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Showing 1-30 of 65 results for "83-46-5" within Papers
Peiguo G Chu et al.
The American journal of surgical pathology, 29(3), 359-367 (2005-02-24)
Pancreatobiliary and ampulla of Vater adenocarcinomas frequently metastasize to regional lymph nodes, liver, or lung and are difficult to diagnose because they lack specific immunohistochemical markers. We studied the expression of cytokeratin 7 (CK7), cytokeratin 17 (CK17), cytokeratin 20 (CK20)
Zhanyong Shu et al.
Biochemistry, 43(16), 4781-4790 (2004-04-21)
Suv3 of Saccharomyces cerevisiae has been classified as a mitochondrial RNA helicase. However, the helicase domain in both yeast and human SUV3 varies considerably from the typical RNA helicase motifs. To investigate its enzymatic activities, a homogeneously purified preparation of
Simona Lamba et al.
PloS one, 4(8), e6833-e6833 (2009-09-01)
Frequent somatic mutations have recently been identified in the ras-like domain of the heterotrimeric G protein alpha-subunit (GNAQ) in blue naevi 83%, malignant blue naevi (50%) and ocular melanoma of the uvea (46%). The mutations exclusively affect codon 209 and
T Satoh et al.
The Journal of biological chemistry, 271(44), 27919-27926 (1996-11-01)
To gain additional insights into the negative gene regulatory action by triiodothyronine (T3), we isolated a 2-kilobase pair 5'-flanking region of the mouse preprothyrotropin-releasing hormone (ppTRH) gene and characterized the DNA elements mediating inhibitory regulation by T3 in the promoter
J H Kim et al.
Archives of oral biology, 46(4), 335-341 (2001-03-29)
Complementary DNA fragments which showed differential expression relative to unstressed controls were identified and isolated from human oral keratinocytes exposed to hyperosmotic stress. The up- or downregulation of the expression of nine of these cDNAs in response to osmotic stress
Sunil Kumar et al.
Journal of gastroenterology and hepatology, 27(12), 1825-1830 (2012-09-20)
Lactase non-persistence is common in India. We evaluated: (i) frequency of lactase gene (C/T-13910 and G/A-22018) polymorphisms in irritable bowel syndrome (IBS) and healthy controls (HC), (ii) association between these polymorphisms and IBS-subtypes and symptoms. A total of 150 IBS
V E Dosenko et al.
TSitologiia i genetika, 39(2), 49-54 (2005-09-16)
Endothelial NO-synthase (eNOS) gene allelic polymorphism in 221 patients with acute coronary syndrome and in 83 practically healthy people was determined. It was shown that interrelations of normal homozygotes, heterozygotes and pathologic homozygotes in T/C promoter polymorphism analysis accout 48%
Rui Sun et al.
The Journal of biological chemistry, 294(31), 11840-11852 (2019-06-16)
Eukaryotic translation initiation factor 4E (eIF4E)-binding protein 1 (4E-BP1) inhibits cap-dependent translation in eukaryotes by competing with eIF4G for an interaction with eIF4E. Phosphorylation at Ser-83 of 4E-BP1 occurs during mitosis through the activity of cyclin-dependent kinase 1 (CDK1)/cyclin B
V Ie Dosenko et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 51(1), 72-76 (2005-04-02)
Frequency of promoter endothelial NO-synthase gene allelic polymorphism by using polymerase chain reaction and restriction fragment length polymorphism (RFLP-PCR) was determined in 221 patients with acute coronary syndrome (ACS) and in 83 almost healthy subjects. Data obtained indicate that different
H J DeAizpurua et al.
Diabetes, 41(9), 1182-1187 (1992-09-01)
To detect serum antibodies to GAD in subjects with IDDM, three recombinant mBGAD 67 peptides encompassing the full-length protein were used in an ELISA. In this study 7 of 9 (78%) preclinical IDDM subjects (ICA+ first-degree relatives of a person
A Münch et al.
Alimentary pharmacology & therapeutics, 37(8), 795-798 (2013-02-26)
Microscopic colitis (MC) is a common chronic diarrhoeal disease, and remission can be induced with budesonide. However, diarrhoea relapses frequently when budesonide is tapered and a few patients become budesonide intolerant. To examine retrospectively the effect of azathioprine (AZA) and
P De Vries et al.
Naunyn-Schmiedeberg's archives of pharmacology, 359(4), 331-338 (1999-05-27)
The 5-hydroxytryptamine (5-HT)-induced late depressor response in rats is mainly mediated by vascular 5-HT7 receptors. The present study was devoted to determining the systemic and regional haemodynamic changes during this response, with particular emphasis on localising vascular beds that may
Jonathan L Slaughter et al.
Pediatrics, 131(4), 716-723 (2013-03-13)
To determine (1) between-hospital variation in diuretic use for infants with bronchopulmonary dysplasia (BPD), including hospital-specific treatment frequency, treatment duration, and percentage of infants receiving short (≤5 consecutive days) versus longer (>5 days) courses, and to determine (2) demographic and
G E Hanks et al.
International journal of radiation oncology, biology, physics, 13(4), 499-505 (1987-04-01)
This report extends the follow-up of patients studied in the Patterns of Care Survey of Prostate Cancer treated in the United States between 1973 and 1975 from a maximum of 5 years to a maximum of 10 years. Survival for
Ronald López-Cepero et al.
Boletin de la Asociacion Medica de Puerto Rico, 105(1), 14-17 (2013-06-19)
The presence of a major congenital anomaly is a frequent indication for late termination of pregnancy. The possibility of the fetus being born alive is significant, thus, feticide prior to the procedure is desirable. The purpose of this study was
Linda J Kay et al.
Pulmonary pharmacology & therapeutics, 23(2), 71-77 (2009-11-06)
The aim of the present study was to establish whether polymorphisms, especially those within the promoter region, of the beta(2)-adrenoceptor gene (ADRB2) influence beta(2)-adrenoceptor expression in human lung. The density of beta-adrenoceptors in human lung tissue (n=88) was determined by
Daniel Bergemalm et al.
Haematologica, 106(11), 2947-2959 (2020-10-16)
In X-linked thrombocytopenia with thalassemia (XLTT; OMIM 314050), caused by the mutation p.R216Q in exon 4 of the GATA1 gene, male hemizygous patients display macrothrombocytopenia, bleeding diathesis and a β-thalassemia trait. Herein, we describe findings in two unrelated Swedish XLTT
E F Hensen et al.
Clinical endocrinology, 75(5), 650-655 (2011-05-13)
Head and neck paragangliomas (HNPGL) are associated with mutations in genes encoding subunits of succinate dehydrogenase (SDH). The aim of this study was to evaluate SDH mutations, family history and phenotypes of patients with HNPGL in the Netherlands. We evaluated
L A Ferrara et al.
Journal of cardiovascular pharmacology, 18 Suppl 5, S19-S21 (1991-01-01)
Abnormalities of glucose and lipoprotein metabolism have frequently been found in hypertensive patients in both epidemiological and clinical studies. Reduction of blood pressure favorably affects the rate of cardiovascular diseases mainly when concomitant with a decrease in glucose and lipid
Isabella Venza et al.
Epigenetics, 7(11), 1315-1330 (2012-10-12)
We have recently reported that in astrocytoma cells the expression of interleukin-8 (IL-8) is upregulated by prostaglandin E2 (PGE2). Unfortunately, the exact mechanism by which this happens has not been clarified yet. Here, we have investigated whether IL-8 activation by
Iwona Bukowska-Ośko et al.
PloS one, 10(5), e0125604-e0125604 (2015-05-02)
Association between hepatitis C virus (HCV) quasispecies and treatment outcome among patients with chronic hepatitis C has been the subject of many studies. However, these studies focused mainly on viral variable regions (E1 and E2) and usually did not include
A Sardi et al.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 39(11), 1207-1213 (2013-09-07)
Cytoreductive surgery (CRS)/hyperthermic intraperitoneal chemotherapy (HIPEC) is the procedure of choice in patients with peritoneal dissemination from appendiceal cancer. Although recurrence rates are 26%-44% after first CRS/HIPEC, the role of repeated CRS/HIPEC has not been well defined. We hypothesize that
Guillermo L Chantada et al.
Pediatric blood & cancer, 61(5), 821-826 (2013-11-19)
Few studies were reported from developing countries regarding patient outcome and ocular survival in children with bilateral retinoblastoma treated with chemoreduction compared to external beam radiotherapy (EBRT). We undertook a retrospective study of three treatment eras: (1) (1988-1995) n =
C Kupatt et al.
Arteriosclerosis, thrombosis, and vascular biology, 20(10), 2226-2232 (2000-10-14)
Reperfusion injury after coronary occlusion is in part mediated by leukocyte activation and adhesion. Platelets may interact with polymorphonuclear granulocytes (PMNs), causing aggravated reperfusion injury. We studied whether c7E3Fab, a chimeric Fab fragment blocking platelet glycoprotein (GP) IIb/IIIa, decreases PMN-platelet-dependent
P G J ter Horst et al.
Journal of clinical pharmacy and therapeutics, 39(5), 541-544 (2014-07-06)
Depression during pregnancy is common and includes risks for mother and child. Pharmacokinetics of venlafaxine may be changed during pregnancy. This study aimed to describe changes in metabolic ratios and concentrations of venlafaxine and its main metabolite O-desmethylvenlafaxine during and
Elena Ricart et al.
The American journal of gastroenterology, 97(7), 1763-1768 (2002-07-24)
5-Aminosalicylate is metabolized in colonic mucosa by N-acetyltransferase 1 (NAT1), and sulfapyridine is metabolized in the liver by N-acetyltransferase 2 (NAT2). Common genetic polymorphisms in these enzymes result in rapid and slow acetylation. We determined the association between NAT1 genotype
T Pihlajaniemi et al.
The Journal of biological chemistry, 265(23), 13758-13766 (1990-08-15)
We have isolated and characterized overlapping cDNA clones which code for a previously unidentified human collagen chain. Although the cDNA-derived primary structure of this new polypeptide is very similar to the basement membrane collagen alpha 1(IV) and alpha 2(IV) chains
Jérôme Avouac et al.
Annals of the rheumatic diseases, 72(6), 1089-1098 (2012-11-20)
To investigate the contribution of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of dermal fibrosis on gene inactivation and targeted molecular strategies. Human skin expression of DNAM-1 was determined by immunohistochemistry. Mice deficient for DNAM-1 (dnam1-/-) and
Amelia Szymanowska et al.
Lung cancer (Amsterdam, Netherlands), 52(1), 9-14 (2006-02-28)
The aim of this study was to assess whether the TP53 Arg72Pro polymorphism is associated with an increased risk of non-small cell lung cancer (NSCLC). Additionally, in NSCLC patients, we investigated a potential association between this polymorphism and somatic TP53
Jérôme Avouac et al.
Annals of the rheumatic diseases, 72(6), 1089-1098 (2012-11-20)
To investigate the contribution of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of dermal fibrosis on gene inactivation and targeted molecular strategies. Human skin expression of DNAM-1 was determined by immunohistochemistry. Mice deficient for DNAM-1 (dnam1-/-) and
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