Search Within


Applied Filters:
Showing 1-30 of 325 results for "77-95-2" within Papers
Niels Peter Rønnow Sand et al.
JACC. Cardiovascular imaging, 11(11), 1640-1650 (2018-06-18)
This study sought to compare the per-patient diagnostic performance of coronary computed tomography angiography (CTA)-derived fractional flow reserve (FFRCT) with that of single-photon emission computed tomography (SPECT), using a fractional flow reserve (FFR) value of ≤0.80 as the reference for diagnosing
Akshay Bagai et al.
American heart journal, 187, 19-28 (2017-04-30)
Little is known about the use of platelet function testing to guide choice of P2Y We studied 671 myocardial infarction (MI) patients treated with percutaneous coronary intervention in the TRANSLATE-ACS Registry who had VerifyNow platelet function testing performed while on
Russia Ha-Vinh Leuchter et al.
JAMA, 312(8), 817-824 (2014-08-27)
Premature infants are at risk of developing encephalopathy of prematurity, which is associated with long-term neurodevelopmental delay. Erythropoietin was shown to be neuroprotective in experimental and retrospective clinical studies. To determine if there is an association between early high-dose recombinant
Satoshi Suetsugu et al.
Organic letters, 16(3), 996-999 (2014-01-28)
The total synthesis of (-)-aurantioclavine (1) was accomplished based on an intramolecular asymmetric amination of allyl carbonate 3 containing a p-tosylamide group. The reaction using tris(dibenzylideneacetone)dipalladium(0), tBu-phosphinooxazoline, and Bu4NCl in CH2Cl2 gave azepane 2 in 77% yield with 95% enantiomeric
Tommaso Cai et al.
The Journal of urology, 183(5), 1738-1743 (2010-03-20)
We evaluated the role of loss of heterozygosity on the interferon-alpha locus to predict the response to bacillus Calmette-Guerin therapy in patients with nonmuscle invasive bladder cancer. A total of 117 consecutive patients were selected, including 77 with nonmuscle invasive
Valérie Bonadona et al.
JAMA, 305(22), 2304-2310 (2011-06-07)
Providing accurate estimates of cancer risks is a major challenge in the clinical management of Lynch syndrome. To estimate the age-specific cumulative risks of developing various tumors using a large series of families with mutations of the MLH1, MSH2, and
Mohammad Reza Safarinejad et al.
The British journal of nutrition, 110(1), 164-171 (2012-12-04)
The main objective of the present study was to determine the potential of n-3 and n-6 fatty acids or coenzyme Q10 (CoQ10) to alter serum prostate-specific antigen (PSA) levels in normal healthy men. A total of 504 healthy men with
Andrew M Shaw et al.
The Analyst, 145(16), 5638-5646 (2020-07-09)
An evaluation of a rapid portable gold-nanotechnology measuring SARS-CoV-2 IgM, IgA and IgG antibody concentrations against spike 1 (S1), spike 2 (S) and nucleocapsid (N) was conducted using serum samples from 74 patients tested for SARS-CoV-2 RNA on admission to
Ramaswamy Govindan et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 4(2), 220-226 (2009-01-31)
To assess the efficacy and toxicity of carboplatin, etoposide, and exisulind as initial therapy for extensive stage small cell lung cancer. The Cancer and Leukemia Group B conducted a phase II study of carboplatin (area under the curve 6) day
Hiroshi Tsubamoto et al.
Anticancer research, 34(4), 2007-2014 (2014-04-03)
Recurrent ovarian clear cell carcinoma (CCC) rarely responds to cytotoxic agents. Itraconazole is a potent inhibitor of the P-glycoprotein efflux pump, angiogenesis, and the Hedgehog pathway. We evaluated the efficacy of chemotherapy with itraconazole for CCC. Medical charts of patients
Fabien Praz et al.
JACC. Cardiovascular interventions, 12(14), 1356-1365 (2019-05-28)
The aim of this study was to investigate the technical success and efficacy of mitral valve edge-to-edge repair using extended clip arms. A new iteration of the MitraClip system, the MitraClip XTR, was introduced in 2018 with the aim of
Tao Suo et al.
Emerging microbes & infections, 9(1), 1259-1268 (2020-05-23)
Quantitative real time PCR (RT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. However, due to the low viral load specimens and the limitations of RT-PCR, significant numbers of false negative reports are inevitable, which results
Mathieu Boulin et al.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 43(11), 905-911 (2011-08-02)
There is no consensus about the most effective method for transarterial chemoembolisation of hepatocellular carcinoma. The aim of this phase II trial was to compare the efficacy and toxicity of lipiodol transarterial chemoembolisation with amiodarone in association with pirarubicin or
Thijs M A van Dongen et al.
The New England journal of medicine, 370(8), 723-733 (2014-02-21)
Recent guidance for the management of acute otorrhea in children with tympanostomy tubes is based on limited evidence from trials comparing oral antibiotic agents with topical antibiotics. In this open-label, pragmatic trial, we randomly assigned 230 children, 1 to 10
C Itsiopoulos et al.
Nutrition, metabolism, and cardiovascular diseases : NMCD, 21(9), 740-747 (2010-08-03)
To investigate the impact of a diet modeled on the traditional Cretan Mediterranean diet on metabolic control and vascular risk in type 2 diabetes. Twenty-seven subjects (47-77 yrs) with type 2 diabetes were randomly assigned to consume either the intervention
Antonio Calles et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 10(12), 1726-1735 (2015-10-17)
Clinical responses to immune checkpoint blockade by anti-programmed cell death protein-1 (PD-1)/PD-L1 monoclonal antibodies in non-small-cell lung cancer (NSCLC) are associated with PD-L1 expression and smoking status. We aimed to determine the expression profile of PD-1 and its ligands, PD-L1
Matthew G Mei et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 23(11), 1861-1869 (2017-07-25)
High-dose therapy followed by autologous stem cell transplantation (ASCT) can improve outcomes for mantle cell lymphoma (MCL) but is associated with a high incidence of relapse. A retrospective study of 191 MCL patients who underwent ASCT at City of Hope
Elena López-Knowles et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 12(20 Pt 1), 6029-6036 (2006-10-26)
The aim was to analyze Tp53 and HDM2 in T1G3 bladder tumors and to determine the prognostic value of their alterations. Tumors (n = 119) were extracted from a prospective study of 1,356 bladder cancers. Tp53 mutations (exons 4-9) were
P Chaudhuri et al.
European journal of obstetrics, gynecology, and reproductive biology, 10(5), 325-328 (1980-06-01)
A double-blind controlled clinical trial of the new, not yet commercially available drug, carnidazole and tinidazole, was carried out in 77 women with a proven vaginal trichomoniasis. 39 patients and their sexual partners received a single dose of 2 g
Roger D James et al.
The Lancet. Oncology, 14(6), 516-524 (2013-04-13)
Chemoradiation became the standard of care for anal cancer after the ACT I trial. However, only two-thirds of patients achieved local control, with 5-year survival of 50%; therefore, better treatments are needed. We investigated whether replacing mitomycin with cisplatin in
C Shi et al.
Epidemiology and infection, 139(5), 674-682 (2010-06-08)
Genetic polymorphisms of the LMP/TAP gene coded by the HLA-II region may be associated with outcomes of HBV infection. We conducted a case-control study to test the hypothesis, including a persistent group of 155 patients with chronic hepatitis B and
Marije N van Doorn-van Atten et al.
The British journal of nutrition, 119(10), 1185-1194 (2018-05-16)
This study aimed to evaluate the effects of an intervention including nutritional telemonitoring, nutrition education, and follow-up by a nurse on nutritional status, diet quality, appetite, physical functioning and quality of life of Dutch community-dwelling elderly. We used a parallel
Selim Kortunay et al.
European addiction research, 18(4), 161-166 (2012-03-15)
Alcohol dependence causes serious problems which may be influenced by genetic factors associated with alcohol metabolism. The aim was to investigate the allelic and genotypic difference in distribution of a polymorphism in alcohol dehydrogenase 1C gene (ADH1C) between alcohol-dependent individuals
MaryFran R Sowers et al.
Arthritis and rheumatism, 54(8), 2481-2487 (2006-07-28)
To determine if levels of endogenous estrogen or estrogen metabolites are associated with an increased risk of developing knee osteoarthritis (OA) in women. Serum estradiol (E2) and 2 urinary estrogen metabolites (2-hydroxyestrone and 16alpha-hydroxyestrone) with radiographically defined prevalent and incident
Jesper Bonde et al.
International journal of cancer, 148(2), 396-405 (2020-10-01)
In human papillomavirus (HPV) cervical cancer screening, cytology is used as triage to counter the low specificity of HPV testing. VALID-SCREEN is a EU-multicenter, retrospective study conducted to evaluate the clinical performance of the FAM19A4/miR124-2 methylation-based molecular triage test as
Céu Figueiredo et al.
Journal of the National Cancer Institute, 94(22), 1680-1687 (2002-11-21)
Both Helicobacter pylori genotype and host genetic polymorphisms play a role in determining the clinical consequences of H. pylori infection. We investigated whether there are any combinations of bacterial and host genotypes that are particularly associated with the occurrence of
Anders Møller Andersen et al.
Pancreas, 39(1), 26-30 (2009-09-16)
In acute pancreatitis (AP), rapid diagnosis and early treatment are of importance for clinical outcome. Urinary trypsinogen-2 has been suggested as a promising diagnostic marker; however, studies using the urinary trypsinogen-2 dipstick test (UTDT) have provided varying results. The study
Bruce G Haffty et al.
International journal of radiation oncology, biology, physics, 71(4), 1006-1013 (2008-02-12)
To evaluate the prognostic significance of cyclooxygenase-2 (COX-2) in breast cancer patients treated with conservative surgery and radiation therapy (CS+RT). Between 1975 and 2003, we retrieved specimens from 504 breast cancer patients treated with CS+RT. The specimens were constructed into
Bridget E Barber et al.
Journal of clinical microbiology, 51(4), 1118-1123 (2013-01-25)
Plasmodium knowlesi can cause severe and fatal human malaria in Southeast Asia. Rapid diagnosis of all Plasmodium species is essential for initiation of effective treatment. Rapid diagnostic tests (RDTs) are sensitive for detection of uncomplicated and severe falciparum malaria but
T Skaaby et al.
The British journal of dermatology, 171(6), 1407-1414 (2014-03-19)
Loss-of-function mutations in the filaggrin gene (FLG) could have opposing effects on cancer risk, as mutations are associated with both 10% higher serum vitamin D levels, which may protect against cancer, and with impaired skin barrier function, which may lead
Page 1 of 11
Page 1 of 11