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Thomas McNerney et al.
mAbs, 7(2), 413-428 (2015-02-24)
High titer (>10 g/L) monoclonal antibody (mAb) cell culture processes are typically achieved by maintaining high viable cell densities over longer culture durations. A corresponding increase in the solids and sub-micron cellular debris particle levels are also observed. This higher burden
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
Nutrient supplements boost yeast transformation efficiency.
Yu SC, et al.
Scientific Reports, 6, 35738-35738 (2016)
The cocoon of the fossorial frog Cyclorana australis functions primarily as a barrier to water exchange with the substrate.
Reynolds SJ, et al.
Physiological and Biochemical Zoology : Pbz, 83, 877-877 (2010)
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Katrin K, et al.
Angewandte Chemie (International Edition in English), 49, 6288-6308 (2010)
Protein crystallization: the growth of large-scale single crystals.
G L Gilliland et al.
Methods in enzymology, 104, 370-381 (1984-01-01)
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
L. Olsson et al.
Methods in Enzymology, 92, 10-10 (1983)
Cara J Ellison et al.
Current biology : CB, 30(15), 2974-2983 (2020-07-11)
Pathogenic bacteria enter the cytosol of host cells through uptake into bacteria-containing vacuoles (BCVs) and subsequent rupture of the vacuolar membrane [1]. Bacterial invaders are sensed either directly, through cytosolic pattern-recognition receptors specific for bacterial ligands, or indirectly, through danger
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
C Zeng et al.
Analytical biochemistry, 189(2), 197-201 (1990-09-01)
Poly(ethylene glycol)n is a group of water-soluble, hydrophobic, optically transparent and biomacromolecule-nondenaturing polymers. These properties have caused it be widely used for various purposes in the biological sciences. In this study, the effects of poly(ethylene glycol)n on protein preservation, electrotransferring
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