76-02-8

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Showing 1-8 of 8 results for "76-02-8" within Papers

Association between interleukin-8 gene alleles and human susceptibility to tuberculosis disease.

Xin Ma et al.

The Journal of infectious diseases, 188(3), 349-355 (2003-07-19)

Interleukin (IL)-8 is involved in the pathogenesis of human tuberculosis (TB). However, the contribution of polymorphisms of the IL-8 gene and its receptor genes CXCR-1 and CXCR-2 to human TB susceptibility remains untested. In a case-control study, white subjects with

Biochemical characterization of a recombinant pullulanase from Thermococcus kodakarensis KOD1.

T Han et al.

Letters in applied microbiology, 57(4), 336-343 (2013-06-25)

In this report, a glycoside hydrolase 13 family pullulanase gene (Tk0977) was cloned from a thermophilic anaerobic archaeon Thermococcus kodakarensis KOD1 (Pul-Tk). Pul-Tk encodes a protein of 765 amino acids including a putative 22-residue signal peptide. The protein has four

Genetic variants of the renin-angiotensin-aldosterone system and reverse remodeling after cardiac resynchronization therapy.

Renata De Maria et al.

Journal of cardiac failure, 18(10), 762-768 (2012-10-09)

Reverse remodeling (RR) after cardiac resynchronization therapy (CRT) is associated with favorable clinical outcomes in heart failure (HF). The renin-angiotensin-aldosterone system (RAAS) is involved in the remodeling process. We assessed the association between RR and 8 common RAAS gene variants

Ovarian clear cell carcinomas: RHO GTPases may contribute to explain their singular biologic behavior.

Belen Canet et al.

Human pathology, 42(6), 833-839 (2011-01-07)

Ovarian clear cell carcinoma is found more often confined to the ovary (stage I) than high-grade serous carcinoma. The RHO GTPase family of proteins is involved in tumor invasion and metastasis through regulation of the cytoskeleton. The expression of several

Presence of Calcium-Like Tissue Composition in Carotid Plaque is Indicative of Significant Coronary Artery Disease in High-Risk Patients.

Julia E Herr et al.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 32(5), 633-642 (2019-03-04)

Grayscale pixel ranges from ultrasound images, indicating differences in atherosclerotic plaque echogenicity, have been shown to represent different tissue types. Our objective was to determine whether carotid plaque composition was correlated with severity of coronary artery disease (CAD) and risk

Heliox therapy in bronchiolitis: phase III multicenter double-blind randomized controlled trial.

Mina M Chowdhury et al.

Pediatrics, 131(4), 661-669 (2013-03-20)

Supportive care remains the mainstay of therapy in bronchiolitis. Earlier studies suggest that helium-oxygen therapy may be beneficial, but evidence is limited. We aimed to compare efficacy of 2 treatment gases, Heliox and Airox (21% oxygen + 79% helium or

Associations between cerebral small-vessel disease and Alzheimer disease pathology as measured by cerebrospinal fluid biomarkers.

Maartje I Kester et al.

JAMA neurology, 71(7), 855-862 (2014-05-14)

It remains unclear if and how associations between cerebral small-vessel disease and Alzheimer disease (AD) pathology lead to cognitive decline and dementia. To determine associations between small-vessel disease and AD pathology. Cross-sectional study from January 2002 to December 2012 using

Activity and safety of the multi-target tyrosine kinase inhibitor cabozantinib in patients with metastatic gastrointestinal stromal tumour after treatment with imatinib and sunitinib: European Organisation for Research and Treatment of Cancer phase II trial 1317 'CaboGIST'.

Patrick Schöffski et al.

European journal of cancer (Oxford, England : 1990), 134, 62-74 (2020-05-30)

Gastrointestinal stromal tumour (GIST) is commonly treated with tyrosine kinase inhibitors (TKIs), but most patients ultimately develop secondary resistance. Cabozantinib, a multi-targeted TKI inhibitor, has activity in patient-derived GIST mouse xenograft models and can overcome compensatory MET signalling occurring on

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