 16592-16597 (2014-10-29)
Insect repellents are important prophylactic tools for travelers and populations living in endemic areas of malaria, dengue, encephalitis, and other vector-borne diseases. DEET (N,N-diethyl-3-methylbenzamide) is a 6-decade-old synthetic repellent, which is still considered the gold standard of mosquito repellents. Mosquitoes
Shilpi Khanna et al.
Journal of industrial microbiology & biotechnology, 34(6), 457-461 (2007-02-03)
The capability of different organic acids to produce a derivative of PHB [poly(3-hydroxybutyric-co-3-hydroxyvaleric acid), P(3HB-co-3HV)] was examined in shake flask cultivations. Propionic and valeric acids demonstrated the potential to produce P(3HB-co-3HV) under nitrogen limiting conditions at 30 degrees C. The
D S Wilbur et al.
Bioconjugate chemistry, 12(4), 616-623 (2001-07-19)
An investigation was conducted in which the stabilities of four structurally different biotin derivatives were assessed with regard to biotinamide bond hydrolysis by the enzyme biotinidase. The biotin derivatives studied contained an extra methylene in the valeric acid chain of
Michael Sarlea et al.
ChemSusChem, 5(1), 200-205 (2011-12-23)
Supercritical nitrile hydrolysis can be used for both, amide and acid production as well as waste water treatment, as the hydrolysis products show good biodegradability. The conventional process at ambient conditions requires large amounts of mineral acid or base. Approaches
Rabiâa Merrouche et al.
Journal of natural products, 73(6), 1164-1166 (2010-05-29)
Three new antibiotics were isolated from the fermentation broth of Saccharothrix algeriensis NRRL B-24137 and characterized as the dithiolopyrrolone derivatives valerylpyrrothine (1), isovalerylpyrrothine (2), and formylpyrrothine (3) as well as the known antibiotic aureothricin. The production of the dithiolopyrrolone derivatives
V U Täuber
Arzneimittel-Forschung, 26(7b), 1479-1484 (1976-01-01)
Percutaneous absorption of 6alpha,9-difluoro-11beta-hydroxy-16alpha-methyl-21-valeryloxy-1,4-pregnadiene-3,20-dione (difucortolone valerate, Nerisona) as dependent on the base, the concentration in the base and the condition of the skin was investigated in man and in guinea pigs. In addition the distribution of the corticoid in the
Tang-Chia Chung et al.
Journal of chromatography. A, 1156(1-2), 259-263 (2007-03-22)
A simple and sensitive isocratic liquid chromatographic method was developed for the analysis of isovaleric and valeric acids in human urine as biomarkers in metabolic acidosis. The method is based on the derivatization of isovaleric and valeric acids with a
D M Saunders et al.
The Australian & New Zealand journal of obstetrics & gynaecology, 18(3), 198-201 (1978-08-01)
The effect of oestradiol valerate on levels of blood cholesterol, triglycerides, free oestradiol and coagulation factors, as well as on urinary oestrogens and free cortisol was measured in 10 oöphorectomised women. Despite the very high urinary oestrogen levles obtained, there
Fátima Camões et al.
Biochimica et biophysica acta, 1853(1), 111-125 (2014-10-14)
Peroxisomes are ubiquitous organelles which participate in a variety of essential biochemical pathways. An intimate interrelationship between peroxisomes and mitochondria is emerging in mammals, where both organelles cooperate in fatty acid β-oxidation and cellular lipid homeostasis. As mitochondrial fatty acid
Cristiane Patrícia de Oliveira et al.
Journal of chromatography. A, 1244, 61-68 (2012-05-23)
A method consisting of multiple headspace solid-phase microextraction followed by gas chromatography-mass spectrometry analysis was developed and used to determine the main volatile radiolysis products formed by γ-irradiation of flexible multilayer food packaging samples. The developed method allows the use
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