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Yangyang Huang et al.
Chemosphere, 218, 449-457 (2018-11-30)
Tris (2-butoxyethyl) phosphate (TBOEP) is a ubiquitous environmental contaminant due to its overuse. TBOEP has been found to cause reproductive toxicity and endocrine disruption during acute toxic experiment. In this study, we examined the effects of TBOEP on growth in
David Linnard Wheeler et al.
The New phytologist, 222(1), 497-510 (2018-10-30)
The fungus Verticillium dahliae causes wilts of several hundred plant species, including potato and mint. Verticillium spp. also colonize sympatric hosts such as mustards and grasses as endophytes. The evolutionary history of and interactions between pathogenic and endophytic of this
Denise Peserico et al.
Antioxidants (Basel, Switzerland), 9(4) (2020-04-29)
While reperfusion is crucial for survival after an episode of ischemia, it also causes oxidative stress. Nuclear factor-E2-related factor 2 (Nrf2) and unfolded protein response (UPR) are protective against oxidative stress and endoplasmic reticulum (ER) stress. Ezetimibe, a cholesterol absorption
Naveena Singh et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 31(4), 652-659 (2017-11-18)
A previous multicenter study of 67 cases of Stage I/II tubo-ovarian high-grade serous carcinoma with complete tubal sampling identified 7 cases in which there were only two disease sites, comprising tumor involving opposite adnexa with no extra-adnexal involvement. This study
Amanda L Silveira et al.
Journal of agricultural and food chemistry, 66(32), 8630-8638 (2018-07-19)
In this work, a GC-MS/MS method was developed for the determination of anabolic-agent residues in bovine urine. The optimized sample preparation was as follows: enzymatic hydrolysis by β-glucuronidase-sulfatase enzyme from Helix pomatia for 16 h at 37.5 °C, liquid-liquid extraction
Cristiane M Ida et al.
American journal of clinical pathology, 148(4), 296-307 (2017-10-03)
To develop and evaluate a real-time methylation-specific polymerase chain reaction (RT-MSP) MGMT assay, with a particular focus on small biopsies and indeterminate testing results. We assessed formalin-fixed paraffin-embedded glioblastoma or gliosarcoma specimens (n = 641). A test-validation group (n =
Inger Johansson et al.
Endocrinology, 149(5), 2191-2199 (2008-01-26)
Progenitor cells in the subgranular zone of the hippocampus may be of significance for functional recovery after various injuries because they have a regenerative potential to form new neuronal cells. The hippocampus has been shown to express the GH secretagogue
Shu Harn Te et al.
Applied and environmental microbiology, 81(15), 5203-5211 (2015-05-31)
The increasing occurrence of harmful cyanobacterial blooms, often linked to deteriorated water quality and adverse public health effects, has become a worldwide concern in recent decades. The use of molecular techniques such as real-time quantitative PCR (qPCR) has become increasingly
Kuan Sun et al.
Scientific reports, 6, 39797-39797 (2016-12-23)
Ancestry inference is of great interest in diverse areas of scientific researches, including the forensic biology, medical genetics and anthropology. Various methods have been published for distinguishing populations. However, few reports refer to sub-populations (like ethnic groups) within Asian populations
L M Evans et al.
Heredity, 114(4), 387-396 (2015-01-15)
Studies of genetic variation can clarify the role of geography and spatio-temporal variation of climate in shaping demography, particularly in temperate zone tree species with large latitudinal ranges. Here, we examined genetic variation in narrowleaf cottonwood, Populus angustifolia, a dominant
C Chen et al.
Heredity, 119(2), 95-106 (2017-04-06)
Inferring past demography is a central question in evolutionary and conservation biology. It is, however, sometimes challenging to disentangle their roles of contemporary versus historical processes in shaping the current patterns of genetic variation in endangered species. In this study
Yasuyuki Kubo et al.
mBio, 6(5), e01305-e01315 (2015-09-17)
The cucumber anthracnose fungus Colletotrichum orbiculare forms specialized cells called appressoria for host penetration. We identified a gene, FAM1, encoding a novel peroxin protein that is essential for peroxisome biogenesis and that associates with Woronin bodies (WBs), dense-core vesicles found
Deniz Mengüllüoğlu et al.
PloS one, 14(5), e0216549-e0216549 (2019-05-11)
The Caucasian lynx, Lynx lynx dinniki, has one of the southernmost distributions in the Eurasian lynx range, covering Anatolian Turkey, the Caucasus and Iran. Little is known about the biology and the genetic status of this subspecies. To collect baseline
Quanzhen Liu et al.
Ecotoxicology and environmental safety, 181, 241-247 (2019-06-15)
The coexistence of parent polycyclic aromatic hydrocarbons (PPAHs) and halogenated PAHs (HPAHs) in drinking water has generated much concern recently. However, a method to simultaneously determine these compounds has not been developed. In this study, a method using solid-phase extraction
Erin M Euliano et al.
Scientific reports, 9(1), 11372-11372 (2019-08-08)
Reverse transcription polymerase chain reaction (RT-PCR) is the gold standard for the molecular diagnosis of many infectious diseases, including RNA viruses, but is generally limited to settings with access to trained personnel and laboratory resources. We have previously reported a
Eunhee Kim et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 40(4), 885-894 (2019-05-17)
The lack of inclusion of comorbidities in animal models of stroke may underlie the limited development of therapy in stroke. Previous studies in mice deficient of CD36, an immune receptor, indicated its contribution to stroke-induced inflammation and injury in hyperlipidemic
S Sıddık Cindoruk et al.
Environmental science and pollution research international, 23(24), 24504-24513 (2016-04-21)
Wet deposition fluxes of organochlorine pesticides (OCPs) were determined for rain samples collected in a coastal area of Turkey. Seventeen precipitation samples were collected over a 1-year period from 2008 to 2009. Rainwater was accumulated at the beginning of rain
Jinjiang Pang et al.
Peptides, 31(4), 630-638 (2009-11-26)
Growth hormone-releasing peptides (GHRP) and ghrelin are synthetic and natural ligands of growth hormone secretagogue receptor (GHSR) respectively and are shown to exert protective actions on cardiac dysfunction. Because ghrelin has been reported to inhibit proinflammatory responses in human endothelium
Irina Zvereva et al.
Journal of proteomics, 149, 85-97 (2016-10-26)
Small peptides with a molecular weight of <2kDa represent a performance-enhancing substances. However, in vivo studies with human volunteers are limited because most of these peptides are not approved for human consumption. Thus, relevant in vitro models are a basic
Celine Vanhee et al.
Talanta, 142, 1-10 (2015-05-25)
Recent advances in genomics, recombinant expression technologies and peptide synthesis have led to an increased development of protein and peptide therapeutics. Unfortunately this goes hand in hand with a growing market of counterfeit and illegal biopharmaceuticals, including substances that are
David Kliman et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 24(5), 1069-1078 (2018-01-07)
Current techniques to assess chimerism after hematopoietic stem cell transplantation (HSCT) are limited in both sensitivity and precision. These drawbacks are problematic in the context of cellular therapies that frequently result in microchimerism (donor chimerism <1%). We have developed a
Ya Liu et al.
PloS one, 12(9), e0185280-e0185280 (2017-09-28)
Acipenser dabryanus is listed as a Critical Endangered species in the IUCN Red List and the first class protected animals in China. Fortunately, A. dabryanus specimens are being successfully bred in captivity for conservation. However, for effective ex situ conservation
Tong Liu et al.
Environmental pollution (Barking, Essex : 1987), 270, 116269-116269 (2020-12-19)
The enantioselective toxic effect and environmental behavior of chiral pesticides have attracted increasing research attention. In this study, the enantioselective toxicity and residues of hexaconazole (HEX) in earthworms (Eisenia fetida) were investigated. In the present study, significant enantioselective degradation characteristics
Sharna Tanzima Nuhat et al.
Cancer science, 109(5), 1682-1689 (2018-03-02)
Angioimmunoblastic T-cell lymphoma (AITL) is a subtype of nodal peripheral T-cell lymphoma (PTCL). Somatic RHOA mutations, most frequently found at the hotspot site c.50G > T, p.Gly17Val (G17V RHOA mutation) are a genetic hallmark of AITL. Detection of the G17V RHOA mutations
Dominik Barisic et al.
Stem cell research & therapy, 11(1), 79-79 (2020-02-24)
Many studies have elegantly shown that murine and rat bone marrow-derived mesenchymal stromal cells (bmMSCs) contribute to muscle regeneration and improve muscle function. Yet, the ability of transplanted human bmMSCs to manifest myogenic potential shows conflicting results. While human adipose-
Alba Medrano et al.
Scientific reports, 10(1), 19219-19219 (2020-11-07)
The widespread decline of canopy-forming macroalgal assemblages has been documented in many regions during the last decades. This pattern is often followed by the replacement of structurally complex algal canopies by more simplified habitats (e.g., turfs or sea urchin barren
Rajeev Rai et al.
Nature communications, 11(1), 4034-4034 (2020-08-14)
Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency with severe platelet abnormalities and complex immunodeficiency. Although clinical gene therapy approaches using lentiviral vectors have produced encouraging results, full immune and platelet reconstitution is not always achieved. Here we show that
Marcin Wiśniewski et al.
Experimental parasitology, 163, 1-7 (2016-01-23)
Hookworms are intestinal nematodes that infect up to 740 million people, mostly in tropical and subtropical regions. Adult worms suck blood from damaged vessels in the gut mucosa, digesting hemoglobin using aspartic-, cysteine- and metalloproteases. Targeting aspartic hemoglobinases using drugs
Marin Talbot Brewer et al.
Phytopathology, 105(6), 815-824 (2015-02-25)
Combining population genetics with epidemiology provides insight into the population biology of pathogens, which could lead to improved management of plant diseases. Gummy stem blight, caused by three closely related species of Stagonosporopsis-Stagonosporopsis cucurbitacearum (syn. Didymella bryoniae), S. citrulli, and
Siobhan Simpson et al.
Cancers, 12(9) (2020-08-29)
Dogs develop osteosarcoma (OSA) and the disease process closely resembles that of human OSA. OSA has a poor prognosis in both species and disease-free intervals and cure rates have not improved in recent years. Gene expression in canine OSAs was
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