Amit Kumar Srivastava et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(14), 4411-4416 (2015-04-02)
Cancer stem cells (CSCs) with enhanced tumorigenicity and chemoresistance are believed to be responsible for treatment failure and tumor relapse in ovarian cancer patients. However, it is still unclear how CSCs survive DNA-damaging agent treatment. Here, we report an elevated